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Type 2 Diabetes
Presented by:- Surya pratap singh rajput
Batch-2017-18
Type 2: Overview
 Type 2 is the most common form of diabetes (DM).
 In this form, the body does not produce enough insulin
or the cells ignore the insulin that is produced.
 Insulin is required by the body in order to use sugar.
 Insulin takes the sugar from the blood into the cells.
 When glucose builds up in the blood instead of going
into cells, it can cause some problems:
• In the short-term, your cells may be starved for energy
• In time, high blood glucose may hurt your eyes, kidneys,
nerves, or heart.
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Insulin
 Inside the pancreas, beta cells make the hormone insulin.
 Beta cells release insulin to help the body use or store blood glucose from food.
 In people with type 1 diabetes, the pancreas no longer makes insulin.
 The beta cells have been destroyed and insulin shots are the only way to keep
blood glucose levels down.
 People with type 2 diabetes make insulin, but their bodies don't respond well to it.
 Only some people with type 2 diabetes need diabetes pills or insulin shots to help
their bodies use glucose for energy.
Who Gets Diabetes?
 Although diabetes occurs in people of all ages and races, some groups have
a higher risk for developing type 2 diabetes than others:
• African Americans
• Latinos
• Native Americans
• Asian American/Pacific Islanders
• Aged population
Conditions that can arise from Type
2 DM
 Hypoglycemia
 Hyperglycemia
 Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNS)
Hypoglycemia
 Hypoglycemia or low blood glucose (sugar) is a
problem that happens from time to time to
everyone who has diabetes.
 It is sometimes referred to as “insulin reaction.”
 Although it may be unavoidable at times, it is
important to know how to recognize and treat the
condition immediately before symptoms worsen.
Symptoms of Hypoglycemia
 Shakiness
 Dizziness
 Sweating
 Hunger
 Headache
 Pale skin color
 Sudden moodiness or behavior
changes, such as crying for
no apparent reason
 Clumsy or jerky movements
 Seizure
 Difficulty paying attention,
or confusion
 Tingling sensations around
the mouth
Low Blood Glucose
 You should check your blood glucose level according to
the schedule you work out with your doctor.
 In addition, you should check your blood glucose any
time you feel low blood glucose coming on.
 If you check and observe a low blood glucose level, then
treat for hypoglycemia quickly.
 A good rule if you are unable to check is:
“When in doubt, treat.”
Treating Hypoglycemia
 The quickest way to raise your blood glucose and treat hypoglycemia is with
some form of sugar, such as:
• 3 glucose tablets
• ½ cup of fruit juice
• 5-6 pieces of hard candy
 Once you have checked your blood glucose and treated the hypoglycemia,
wait 15 to 20 minutes and then recheck your blood again.
 If your blood sugar is still low and symptoms of hypoglycemia
haven’t went away, repeat treatment.
 If hypoglycemia is not treated quickly enough, you could pass out.
 If you pass out, you will need immediate treatment, such as an injection of
glucagon or emergency treatment in a hospital.
 Glucagon, like insulin, is injected.
 However, glucagon works to raise blood glucose.
 If you pass out from hypoglycemia, people should:
• NOT inject insulin
• NOT give you food or fluids
• NOT put their hands in your mouth
• Inject glucagon
• Call for emergency help
Hyperglycemia
 Hyperglycemia is the technical term for high blood glucose.
 It happens when the body has too little or not enough insulin or when the
body can’t use insulin properly.
 A number of factors can be the cause of hyperglycemia, including:
• Eating more than planned
• Exercising less than planned
• The stress of an illness, such as a cold or flu
• Other stresses, such as family conflicts or dating problems
Symptoms of Hyperglycemia
• High blood glucose
• High levels of sugar in the urine
• Frequent urination
• Increased thirst
 It is important to monitor blood glucose levels frequently.
 If hyperglycemia is detected, treatment should begin immediately.
 Failing to treat hyperglycemia could lead to a condition called
ketoacidosis
 Ketoacidosis occurs when the body doesn’t have enough insulin.
Without insulin, the body can’t use glucose for fuel, so it is left
breaking down fats for energy.
Hyperglycemia Leading to Ketosis
 Waste products (ketones) are generated as your body breaks down fats.
 Large amounts of ketones cannot be tolerated by the body.
 So, your body will try to excrete these ketones through the urine.
 However, not all will be excreted, causing the remaining to build up in the blood.
 This buildup leads to Ketosis.
Symptoms of Ketosis
 Shortness of breath
 Breath that smells fruity
 Nausea and vomiting
 A very dry mouth
How to Treat Hyperglycemia
 Exercise is often effective in lowering blood glucose levels.
 However, if your blood glucose is above 240 mg/dl, check your urine for ketones.
 If they are present, do NOT exercise.
 This can actually lead to higher blood glucose levels than prior to beginning
the exercise.
 You will need to work with your doctor on finding the best way to lower your blood
glucose level.
Hyperosmolar Hyperglycemic Nonketotic
Syndrome
 Referred to as HHNS
 It is a serious condition most frequently seen in older persons.
 Can occur in type 1 or type 2 diabetes, but is most commonly seen in type 2.
 HHNS is usually brought on by something else, such as an illness or infection
 In HHNS, blood sugar levels rise.
 Your body tries to rid itself of excess sugar by
passing it through the urine.
 Initially, you produce a lot of urine, and you have to
go to the bathroom often.
 With time, you may not have to go as often, and the
urine becomes very dark.
 You may be very thirsty.
 Even if you are not thirsty, it is very important to
consume a lot of liquids to prevent dehydration.
 If HHNS continues, severe dehydration can
potentially lead to:
• Seizures, coma, or even death
Hyperosmolar Hyperglycemic Nonketotic
Syndrome
Warning Signs of HHNS
 Blood sugar level over 600 mg/dl
 Dry, parched mouth
 Extreme thirst
(which may gradually disappear)
 Warm, dry skin that does
not sweat
 High fever
( > 101 degrees Fahrenheit)
 Sleepiness or confusion
 Loss of vision
 Hallucinations
(seeing/hearing things that aren’t there)
 Weakness on one side of the body
To prevent HHNS
 Check your blood sugar regularly.
 It’s best to speak with your doctor about how often you should check your
blood glucose and what your target range should be.
Importance of Monitoring Blood
Glucose
 Keeping your blood glucose in your target range
can help prevent or delay the start of diabetes
complications such as nerve, eye, kidney, and
blood vessel damage.
 Once an individual learns that he/she had diabetes,
it is important to work with your health care team to
create a diabetes care plan.
 The plan aims to balance the foods you eat
with your exercise, and, possibly, with diabetes
pills or insulin.
 There are two types of checks that you can do to
help keep track of how your plan is working:
• Blood glucose checks
• Urine ketone checks
Who Should Check?
 Experts feel that anyone with diabetes can benefit from checking their blood
glucose. The American Diabetes Association recommends blood glucose
checks if you have diabetes and are:
• Taking insulin or diabetes pills
• On intensive insulin therapy
• Pregnant
• Having a hard time controlling your blood glucose levels
• Having severe low blood glucose levels or ketones from high blood glucose levels
• Having low blood glucose levels without the usual warning signs
Urine Checks
 Not as accurate as blood glucose checks
 Should not be done unless blood testing is impossible
 A urine check for ketones is another matter.
 This is an important check when your diabetes is out of
control or when you are sick.
 When the body is burning fat instead of glucose, you could
expect to find moderate or large amounts of ketones in urine.
When to Test for Ketones
• Your blood glucose is more than 300 mg/dl
• You feel nauseated, are vomiting, or have abdominal pain
• You are sick (example– with a cold or the flu)
• You feel tired all the time
• You are thirsty or have a very dry mouth
• Your skin is flushed
• You have a hard time breathing
• Your breath smells “fruity”
• You feel confused or “in a fog”
Tight Control and Diabetes
 The benefit of tight control of blood glucose can
be in the prevention or slower progression of
many complications of diabetes, giving you extra
years of healthy, active life.
 Tight control is not for everyone, and it involves
hard work.
Tight Control- Not Recommended For:
 Children
• Having enough glucose in the blood is vital for brain
development. Controversy over what is the appropriate age
to start. Some doctors say age 13, others say 7 is fine.
 Elderly people
• Hypoglycemia can cause strokes and heart attacks in older
people. Also, the major goal of tight control is to prevent
complications many years later. Tight control is most
worthwhile for healthy people who can expect to live at least
10 more years.
Tight Control- Not Recommended For:
 Some individuals who already have complications
• For example, individuals with end-stage kidney disease or severe vision
loss probably should not try for tight control. Their complications are likely
to be too far along to receive benefits from tight control.
 Some individuals with diseases
• For some with coronary artery disease or vascular disease, tight control
is not indicated.
 Individuals with hypoglycemia unawareness
• It would not be safe for these people to attempt tight control.
Diabetes Medications
 In type 2 diabetes, when the initial treatment options fail
(meal planning, weight loss, and exercise) to control blood
glucose levels, the next step is taking a medicine that
lowers blood glucose levels.
 All diabetes pills sold today in the United States are
members of five classes of drugs:
• Sulfonylureas
• Meglitnides
• Biguanides
• Thiazolidnediones
• Aplha-glucosidase inhibitors
Thank you

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Diabetes.pptx

  • 1. Type 2 Diabetes Presented by:- Surya pratap singh rajput Batch-2017-18
  • 2. Type 2: Overview  Type 2 is the most common form of diabetes (DM).  In this form, the body does not produce enough insulin or the cells ignore the insulin that is produced.  Insulin is required by the body in order to use sugar.  Insulin takes the sugar from the blood into the cells.  When glucose builds up in the blood instead of going into cells, it can cause some problems: • In the short-term, your cells may be starved for energy • In time, high blood glucose may hurt your eyes, kidneys, nerves, or heart.
  • 3. 3 of 38 Insulin  Inside the pancreas, beta cells make the hormone insulin.  Beta cells release insulin to help the body use or store blood glucose from food.  In people with type 1 diabetes, the pancreas no longer makes insulin.  The beta cells have been destroyed and insulin shots are the only way to keep blood glucose levels down.  People with type 2 diabetes make insulin, but their bodies don't respond well to it.  Only some people with type 2 diabetes need diabetes pills or insulin shots to help their bodies use glucose for energy.
  • 4. Who Gets Diabetes?  Although diabetes occurs in people of all ages and races, some groups have a higher risk for developing type 2 diabetes than others: • African Americans • Latinos • Native Americans • Asian American/Pacific Islanders • Aged population
  • 5. Conditions that can arise from Type 2 DM  Hypoglycemia  Hyperglycemia  Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNS)
  • 6. Hypoglycemia  Hypoglycemia or low blood glucose (sugar) is a problem that happens from time to time to everyone who has diabetes.  It is sometimes referred to as “insulin reaction.”  Although it may be unavoidable at times, it is important to know how to recognize and treat the condition immediately before symptoms worsen.
  • 7. Symptoms of Hypoglycemia  Shakiness  Dizziness  Sweating  Hunger  Headache  Pale skin color  Sudden moodiness or behavior changes, such as crying for no apparent reason  Clumsy or jerky movements  Seizure  Difficulty paying attention, or confusion  Tingling sensations around the mouth
  • 8. Low Blood Glucose  You should check your blood glucose level according to the schedule you work out with your doctor.  In addition, you should check your blood glucose any time you feel low blood glucose coming on.  If you check and observe a low blood glucose level, then treat for hypoglycemia quickly.  A good rule if you are unable to check is: “When in doubt, treat.”
  • 9. Treating Hypoglycemia  The quickest way to raise your blood glucose and treat hypoglycemia is with some form of sugar, such as: • 3 glucose tablets • ½ cup of fruit juice • 5-6 pieces of hard candy  Once you have checked your blood glucose and treated the hypoglycemia, wait 15 to 20 minutes and then recheck your blood again.  If your blood sugar is still low and symptoms of hypoglycemia haven’t went away, repeat treatment.
  • 10.  If hypoglycemia is not treated quickly enough, you could pass out.  If you pass out, you will need immediate treatment, such as an injection of glucagon or emergency treatment in a hospital.  Glucagon, like insulin, is injected.  However, glucagon works to raise blood glucose.
  • 11.  If you pass out from hypoglycemia, people should: • NOT inject insulin • NOT give you food or fluids • NOT put their hands in your mouth • Inject glucagon • Call for emergency help
  • 12. Hyperglycemia  Hyperglycemia is the technical term for high blood glucose.  It happens when the body has too little or not enough insulin or when the body can’t use insulin properly.  A number of factors can be the cause of hyperglycemia, including: • Eating more than planned • Exercising less than planned • The stress of an illness, such as a cold or flu • Other stresses, such as family conflicts or dating problems
  • 13. Symptoms of Hyperglycemia • High blood glucose • High levels of sugar in the urine • Frequent urination • Increased thirst  It is important to monitor blood glucose levels frequently.  If hyperglycemia is detected, treatment should begin immediately.  Failing to treat hyperglycemia could lead to a condition called ketoacidosis  Ketoacidosis occurs when the body doesn’t have enough insulin. Without insulin, the body can’t use glucose for fuel, so it is left breaking down fats for energy.
  • 14. Hyperglycemia Leading to Ketosis  Waste products (ketones) are generated as your body breaks down fats.  Large amounts of ketones cannot be tolerated by the body.  So, your body will try to excrete these ketones through the urine.  However, not all will be excreted, causing the remaining to build up in the blood.  This buildup leads to Ketosis.
  • 15. Symptoms of Ketosis  Shortness of breath  Breath that smells fruity  Nausea and vomiting  A very dry mouth
  • 16. How to Treat Hyperglycemia  Exercise is often effective in lowering blood glucose levels.  However, if your blood glucose is above 240 mg/dl, check your urine for ketones.  If they are present, do NOT exercise.  This can actually lead to higher blood glucose levels than prior to beginning the exercise.  You will need to work with your doctor on finding the best way to lower your blood glucose level.
  • 17. Hyperosmolar Hyperglycemic Nonketotic Syndrome  Referred to as HHNS  It is a serious condition most frequently seen in older persons.  Can occur in type 1 or type 2 diabetes, but is most commonly seen in type 2.  HHNS is usually brought on by something else, such as an illness or infection
  • 18.  In HHNS, blood sugar levels rise.  Your body tries to rid itself of excess sugar by passing it through the urine.  Initially, you produce a lot of urine, and you have to go to the bathroom often.  With time, you may not have to go as often, and the urine becomes very dark.  You may be very thirsty.  Even if you are not thirsty, it is very important to consume a lot of liquids to prevent dehydration.  If HHNS continues, severe dehydration can potentially lead to: • Seizures, coma, or even death Hyperosmolar Hyperglycemic Nonketotic Syndrome
  • 19. Warning Signs of HHNS  Blood sugar level over 600 mg/dl  Dry, parched mouth  Extreme thirst (which may gradually disappear)  Warm, dry skin that does not sweat  High fever ( > 101 degrees Fahrenheit)  Sleepiness or confusion  Loss of vision  Hallucinations (seeing/hearing things that aren’t there)  Weakness on one side of the body
  • 20. To prevent HHNS  Check your blood sugar regularly.  It’s best to speak with your doctor about how often you should check your blood glucose and what your target range should be.
  • 21. Importance of Monitoring Blood Glucose  Keeping your blood glucose in your target range can help prevent or delay the start of diabetes complications such as nerve, eye, kidney, and blood vessel damage.  Once an individual learns that he/she had diabetes, it is important to work with your health care team to create a diabetes care plan.  The plan aims to balance the foods you eat with your exercise, and, possibly, with diabetes pills or insulin.  There are two types of checks that you can do to help keep track of how your plan is working: • Blood glucose checks • Urine ketone checks
  • 22. Who Should Check?  Experts feel that anyone with diabetes can benefit from checking their blood glucose. The American Diabetes Association recommends blood glucose checks if you have diabetes and are: • Taking insulin or diabetes pills • On intensive insulin therapy • Pregnant • Having a hard time controlling your blood glucose levels • Having severe low blood glucose levels or ketones from high blood glucose levels • Having low blood glucose levels without the usual warning signs
  • 23. Urine Checks  Not as accurate as blood glucose checks  Should not be done unless blood testing is impossible  A urine check for ketones is another matter.  This is an important check when your diabetes is out of control or when you are sick.  When the body is burning fat instead of glucose, you could expect to find moderate or large amounts of ketones in urine.
  • 24. When to Test for Ketones • Your blood glucose is more than 300 mg/dl • You feel nauseated, are vomiting, or have abdominal pain • You are sick (example– with a cold or the flu) • You feel tired all the time • You are thirsty or have a very dry mouth • Your skin is flushed • You have a hard time breathing • Your breath smells “fruity” • You feel confused or “in a fog”
  • 25. Tight Control and Diabetes  The benefit of tight control of blood glucose can be in the prevention or slower progression of many complications of diabetes, giving you extra years of healthy, active life.  Tight control is not for everyone, and it involves hard work.
  • 26. Tight Control- Not Recommended For:  Children • Having enough glucose in the blood is vital for brain development. Controversy over what is the appropriate age to start. Some doctors say age 13, others say 7 is fine.  Elderly people • Hypoglycemia can cause strokes and heart attacks in older people. Also, the major goal of tight control is to prevent complications many years later. Tight control is most worthwhile for healthy people who can expect to live at least 10 more years.
  • 27. Tight Control- Not Recommended For:  Some individuals who already have complications • For example, individuals with end-stage kidney disease or severe vision loss probably should not try for tight control. Their complications are likely to be too far along to receive benefits from tight control.  Some individuals with diseases • For some with coronary artery disease or vascular disease, tight control is not indicated.  Individuals with hypoglycemia unawareness • It would not be safe for these people to attempt tight control.
  • 28. Diabetes Medications  In type 2 diabetes, when the initial treatment options fail (meal planning, weight loss, and exercise) to control blood glucose levels, the next step is taking a medicine that lowers blood glucose levels.  All diabetes pills sold today in the United States are members of five classes of drugs: • Sulfonylureas • Meglitnides • Biguanides • Thiazolidnediones • Aplha-glucosidase inhibitors