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Cord Blood and Cord Tissue Stem Cell Banking




Discover the benefits of banking
your newborn’s stem cells.




                                      Find Us On

     Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking




                         Your baby’s umbilical cord is a valuable
                         source of stem cells that can potentially
                         treat dozens of diseases.1 Collecting and
                         preserving these cells is a simple, painless
                         procedure that can take place after a
                         vaginal or cesarean birth.

                         Cord blood and cord tissue stem cell
                         banking simply preserves what would
                         otherwise be discarded.




                                 Find Us On

Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking




                          Cord Blood               Surrounding Cord Tissue
           A rich source of HEMATOPOIETIC stem    An additional and abundant source of
           cells (HSCs) and MESENCHYMAL stem      MSCs
           cells (MSCs)

           Cord blood stem cells are being        With a greater number and variety
           used to treat nearly 80 life-          of stem cells, patients can
           threatening diseases, including        significantly increase their chances
           emerging areas like cerebral palsy     of success in a transplant, and
           and type 1 diabetes.2                  benefit from the potential to treat
                                                  additional disorders. 3-9

                                                  NOTE: Medical treatments using family banked cord
                                                  tissue are not available today; there is no guarantee
                                                  that therapies will be developed in the future.




2. Most of these nearly 80 diseases are
genetic disorders, which would be treated                                                                 Find Us On
using cord blood from a sibling. Emerging
treatments today are performed with the
baby’s own cord blood.                      Viacord Blog          www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking




               If a stem cell transplant is needed, there is an increased chance
               of finding an acceptable match within your own family. 10


               Transplants using cord blood from a family member are proven
               to be more successful than transplants using cord blood from a
               non-relative. 11


               Access to emerging treatments such as those focused on
               cerebral palsy and Type 1 Diabetes, require a patient to use his
               or her own cord blood stem cells. 12-13




                                             Find Us On

Viacord Blog       www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking


                ViaCord® offers families two options:
Cord Blood Banking OR Cord Blood + Cord Tissue Stem Cell Banking


            When you enroll with ViaCord® you’ll receive
            a collection kit that contains everything your
            doctor will need for a successful collection.




                                               Find Us On

              Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking



The collection process is simple. After birth, the umbilical cord is clamped and cut,
as it would be even if the stem cells were not being saved:



                                                  Cord Blood Collection
                                                  The blood remaining in the umbilical cord is
                                                  extracted and flows into ViaCord’s ® collection
                                                  bag by gravity until it stops. The actual
                                                  collection typically takes three to five minutes.

                                                  Cord Tissue Collection
                                                  If you have chosen to preserve the stem
                                                  cells from the surrounding cord tissue the
                                                  OB/GYN will place the tissue in the sterile
                                                  specimen cup provided by ViaCord®.




                                                           Find Us On

                          Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking


Once your newborn’s stem cells are collected ViaCord® will
arrange for a medical courier to come to your bed side, pick
up your collection kit, and facilitate transport to ViaCord’s®
processing facility.

ViaCord® will processes your newborn’s stem cells and place
them in high-quality, secure, long-term storage.




                                         Find Us On

        Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking


Over 250,000 families have entrusted their cord blood to ViaCord® 14


                                            Cord blood banking is a natural way to
                                            protect your baby or a sibling. Since the
                                            first cord blood stem cell transplant in
                                            1988, over 20,000 have been performed
                                            worldwide.15

                                            Families who bank enjoy the peace of
                                            mind of knowing that their baby’s cord
                                            blood is available should the need for a
                                            medical transplant ever arise.




                                                   Find Us On

                  Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking




          Storing newborn stem cells with ViaCord is a
         unique investment in the health of your family.


talk to a specialist at 1.866.668.4895 or visit www.viacord.com
                         We’re here 24/7!




                                               Find Us On

              Viacord Blog   www.viacord.com
Cord Blood and Cord Tissue Stem Cell Banking


References
1.    Data on file. PerkinElmer, Inc.
2.    Most of these nearly 80 diseases are genetic disorders, which would be treated using cord blood from a sibling. Emerging treatments today are
      performed with the baby’s own cord blood.
3.    Fu YS, Cheng YC, Lin MY, et al. Conversion of human umbilical cord mesenchymal stem cells in Wharton’s jelly to dopaminergic neurons in vitro:
      potential therapeutic application for Parkinsonism. Stem Cells. 2006;24(1):115-124. Epub 2005 Aug 11.
4.    Liu Y, Mu R, Wang S, et al. Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis.
      Arthritis Res Ther. 2010;12(6):R210.
5.    Ding DC, Shyu WC, Chiang MF, et al. Enhancement of neuroplasticity through upregulation of b1-integrin in human umbilical cord-derived stromal
      cell implanted stroke model. Neurobiol Dis. 2007;27(3):339-353. Epub 2007 Jun 18.
6.    Anzalone R, Lo Iacono M, Loria T, et al. Wharton’s jelly mesenchymal stem cells as candidates for beta cells regeneration: extending the
      differentiative and immunomodulatory benefits of adult mesenchymal stem cells for the treatment of type 1 diabetes. Stem Cell Rev. 2010 Oct 23.
      [Epub ahead of print.]
7.    Tsai PC, Fu TW, Chen YM, et al. The therapeutic potential of human umbilical mesenchymal stem cells from Wharton’s jelly in the treatment of rat
      liver fibrosis. Liver Transpl. 2009;15(5):484-495.
8.    Maurya DK, Doi C, Kawabata A, et al. Therapy with un-engineered naïve rat umbilical cord matrix stem cells markedly inhibits growth of murine
      lung adenocarcinoma. BMC Cancer. 2010;10:590.
9.    Wang L, Tran I, Seshareddy K, et al. A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived
      mesenchymal stromal cells for cartilage tissue engineering . Tissue Eng. 2009;15(8)(pt A):2259-2266.
10.   Beatty PG, Boucher KM, Mori M, Milford EL. Probability of finding HLA mismatched related or unrelated marrow or cord blood donors. Hum
      Immunol. 2000;61(8):834-840. Based on a 3/6 human leukocyte antigen
11.   Gluckman, et al., New England Journal of Medicine 1997, pp. 373-381.
12.   National Institutes of Health, ClinicalTrials.gov. Umbilical cord blood infusion to treat type 1 diabetes.
      http://clinicaltrials.gov/ct2/show/NCT00305344?term=umbilical+cord+blood+diabetes&rank=1. Accessed March 24, 2011.
13.   National Institutes of Health, ClinicalTrials.gov. A randomized study of autologous umbilical cord blood reinfusion in children with cerebral palsy .
      http://clinicaltrials.gov/ct2/show/NCT1147653?term=kurtzberg&rank=
14.   Data on file. PerkinElmer, Inc.
15.   Broxmeyer, “Cell Stem Cell 6”. 8 January 2010. Pg. 21-24

Disclaimer

There is no guarantee that cord blood will provide a cure or be a suitable treatment option for that child or a sibling. Transplant success is dependent
upon many factors including disease type, patient condition, recipient-donor relationship and matching, and more. Use will be determined by a
physician. Cord blood use for emerging treatments is experimental. Medical treatments using family banked cord tissue are not available today; there
is no guarantee that therapies will be developed in the future




                                                                                                 Find Us On

                                       Viacord Blog             www.viacord.com

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ViaCord Slideshow

  • 1. Cord Blood and Cord Tissue Stem Cell Banking Discover the benefits of banking your newborn’s stem cells. Find Us On Viacord Blog www.viacord.com
  • 2. Cord Blood and Cord Tissue Stem Cell Banking Your baby’s umbilical cord is a valuable source of stem cells that can potentially treat dozens of diseases.1 Collecting and preserving these cells is a simple, painless procedure that can take place after a vaginal or cesarean birth. Cord blood and cord tissue stem cell banking simply preserves what would otherwise be discarded. Find Us On Viacord Blog www.viacord.com
  • 3. Cord Blood and Cord Tissue Stem Cell Banking Cord Blood Surrounding Cord Tissue A rich source of HEMATOPOIETIC stem An additional and abundant source of cells (HSCs) and MESENCHYMAL stem MSCs cells (MSCs) Cord blood stem cells are being With a greater number and variety used to treat nearly 80 life- of stem cells, patients can threatening diseases, including significantly increase their chances emerging areas like cerebral palsy of success in a transplant, and and type 1 diabetes.2 benefit from the potential to treat additional disorders. 3-9 NOTE: Medical treatments using family banked cord tissue are not available today; there is no guarantee that therapies will be developed in the future. 2. Most of these nearly 80 diseases are genetic disorders, which would be treated Find Us On using cord blood from a sibling. Emerging treatments today are performed with the baby’s own cord blood. Viacord Blog www.viacord.com
  • 4. Cord Blood and Cord Tissue Stem Cell Banking If a stem cell transplant is needed, there is an increased chance of finding an acceptable match within your own family. 10 Transplants using cord blood from a family member are proven to be more successful than transplants using cord blood from a non-relative. 11 Access to emerging treatments such as those focused on cerebral palsy and Type 1 Diabetes, require a patient to use his or her own cord blood stem cells. 12-13 Find Us On Viacord Blog www.viacord.com
  • 5. Cord Blood and Cord Tissue Stem Cell Banking ViaCord® offers families two options: Cord Blood Banking OR Cord Blood + Cord Tissue Stem Cell Banking When you enroll with ViaCord® you’ll receive a collection kit that contains everything your doctor will need for a successful collection. Find Us On Viacord Blog www.viacord.com
  • 6. Cord Blood and Cord Tissue Stem Cell Banking The collection process is simple. After birth, the umbilical cord is clamped and cut, as it would be even if the stem cells were not being saved: Cord Blood Collection The blood remaining in the umbilical cord is extracted and flows into ViaCord’s ® collection bag by gravity until it stops. The actual collection typically takes three to five minutes. Cord Tissue Collection If you have chosen to preserve the stem cells from the surrounding cord tissue the OB/GYN will place the tissue in the sterile specimen cup provided by ViaCord®. Find Us On Viacord Blog www.viacord.com
  • 7. Cord Blood and Cord Tissue Stem Cell Banking Once your newborn’s stem cells are collected ViaCord® will arrange for a medical courier to come to your bed side, pick up your collection kit, and facilitate transport to ViaCord’s® processing facility. ViaCord® will processes your newborn’s stem cells and place them in high-quality, secure, long-term storage. Find Us On Viacord Blog www.viacord.com
  • 8. Cord Blood and Cord Tissue Stem Cell Banking Over 250,000 families have entrusted their cord blood to ViaCord® 14 Cord blood banking is a natural way to protect your baby or a sibling. Since the first cord blood stem cell transplant in 1988, over 20,000 have been performed worldwide.15 Families who bank enjoy the peace of mind of knowing that their baby’s cord blood is available should the need for a medical transplant ever arise. Find Us On Viacord Blog www.viacord.com
  • 9. Cord Blood and Cord Tissue Stem Cell Banking Storing newborn stem cells with ViaCord is a unique investment in the health of your family. talk to a specialist at 1.866.668.4895 or visit www.viacord.com We’re here 24/7! Find Us On Viacord Blog www.viacord.com
  • 10. Cord Blood and Cord Tissue Stem Cell Banking References 1. Data on file. PerkinElmer, Inc. 2. Most of these nearly 80 diseases are genetic disorders, which would be treated using cord blood from a sibling. Emerging treatments today are performed with the baby’s own cord blood. 3. Fu YS, Cheng YC, Lin MY, et al. Conversion of human umbilical cord mesenchymal stem cells in Wharton’s jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism. Stem Cells. 2006;24(1):115-124. Epub 2005 Aug 11. 4. Liu Y, Mu R, Wang S, et al. Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. Arthritis Res Ther. 2010;12(6):R210. 5. Ding DC, Shyu WC, Chiang MF, et al. Enhancement of neuroplasticity through upregulation of b1-integrin in human umbilical cord-derived stromal cell implanted stroke model. Neurobiol Dis. 2007;27(3):339-353. Epub 2007 Jun 18. 6. Anzalone R, Lo Iacono M, Loria T, et al. Wharton’s jelly mesenchymal stem cells as candidates for beta cells regeneration: extending the differentiative and immunomodulatory benefits of adult mesenchymal stem cells for the treatment of type 1 diabetes. Stem Cell Rev. 2010 Oct 23. [Epub ahead of print.] 7. Tsai PC, Fu TW, Chen YM, et al. The therapeutic potential of human umbilical mesenchymal stem cells from Wharton’s jelly in the treatment of rat liver fibrosis. Liver Transpl. 2009;15(5):484-495. 8. Maurya DK, Doi C, Kawabata A, et al. Therapy with un-engineered naïve rat umbilical cord matrix stem cells markedly inhibits growth of murine lung adenocarcinoma. BMC Cancer. 2010;10:590. 9. Wang L, Tran I, Seshareddy K, et al. A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering . Tissue Eng. 2009;15(8)(pt A):2259-2266. 10. Beatty PG, Boucher KM, Mori M, Milford EL. Probability of finding HLA mismatched related or unrelated marrow or cord blood donors. Hum Immunol. 2000;61(8):834-840. Based on a 3/6 human leukocyte antigen 11. Gluckman, et al., New England Journal of Medicine 1997, pp. 373-381. 12. National Institutes of Health, ClinicalTrials.gov. Umbilical cord blood infusion to treat type 1 diabetes. http://clinicaltrials.gov/ct2/show/NCT00305344?term=umbilical+cord+blood+diabetes&rank=1. Accessed March 24, 2011. 13. National Institutes of Health, ClinicalTrials.gov. A randomized study of autologous umbilical cord blood reinfusion in children with cerebral palsy . http://clinicaltrials.gov/ct2/show/NCT1147653?term=kurtzberg&rank= 14. Data on file. PerkinElmer, Inc. 15. Broxmeyer, “Cell Stem Cell 6”. 8 January 2010. Pg. 21-24 Disclaimer There is no guarantee that cord blood will provide a cure or be a suitable treatment option for that child or a sibling. Transplant success is dependent upon many factors including disease type, patient condition, recipient-donor relationship and matching, and more. Use will be determined by a physician. Cord blood use for emerging treatments is experimental. Medical treatments using family banked cord tissue are not available today; there is no guarantee that therapies will be developed in the future Find Us On Viacord Blog www.viacord.com