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Secondary active transport
across the cell membrane
Biophysics
Na+/Ca2+ exchanger (NCX)
Na+/Ca2+ exchanger (NCX)
• NCX is involved in the mechanism of cardiac glycosides
Na+, glucose transporter
Glucose absorption in the small intestine
Na+, glucose transporter
Glucose reabsorption in the proximal tubules of kidneys
Lec3_secondary active transport UG ST.ppt
Lec3_secondary active transport UG ST.ppt
Lec3_secondary active transport UG ST.ppt
Urine production
Phase I - Filtration in Bowman's Capsule
Phase II - Reabsorption in the Proximal Tubule
Phase III - Creation of an Osmotic Gradient in the Loop of Henle
Phase IV - Regulating Water and Electrolyte Balance in the Distal Tubule and the
Collecting Duct:
Lec3_secondary active transport UG ST.ppt
Lec3_secondary active transport UG ST.ppt
Lec3_secondary active transport UG ST.ppt
The Na+/K+/2Cl- cotransporter (NKCC)
Secondary active transport
• H+/oligopeptide transporter (PepT)
• H+/neurotransmitter exchangers
Lec3_secondary active transport UG ST.ppt
Lec3_secondary active transport UG ST.ppt
Adenine nucleotide translocase

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Lec3_secondary active transport UG ST.ppt

Notas del editor

  1. * Uniporter – transports only one substance in one direction, for example CPx-ATPase, V-pump, ABC transporter.
  2. Inhibition of the Na+/K+-ATPase in vascular smooth muscle causes depolarization, which causes smooth muscle contraction and vasoconstriction.