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Cancer drugs side effects

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cancer drug side effects is a very important topic for pg entrance....so all important points and mcqs with images have been given here....do make use of it

cancer drug side effects is a very important topic for pg entrance....so all important points and mcqs with images have been given here....do make use of it

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Cancer drugs side effects

  1. 1. DRUG IMPORTANT SIDE EFFECTS ALKYLATING AGENTS Secondary Leukemias Busulfan Lung fibrosis Bleomycin Lung fibrosis Cyclophosphomide Hemorrhagic Cystitis Nitrosureas (Carmustine) Persistent Neutropenia Cisplatin Most emitogenic Nephrotoxic, Ototoxic Carboplatin Maximum Bone marrow suppression Methotrexate Megaloblastic Anemia/Hepatotoxic 6-Mercaptopurine / 6- Thioguanine Hepatotoxic 5-FU Hand and foot disease
  2. 2. Capecitabine Hand and foot disease Cytarabine (Arabinofuranisyl Cytidine) Cerebellar Ataxia Vincristine SIADH, Peripheral Neuropathy Vinblastine Bone marrow suppression Paclitaxel Allergy, Peripheral Neuropathy Etoposide Secondary Leukemias Anthracyclines (Doxorubocin, Daunorubocin) Cardiotoxic L-Asparaginase Allergy Pancreatitis Hypercoagulable Sx Imatinib Rash
  3. 3. Tacrolimus Nephrotoxic, Neurotoxic, Alopecia, Precipitates DM But not Ototoxic Cyclosporine Nephrotoxic, Increase Infection Risk, Hepatotoxic Thalidomide S –Sedation Po- Phocomelia, Peripheral neuropathy R – Rash T – Thrombosis Channel – Constipation Mycophenolate and Azathioprine Bone marrow suppression Leflunomide Liver and lung injury

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