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Graph
Property Graph
Another Graph Example
Nodes Edges
Why graphs?
Queries: SQL v. Gremlin
select	p2.name,p1.post	from	posts	p1	
inner	join	persons	p2	
on	p1.to_id=p2.id	
where	p1.from_id	in(select	id	from	persons	where	name='keith');
graph.traversal().V().has('name','keith').outE('posts')
.as('msg').inV().as('who')
.select('msg',	'who')
.by('comment').by('name’)
Traversing a graph
Suggest to John that he might know
Jane
Traversing a graph
Traversing a graph
OLTP
On-Line	Transaction	Processing
OLAP
On-Line	Analytical	Processing
Graph Databases
Image	Reference:	Kelvin	Lawrence	&	Co
Graph Databases
Graph Databases Landscape
OLTP
• IBM	Graph
• Titan
• Neo4j
• OrientDB
• TAO
• Jena
OLAP
• Pregel
• Spark	GraphX
• Spark	GraphFrames
• Giraph
Questions?
u Prachi Khadke (pskhadke@us.ibm.com) or the
people wearing the Graph T-shirts!
u Sean Mulvehill (mulvehill@us.ibm.com)
The Social+Data Graph of Life Science
Barry Wark, PhD
ovation.io
Modern life science R&D is challenging
● $50B “Cottage industry” now globalized and highly collaborative
○ Distributed teams
○ Universities, clinicians, non-profit labs, CROs, Biotech, Pharma
● PB of data, millions experiments per year
● Science is complicated
R&D organizations are expected to produce efficient pipelines from
academic research to clinical development
70%
of data collected annually in life science goes “dark” — unaccessible,
undiscoverable or unuseable
$35B
of data collected annually in life science goes “dark” — unaccessible,
undiscoverable or unuseable
Why does data go dark?
?
Wark/Maslow hierarchy of scientific data needs
Data Storage
Metadata
Versioning
Collaboration
● Secure cloud storage
(HIPAA, 21 CFR 11)
● Metadata tied to files
● File/data Provenance across
collaborators and analyses
● Integrated annotation, chat
● Low threshold: continue to
use preferred capture,
analysis tools
A Scientific data layer stops data from
going dark
The Social+Data Graph
● Real-time
● Structural information: projects,
experiments, people
● High information events
○ Researcher annotation
○ Communication
○ File selection
Social+Data graph
● 350,000 Researchers
● O(100B) files
● Average academic researcher
writes 1 paper per year with 3
other colleagues in >1 countries
● k=8
● 40,000 users to a fully
connected graph
Global Social+Data graph
Assisting R&D organizations to mobilize
idle assets
1. Find relevant internal experts
2. Recommend existing, relevant data (and the resources to utilize it)
3. Identify the best external resources and opportunities
4. Organizational analytics
a. Who are the effective collaborators?
b. Which are the most valuable data sets?
Calculate (weighted) pairwise distances for all nodes using A*
● Shuffle rows & columns of the
matrix to minimize loss (spectral,
information, etc.)
● Well-studied in bioinformatics
(not that different) and text
classification
● NP-complete
● Clusters allow us to look up in
both directions
○ User → Data
○ Data → Users
○ (Users → Users)
Bi-cluster to identify
relevant groups
Data architecture
+ GraphX
Relevant, related people and data
Questions
Appendix
Publication graph
● Incomplete
● Late
● Post-hoc
Information-based co-clustering
https://cs.gmu.edu/~carlotta/publications/IBCC_TMW_final.pdf
https://pdfs.semanticscholar.org/4a3e/b95f17a88e14227b05a590639e8cd3346a99
.pdf

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