Salesforce Miami User Group Event - 1st Quarter 2024
GeneMind Introduction.pdf
1. E x p l o r e L i f e ’ s M y s t e r i e s f o r B e t t e r H e a l t h c a r e
2. Company Introduction
Specializing in the independent R&D and manufacturing of
molecular diagnosis technology platform centred on DNA
sequencing system, GeneMind Biosciences is devoted to
constructing a precision medicine ecosystem to serve human
life and health through collaboration with genetic testing
service providers and medical institutions.
GeneMind has launched the single-molecule sequencing
platform GenoCare 1600 and the high-throughput sequencing
platform GenoLab M through independent research and
innovation, and offers the “equipment-reagent-flowcell-
software” total platform solution. GeneMind is one of the
few technology companies with core upstream technology and
independent brand of gene sequencing in the world.
GenoCare 1600 is the world’s first single-molecule
sequencer that has passed medical device clinical trials.
· A high-tech enterprise with core technologies of gene
sequencing and independent intellectual property rights
High-tech
· One of the few independent brands of gene sequencers
in the world
Self-owned brand
· Single-molecule sequencer+ High-throughput sequencing
platform
Volume Production
3. E s t a b l i s h e d i n
Shenzhen, China.
July 2012
S t a r t R & D o f
single-molecule
sequencer.
S e p t e m b e r
2014
T h e f i r s t
principle prototype
of GenoCare single-
molecule sequencing
platform was born.
O c t o b e r
2015
Official completed
the GMP production
line of sequencers
and reagents.
September
2018
G e n o C a r e 1 6 0 0
single-molecule
s e q u e n c e r
successfully passed
the medical device
r e g i s t r a t i o n
inspection of NMPA.
F e b r u a r y
2019
G e n o C a r e h a s
completed medical
d e v i c e c l i n i c a l
t r i a l s , a n d t h e
p o s i t i v e a n d
negative coincidence
rate has reached
100%.
May 2020 The GenoLab high-
t h r o u g h p u t
s e q u e n c i n g
p l a t f o r m w a s
o f f i c i a l l y
launched.
O c t o b e r
2020
Approved to establish
the first provincial
a c a d e m i c i a n
workstation dedicated
to the development of
sequencer platform in
China——Guangdong
A c a d e m i c i a n
workstation.
November
2021
Milestones
4. Core Technologies
Optical System
Hardware
The high sensitivity and high
resolution optical system can
quickly complete the fluorescence
signal acquisition
Base calling algorithm
Software
Complete the output from the
original image information
acquisition to the sequencing
accurately and quickly
Different specifications are
available
Flowcell
High sensitivity; High resolution
Nucleotide analogues and
polymerases
Chemistry
The unique termination base
structure and high fidelity
polymerase provide high precision
detection
5. Products
Able to run one flow cell
alone or two flow cell
simultaneously
Dual flow cell mode
Pre-configured reagent kit
Easy-to-use
Multiple throughput types
available
Flexible
Open to mainstream NGS
libraries
Compatible
Specifications
Flowcell
Two (Able to run one flow cell alone or
two flow cell simultaneously)
Reads/Run
250 M×2(FCM);
500 M×2(FCH)
Read Length SE75、SE150、PE75、PE150
Output/Run 37~150 Gb(FCM);75~300 Gb(FCH)
Turnaround time 13~43 h(FCM);16~53 h(FCH)
Q30 Q30>85%
GenoLab M High-throughput Sequencing Platform
7. I n d e p e n d e n t R & D a n d M a n u f a c t u r i n g C a p a b i l i t y The total area of R&D and production put into use by GeneMind
is nearly 10,000 square meters. The company estalished
sequencer production factory, flowcell laboratory,GMP
production line for kits, organic synthesis laboratory, and
enzyme engineering laboratory. The mass-produced products cover
sequencing instruments, sequencing kits,and flowcell.
· Flowcell Lab
Can be produced by ourselves
· Sequencer Production Line
Annual capacity is 1000 units
· Reagent Kits Production Line
Designed as a GMP workshop to produce kits
for 2.4 million tests annually
·Enzyme Engineering Lab
Independent research and development of
core enzyme
· Organic Synthesis Lab
Able to synthesize our own nucleic acid
and fluorochrome