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Composition and significance
of nucleic acids

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Composition of nucleic acids
• Nucleic acids are linear polymers(chains) of
nucleotides.
• Each nucleotide consists of thr...

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Composition of nucleic acids
• A substructure of nucleotides formed of a nucleobase plus sugar is
termed as nucleoside.
• ...

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Nucliec acids

  1. 1. Composition and significance of nucleic acids
  2. 2. Composition of nucleic acids • Nucleic acids are linear polymers(chains) of nucleotides. • Each nucleotide consists of three components: a) A purine or pyrimidine nucleobase(sometimes termed nitrogenous base or simply base) b) A pentose sugar c) And A phosphate group
  3. 3. Composition of nucleic acids • A substructure of nucleotides formed of a nucleobase plus sugar is termed as nucleoside. • In their nucleotides DNA contains 2’-deeoxyrribose while RNA contains ribose. • Here only the difference is of the presence off a hydroxyl group. • The nucleobases found in two nucleic acid types are different : adenine, cytosine, and guanine are found in both DNA and RNA. • Thymine occurs in DNA and uracil occurs in RNA. • Phosphoric acid when attaches to a nucleoside forms nucleotide.
  4. 4. •Nucleoside •Nucleotides
  5. 5. a) Pentose sugar b) Nitrogenous base 1. Purines 2. Pyrimidines
  6. 6. c) Phosphate group d) Sugar phosphate backbone
  7. 7. • Extra stability of nitrogenous bases due to tautomerism • Examples of tautomeric forms
  8. 8. Nucleotide structure PHOSPHATE SUGAR Ribose or Deoxyribose NUCLEOTIDE BASE PURINES PYRIMIDINES Adenine (A) Guanine(G) Cytocine (C) Thymine (T) Uracil (U) © 2016 Paul Billiet ODWS
  9. 9. Significance of nucleic acids • The storage and transmission of genetic information • Source of information for synthesis of all proteins • In cell division DNA serves as a source of information inherited by progeny cells.
  10. 10. Nucleotides can also function as a carrier of chemical energy for example :
  11. 11. Any Question ?

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