The Basics – Energy – to keep
you going
The body can create fuel from 3 sources, glucose, fat
and protein.
Glucose is the major source of energy for the brain and
nervous system.
The brain needs a constant source of glucose to
function.
Glucose is obtained through the diet
Glucose levels are regulated by the liver and pancreas
The Liver
The liver regulates blood glucose levels through 3
processes:
Glycogen synthesis (glycogenesis)
Glycogen breakdown (glycogenolysis)
Synthesis of Glucose from noncarb sources
(glyconeogenesis)
When blood glucose levels rise, glucose is removed
from the blood and converted to glycogen
When blood glucose levels fall, the liver breaks down
glycogen and releases the glucose to the body
The Pancreas
Hormonal control of blood glucose levels is regulated
by the pancreas. (insulin & glucagon)
The islets of Langerhans are the part of the pancreas
that secretes glucose regulating hormones (insulin,
glucagon)
Insulin lowers blood glucose levels by facilitating the
movement of glucose into body tissues
Glucagon maintains blood glucose levels by increasing
the release of glucose from the liver, into the
bloodstream.
Diabetes
When an imbalance of insulin availability and insulin
need results in a disorder of carbohydrate, fat and
protein metabolism
Type 1 – most commonly an autoimmune disorder.
Immune system attacks the pancreas (beta cells) and it
can no longer produce insulin
Type 2 – Insulin resistance and insulin deficiency
(impaired release of insulin)
Diabetes Type 1
The pancreas no longer produces insulin (beta
cell destruction)
Occurs most commonly in children – but can
occur at any age
People with DM1 require insulin several times
throughout the day
Diabetes Type 2
People with Type 2 DM produce insulin,
however the body cannot utilize the insulin
(insulin resistance).
Genetic and Acquired factors influence the
development of DM type 2
Diabetes Type 2
Risk Factors
Age –
11.3% of people over age 20
26.9% of people 65+ years
Genetics – Risk of developing DM:
15% if one parent is diabetic
75% if both parents are diabetic
Lifestyle – Poor diet
Excess Weight
Low Activity level
Gestational diabetes
Refers to glucose intolerance that develops during
pregnancy.
Occurs in 2-14% of pregnancies
Gestational diabetes makes the pregnancy “high risk”
Women who develop gestational diabetes have an
increased risk of developing type 2 diabetes within 10
years
Dietary Management
For the Type 1 diabetic managing his/her diet
important factors are to
*eat consistent amounts/types of food at routine
times
*monitor blood glucose levels
*use insulin as prescribed to prevent elevated blood
glucose levels
For the Type 2 diabetic managing his/her diet
includes
losing weight which improves diabetic control.
Ensuring food intake meets goals for maintaining
blood glucose levels.
Exercise
Exercise is not just good for the cardiovascular
system. In Type 2 diabetics decreased levels of
body fat allow for increased sensitivity to
insulin and improved blood glucose control.
Type 1 diabetics need to be careful when
exercising. Exercise increases glucose uptake
into the muscles. If insulin levels are not
adjusted for exercise there is a high chance of
hypoglycemia resulting, even HOURS after
exercise ends
Medications
Oral Meds
People with type 2 diabetes experience
Increased glucose production from the liver
Decreased utilization of carbohydrates
Impaired insulin secretion
Decreased insulin stimulated glucose uptake in muscles
Oral Antidiabetic Meds work on one or several of these
issues
Medications cont.
Insulin –All type 1 diabetics, and some type 2 diabetics
require insulin.
Insulin is categorized by time of onset and duration.
Insulin is given by the Subcut. or IV route
Insulin is given in set doses or based on a sliding scale