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A Linked Open Data Approach to 
Interoperability between 
Biomedical Resource Inventories 
Trish Whetzel, Ph.D. 
Presenting on behalf of the Resource Coordination Group 
(Anita Bandrowski, Carlo Torniai, Charles Borromeo, Melissa 
Haendel, Jessica Tenenbaum)
Outline 
• Resourceome 
• Resource Inventory Projects 
• Interoperability 
• Future Plans
Accessing the “Resourceome”
• Machine-readable 
resource associated with 
a website 
• Resources are 
described in terms of an 
information model 
• Supported by the 
Biomedical Resource 
Ontology 
• Can be discovered by 
search engines such as 
Google 
Biositemaps 
www.biositemaps.org
Biositemaps 
National Centers for 
Biomedical Computing 
Clinical and Translational 
Science Awards 
www.ncbcs.org www.ctsaweb.org
Resource Discovery System: 
A catalog of > 1,400 biomedical resources 
A set of tools and services for easy sharing of and linking of resources to articles, websites etc. 
The tools ingest NIF resources.
Neuroscience Information Framework 
• A portal for finding and 
using resources 
• Resources are 
described in terms of an 
information model 
• Supported by the 
NIFSTD ontology 
• Provides simultaneous 
search of >30M database 
records, organized by 
www.neuinfo.org category
Neuroscience Information Framework 
MT 
WY 
ID 
WA 
OR 
NV 
UT 
CA 
AZ 
ND 
SD 
NE 
CO 
NM 
TX 
KS 
OK 
MO 
AR 
LA 
MN 
IA 
WI 
IL 
IN 
KY 
TN 
WV VA 
MS AL GA 
SC 
FL 
MI 
NY 
PA 
NJ 
DE 
ME 
CT 
MD 
RI 
MA 
VT 
NH 
AK 
HI 
NC 
PR 
Supported by the NIH Blueprint for Neuroscience
NIF Registry: 
A catalog of > 3,500 human curated databases, tools and materials 
A set of tools and services for easy sharing of and linking of data to articles, websites etc. 
The tools ingest Biositemaps and two other common resource description formats
eagle-i 
• Make scientific research 
resources more visible via a 
federated network 
• Resources are described in 
terms of an information 
model 
• Supported by the eagle-i 
ontology 
• Reducing time-consuming 
and expensive duplication 
of resources 
www.eagle-i.org
eagle-i 
Supported by National Center for Research Resources
Google meets 
Ontology-guided 
search 
eagle-i’s current 
holdings 
eagle-i Repositories: 
The same search on 
a NIF tab 
A catalog of > 70,000 human curated invisible research resources 
A set of tools and services for easy sharing of and linking of resources to articles, websites etc. 
The tools ingest Biositemaps and NIF resources.
Outline 
• Resourceome 
• Resource Inventory Projects 
• Interoperability 
• Future Plans
Resource Ontology 
eagle-i 
NIF 
BRO
Resource Information Model 
• Resource name 
• Resource description 
• URL 
• Resource type 
• Availability of documentation 
• Contact person 
• Contact person email 
• Organization
Diverse use cases require 
diverse ontologies and data sources 
Public repositories 
and 
resources 
Community ontologies 
and taxonomies 
Lab resources 
inventoried by 
eagle-i 
eagle-i ontologies 
Institutional core 
facility 
Biositemaps 
BRO ontology NIFStd ontologies 
repository repository repository
Future Plans 
Public repositories 
and 
resources 
Community ontologies 
and taxonomies 
repository 
Lab resources 
inventoried by 
eagle-i 
Institutional core 
facility 
Biositemaps
Acknowledgements 
• Mark Musen 
• Mike Becich 
• Jessica Tenenbaum 
• Fahim Imam 
• Maryann Martone 
• Chris Shaffer 
• Daniela Bourges 
• Biositemaps Consortium 
• eagle-i Consortium 
• NIF Consortium

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A Lined Data Approach to Interoperability between Biomedical Resource Inventories

  • 1. A Linked Open Data Approach to Interoperability between Biomedical Resource Inventories Trish Whetzel, Ph.D. Presenting on behalf of the Resource Coordination Group (Anita Bandrowski, Carlo Torniai, Charles Borromeo, Melissa Haendel, Jessica Tenenbaum)
  • 2. Outline • Resourceome • Resource Inventory Projects • Interoperability • Future Plans
  • 4. • Machine-readable resource associated with a website • Resources are described in terms of an information model • Supported by the Biomedical Resource Ontology • Can be discovered by search engines such as Google Biositemaps www.biositemaps.org
  • 5. Biositemaps National Centers for Biomedical Computing Clinical and Translational Science Awards www.ncbcs.org www.ctsaweb.org
  • 6. Resource Discovery System: A catalog of > 1,400 biomedical resources A set of tools and services for easy sharing of and linking of resources to articles, websites etc. The tools ingest NIF resources.
  • 7. Neuroscience Information Framework • A portal for finding and using resources • Resources are described in terms of an information model • Supported by the NIFSTD ontology • Provides simultaneous search of >30M database records, organized by www.neuinfo.org category
  • 8. Neuroscience Information Framework MT WY ID WA OR NV UT CA AZ ND SD NE CO NM TX KS OK MO AR LA MN IA WI IL IN KY TN WV VA MS AL GA SC FL MI NY PA NJ DE ME CT MD RI MA VT NH AK HI NC PR Supported by the NIH Blueprint for Neuroscience
  • 9. NIF Registry: A catalog of > 3,500 human curated databases, tools and materials A set of tools and services for easy sharing of and linking of data to articles, websites etc. The tools ingest Biositemaps and two other common resource description formats
  • 10. eagle-i • Make scientific research resources more visible via a federated network • Resources are described in terms of an information model • Supported by the eagle-i ontology • Reducing time-consuming and expensive duplication of resources www.eagle-i.org
  • 11. eagle-i Supported by National Center for Research Resources
  • 12. Google meets Ontology-guided search eagle-i’s current holdings eagle-i Repositories: The same search on a NIF tab A catalog of > 70,000 human curated invisible research resources A set of tools and services for easy sharing of and linking of resources to articles, websites etc. The tools ingest Biositemaps and NIF resources.
  • 13. Outline • Resourceome • Resource Inventory Projects • Interoperability • Future Plans
  • 15. Resource Information Model • Resource name • Resource description • URL • Resource type • Availability of documentation • Contact person • Contact person email • Organization
  • 16. Diverse use cases require diverse ontologies and data sources Public repositories and resources Community ontologies and taxonomies Lab resources inventoried by eagle-i eagle-i ontologies Institutional core facility Biositemaps BRO ontology NIFStd ontologies repository repository repository
  • 17. Future Plans Public repositories and resources Community ontologies and taxonomies repository Lab resources inventoried by eagle-i Institutional core facility Biositemaps
  • 18. Acknowledgements • Mark Musen • Mike Becich • Jessica Tenenbaum • Fahim Imam • Maryann Martone • Chris Shaffer • Daniela Bourges • Biositemaps Consortium • eagle-i Consortium • NIF Consortium