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Single-Use Bioreactors for Pharma:
World Market 2013-2023
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Contents
1.1 Single-Use Bioreactors: Market Review
1.2 Aims, Scope and Format of the Report
1.3 Research and Analysis Methods
2.1 Introduction
2.1.1 Historical Perspective: A Brief Overview
2.2 The Wave Bioreactor
2.3 Current Single-Use Systems on the Market
2.3.1 Stirred Flexible Disposable Bioreactors
2.3.2 Non-Stirred Flexible Disposable Bioreactors
2.3.3 Stirred Rigid Disposable Bioreactors
2.3.4 Non-Stirred Rigid Disposable Bioreactors
2.3.5 Fixed-Bed Bioreactors
2.4 Construction Material for Single-Use Bioreactors
2.5 Measurement and Control for Single-Use Bioreactors
2.6 Main Applications of Disposable Bioreactors
3.1 The World Single-Use Bioreactors Market in 2012
3.2 Growing Market for Single-Use Bioreactor Systems
3.2.1 Sales Forecast for Overall Single-Use Bioreactors Market, 2012-2017
3.2.2 Sales Forecast for Overall Single-Use Bioreactors Market, 2018-2023
3.3 Breakdown of the Global Single-Use Bioreactors Market
3. The World Market for Single-Use Bioreactors, 2013-2023
2. Single-Use Bioreactor Technologies: an Introduction
1. Executive Summary
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Contents
3.3.1 Sales Forecast for Single-Use Bioreactors: Hardware Modules/Systems, 2012-2017
3.3.2 Sales Forecast for Single-Use Bioreactors: Hardware Modules/Systems, 2018-2023
3.3.3 Sales Forecast for Single-Use Bioreactors: Disposables and Accessories, 2012-2017
3.3.4 Sales Forecast for Single-Use Bioreactors: Disposables and Accessories, 2018-2023
3.4 Leading National Markets for Single-Use Bioreactors Technology, 2013-2023
3.4.1 The US Market for Single-Use Bioreactors Technology, 2013-2023
3.4.2 The Japanese Single-Use Bioreactors Technology Market, 2013-2023
3.4.3 The Leading European Single-Use Bioreactors Technology Markets, 2013-2023
3.4.4 Emerging National Markets for Single-Use Bioreactor Technology
3.4.5 The Chinese Single-Use Bioreactors Technology Market, 2013-2023
3.4.6 The Indian Single-Use Bioreactors Technology Market, 2013-2023
4.1 Introduction
4.2 Xcellerex
4.2.1 Overview
4.2.2 Products, Platforms & Technology
4.2.2.1 FlexFactory Biomanufacturing Platform
4.2.2.2 XDR Single-Use Bioreactors
4.2.2.3 XDM QUAD Single-Use Mixing Systems
4.2.2.4 XDA Disposable Assembly
4.2.2.5 Process Development Services
4.2.2.6 FlexFactory Services
4.2.3 Finances
4.2.4 Xcellerex Milestones & Recent Developments
4.2.5 GreenVax Selects Xcellerex XDR Single-Use Bioreactors for New Vaccine and
Biotherapeutics Programme
4.2.6 Future Outlook and Commercial Strategy
4. Leading Companies in the Market
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Contents
4.2.7 GE Healthcare Completes Acquisition of Xcellerex
4.3 Cellexus Limited
4.3.1 Overview
4.3.2 Global Presence
4.3.3 Products
4.3.4 CellexusBag
4.3.5 CellMaker PLUS
4.3.5.1 CellMaker PLUS Components
4.3.5.2 CellMaker PLUS Dimensions and Specifications
4.3.6 The Cellexus Oxygenator
4.3.6.1 Cellexus Oxygenator: Main Features and Benefits
4.3.6.2 Cellexus Oxygenator Dimensions and Specifications
4.3.7 Single-Use Bioreactor Cell Culture Control Instrumentation
4.3.8 Cellexus Airlift Proprietary Technologies
4.3.9 Single-Use, Non-Penetrative Sensor Technology
4.3.10 Future Outlook
4.4 Sartorius Stedim Biotech
4.4.1 Overview
4.4.2 International Presence
4.4.3 Services and Products
4.4.4 Revenues
4.4.5 Future Outlook
4.5 Thermo Scientific Hyclone
4.5.1 Overview
4.5.2 Global Presence
4.5.3 Thermo Scientific HyClone Products
4.5.4 Thermo Scientific HyClone (SUB): A Disposable Alternative to Conventional Stirred Tank
Bioreactors
4.5.5 Hyclone SUB Components
4.5.6 Future Outlook
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Contents
4.6 GE Healthcare
4.6.1 Overview
4.6.2 Global Presence
4.6.3 Bioreactor Products
4.6.4 WAVE Bioreactor Systems
4.6.5 Cell Culture Products
4.6.6 Mixing Products
4.6.7 Fluid Transfer Products
4.6.8 M&A Activity
4.6.9 Future Outlook
4.7 PBS Biotech
4.7.1 Overview
4.7.2 Global Footprint
4.7.3 PBS Design and Air Wheel Mixing System
4.7.4 Applications & Processes
4.7.5 PBS Specialties
4.7.6 Main Products
4.7.7 Company Highlights
4.7.8 Future Outlook
4.8 ATMI LifeSciences
4.8.1 Overview
4.8.2 Global Footprint
4.8.3 ATMI Specialties
4.8.4 Main Bioreactor Products
4.8.4.1 iCELLis
4.8.4.2 Nucleo Single-Use Bioreactor
4.8.4.3 PadReactor Single-Use Bioreactor
4.8.4.4 Xpansion Bioreactor
4.8.4.5 Bag Conversion
4.8.5 Other Disposable Products
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Contents
4.8.6 Financial Performance
4.8.7 Future Outlook
5.1 Introduction
5.2 Commercial Drivers of the Single-Use Bioreactors Market
5.2.1 Cost Reduction: A Major Driver in Disposable Bioreactors Market
5.2.2 Comparison of Single-Use and Traditional Manufacturing Systems
5.3 Commercial Restraints for the Single-Use Bioreactors Market
5.3.1 Disposable Bioreactors and their Impact on the Environment
5.3.2 Options for Waste Disposal for Bioreactors
5.3.3 Lack of Defined ‘Leachable and Extractable’ Standards Causing Concern
5.3.4 Disposable Bioreactors Unlikely to Replace Traditional Manufacturing Systems Entirely
5.3.5 Scalability and Size Limitations Still Concern Biomanufacturers
5.4 Challenges Facing the Single-Use Bioreactor Technology Industry and Market
5.4.1 Bottlenecks in Downstream Processing
5.5 Summary
6.1 Interview with Mr Christian Julien, Business Development Manager, Meissner Filtration
Products, Inc. Camarillo, California, USA
6.1.1 On Current Market for Single-Use Bioreactors
6.1.2 On Key Unmet Needs in the Market for Single-Use Bioreactors
6.1.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology
6.1.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.1.5 On Advantages of Disposable Technology
6.1.6 On Major Drawbacks of Single-Use Bioreactor Technology
6. Research Interviews from Our Survey
5. Qualitative Analysis of the Single-Use Bioreactor Technology Market
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Contents
6.1.7 On New Developments in the Single-Use Bioreactors Sector
6.1.8 On Pipeline Technology in the Single-Use Bioreactors Market
6.2 Interview with Dr Karl G. Schick, PhD, Vice President of Research & Development, SciLog
Inc., Madison, Wisconsin, USA
6.2.1 On Current Market for Single-Use Bioreactors
6.2.2 On Key Unmet Needs in the Market for Single-Use Bioreactors
6.2.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology
6.2.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.2.5 On Advantages of Disposable Technology
6.2.6 On Major Drawbacks of Single-Use Bioreactor Technology
6.2.7 On New Developments in the Single-Use Bioreactors Sector
6.2.8 On Pipeline Technology in the Single-Use Bioreactors Market
6.3 Interview with Professor Pamela J. Weathers, PhD, Biology & Biotechnology Dept.,
Worcester Polytechnic Institute, Worcester, MA, USA
6.3.1 On Current Market for Single-Use Bioreactors
6.3.2 On Key Unmet Needs in the Market for Single-Use Bioreactors
6.3.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology
6.3.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.3.5 On Advantages of Disposable Technology
6.3.6 On Major Drawbacks of Single-Use Bioreactor Technology
6.3.7 On New Developments in the Single-Use Bioreactors Sector
6.3.8 On Pipeline Technology in the Single-Use Bioreactors Market
6.4 Interview with Professor Milen Georgiev, PhD, Institute of Microbiology, Bulgarian Academy
of Sciences, Plovdiv, Bulgaria
6.4.1 On Current Market for Single-Use Bioreactors
6.4.2 On Key Unmet Needs in the Market for Single-Use Bioreactors
6.4.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology
6.4.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.4.5 On Advantages of Disposable Technology
6.4.6 On Major Drawbacks of Single-Use Bioreactor Technology
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Contents
6.4.7 On New Developments in the Single-Use Bioreactors Sector
6.5 Interview with James B. Schultz, Vice President, Sales & Marketing, PBS Biotech, Camino
Ranchero, Camarillo, CA, USA
6.5.1 On Current Market for Single-Use Bioreactors
6.5.2 On Key Unmet Needs in the Market for Single-Use Bioreactors
6.5.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology
6.5.4 On Advantages of Disposable Technology
6.5.5 On Major Drawbacks of Single-Use Bioreactor Technology
6.5.6 On New Developments in the Single-Use Bioreactors Sector
6.5.7 On Technologies in Pipeline for the Single-Use Bioreactors Sector
6.6 Interview with Dr Tibor Anderlei, Head of Science and Business Development, Adolf Kühner,
Dinkelbergstr, Birsfelden, Basel, Switzerland
6.6.1 On Current Market for Single-Use Bioreactors
6.6.2 On Key Unmet Needs in the Market for Single-Use Bioreactors
6.6.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology
6.6.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.6.5 On Advantages of Disposable Technology
6.6.6 On Major Drawbacks of Single-Use Bioreactor Technology
6.6.7 On Technologies in the Pipeline for the Single-Use Bioreactors Sector
6.7 Interview with Dr Jean Paul Ducos, Nestlé R&D Centre Tours, France
6.7.1 On Plant Propagation R&D and Areas of Focus in Single-Use Bioreactor Technology
6.7.2 On Main Challenges in Plant Propagation Research and Single-Use Bioreactor
Technology
6.7.3 On Advantages of Single-Use Bioreactor Technology for Plant Propagation
6.7.4 On Drawbacks of Single-Use Bioreactor Technology in Plant Propagation
6.7.5 On New Developments in Single-Use Bioreactors Sector
6.7.6 On Pipeline Technology in Single-Use Bioreactors Market
6.8 Interview with William Whitford, Sr. Technical Market Manager, Thermo Scientific Cell
Culture & BioProcessing, Thermo Fisher Scientific, Utah, USA
6.8.1 On Current SUB Market
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Contents
6.8.2 On Key Unmet Needs in the Single-Use Bioreactors Market
6.8.3 On Key Areas of Focus in Single-Use Bioreactor Technology
6.8.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.8.5 On Advantages of Disposable Technology
6.8.6 On Major Drawbacks of Single-Use Bioreactor Technology
6.8.7 On R&D and SUB Sector
6.8.8 On Pipeline Products and Technologies in the Single-Use Bioreactors Sector
6.9 Dr. Gerhard Greller, R&D Director Upstream Technology, Sartorius Stedim Biotech,
Goettingen, Germany
6.9.1 On Current SUB Market
6.9.2 On Key Unmet Needs in the Single-Use Bioreactors Market
6.9.3 On Key Areas of Focus in Single-Use Bioreactor Technology
6.9.4 On Main Challenges Facing the Single-Use Bioreactors Market
6.9.5 On Advantages of Disposable Technology
6.9.6 On Major Drawbacks of Single-Use Bioreactor Technology
6.9.7 On R&D and SUB Sector
6.9.8 On Pipeline Products and Technologies in the Single-Use Bioreactors Sector
6.10 Overview of the Biotech Industry in 2013: Interview with Ronald A. Rader, President of
Biotechnology Information Institute (BII)
6.10.1 Steady Growth, but a Dearth of New Blockbusters
6.10.2 The Price of Biological Drugs
6.10.3 Biosimilars to Outnumber Innovator Products
6.10.4 ‘Differentiated Biologics’: Biosimilars Vs Bio-Betters
6.10.5 Changing of the Guard: Can New Classes of Biopharmaceuticals Transform the
Market?
6.10.6 Big Pharma and the Biotechs
6.10.7 Bundled Payments and Bulked-up Portfolios, and Other Reasons Why Every Major
Player Will Get Involved in Biosimilars
6.10.8 Modular Bioprocessing: The Next Revolution?
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Contents
7.1 Overview
7.2 Prominent Companies in the Market
7.3 Commercial Drivers of the Single-Use Bioreactors Market
7.4 Future Outlook and Concluding Remarks
7. Conclusions: Single-Use Bioreactor Systems – a Growth Market
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Contents
Table 2.1 A Selection of Single-Use Bioreactor Systems on the Market, 2013
Table 3.1 World Single-Use Bioreactors Market Forecast: Revenues ($m), AGR (%), CAGR (%),
2012-2017
Table 3.2 World Single-Use Bioreactors Market Forecast: Revenues ($m), AGR (%), CAGR (%),
2018-2023
Table 3.3 World Single-Use Bioreactors: Market Hardware Modules/Systems Revenue Forecast
($m), AGR (%), CAGR (%), 2012-2017
Table 3.4 World Single-Use Bioreactors Market: Hardware Modules/Systems Revenue Forecast
($m), AGR (%), CAGR (%), 2018-2023
Table 3.5 World Single-Use Bioreactors Market: Disposables and Accessories Revenue Forecast
($m), AGR (%), CAGR (%), 2012-2017
Table 3.6 World Single-Use Bioreactors Market: Disposables and Accessories Revenue Forecast
($m), AGR (%), CAGR (%), 2018-2023
Table 3.7 Single-Use Bioreactors Submarket Revenue Forecast ($m), AGR (%), CAGR (%), 2012-
2017
Table 3.8 Single-Use Bioreactors Submarket Revenue Forecast ($m), AGR (%), CAGR (%), 2018-
2023
Table 3.9 The US Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%),
CAGR (%), 2012-2017
Table 3.10 The US Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%),
CAGR (%), 2018-2023
Table 3.11 The Japanese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR
(%), CAGR (%), 2012-2017
Table 3.12 The Japanese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR
(%), CAGR (%), 2018-2023
Table 3.13 The EU 5 Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR
(%), CAGR (%), 2012-2017
List of Tables
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Contents
Table 3.14 The EU 5 Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR
(%), CAGR (%), 2018-2023
Table 3.15 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR
(%), CAGR (%), 2012-2017
Table 3.16 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR
(%), CAGR (%), 2018-2023
Table 3.17 The Indian Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR
(%), CAGR (%), 2012-2017
Table 3.18 The Indian Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR
(%), CAGR (%), 2018-2023
Table 3.19 Single-Use Bioreactors: Leading National Markets Revenue Forecast ($m), AGR (%),
CAGR (%), 2012-2017
Table 3.20 Single-Use Bioreactors: Leading National Market Revenue Forecast ($m), AGR (%),
CAGR (%), 2018-2023
Table 4.1 Single-Use Bioreactors: Manufacturers and Suppliers, 2013
Table 4.2 CellMaker PLUS Component Dimensions and Specifications, 2013
Table 4.3 Cellexus Oxygenator Dimensions and Specifications, 2013
Table 5.1 SWOT Analysis: Strengths and Weaknesses of the World Single-Use Bioreactors
Market, 2013-2023
Table 5.2 SWOT Analysis: Opportunities and Threats in the World Single-Use Bioreactors
Market, 2013-2023
Table 5.3 Comparison of Disposal Options for Single-Use Bioreactor System, 2013
Table 7.1 Single-Use Bioreactors Market: World Revenue Forecast ($m), AGR (%), CAGR (%) by
Sector in 2012, 2014, 2017, 2020 and 2023
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Contents
Figure 2.1 Main Applications and Classes of Disposable Bioreactors, 2013
Figure 3.1 World Single-Use Bioreactors Market Revenue Forecast ($m), 2012-2017
Figure 3.2 World Single-Use Bioreactors Market Revenue Forecast ($m), 2018-2023
Figure 3.3 World Single-Use Bioreactors Market: Hardware Modules/ Systems Revenue ($m)
Forecast, 2012-2017
Figure 3.4 World Single-Use Bioreactors Market: Hardware Modules/Systems Revenue ($m)
Forecast, 2018-2023
Figure 3.5 World Single-Use Bioreactors Market: Disposables and Accessories Revenue ($m)
Forecast, 2012-2017
Figure 3.6 World Single-Use Bioreactors Market: Disposables & Accessories Revenue ($m)
Forecast, 2018-2023
Figure 3.7 Single-Use Bioreactors: Submarket Revenue ($m) Forecasts, 2012-2023
Figure 3.8 The US Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023
Figure 3.9 Japan: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023
Figure 3.10 EU 5 Countries: Single-Use Bioreactors National Market Revenue ($m) Forecasts,
2012-2023
Figure 3.11 China: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023
Figure 3.12 India: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023
Figure 3.13 US, Japan and Total Worldwide Single-Use Bioreactors Markets: Revenue ($m)
Forecasts, 2012-2023
Figure 3.14 EU 5 and Other Leading Single-Use Bioreactors National Markets: Revenue ($m)
Forecasts, 2012-2023
Figure 3.15 Single-Use Bioreactors: National Market Revenue Shares (%), 2012
Figure 3.16 Single-Use Bioreactors: National Market Revenue Shares (%), 2017
Figure 3.17 Single-Use Bioreactors: National Market Revenue Shares (%), 2020
Figure 3.18 Single-Use Bioreactors: National Market Revenue Shares (%), 2023
Figure 4.1 Xcellerex: Opportunities and Threats, 2013-2023
Figure 4.2 Cellexus: Opportunities and Threats, 2013-2023
List of Figures
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Contents
Figure 4.3 Sartorius Stedim Biotech: Opportunities and Threats, 2013-2023
Figure 4.4 Thermo Scientific Hyclone: Opportunities and Threats, 2013-2023
Figure 4.5 GE Healthcare: Opportunities and Threats, 2013-2023
Figure 4.6 PBS Biotech: Opportunities and Threats, 2013-2023
Figure 4.7 ATMI: Opportunities and Threats, 2013-2023
Figure 5.1 Estimated Cost Savings of Single-Use Bioreactors in Comparison with Stainless Steel
Systems, 2013
Figure 5.2 Disposal Route Taken by Companies for Single-Use Plastic Materials, 2009
Figure 7.1 The Single-Use Bioreactors Market: Market Shares (%) in The Worldwide Single-Use
Systems Market, 2012
Figure 7.2 Single-Use Bioreactors Market: World Revenue Forecast ($m) by Segment in 2012,
2014, 2017, 2020 and 2023
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Contents
3M Occupational Health & Environmental Safety
A Daigger & Company
ABEC
Adolf Kühner
Aeronex
Air Products and Chemicals
Alconox
American Health & Safety
American Instrument Exchange
Amgen
AmProtein
Anachemia Science
Applikon Biotechnology
Artelis
Artisan Industries Inc.
Ashland Chemical Co.
ATL (Ad Tape & Label)
ATMI
Bayer Technology
Bel-Art Products
Bellco Glass
Bioengineering AG
BioProcess Systems Alliance (BPSA)
Bio-Recovery
Biotechnology Information Institute (BII)
Bosch Packaging Technology
Broadley-James
Cambridge Scientific Products
Organisations Mentioned in This Report
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Contents
Camile Products
Carolina Biological Supply
CEA Instruments
Cellexus
CELLution Biotech
Chemap
Colder Products Company
Columbus Instruments International
CPG
CRC Press
Curtin Matheson Scientific
Dan Kar Corporation
Dynalon Products
Eagle Manufacturing Company
EMA (EU)
Eppendorf
ExcellGene
FDA (US)
Finesse
G&G Technologies
G-Con
GE Healthcare
Gerresheimer
Glastron /Tech Glass
GoIndustry DoveBid
Guthrie Medicare Products
HEMCO Corporation
Hydrite Chemical Co.
Immunetics
Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria
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Contents
INTEGRA Biosciences - Viaflo Corporation
InVitro International
Jencons Scientific
Kimble/Kontes (A company of The Gerresheimer Group)
Kleiner Perkins Caufield & Byers
Kuhner
Lab-Line Instruments
Laboratory Disposable Products
Labsystems
Lonza
Markson LabSales
Materia Medica
Matrix Technologies Corporation
Meissner Filtration Products
Membrana
Merck & Co.
MHLW (Japan)
MIDSCI
Millipore
mp2-labs
Nestlé
New Brunswick Scientific
New England Glove Company
Nilfisk Industrial Vacuums
Nova Biomedical
Omni International
Pall Life Sciences - BioPharmaceuticals
PBS Biotech
Pegasus Scientific
Pierre Guerin
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Contents
Poly-Pipets
Pope Scientific
Precision Weighing Balances
Presens
Qosina Corporation
QPS Medical Disposable Products
Recycle & Reuse Industries
Sartorius Stedim Biotech
SCG Capital
Schleicher & Schuell
Scientific Adsorbents
SciLog
Siemens Industry- Water Technologies
Sigma Chemical Company
SmartFlow Technologies
Spectrum Chemicals & Laboratory Products
Spectrum Laboratories
Synthecon Incorporated
Texas A&M University
The Chemical Company
The Lee Company
Thermo Fisher Scientific
Thermo Scientific Nalgene and Nunc
Thomas Scientific
Unisyn Medical Technologies
United Laboratory Plastics
USA Scientific
VantagePoint Venture Partners
Veolia Water Solutions & Technologies
VirTis (an SP Industries Brand)
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Contents
VWR International
WAVE Biotech
Westfalia Separator
Wheaton Science Products
Worcester Polytechnic Institute, Worcester, MA, USA
Xcellerex
Page 47www.visiongain.com
Single-Use Bioreactors for Pharma:
World Market 2013-2023
Growth in those markets will be driven by increasing uptake of biotherapeutic agents using single-
use bioreactor technologies. By 2023, the combined revenues of the German, UK, French, Italian
and Spanish markets will be $26.8m, achieving a CAGR of 5.8% for the period 2012 to 2023.
Higher growth rates still are expected in eastern European markets, owing to rapid economic
growth in these countries, with rising demand for vaccines and other biologic agents.
3.4.4 Emerging National Markets for Single-Use Bioreactor Technology
The market for single-use bioreactors technology systems is growing rapidly in developing
countries, where rising standards of living and rapid growth in numbers of elderly people are
increasing the demand for biologic pharmaceuticals, with cancer being an important treatment
area. In 2012, the leading emerging-economy markets for single-use bioreactors were those of
China ($2.9m) and India ($0.6m), with combined other markets group generating revenues of
$1.6m (Table 3.19). During the forecast period, 2012 to 2023, the Chinese and Indian pharma
industries will be among the most rapidly growing in the world. This growth will benefit the single-
use bioreactors industry and market.
3.4.5 The Chinese Single-Use Bioreactors Technology Market, 2013-
2023
The Chinese single-use bioreactors technology market was worth an estimated $2.9m in 2012, a
5.5% share of the world market. The Chinese pharmaceutical market is expanding rapidly, driven
by that country's rapid economic development, the rise of personal incomes and improvements in
the country's medical system, especially wider healthcare coverage. Western medicines are
becoming widely accepted in China, and there is also a shift to western-style diets and lifestyles,
which is likely to be responsible for an increasing demand for pharmaceutical products (including
biologic drugs and vaccines).
As a result, the total Chinese market for single-use bioreactor technologies will grow rapidly from
2012 to 2023. Growth will be highest from 2012 to 2017. By 2017, the market will be worth $5.6m,
with a CAGR of 14.1% from 2012 to 2017 (Tables 3.15-3.16 and Figures 3.11 and 3.15-3.18). After
2017, growth will slow, as the Chinese economy stabilises after a period of rapid growth. By 2023,
its single-use bioreactors market will have reached $8.0m, representing a CAGR of 9.8% from
2012 to 2023.
Page 48www.visiongain.com
Single-Use Bioreactors for Pharma:
World Market 2013-2023
Table 3.16 The Chinese Single-Use Bioreactors National Market
Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023
Table 3.15 The Chinese Single-Use Bioreactors National Market
Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017
Source: visiongain 2013; CAGR values are for 2012-2017
Source: visiongain 2013; CAGR values are for 2018-2023
Year 2012 2013 2014 2015 2016 2017
China ($m) 2.9 3.5 4.0 4.5 5.0 5.6
Annual Growth (%) 22.3 14.5 12.7 10.3 11.1
CAGR (%) 14.1
Year 2018 2019 2020 2021 2022 2023
China ($m) 6.0 6.5 6.9 7.3 7.6 8.0
Annual Growth (%) 8.8 7.4 6.4 5.2 5.1 5.0
CAGR (%) 5.8
Figure 3.11 China: Single-Use Bioreactors National Market Revenue ($m)
Forecast, 2012-2023
Source: visiongain 2013
2.9
3.5
4.0
4.5
5.0
5.6
6.0
6.5
6.9
7.3
7.6
8.0
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
9.0
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023
Sales($m)
Year
China

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Single-Use Bioreactors for Pharma: World Market 2013-2023

  • 1. ©notice This material is copyright 2010 by visiongain. It is against the law to reproduce any of this material without the prior written agreement of visiongain. You cannot photocopy, fax, download to database or duplicate in any other way any of the material contained in this report. Each purchase and single copy is for personal use only. Single-Use Bioreactors for Pharma: World Market 2013-2023
  • 2. www.visiongain.com Contents 1.1 Single-Use Bioreactors: Market Review 1.2 Aims, Scope and Format of the Report 1.3 Research and Analysis Methods 2.1 Introduction 2.1.1 Historical Perspective: A Brief Overview 2.2 The Wave Bioreactor 2.3 Current Single-Use Systems on the Market 2.3.1 Stirred Flexible Disposable Bioreactors 2.3.2 Non-Stirred Flexible Disposable Bioreactors 2.3.3 Stirred Rigid Disposable Bioreactors 2.3.4 Non-Stirred Rigid Disposable Bioreactors 2.3.5 Fixed-Bed Bioreactors 2.4 Construction Material for Single-Use Bioreactors 2.5 Measurement and Control for Single-Use Bioreactors 2.6 Main Applications of Disposable Bioreactors 3.1 The World Single-Use Bioreactors Market in 2012 3.2 Growing Market for Single-Use Bioreactor Systems 3.2.1 Sales Forecast for Overall Single-Use Bioreactors Market, 2012-2017 3.2.2 Sales Forecast for Overall Single-Use Bioreactors Market, 2018-2023 3.3 Breakdown of the Global Single-Use Bioreactors Market 3. The World Market for Single-Use Bioreactors, 2013-2023 2. Single-Use Bioreactor Technologies: an Introduction 1. Executive Summary
  • 3. www.visiongain.com Contents 3.3.1 Sales Forecast for Single-Use Bioreactors: Hardware Modules/Systems, 2012-2017 3.3.2 Sales Forecast for Single-Use Bioreactors: Hardware Modules/Systems, 2018-2023 3.3.3 Sales Forecast for Single-Use Bioreactors: Disposables and Accessories, 2012-2017 3.3.4 Sales Forecast for Single-Use Bioreactors: Disposables and Accessories, 2018-2023 3.4 Leading National Markets for Single-Use Bioreactors Technology, 2013-2023 3.4.1 The US Market for Single-Use Bioreactors Technology, 2013-2023 3.4.2 The Japanese Single-Use Bioreactors Technology Market, 2013-2023 3.4.3 The Leading European Single-Use Bioreactors Technology Markets, 2013-2023 3.4.4 Emerging National Markets for Single-Use Bioreactor Technology 3.4.5 The Chinese Single-Use Bioreactors Technology Market, 2013-2023 3.4.6 The Indian Single-Use Bioreactors Technology Market, 2013-2023 4.1 Introduction 4.2 Xcellerex 4.2.1 Overview 4.2.2 Products, Platforms & Technology 4.2.2.1 FlexFactory Biomanufacturing Platform 4.2.2.2 XDR Single-Use Bioreactors 4.2.2.3 XDM QUAD Single-Use Mixing Systems 4.2.2.4 XDA Disposable Assembly 4.2.2.5 Process Development Services 4.2.2.6 FlexFactory Services 4.2.3 Finances 4.2.4 Xcellerex Milestones & Recent Developments 4.2.5 GreenVax Selects Xcellerex XDR Single-Use Bioreactors for New Vaccine and Biotherapeutics Programme 4.2.6 Future Outlook and Commercial Strategy 4. Leading Companies in the Market
  • 4. www.visiongain.com Contents 4.2.7 GE Healthcare Completes Acquisition of Xcellerex 4.3 Cellexus Limited 4.3.1 Overview 4.3.2 Global Presence 4.3.3 Products 4.3.4 CellexusBag 4.3.5 CellMaker PLUS 4.3.5.1 CellMaker PLUS Components 4.3.5.2 CellMaker PLUS Dimensions and Specifications 4.3.6 The Cellexus Oxygenator 4.3.6.1 Cellexus Oxygenator: Main Features and Benefits 4.3.6.2 Cellexus Oxygenator Dimensions and Specifications 4.3.7 Single-Use Bioreactor Cell Culture Control Instrumentation 4.3.8 Cellexus Airlift Proprietary Technologies 4.3.9 Single-Use, Non-Penetrative Sensor Technology 4.3.10 Future Outlook 4.4 Sartorius Stedim Biotech 4.4.1 Overview 4.4.2 International Presence 4.4.3 Services and Products 4.4.4 Revenues 4.4.5 Future Outlook 4.5 Thermo Scientific Hyclone 4.5.1 Overview 4.5.2 Global Presence 4.5.3 Thermo Scientific HyClone Products 4.5.4 Thermo Scientific HyClone (SUB): A Disposable Alternative to Conventional Stirred Tank Bioreactors 4.5.5 Hyclone SUB Components 4.5.6 Future Outlook
  • 5. www.visiongain.com Contents 4.6 GE Healthcare 4.6.1 Overview 4.6.2 Global Presence 4.6.3 Bioreactor Products 4.6.4 WAVE Bioreactor Systems 4.6.5 Cell Culture Products 4.6.6 Mixing Products 4.6.7 Fluid Transfer Products 4.6.8 M&A Activity 4.6.9 Future Outlook 4.7 PBS Biotech 4.7.1 Overview 4.7.2 Global Footprint 4.7.3 PBS Design and Air Wheel Mixing System 4.7.4 Applications & Processes 4.7.5 PBS Specialties 4.7.6 Main Products 4.7.7 Company Highlights 4.7.8 Future Outlook 4.8 ATMI LifeSciences 4.8.1 Overview 4.8.2 Global Footprint 4.8.3 ATMI Specialties 4.8.4 Main Bioreactor Products 4.8.4.1 iCELLis 4.8.4.2 Nucleo Single-Use Bioreactor 4.8.4.3 PadReactor Single-Use Bioreactor 4.8.4.4 Xpansion Bioreactor 4.8.4.5 Bag Conversion 4.8.5 Other Disposable Products
  • 6. www.visiongain.com Contents 4.8.6 Financial Performance 4.8.7 Future Outlook 5.1 Introduction 5.2 Commercial Drivers of the Single-Use Bioreactors Market 5.2.1 Cost Reduction: A Major Driver in Disposable Bioreactors Market 5.2.2 Comparison of Single-Use and Traditional Manufacturing Systems 5.3 Commercial Restraints for the Single-Use Bioreactors Market 5.3.1 Disposable Bioreactors and their Impact on the Environment 5.3.2 Options for Waste Disposal for Bioreactors 5.3.3 Lack of Defined ‘Leachable and Extractable’ Standards Causing Concern 5.3.4 Disposable Bioreactors Unlikely to Replace Traditional Manufacturing Systems Entirely 5.3.5 Scalability and Size Limitations Still Concern Biomanufacturers 5.4 Challenges Facing the Single-Use Bioreactor Technology Industry and Market 5.4.1 Bottlenecks in Downstream Processing 5.5 Summary 6.1 Interview with Mr Christian Julien, Business Development Manager, Meissner Filtration Products, Inc. Camarillo, California, USA 6.1.1 On Current Market for Single-Use Bioreactors 6.1.2 On Key Unmet Needs in the Market for Single-Use Bioreactors 6.1.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology 6.1.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.1.5 On Advantages of Disposable Technology 6.1.6 On Major Drawbacks of Single-Use Bioreactor Technology 6. Research Interviews from Our Survey 5. Qualitative Analysis of the Single-Use Bioreactor Technology Market
  • 7. www.visiongain.com Contents 6.1.7 On New Developments in the Single-Use Bioreactors Sector 6.1.8 On Pipeline Technology in the Single-Use Bioreactors Market 6.2 Interview with Dr Karl G. Schick, PhD, Vice President of Research & Development, SciLog Inc., Madison, Wisconsin, USA 6.2.1 On Current Market for Single-Use Bioreactors 6.2.2 On Key Unmet Needs in the Market for Single-Use Bioreactors 6.2.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology 6.2.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.2.5 On Advantages of Disposable Technology 6.2.6 On Major Drawbacks of Single-Use Bioreactor Technology 6.2.7 On New Developments in the Single-Use Bioreactors Sector 6.2.8 On Pipeline Technology in the Single-Use Bioreactors Market 6.3 Interview with Professor Pamela J. Weathers, PhD, Biology & Biotechnology Dept., Worcester Polytechnic Institute, Worcester, MA, USA 6.3.1 On Current Market for Single-Use Bioreactors 6.3.2 On Key Unmet Needs in the Market for Single-Use Bioreactors 6.3.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology 6.3.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.3.5 On Advantages of Disposable Technology 6.3.6 On Major Drawbacks of Single-Use Bioreactor Technology 6.3.7 On New Developments in the Single-Use Bioreactors Sector 6.3.8 On Pipeline Technology in the Single-Use Bioreactors Market 6.4 Interview with Professor Milen Georgiev, PhD, Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria 6.4.1 On Current Market for Single-Use Bioreactors 6.4.2 On Key Unmet Needs in the Market for Single-Use Bioreactors 6.4.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology 6.4.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.4.5 On Advantages of Disposable Technology 6.4.6 On Major Drawbacks of Single-Use Bioreactor Technology
  • 8. www.visiongain.com Contents 6.4.7 On New Developments in the Single-Use Bioreactors Sector 6.5 Interview with James B. Schultz, Vice President, Sales & Marketing, PBS Biotech, Camino Ranchero, Camarillo, CA, USA 6.5.1 On Current Market for Single-Use Bioreactors 6.5.2 On Key Unmet Needs in the Market for Single-Use Bioreactors 6.5.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology 6.5.4 On Advantages of Disposable Technology 6.5.5 On Major Drawbacks of Single-Use Bioreactor Technology 6.5.6 On New Developments in the Single-Use Bioreactors Sector 6.5.7 On Technologies in Pipeline for the Single-Use Bioreactors Sector 6.6 Interview with Dr Tibor Anderlei, Head of Science and Business Development, Adolf Kühner, Dinkelbergstr, Birsfelden, Basel, Switzerland 6.6.1 On Current Market for Single-Use Bioreactors 6.6.2 On Key Unmet Needs in the Market for Single-Use Bioreactors 6.6.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology 6.6.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.6.5 On Advantages of Disposable Technology 6.6.6 On Major Drawbacks of Single-Use Bioreactor Technology 6.6.7 On Technologies in the Pipeline for the Single-Use Bioreactors Sector 6.7 Interview with Dr Jean Paul Ducos, Nestlé R&D Centre Tours, France 6.7.1 On Plant Propagation R&D and Areas of Focus in Single-Use Bioreactor Technology 6.7.2 On Main Challenges in Plant Propagation Research and Single-Use Bioreactor Technology 6.7.3 On Advantages of Single-Use Bioreactor Technology for Plant Propagation 6.7.4 On Drawbacks of Single-Use Bioreactor Technology in Plant Propagation 6.7.5 On New Developments in Single-Use Bioreactors Sector 6.7.6 On Pipeline Technology in Single-Use Bioreactors Market 6.8 Interview with William Whitford, Sr. Technical Market Manager, Thermo Scientific Cell Culture & BioProcessing, Thermo Fisher Scientific, Utah, USA 6.8.1 On Current SUB Market
  • 9. www.visiongain.com Contents 6.8.2 On Key Unmet Needs in the Single-Use Bioreactors Market 6.8.3 On Key Areas of Focus in Single-Use Bioreactor Technology 6.8.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.8.5 On Advantages of Disposable Technology 6.8.6 On Major Drawbacks of Single-Use Bioreactor Technology 6.8.7 On R&D and SUB Sector 6.8.8 On Pipeline Products and Technologies in the Single-Use Bioreactors Sector 6.9 Dr. Gerhard Greller, R&D Director Upstream Technology, Sartorius Stedim Biotech, Goettingen, Germany 6.9.1 On Current SUB Market 6.9.2 On Key Unmet Needs in the Single-Use Bioreactors Market 6.9.3 On Key Areas of Focus in Single-Use Bioreactor Technology 6.9.4 On Main Challenges Facing the Single-Use Bioreactors Market 6.9.5 On Advantages of Disposable Technology 6.9.6 On Major Drawbacks of Single-Use Bioreactor Technology 6.9.7 On R&D and SUB Sector 6.9.8 On Pipeline Products and Technologies in the Single-Use Bioreactors Sector 6.10 Overview of the Biotech Industry in 2013: Interview with Ronald A. Rader, President of Biotechnology Information Institute (BII) 6.10.1 Steady Growth, but a Dearth of New Blockbusters 6.10.2 The Price of Biological Drugs 6.10.3 Biosimilars to Outnumber Innovator Products 6.10.4 ‘Differentiated Biologics’: Biosimilars Vs Bio-Betters 6.10.5 Changing of the Guard: Can New Classes of Biopharmaceuticals Transform the Market? 6.10.6 Big Pharma and the Biotechs 6.10.7 Bundled Payments and Bulked-up Portfolios, and Other Reasons Why Every Major Player Will Get Involved in Biosimilars 6.10.8 Modular Bioprocessing: The Next Revolution?
  • 10. www.visiongain.com Contents 7.1 Overview 7.2 Prominent Companies in the Market 7.3 Commercial Drivers of the Single-Use Bioreactors Market 7.4 Future Outlook and Concluding Remarks 7. Conclusions: Single-Use Bioreactor Systems – a Growth Market
  • 11. www.visiongain.com Contents Table 2.1 A Selection of Single-Use Bioreactor Systems on the Market, 2013 Table 3.1 World Single-Use Bioreactors Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 Table 3.2 World Single-Use Bioreactors Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.3 World Single-Use Bioreactors: Market Hardware Modules/Systems Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017 Table 3.4 World Single-Use Bioreactors Market: Hardware Modules/Systems Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023 Table 3.5 World Single-Use Bioreactors Market: Disposables and Accessories Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017 Table 3.6 World Single-Use Bioreactors Market: Disposables and Accessories Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023 Table 3.7 Single-Use Bioreactors Submarket Revenue Forecast ($m), AGR (%), CAGR (%), 2012- 2017 Table 3.8 Single-Use Bioreactors Submarket Revenue Forecast ($m), AGR (%), CAGR (%), 2018- 2023 Table 3.9 The US Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 Table 3.10 The US Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.11 The Japanese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 Table 3.12 The Japanese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.13 The EU 5 Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 List of Tables
  • 12. www.visiongain.com Contents Table 3.14 The EU 5 Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.15 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 Table 3.16 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.17 The Indian Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 Table 3.18 The Indian Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.19 Single-Use Bioreactors: Leading National Markets Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017 Table 3.20 Single-Use Bioreactors: Leading National Market Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023 Table 4.1 Single-Use Bioreactors: Manufacturers and Suppliers, 2013 Table 4.2 CellMaker PLUS Component Dimensions and Specifications, 2013 Table 4.3 Cellexus Oxygenator Dimensions and Specifications, 2013 Table 5.1 SWOT Analysis: Strengths and Weaknesses of the World Single-Use Bioreactors Market, 2013-2023 Table 5.2 SWOT Analysis: Opportunities and Threats in the World Single-Use Bioreactors Market, 2013-2023 Table 5.3 Comparison of Disposal Options for Single-Use Bioreactor System, 2013 Table 7.1 Single-Use Bioreactors Market: World Revenue Forecast ($m), AGR (%), CAGR (%) by Sector in 2012, 2014, 2017, 2020 and 2023
  • 13. www.visiongain.com Contents Figure 2.1 Main Applications and Classes of Disposable Bioreactors, 2013 Figure 3.1 World Single-Use Bioreactors Market Revenue Forecast ($m), 2012-2017 Figure 3.2 World Single-Use Bioreactors Market Revenue Forecast ($m), 2018-2023 Figure 3.3 World Single-Use Bioreactors Market: Hardware Modules/ Systems Revenue ($m) Forecast, 2012-2017 Figure 3.4 World Single-Use Bioreactors Market: Hardware Modules/Systems Revenue ($m) Forecast, 2018-2023 Figure 3.5 World Single-Use Bioreactors Market: Disposables and Accessories Revenue ($m) Forecast, 2012-2017 Figure 3.6 World Single-Use Bioreactors Market: Disposables & Accessories Revenue ($m) Forecast, 2018-2023 Figure 3.7 Single-Use Bioreactors: Submarket Revenue ($m) Forecasts, 2012-2023 Figure 3.8 The US Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023 Figure 3.9 Japan: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023 Figure 3.10 EU 5 Countries: Single-Use Bioreactors National Market Revenue ($m) Forecasts, 2012-2023 Figure 3.11 China: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023 Figure 3.12 India: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023 Figure 3.13 US, Japan and Total Worldwide Single-Use Bioreactors Markets: Revenue ($m) Forecasts, 2012-2023 Figure 3.14 EU 5 and Other Leading Single-Use Bioreactors National Markets: Revenue ($m) Forecasts, 2012-2023 Figure 3.15 Single-Use Bioreactors: National Market Revenue Shares (%), 2012 Figure 3.16 Single-Use Bioreactors: National Market Revenue Shares (%), 2017 Figure 3.17 Single-Use Bioreactors: National Market Revenue Shares (%), 2020 Figure 3.18 Single-Use Bioreactors: National Market Revenue Shares (%), 2023 Figure 4.1 Xcellerex: Opportunities and Threats, 2013-2023 Figure 4.2 Cellexus: Opportunities and Threats, 2013-2023 List of Figures
  • 14. www.visiongain.com Contents Figure 4.3 Sartorius Stedim Biotech: Opportunities and Threats, 2013-2023 Figure 4.4 Thermo Scientific Hyclone: Opportunities and Threats, 2013-2023 Figure 4.5 GE Healthcare: Opportunities and Threats, 2013-2023 Figure 4.6 PBS Biotech: Opportunities and Threats, 2013-2023 Figure 4.7 ATMI: Opportunities and Threats, 2013-2023 Figure 5.1 Estimated Cost Savings of Single-Use Bioreactors in Comparison with Stainless Steel Systems, 2013 Figure 5.2 Disposal Route Taken by Companies for Single-Use Plastic Materials, 2009 Figure 7.1 The Single-Use Bioreactors Market: Market Shares (%) in The Worldwide Single-Use Systems Market, 2012 Figure 7.2 Single-Use Bioreactors Market: World Revenue Forecast ($m) by Segment in 2012, 2014, 2017, 2020 and 2023
  • 15. www.visiongain.com Contents 3M Occupational Health & Environmental Safety A Daigger & Company ABEC Adolf Kühner Aeronex Air Products and Chemicals Alconox American Health & Safety American Instrument Exchange Amgen AmProtein Anachemia Science Applikon Biotechnology Artelis Artisan Industries Inc. Ashland Chemical Co. ATL (Ad Tape & Label) ATMI Bayer Technology Bel-Art Products Bellco Glass Bioengineering AG BioProcess Systems Alliance (BPSA) Bio-Recovery Biotechnology Information Institute (BII) Bosch Packaging Technology Broadley-James Cambridge Scientific Products Organisations Mentioned in This Report
  • 16. www.visiongain.com Contents Camile Products Carolina Biological Supply CEA Instruments Cellexus CELLution Biotech Chemap Colder Products Company Columbus Instruments International CPG CRC Press Curtin Matheson Scientific Dan Kar Corporation Dynalon Products Eagle Manufacturing Company EMA (EU) Eppendorf ExcellGene FDA (US) Finesse G&G Technologies G-Con GE Healthcare Gerresheimer Glastron /Tech Glass GoIndustry DoveBid Guthrie Medicare Products HEMCO Corporation Hydrite Chemical Co. Immunetics Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria
  • 17. www.visiongain.com Contents INTEGRA Biosciences - Viaflo Corporation InVitro International Jencons Scientific Kimble/Kontes (A company of The Gerresheimer Group) Kleiner Perkins Caufield & Byers Kuhner Lab-Line Instruments Laboratory Disposable Products Labsystems Lonza Markson LabSales Materia Medica Matrix Technologies Corporation Meissner Filtration Products Membrana Merck & Co. MHLW (Japan) MIDSCI Millipore mp2-labs Nestlé New Brunswick Scientific New England Glove Company Nilfisk Industrial Vacuums Nova Biomedical Omni International Pall Life Sciences - BioPharmaceuticals PBS Biotech Pegasus Scientific Pierre Guerin
  • 18. www.visiongain.com Contents Poly-Pipets Pope Scientific Precision Weighing Balances Presens Qosina Corporation QPS Medical Disposable Products Recycle & Reuse Industries Sartorius Stedim Biotech SCG Capital Schleicher & Schuell Scientific Adsorbents SciLog Siemens Industry- Water Technologies Sigma Chemical Company SmartFlow Technologies Spectrum Chemicals & Laboratory Products Spectrum Laboratories Synthecon Incorporated Texas A&M University The Chemical Company The Lee Company Thermo Fisher Scientific Thermo Scientific Nalgene and Nunc Thomas Scientific Unisyn Medical Technologies United Laboratory Plastics USA Scientific VantagePoint Venture Partners Veolia Water Solutions & Technologies VirTis (an SP Industries Brand)
  • 19. www.visiongain.com Contents VWR International WAVE Biotech Westfalia Separator Wheaton Science Products Worcester Polytechnic Institute, Worcester, MA, USA Xcellerex
  • 20. Page 47www.visiongain.com Single-Use Bioreactors for Pharma: World Market 2013-2023 Growth in those markets will be driven by increasing uptake of biotherapeutic agents using single- use bioreactor technologies. By 2023, the combined revenues of the German, UK, French, Italian and Spanish markets will be $26.8m, achieving a CAGR of 5.8% for the period 2012 to 2023. Higher growth rates still are expected in eastern European markets, owing to rapid economic growth in these countries, with rising demand for vaccines and other biologic agents. 3.4.4 Emerging National Markets for Single-Use Bioreactor Technology The market for single-use bioreactors technology systems is growing rapidly in developing countries, where rising standards of living and rapid growth in numbers of elderly people are increasing the demand for biologic pharmaceuticals, with cancer being an important treatment area. In 2012, the leading emerging-economy markets for single-use bioreactors were those of China ($2.9m) and India ($0.6m), with combined other markets group generating revenues of $1.6m (Table 3.19). During the forecast period, 2012 to 2023, the Chinese and Indian pharma industries will be among the most rapidly growing in the world. This growth will benefit the single- use bioreactors industry and market. 3.4.5 The Chinese Single-Use Bioreactors Technology Market, 2013- 2023 The Chinese single-use bioreactors technology market was worth an estimated $2.9m in 2012, a 5.5% share of the world market. The Chinese pharmaceutical market is expanding rapidly, driven by that country's rapid economic development, the rise of personal incomes and improvements in the country's medical system, especially wider healthcare coverage. Western medicines are becoming widely accepted in China, and there is also a shift to western-style diets and lifestyles, which is likely to be responsible for an increasing demand for pharmaceutical products (including biologic drugs and vaccines). As a result, the total Chinese market for single-use bioreactor technologies will grow rapidly from 2012 to 2023. Growth will be highest from 2012 to 2017. By 2017, the market will be worth $5.6m, with a CAGR of 14.1% from 2012 to 2017 (Tables 3.15-3.16 and Figures 3.11 and 3.15-3.18). After 2017, growth will slow, as the Chinese economy stabilises after a period of rapid growth. By 2023, its single-use bioreactors market will have reached $8.0m, representing a CAGR of 9.8% from 2012 to 2023.
  • 21. Page 48www.visiongain.com Single-Use Bioreactors for Pharma: World Market 2013-2023 Table 3.16 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023 Table 3.15 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017 Source: visiongain 2013; CAGR values are for 2012-2017 Source: visiongain 2013; CAGR values are for 2018-2023 Year 2012 2013 2014 2015 2016 2017 China ($m) 2.9 3.5 4.0 4.5 5.0 5.6 Annual Growth (%) 22.3 14.5 12.7 10.3 11.1 CAGR (%) 14.1 Year 2018 2019 2020 2021 2022 2023 China ($m) 6.0 6.5 6.9 7.3 7.6 8.0 Annual Growth (%) 8.8 7.4 6.4 5.2 5.1 5.0 CAGR (%) 5.8 Figure 3.11 China: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023 Source: visiongain 2013 2.9 3.5 4.0 4.5 5.0 5.6 6.0 6.5 6.9 7.3 7.6 8.0 0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 Sales($m) Year China