7. Clin manif
Depend on cause
in Hyperventilation: rapid respir rate
in Hypoglycemia
: cold wet skin
in Hyperglycemia : hot dry skin
in Hypothyroidism: weakness fatigue
in Hyperthyroidism : restlessness
in cerebr vasc acc: sudden loss of consc
8. management
1-Recognize
2- terminate dental procedure
3-P-----depend on cause
supine position is accepitable…….
in diabetic & thyroid dis--- upright
in cerebrovasc acc---- can upright to dec bl pr
3- A
B
C
4-definitive care
m- monitor vital signs
m- manage signs & symptom
d-defin tt depend on cause
9.
10. DIABETES MELLITUS [dm.]
Definition
a disorder of glucose metabolism --
hyperglycemia due to decr insulin secretion
or decr its activity or both
Normal glucose level
80----100 mg /100ml blood
decr 50 mg------------hypoglyc in adults
decr 40 mg-----------hypoglyc in children
15. Affecting large bl vessels-----arteriosclerosis
Affecting small bl vessels--microangiopathy
Affecting interstit tissue…..
infections
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27. Predisposing factors
Genetic factor
if both parent --------100%offsprings
Disorders destroying islets of langerhans
Other endocrine dysfunctions
corticost ttt ----iatrogenic diabetes
28. Classification of diabetes
Depending on age
adult onset DM
juvenile onset DM
Depending on insulin injections
insulin dependent DM
non insulin dependent DM
NOW we have these types
29.
30. Type I DM
Type II DM
Impaired glucose tolerance I G T
Impaired fasting glucose I F G
Gestational diabetes
31. Type I, juvenile, IDDM
Genetically determined
8%
Usually start in young
There is no insulin in pat blood ie
[ insulinopenic]
glucagon is high
pancreatic B-cells are non responsive
32. Genetically determined
8%
Usually start in young
There is no insulin in pat blood ie
[ insulinopenic]
glucagon is high
pancreatic B-cells are non
responsive
33. GENETICALLY
human lymphocytic antigens on the
lymphocytes determined by chromosome
6 are impaired
Immunologically
may autoimmune response as there
are antibodies…
Other causes infect, drugs
34. Type II, adult, NIDDM
milder
80 %
Usually start in adults
There are enough insulin [ to avoid
ketoacidosis]
usually don’t need exogenous insulin
35.
May be duo to lack of insulin receptors in
peripheral tissues
is divided into
Non obese type
Obese type
37. Clinical manifestations
D M ----- may be presented as
hyperglycemia
or hypoglycemia
NB hypoglycemia is more dangerous
D M ----- may be presented as
one or more of its complications
38.
In hyperglycemia
There is syndrome of poly
polyurea, polydipsia ,polyphagia
,blurred vision ,pruritus….
Start by nocturnal enuresis with loss of w --coma
Other S/S…..
40.
In hypoglycemia
In Early –CNS : hunger, nausea, hyperactive
In Moderate--- adrenaline is released...>
sweating ,bizarre behavioral patterns
In severe: unconsc, seizures ,hypotention
&hypothermia
Acute complications are common
42. Control of DM
Self monitoring
Diet control
Physical activity
Oral hypoglycemic drugs
a)sulfonyureas
tolbutamide
Glyburide
b)biguanide metformin
Insulin treatment
43. Prevention
Preliminary patient evaluation
Physical exam
DENTAL observations
-if any doubt--- physician
Type II can tolerate dental care
Type I should be cared
Observe ttt & complications
Adjust dose of local anesth, insulin
44. Diabetic patients can tolerate
hyperglycemia more than hypoglycemia
So after extensive dental procedures
type I DM ---check blood
glucose level in the next few days….
Antibiotic cover is important
45. management
I- recognition
Sign & sy of hypoglycemia
early: hunger ,nausea, Weakness & dizziness
moderate :[adren rel],hot moist Pale skin
late : anxiety , Headache
Altered consc
Sign & sy of hyperglycemia…..poly syndrome…
blood glucose > 250 [non fasting]
Acidosis ph < 7.3
Dry [loss of water],warm skin
Abnormal respir [ Kussmaul’s ]
Rapid weak pulse
Altered consc
46. D/D hypoglycemia &hyperglycemia
In hypoglycemia
onset : rapid [ min]
Skin
: cold & wet
Breath : no odour
In hyperglycemia
onset
: slow [ hours & days ]
Skin
: hot & dry
Breath : acetone
If still in doubt----------apply PABC till medical assist
DM patient with imp consc should be managed as
having hypoglycemia until proved otherwise
47. Manag of hypogly a-consc
1-recognition of hypoglycemia
2-terminate dent proc
3-p
4-A, B,C
5-definitive care
oral CHO
orange juice
6- recovery
observe for at least 1h
48. Manag of hypogly b-unconsc
1- no time for recognition of hypoglycemia
2-terminate dent proc
3-p
4-A, B,C
5-definitive care
summoning of medical assistance
IV CHO
50% dextrose
1mg glucagon
.5mg epinephrine
6- recovery
oral CHO after recovery
49. Manag of hypergly a-consc
1-recognition of hyperglycemia
2-avoid any dental pro & terminate any
one
50. Manag of hypergly b-unconsc
1-R
2-terminate dent proc
3-p
4-A, B,C
7-definitive care
medical assistance
IV CHO
5% , 5% , 5% . 5% . 5% dextrose
?? insulin in emergency
give O
8- transport to hospital