SlideShare a Scribd company logo

Lecture 1

•Download as PPT, PDF•
•
A
ammar905
1 of 47
International University of Africa Faculty of Pharmacy Medicinal Chemistry MCHM 311 Siddieg Omer Elsiddieg, M. Sc, B. Sc (Honors)
Class Policies and Rules ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What Is Medicinal Chemistry?
[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Drugs of Antiquity ,[object Object],[object Object],[object Object]
The Middle Ages ,[object Object]
The Nineteenth Century ,[object Object],[object Object],[object Object],[object Object]
The twentieth Century ,[object Object],[object Object],[object Object]
 
[object Object]
[object Object]
[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
[object Object]
[object Object],[object Object]
Drug Discovery and Design ,[object Object],[object Object],[object Object]
 
Lead Compounds ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sources of Drugs and Lead Compounds ,[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
 
Yew Tree
Drug Synthesis ,[object Object],[object Object],[object Object],[object Object]
 
Me-Too Drugs ,[object Object],[object Object]
Classification of Drugs ,[object Object],[object Object],[object Object]
[object Object]
 
Routes of Administration
Pharmacokinetics Phase ,[object Object]
Absorption ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Distribution ,[object Object],[object Object]
Metabolism ,[object Object],[object Object],[object Object]
 
Elimination ,[object Object],[object Object],[object Object]
Bioavailability of Drugs ,[object Object],[object Object]
Pharmacodynamic Phase ,[object Object],[object Object]
[object Object]

Recommended

Medicinal chemistry
Medicinal chemistryMedicinal chemistry
Medicinal chemistry
akkimi padama
 
Bioisosterism - Introduction
Bioisosterism - IntroductionBioisosterism - Introduction
Bioisosterism - Introduction
Anbarasan Rajagopal
 
Introduction of Medicinal chemistry
Introduction of Medicinal chemistryIntroduction of Medicinal chemistry
Introduction of Medicinal chemistry
vishvajitsinh Bhati
 
Introduction To Medicinal Chemistry
Introduction To Medicinal ChemistryIntroduction To Medicinal Chemistry
Introduction To Medicinal Chemistry
Pradnya Gondane
 
Heterocyclic Organic Reaction - By Vishal Dakhale
Heterocyclic Organic Reaction - By Vishal DakhaleHeterocyclic Organic Reaction - By Vishal Dakhale
Heterocyclic Organic Reaction - By Vishal Dakhale
VishalDakhale
 
PRODRUG DESIGN [M.PHARM]
PRODRUG DESIGN [M.PHARM]PRODRUG DESIGN [M.PHARM]
PRODRUG DESIGN [M.PHARM]
Shikha Popali
 
Combinatorial chemistry
Combinatorial chemistryCombinatorial chemistry
Combinatorial chemistry
Bhaskar_Borkar
 
1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY
1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY 1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY
1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY
SONALI PAWAR
 

Recommended

Medicinal chemistry
Medicinal chemistryMedicinal chemistry
Medicinal chemistry
akkimi padama
 
Bioisosterism - Introduction
Bioisosterism - IntroductionBioisosterism - Introduction
Bioisosterism - Introduction
Anbarasan Rajagopal
 
Introduction of Medicinal chemistry
Introduction of Medicinal chemistryIntroduction of Medicinal chemistry
Introduction of Medicinal chemistry
vishvajitsinh Bhati
 
Introduction To Medicinal Chemistry
Introduction To Medicinal ChemistryIntroduction To Medicinal Chemistry
Introduction To Medicinal Chemistry
Pradnya Gondane
 
Heterocyclic Organic Reaction - By Vishal Dakhale
Heterocyclic Organic Reaction - By Vishal DakhaleHeterocyclic Organic Reaction - By Vishal Dakhale
Heterocyclic Organic Reaction - By Vishal Dakhale
VishalDakhale
 
PRODRUG DESIGN [M.PHARM]
PRODRUG DESIGN [M.PHARM]PRODRUG DESIGN [M.PHARM]
PRODRUG DESIGN [M.PHARM]
Shikha Popali
 
Combinatorial chemistry
Combinatorial chemistryCombinatorial chemistry
Combinatorial chemistry
Bhaskar_Borkar
 
1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY
1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY 1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY
1 UNIT I: INTRODUCTION TO MEDICINAL CHEMISTRY
SONALI PAWAR
 
BIOISOSTERSM
BIOISOSTERSMBIOISOSTERSM
BIOISOSTERSM
Tuba Khan
 
Medicinal chemistry i
Medicinal chemistry iMedicinal chemistry i
Medicinal chemistry i
priya yadav
 
Analog design medicinal chemistry
Analog design medicinal chemistryAnalog design medicinal chemistry
Analog design medicinal chemistry
Mohit umare
 
Drug design
Drug designDrug design
Drug design
Shikha Popali
 
History of Medicinal Chemistry
History of Medicinal ChemistryHistory of Medicinal Chemistry
History of Medicinal Chemistry
Lalita Dahiwade
 
Medicinal chemistry
Medicinal chemistry Medicinal chemistry
Medicinal chemistry
Aryavarta Giri
 
Rationale of prodrug design and practical considertions of prodrug design
Rationale of prodrug design and practical considertions of prodrug designRationale of prodrug design and practical considertions of prodrug design
Rationale of prodrug design and practical considertions of prodrug design
Keshari Sriwastawa
 
Physicochemical Properties of Drug
Physicochemical Properties of DrugPhysicochemical Properties of Drug
Physicochemical Properties of Drug
Priyanka Mittal
 
Medicinal chemistry Basics
Medicinal chemistry BasicsMedicinal chemistry Basics
Medicinal chemistry Basics
Rahul Patil PhD
 
Combinatorial chemistry
Combinatorial chemistryCombinatorial chemistry
Combinatorial chemistry
Harendra Bisht
 
PRODRUGS
PRODRUGSPRODRUGS
PRODRUGS
NAGA PRASHANT KOPPURAVURI
 
Medicinal chemistry Basics
Medicinal chemistry BasicsMedicinal chemistry Basics
Medicinal chemistry Basics
Rahul Patil PhD
 
Hammett parameters
Hammett parametersHammett parameters
Hammett parameters
Daniel Morton
 
Qsar
QsarQsar
Qsar
nehla313
 
3. stereochemistry of steroids
3. stereochemistry of steroids3. stereochemistry of steroids
3. stereochemistry of steroids
DR.Gopinathan Narasimhan
 
Antibiotics - Medicinal chemistry
Antibiotics - Medicinal chemistry Antibiotics - Medicinal chemistry
Antibiotics - Medicinal chemistry
kencha swathi
 
QSAR by hansch analysis
QSAR by hansch analysisQSAR by hansch analysis
QSAR by hansch analysis
kholood adil
 
Medicinal chemistry
Medicinal chemistryMedicinal chemistry
Medicinal chemistry
Aditi Kaushik
 
Hansch and Free-Wilson QSAR Models
Hansch and Free-Wilson QSAR ModelsHansch and Free-Wilson QSAR Models
Hansch and Free-Wilson QSAR Models
Akshay Kank
 
Impurities in API , types and their sources including genotoxic impurities
Impurities in API , types and their sources including genotoxic impuritiesImpurities in API , types and their sources including genotoxic impurities
Impurities in API , types and their sources including genotoxic impurities
College of Pharmacy,Sri Ramakrishna Institute of Paramedical Sciences,Coimbatore
 
1 lab physico-chemical_properties_of_drugs[1]
1 lab physico-chemical_properties_of_drugs[1]1 lab physico-chemical_properties_of_drugs[1]
1 lab physico-chemical_properties_of_drugs[1]
Kym Anne Surmion II
 
Medicinal chemistry (drug metabolism & concept of prodrug) corrected
Medicinal chemistry (drug metabolism & concept of prodrug) correctedMedicinal chemistry (drug metabolism & concept of prodrug) corrected
Medicinal chemistry (drug metabolism & concept of prodrug) corrected
Suny Bisshojit
 

More Related Content

What's hot

What's hot (20)

BIOISOSTERSM
BIOISOSTERSMBIOISOSTERSM
BIOISOSTERSM
 
Medicinal chemistry i
Medicinal chemistry iMedicinal chemistry i
Medicinal chemistry i
 
Analog design medicinal chemistry
Analog design medicinal chemistryAnalog design medicinal chemistry
Analog design medicinal chemistry
 
Drug design
Drug designDrug design
Drug design
 
History of Medicinal Chemistry
History of Medicinal ChemistryHistory of Medicinal Chemistry
History of Medicinal Chemistry
 
Medicinal chemistry
Medicinal chemistry Medicinal chemistry
Medicinal chemistry
 
Rationale of prodrug design and practical considertions of prodrug design
Rationale of prodrug design and practical considertions of prodrug designRationale of prodrug design and practical considertions of prodrug design
Rationale of prodrug design and practical considertions of prodrug design
 
Physicochemical Properties of Drug
Physicochemical Properties of DrugPhysicochemical Properties of Drug
Physicochemical Properties of Drug
 
Medicinal chemistry Basics
Medicinal chemistry BasicsMedicinal chemistry Basics
Medicinal chemistry Basics
 
Combinatorial chemistry
Combinatorial chemistryCombinatorial chemistry
Combinatorial chemistry
 
PRODRUGS
PRODRUGSPRODRUGS
PRODRUGS
 
Medicinal chemistry Basics
Medicinal chemistry BasicsMedicinal chemistry Basics
Medicinal chemistry Basics
 
Hammett parameters
Hammett parametersHammett parameters
Hammett parameters
 
Qsar
QsarQsar
Qsar
 
3. stereochemistry of steroids
3. stereochemistry of steroids3. stereochemistry of steroids
3. stereochemistry of steroids
 
Antibiotics - Medicinal chemistry
Antibiotics - Medicinal chemistry Antibiotics - Medicinal chemistry
Antibiotics - Medicinal chemistry
 
QSAR by hansch analysis
QSAR by hansch analysisQSAR by hansch analysis
QSAR by hansch analysis
 
Medicinal chemistry
Medicinal chemistryMedicinal chemistry
Medicinal chemistry
 
Hansch and Free-Wilson QSAR Models
Hansch and Free-Wilson QSAR ModelsHansch and Free-Wilson QSAR Models
Hansch and Free-Wilson QSAR Models
 
Impurities in API , types and their sources including genotoxic impurities
Impurities in API , types and their sources including genotoxic impuritiesImpurities in API , types and their sources including genotoxic impurities
Impurities in API , types and their sources including genotoxic impurities
 

Viewers also liked

What is medicinal chemistry.ppt
What is medicinal chemistry.pptWhat is medicinal chemistry.ppt
What is medicinal chemistry.ppt
karthik1023
 

Viewers also liked (11)

1 lab physico-chemical_properties_of_drugs[1]
1 lab physico-chemical_properties_of_drugs[1]1 lab physico-chemical_properties_of_drugs[1]
1 lab physico-chemical_properties_of_drugs[1]
 
Medicinal chemistry (drug metabolism & concept of prodrug) corrected
Medicinal chemistry (drug metabolism & concept of prodrug) correctedMedicinal chemistry (drug metabolism & concept of prodrug) corrected
Medicinal chemistry (drug metabolism & concept of prodrug) corrected
 
Physiological factors of drug absorption
Physiological factors of drug absorptionPhysiological factors of drug absorption
Physiological factors of drug absorption
 
medicinal chemistry of Antibiotic
medicinal chemistry of Antibiotic medicinal chemistry of Antibiotic
medicinal chemistry of Antibiotic
 
Physico-chemical Properties Affecting Drug Formulation.
Physico-chemical Properties Affecting Drug Formulation.Physico-chemical Properties Affecting Drug Formulation.
Physico-chemical Properties Affecting Drug Formulation.
 
Parasympatholytics medicinal chemistry b. pharm.
Parasympatholytics medicinal chemistry b. pharm. Parasympatholytics medicinal chemistry b. pharm.
Parasympatholytics medicinal chemistry b. pharm.
 
A Brief History of Pharmacy by Dr.Ankit Srivastava
A Brief History of Pharmacy by Dr.Ankit SrivastavaA Brief History of Pharmacy by Dr.Ankit Srivastava
A Brief History of Pharmacy by Dr.Ankit Srivastava
 
chemicals in medicines
chemicals in medicineschemicals in medicines
chemicals in medicines
 
Pharmacy History
Pharmacy HistoryPharmacy History
Pharmacy History
 
Physicochemical Properties effect on Absorption of Drugs
Physicochemical Properties effect on Absorption of DrugsPhysicochemical Properties effect on Absorption of Drugs
Physicochemical Properties effect on Absorption of Drugs
 
What is medicinal chemistry.ppt
What is medicinal chemistry.pptWhat is medicinal chemistry.ppt
What is medicinal chemistry.ppt
 

Similar to Lecture 1

introductionofpharmacology-141126031620-conversion-gate01.ppt
introductionofpharmacology-141126031620-conversion-gate01.pptintroductionofpharmacology-141126031620-conversion-gate01.ppt
introductionofpharmacology-141126031620-conversion-gate01.ppt
juuisha
 
Intro to pharmacology
Intro to pharmacologyIntro to pharmacology
Intro to pharmacology
Dr Shah Murad
 
General Pharmacology - Final.pptx
General Pharmacology - Final.pptxGeneral Pharmacology - Final.pptx
General Pharmacology - Final.pptx
Obsa2
 

Similar to Lecture 1 (20)

Lecture1 100717171756-phpapp01
Lecture1 100717171756-phpapp01Lecture1 100717171756-phpapp01
Lecture1 100717171756-phpapp01
 
introductionofpharmacology-141126031620-conversion-gate01.ppt
introductionofpharmacology-141126031620-conversion-gate01.pptintroductionofpharmacology-141126031620-conversion-gate01.ppt
introductionofpharmacology-141126031620-conversion-gate01.ppt
 
Bioanalysis significance 12 oct 2022.ppt
Bioanalysis significance 12 oct 2022.pptBioanalysis significance 12 oct 2022.ppt
Bioanalysis significance 12 oct 2022.ppt
 
Introduction of Veterinary pharmacology
Introduction of Veterinary pharmacologyIntroduction of Veterinary pharmacology
Introduction of Veterinary pharmacology
 
Introduction of Veterinary pharmacology Somaliland Dr.Osman Abdulahi Farah
Introduction of Veterinary pharmacology Somaliland Dr.Osman Abdulahi FarahIntroduction of Veterinary pharmacology Somaliland Dr.Osman Abdulahi Farah
Introduction of Veterinary pharmacology Somaliland Dr.Osman Abdulahi Farah
 
Pharmacology
PharmacologyPharmacology
Pharmacology
 
Biopharm review1
Biopharm review1Biopharm review1
Biopharm review1
 
Clinical pharmacology.Basics.
Clinical pharmacology.Basics.Clinical pharmacology.Basics.
Clinical pharmacology.Basics.
 
introductory Medicinal Chemistry.pptx
introductory Medicinal Chemistry.pptxintroductory Medicinal Chemistry.pptx
introductory Medicinal Chemistry.pptx
 
Drug discovery, Design & development basics
Drug discovery, Design & development basicsDrug discovery, Design & development basics
Drug discovery, Design & development basics
 
PHARMACOLGY I-Lecturer 1.pptx
PHARMACOLGY I-Lecturer 1.pptxPHARMACOLGY I-Lecturer 1.pptx
PHARMACOLGY I-Lecturer 1.pptx
 
Drug discovery anthony crasto
Drug discovery anthony crastoDrug discovery anthony crasto
Drug discovery anthony crasto
 
Explore pharmacology
Explore pharmacologyExplore pharmacology
Explore pharmacology
 
Intro to pharmacology
Intro to pharmacologyIntro to pharmacology
Intro to pharmacology
 
general pharmacology
general pharmacologygeneral pharmacology
general pharmacology
 
Computer Aided drug Design and its discovery process
Computer Aided drug Design and its discovery process Computer Aided drug Design and its discovery process
Computer Aided drug Design and its discovery process
 
Pharmacology Theory_Introduction & Routes of Administration.pptx
Pharmacology Theory_Introduction & Routes of Administration.pptxPharmacology Theory_Introduction & Routes of Administration.pptx
Pharmacology Theory_Introduction & Routes of Administration.pptx
 
Drug discovery and development
Drug discovery and developmentDrug discovery and development
Drug discovery and development
 
General Pharmacology - Final.pptx
General Pharmacology - Final.pptxGeneral Pharmacology - Final.pptx
General Pharmacology - Final.pptx
 
FGBGFBNFGGNHNNHNGHNGHNGHNGHNCBVNFHNHGNGHFVFBV
FGBGFBNFGGNHNNHNGHNGHNGHNGHNCBVNFHNHGNGHFVFBVFGBGFBNFGGNHNNHNGHNGHNGHNGHNCBVNFHNHGNGHFVFBV
FGBGFBNFGGNHNNHNGHNGHNGHNGHNCBVNFHNHGNGHFVFBV
 

More from ammar905

Procedural accidents in root canal treatment last one
Procedural accidents in root canal treatment last oneProcedural accidents in root canal treatment last one
Procedural accidents in root canal treatment last one
ammar905
 
The royal college of surgeons
The royal college of surgeonsThe royal college of surgeons
The royal college of surgeons
ammar905
 
20110630021336 mfd exam regulations (june 201
20110630021336 mfd exam regulations (june 20120110630021336 mfd exam regulations (june 201
20110630021336 mfd exam regulations (june 201
ammar905
 
Dental caries
Dental cariesDental caries
Dental caries
ammar905
 
Practice management in dentistry
Practice management in dentistryPractice management in dentistry
Practice management in dentistry
ammar905
 
Removable partial denture
Removable partial dentureRemovable partial denture
Removable partial denture
ammar905
 
Third year lecture 8
Third year lecture 8Third year lecture 8
Third year lecture 8
ammar905
 
Second lec& 3rd
Second lec& 3rdSecond lec& 3rd
Second lec& 3rd
ammar905
 
Medicinal chemistry
Medicinal chemistryMedicinal chemistry
Medicinal chemistry
ammar905
 
Lecture no 4
Lecture no 4Lecture no 4
Lecture no 4
ammar905
 
Lecture 10
Lecture 10Lecture 10
Lecture 10
ammar905
 
Endodontic microbiology, pharos 2009
Endodontic microbiology, pharos 2009Endodontic microbiology, pharos 2009
Endodontic microbiology, pharos 2009
ammar905
 
Orthodontic assessment
Orthodontic assessmentOrthodontic assessment
Orthodontic assessment
ammar905
 
cleft lip & palate
cleft lip & palatecleft lip & palate
cleft lip & palate
ammar905
 
Copy of cleft lip & palate
Copy of cleft lip & palateCopy of cleft lip & palate
Copy of cleft lip & palate
ammar905
 

More from ammar905 (20)

Procedural accidents in root canal treatment last one
Procedural accidents in root canal treatment last oneProcedural accidents in root canal treatment last one
Procedural accidents in root canal treatment last one
 
The royal college of surgeons
The royal college of surgeonsThe royal college of surgeons
The royal college of surgeons
 
20110630021336 mfd exam regulations (june 201
20110630021336 mfd exam regulations (june 20120110630021336 mfd exam regulations (june 201
20110630021336 mfd exam regulations (june 201
 
Dental caries
Dental cariesDental caries
Dental caries
 
Practice management in dentistry
Practice management in dentistryPractice management in dentistry
Practice management in dentistry
 
Removable partial denture
Removable partial dentureRemovable partial denture
Removable partial denture
 
Third year lecture 8
Third year lecture 8Third year lecture 8
Third year lecture 8
 
Second lec& 3rd
Second lec& 3rdSecond lec& 3rd
Second lec& 3rd
 
Medicinal chemistry
Medicinal chemistryMedicinal chemistry
Medicinal chemistry
 
Lecture 5
Lecture 5Lecture 5
Lecture 5
 
Lecture no 4
Lecture no 4Lecture no 4
Lecture no 4
 
Lecture 10
Lecture 10Lecture 10
Lecture 10
 
Lecture 7
Lecture 7Lecture 7
Lecture 7
 
Lecture 6
Lecture 6Lecture 6
Lecture 6
 
Endodontic microbiology, pharos 2009
Endodontic microbiology, pharos 2009Endodontic microbiology, pharos 2009
Endodontic microbiology, pharos 2009
 
Orthodontic assessment
Orthodontic assessmentOrthodontic assessment
Orthodontic assessment
 
Maxillary
MaxillaryMaxillary
Maxillary
 
Maxillary
MaxillaryMaxillary
Maxillary
 
cleft lip & palate
cleft lip & palatecleft lip & palate
cleft lip & palate
 
Copy of cleft lip & palate
Copy of cleft lip & palateCopy of cleft lip & palate
Copy of cleft lip & palate
 

Lecture 1