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Practice Guidelines for the Management
of Electrical Injuries
             Brett Arnoldo, MD,* Matthew Klein, MD† Nicole S. Gibran, MD



There has been increasing emphasis on the develop-                     no history of loss of consciousness, and no other
ment of practice guidelines and validated measure-                     indications for admission (ie, soft-tissue injury),
ments to evaluate surgical practice. Initiatives such as               can be discharged from the emergency room.
the National Surgical Quality Improvement Program                  2. All patients with history of loss of consciousness
(NSQIP) have demonstrated the importance of an                         or documented dysrhythmia either before or af-
outcome-based approach to improving surgical care.                     ter admission to the emergency room should be
The development of guidelines and outcome-based                        admitted for telemetry monitoring. Patients
benchmarks requires established standards of practice                  with ECG evidence of ischemia should be ad-
that should be based on level I data from well-                        mitted and placed on cardiac monitors.
designed prospective randomized trials.                            3. Creatine kinase enzyme levels, including MB
   Electrical burns are potentially devastating injuries               fraction, are not reliable indicators of cardiac
with both short- and long-term sequelae. In 2001, the                  injury after electrical burns and should not be
American Burn Association published a set of practice                  used in decisions regarding patient disposition.
guidelines for various aspects of burn care in the Journal             Insufficient data exists on troponin levels to for-
of Burn Care and Rehabilitation. However, guidelines                   mulate a guideline.
for the management of electrical burns were not in-                Options. Electrical injuries can result in potentially
cluded. Two fundamental—and controversial—issues                fatal cardiac dysrhythmias. The need for cardiac eval-
in the management of electrical burns are cardiac mon-          uation and subsequent cardiac monitoring are critical
itoring and evaluation and treatment of the injured up-         components in electrical burn management. Most pa-
per extremity. We have reviewed and analyzed the avail-         tients who sustain electrical injuries undergo ECG
able literature in an effort to develop practice guidelines     evaluation, and patients with documented dysrhyth-
for these two important issues.                                 mias, cardiac ischemia, or history of loss of conscious-
                                                                ness will be admitted to the hospital for further eval-
SECTION I: CARDIAC MONITORING                                   uation and monitoring. However, the appropriate
AFTER ELECTRICAL INJURIES                                       cardiac diagnostic tests and the indications for hospi-
                                                                tal admission, necessity of cardiac monitoring, and
Recommendations                                                 appropriate duration of cardiac monitoring have not
   Standards. An electrocardiogram (ECG) should                 been well established.
be performed on all patients who sustain electrical
injuries (high and low voltage).
   Guidelines
                                                                OVERVIEW
   1. Children and adults who sustain low-voltage
      electrical injuries, have no ECG abnormalities,           Purpose
                                                                The purpose of this guideline review is to review the cur-
                                                                rent data on practices for diagnosing cardiac injury and
From the *University of Texas Southwestern Medical Center,      indications for cardiac monitoring after electrical injury.
  Parkland Memorial Hospital, Dallas; and †University of
  Washington Burn Center, Harborview Medical Center, Seattle.
Address correspondence to Nicole S. Gibran, MD, University of
  Washington Burn Center, Harborview Medical Center, Box        Users
  359796, 325 9th Avenue, Seattle, WA 98104.
Copyright © 2006 by the American Burn Association.              These guidelines are designed to aid physicians in making
1559-047X/2006                                                  decisions regarding patient disposition, diagnostic tests
DOI: 10.1097/01.BCR.0000226250.26567.4C                         and management of patients following electrical injury.

                                                                                                                      439
Journal of Burn Care & Research
440 Arnoldo et al                                                                                    July/August 2006




Clinical Problem                                           low-voltage and high-voltage injuries, reinforcing the
The potential for development of cardiac dysrhyth-         need for ECG evaluation of all patients. Nonspecific
mia, cardiac arrest, and myocardial damage after elec-     ST-T changes were the most common ECG abnor-
trical injury has been well documented.1–5 Cardiac         mality,2,6,7 and atrial fibrillation was the most com-
dysrhythmias, cardiac standstill, and myocardial in-       mon dysrhythmia.
jury can occur after both low- ( 1000 V) and high-
voltage ( 1000 V) injury. The potential for cardiac        Criteria for Admission
dysrhythmia and injury has prompted routine cardiac        Admission and cardiac monitoring for patients with
evaluation and low threshold for patient admission         history of loss of consciousness, ECG abnormalities,
and of all patients who sustain electrical injury.         or with other indications for admission (ie, TBSA
Whereas obtaining an ECG is a well-established com-        burned, need for extremity monitoring) are standard
ponent of the early evaluation of patients after elec-     practices in all series of electrical injuries reviewed. In
trical injury, the indications for patient admission       addition, the majority of patients with low-voltage
and appropriate duration of cardiac monitoring             injuries and normal ECG are discharged home from
have been less clear. Traditionally, patients with         the emergency room without complication. The
low-voltage injuries who have normal ECGs and no           safety of this practice also was confirmed in two series
history of loss of consciousness are discharged from       of pediatric patients.1,8 The possible exceptions in-
the hospital. However, appropriate management of           clude patients with other injuries that require hospi-
patients who sustain high-voltage injuries has not         talization or children with an oral burn that would
been well defined. Generally, patients who have a          require monitoring for labial artery bleeding.
history of loss of consciousness, ECG abnormalities,          Virtually all patients with high-voltage injuries are
or have injuries that would otherwise require admis-       admitted for cardiac monitoring; however, it is un-
sion are admitted to the hospital and are placed on        clear whether this step is necessary. With increasing
telemetry monitors. There are several issues related to    emphasis on cost-effectiveness, the routine admission
the cardiac evaluation and monitoring that need to be      of all patients with high-voltage injury must be ques-
addressed: 1) Should all patients with high-voltage        tioned. Hunt,9 Bailey et al,1 and Arrowsmith et al10
electrical injuries be admitted to the hospital, even if   reported that all cardiac irregularities were evident
there is no evidence of cardiac abnormality? 2) What       either on admission to the emergency room or within
is the role of cardiac enzymes in the evaluation and       several hours of hospitalization and in 1986, Purdue
management of electrical injuries? 3) How long             and Hunt5 reported that no serious arrhythmias oc-
should patients be monitored on telemetry?                 curred in any patient who a normal ECG on admis-
                                                           sion. Taken together, these studies suggest that a
                                                           negative initial evaluation could obviate the need for
Process
                                                           hospital admission solely for cardiac monitoring.
A Medline search was conducted of all available liter-     However, these were observations based on retro-
ature from 1966 to 2004 using the key words elec-          spective data and are inadequate to form the basis of
trical, burns, cardiac, monitoring. In addition, several   a practice guideline. On the basis of their findings,
articles were not identified in the Medline search but     Purdue and Hunt5 generated the following set of
were referenced in the articles reviewed and were          admission criteria for electrically injured patients: 1)
found to be relevant: a total of 27 articles were re-      loss of consciousness or cardiac arrest in the field; 2)
viewed and found to be relevant.                           documented cardiac arrhythmia in the field; 3) ab-
   References were classified as Class 1 evidence (pro-    normal ECG; or 4) a separate indication for admis-
spective, randomized, controlled trials); Class II evi-    sion. They applied these criteria prospectively to 10
dence (prospective or retrospective studies based on       consecutive patients and reported no complications.
clearly reliable data); Class III evidence (evidence       This study is the first to investigate not routinely
provided by clinical series, comparative studies, case     monitoring patients who sustained high-voltage
reviews or reports); or as a technology assessment (a      injuries. However, this series is too small to affect
study that examined the utility/reliability of a partic-   practice.
ular technology).                                             One study suggested that presentation of cardiac
                                                           abnormalities could be delayed. Jensen et al11 re-
Scientific Foundation                                      ported three patients with a delay in the onset of
   Cardiac Abnormalities. All studies reviewed con-        symptoms after low-voltage (two patients) and high-
firmed that cardiac abnormalities—including dys-           voltage (one patient) injuries. All presented to the
rhythmias and myocardial damage— occur after both          emergency room only after they developed chest pain
Journal of Burn Care & Research
Volume 27, Number 4                                                                               Arnoldo et al   441



and palpitations. However, none of the patients had         high-voltage injuries and normal ECGs. The two
ECGs or any sort of evaluation at the time of injury        studies that addressed this question have population
and, therefore, this study does not provide substan-        sizes that are too small to support changes in practice.
tive evidence of truly late dysrhythmia presentation.       Future prospective and randomized studies (as de-
                                                            scribed herein) are needed to effectively establish
Duration of Monitoring                                      practice guidelines. In addition, there is inadequate
No published studies have directly studied the appro-       evidence to formulate guidelines for the duration of
priate duration of telemetry monitoring after injury.       monitoring for patients with ECG abnormalities.
Several series reported monitoring for 24 hours after          Sufficient data are available to conclude that
admission if there were no ECG abnormalities on             CK-MB is an unreliable diagnostic test for cardiac
admission or monitoring for 24 hours after resolution       injury after electrical injury. The presence of skeletal
of dysrhythmias.1,8,12 Arrowsmith et al10 reported          muscle injury in these patients confounds the results
that all patients with dysrhythmias resolved within         of this laboratory test. No studies identified in this
48 hours of admission either spontaneously or with          review examined the specificity and utility of troponin
pharmacologic intervention. However, there are no           levels in determining cardiac injury.
data available to formulate appropriate management
guidelines for this issue.                                  Key Issues for Further Evaluation
                                                              1. Utility of troponin: CK and CK-MB not specific
Utility of Creatine Kinase                                       for cardiac muscle. Insufficient data exists eval-
Creatine kinase levels frequently are obtained after             uating the utility of troponin in assessing cardiac
electrical injury. CK has long been used as an indica-           injury.
tor of muscle injury and can help in determining the          2. Duration of monitoring: insufficient data exists
extent of extremity muscle injury. The MB subunit                to determine the optimal duration of telemetry
has been reported to be more specific for myocardium             monitoring after electrical injury for patients
and, therefore, has been used to evaluate cardiac in-            who have abnormal ECGs or history of loss of
jury after electrical injury. Only one study reported a          consciousness. There have been no studies that
reliable correlation between serum CK-MB levels and              directly examined this specific question.
cardiac injury. Chandra et al6 reported that the time         3. Admission for high-voltage injuries: insufficient
course of the MB fraction increase and decrease was a            data exists to establish guidelines for whether to
reliable indicator of cardiac ischemia. However, this            admit patients who sustain high-voltage injuries
study does not correlate the elevated enzyme levels with         but have normal ECG’s and no history of loss of
any other study of cardiac injury. Conversely, the evi-          consciousness. The available data suggest that
dence of poor or questionable correlation was quite              these patients could be discharged but further,
strong. Several studies demonstrated that CK-MB                  prospective evaluation is required.
levels poorly predict cardiac injury and that the
elevated enzyme levels likely result from noncar-           Evidentiary Table
diac muscle injury.7,13–15 Housinger et al7 sug-
                                                            Studies on the practices of cardiac evaluation and
gested that positive MB fractions in the absence of ECG
                                                            monitoring are summarized in Table 1.
findings should be interpreted with caution because
they may not signify cardiac injury. Given the paucity of
evidence supporting the utility of CK-MB levels, this       II. EVALUATION AND MANAGEMENT
laboratory value should not be used as a diagnostic         OF THE UPPER EXTREMITY
criterion for cardiac injury after electrical injury.
                                                            Recommendations
                                                               Standards. Insufficient data exist to support a
SUMMARY                                                     treatment standard for this topic.
The current practices of admitting patients with his-          Guidelines
tory of loss of consciousness, documented dysrhyth-            1. Patients with high-voltage electrical injury to
mia in the field, or ECG abnormalities are well                   the upper extremity should be referred to spe-
supported in the literature. Similarly, discharging               cialized burn centers experienced with these in-
patients from the emergency room with low-voltage                 juries as per American Burn Association referral
injuries and normal ECGs is well established. How-                criteria.
ever, few data are available to support establishment          2. Indications for surgical decompression include
of guidelines for the management of patients with                 progressive neurologic dysfunction, vascular
Journal of Burn Care & Research
442 Arnoldo et al                                                                                                          July/August 2006



Table 1. Evidence table
     Reference                    Study Description                   Data Class                    Conclusions/Comments

Ahrenholz et al,    Retrospective study of 125 patients                  II        Demonstrated that there is a poor correlation between
  198813              admitted with electrical injuries                             elevated CK-MB levels and cardiac injury
Arrowsmith et al,   Retrospective study of 145 patients                  II        All patients with cardiac complications had them at the
  199710              admitted with electrical injuries to                           time of admission. Patients with normal ECG and no
                      determine incidence of cardiac                                 loss of consciousness do not require admission for
                      complications                                                  cardiac monitoring
Bailey et al,       Retrospective review of 141 children                 II        Children with normal ECG and low voltage injuries do
  199543              admitted to the emergency department                          not require cardiac monitoring. Authors also suggested
                      with household electrical injuries                            that ECG is not indicated for children with low-voltage
                                                                                    injuries, no loss of consciousness, no tetany, no water
                                                                                    contact, and no current crossing the heart region
Bailey et al,       Prospective evaluation of a set of admission         II        Guidelines for admission were used in the majority of
  20001               guidelines after electrical injury.                           cases. According to the guidelines, all patients with
                      Guidelines were applied to a total of 224                     high-voltage injuries were admitted, as were patients
                      patients                                                      with low-voltage injuries with ECG abnormalities, past
                                                                                    cardiac history, water contact, and tetany
Chandra et al,      Prospective evaluation of 34 patients                II        Time course of CK-MB elevation in patients with
 19906                admitted with high-voltage electrical                          electrical injuries suggests that it is cardiac in etiology.
                      injuries to determine predictors of                            ECG may not be reliable for diagnosing myocardial
                      myocardial damage                                              damage
Cunningham,         Retrospective study of 70 patients admitted          II        Discharged all patients with low-voltage injuries who are
 199144               with electrical injury                                         asymptomatic and had normal ECG without
                                                                                     complication
Guinard et al,      Prospective evaluation of 10 patients                III       Demonstrated poor reliability of CK-MB to identify
 198715               admitted with electrical injuries                             cardiac injuries
Housinger et al,    Prospective study of 16 patients to determine        III       Demonstrated poor correlation between elevation of
 19857                incidence of possible myocardial damage                       CK-MB levels and ECG abnormalities. Pyrophosphate
                      following electrical burn                                     scans were used as diagnostic standard for cardiac
                                                                                    injury
Hunt et al,         Retrospective review of 102 patients with            II        All cardiac abnormalities were evident either on
 19809                high-voltage injuries                                          admission of within several hours of hospitalization
Jensen et al,       Three case reports of late presentation of           III       Three patients with late presentation of cardiac
  198711              cardiac abnormalities after electrical injury                  abnormalities. However, none of the patients were
                                                                                     evaluated immediately after injury
Lewin et al,        Case report of 19-year old patient with              III       Demonstrated correlation of CK-MB levels with ECG
  19834               myocardial injury after electrical injury                     abnormalities and myocardial injury
Purdue and Hunt,    Retrospective study of 48 patients admitted          II        Designed a protocol for determining which patients
  19865               with high-voltage injuries. On the basis of                   should be admitted following high voltage injury. No
                      these findings, a prospective study of 10                     complications following discharge of patients with high
                      patients applying guidelines for admission                    voltage injuries and no other indications for
                                                                                    admission.Comment: First study to demonstrate safety of
                                                                                    discharging patients with high-voltage injuries and
                                                                                    normal ECGs. However, small group of patients studied
Wallace et al,      Retrospective study of 35 pediatric patients         II        Children with low-voltage injuries and normal ECGs can
 19958                with both low and high voltage injuries                       be discharged. However, all patients with high-voltage
                                                                                    injuries were admitted and monitored
Zubair et al,       Retrospective study of 127 pediatric patients        II        Recommend 4 hours of monitoring for all patients before
  199712              with low- and high-voltage injuries                            discharge and admission of all patients with high-
                                                                                     voltage injuries, loss of consciousness, or ECG
                                                                                     abnormalities
Journal of Burn Care & Research
Volume 27, Number 4                                                                               Arnoldo et al   443



      compromise, increased compartment pressure,           “compartment pressure,” “Doppler flow meter,”
      and systemic clinical deterioration from sus-         “technetium 99m pyrophosphate,” “infrared pho-
      pected ongoing myonecrosis. Decompression             toplethysmography,” and “burn injury” was per-
      includes forearm fasciotomy and assessment of         formed, and relevant articles were reviewed. Stud-
      muscle compartments. The decision to include          ies of patients with lower-extremity injuries were
      a carpal tunnel release should be made on a           included because of the scarcity of data involving ex-
      case-by-case basis.                                   clusively the upper extremity. An attempt was made
   Options. There are several methods to evaluate the       however to analyze the data involving the upper ex-
injured extremity. Compartment pressures may be             tremity exclusively where possible.
measured as an adjunct to clinical examination. Pres-
sures greater than 30 mm Hg, or tissue pressure             Scientific Foundation
reaching within 10 to 20 mm Hg of diastolic pres-           Electrical injuries, including lightning strikes, should
sure, may be used as evidence of increased compart-         be referred to a specialized burn center as per Amer-
ment pressure and potential deep-tissue injury, indi-       ican Burn Association criteria.18 Many surgeons ad-
cating the need for surgical decompression in the           vocate immediate surgical exploration (usually within
appropriate clinical setting. Technetium-99m pyro-          the first 24 hours), and decompression of patients
phosphate scan may be used as an adjunct to clinical        with high-voltage electrical injuries.19,20 –32 Early ex-
examination at centers experienced with this technol-       ploration, fasciotomy, and debridment are followed
                                                                                            ´
ogy. Doppler flow meter can be used as an adjunct to        by serial debridment of necrotic tissue and subse-
                                                                         ´
assess extremity perfusion. It should not be relied on      quent closure. These studies are somewhat difficult to
as the sole indicator of deep-tissue viability and ade-     interpret; however, because of the differences in the
quate perfusion.                                            degree of injury no prospective, randomized, con-
                                                            trolled trials evaluating immediate exploration have
                                                            been performed. The rational for this aggressive ap-
OVERVIEW                                                    proach relates to thermal mechanics. Joule’s law de-
Purpose                                                     fining the amount of power (heat) delivered to an
                                                            object:
The purpose of this guideline is to review the princi-
                                                               Power (J-Joule) I2 (Current) times R (Resistance).
ples of monitoring and treatment of high-voltage
                                                               Accordingly, deep muscle necrosis can occur in the
electrical burn injury to the upper extremity. The up-
                                                            muscle adjacent to bone, which has a high resis-
per extremity is commonly injured after high-voltage
                                                            tance.33–35 Failure to perform adequate fasciotomy
electrical and carries with it a high rate of morbidity.
                                                            and to evaluate all muscle compartments may lead to
                                                            misdiagnosis of deep thermal injury.20 This approach
Clinical Problem                                            however, commits the patient to several operations
Burns resulting from high-voltage electric current          and may prolong hospital stay and morbidity.
( 1000 V) often are associated with a greater degree           In the d’Amato20 series, six patients underwent
of deep-tissue injury than is initially appreciated. As a   emergency exploratory surgery and amputation for
result these rather infrequent injuries, which make up      obvious necrotic extremities, followed by serial de-   ´
only 3% to 12% of burn center admissions,16 are as-         bridment. No patient required an amputation for
sociated with high amputation rates and greater use         misdiagnosed deep muscle necrosis. However,
of resources than comparable %TBSA cutaneous                missed injury was present in two patients, who re-
burns.6,10,17 Unnecessary exploration can increase          quired further surgical intervention, although neither
morbidity, length of stay, and the use of scarce re-        required amputation because of the missed injury.
sources. Delayed exploration and decompression in           Parshley’s series evaluated 41 patients with 27 ex-
the compromised extremity, however, may result in           tremities explored. Amputation rate was 40% with 10
increased amputation rates along with increased or-         extremities salvaged, which the authors attribute to
gan failure and mortality.31                                early aggressive operative intervention. Haberal’s se-
                                                            ries of 94 patients had an amputation rate of 43%. The
Process                                                     authors attributed this high amputation rate in part
A Medline search from 1966 to the present was used          because of a delay in surgical exploration as a result of
to evaluate monitoring and the need for early explo-        patients being transferred from nonspecialized facili-
ration and fasciotomy in electrical injury to the ex-       ties. Achauer et al21 reported a series of 22 patients
tremity. A search for the key words, “electrical in-        with an amputation rate of 40%. They recommend
jury,” “fasciotomy,” “compartment syndrome,”                “extensive debridement of all damaged tissue and ex-
Journal of Burn Care & Research
444 Arnoldo et al                                                                                                         July/August 2006



Table 2. Evidentiary table: high-voltage electric injury to upper extremity
     Reference                    Description                   Data Class                             Comments

Quinby et al,       Retrospective review of 44 patients           II         In conductive burns with entrance site in hand, incision was
 197825               divided into 22 with electric arc and                    carried from hand to interconnect the arc burns at wrist,
                      22 with flow of current                                  elbow, and shoulder. Fasciotomies done if muscle
                                                                               discolored, or tense, transverse carpal ligament release done.
                                                                               Amputation rate 68%
Luce et al,         Retrospective review of 31 patients           II         Fasciotomy and wound exploration and debridement within
  198426                                                                       24 hours of admission Amputation rate 35.5%
Parshley et al,     Retrospective review 41 patients with         II         Early fasciotomy in patients with passage of current
  198522              passage of current                                       Amputation rate 40%
Achauer et al,      Retrospective analysis of electric injury     II         Extensive debridement and compartment release almost always
  199421              of the hand in 22 patients                               done on day of injury. Amputation rate 40%
Mann et al,         Retrospective review 62 patients with         II         Fasciotomy indications: severe pain and loss of arterial
  199631              high voltage upper extremity injury                      Doppler signal, neurologic deterioration, systemic clinical
                                                                               deterioration from suspected ongoing myonecrosis. Carpal
                                                                               tunnel release performed along with fasciotomy. 16 of 62
                                                                               patients (25.8%) required emergent decompression within
                                                                               first 24 hours. Amputation rate in these patients 45%.
                                                                               Overall amputation rate 10%
Yowler et al,       Retrospective chart review 51 patients        III        Indications for fasciotomy: Elevated muscle compartment
  199832              with high voltage injuries to the                        pressure greater than 30 mmHg. Neurologic dysfunction,
                      upper and lower extremity                                vascular compromise, extensive deep burn. 11 patients
                                                                               under went 18 major amputations
DiVincenti et al,   Retrospective review of 65 electrical         III        Early fasciotomy indicated for cyanosis of distal uninjured skin,
  196924              injuries over 17 years, upper and                        impaired capillary refill, progressive neurologic change,
                      lower extremities included, high and                     brawny edema and muscle compartment tightness.
                      low voltage injuries included                            Amputation rate 32.5%
Butler et al,       Retrospective review of 182 cases over        III        40 patients underwent an average of 5 operations. Marked
  197723              twenty years. Includes high voltage                      swelling of the wrist and hand, the volar carpal ligament is
                      and low voltage injuries                                 divided at time of extremity fasciotomy. Amputation rate
                                                                               65%
Mann et al,         Series of 8 patients with high voltage        III        Early decompression fasciotomy and debridement.
 197527               injury. Includes upper and lower                         Amputations done on at least one extremity in all patients
                      extremities
D’Amato et al,      Series of 6 patients with high voltage        III        Mandatory exploration of forearm and hand compartments
  199420              upper extremity injury                                   following initial resuscitation. All patients required
                                                                               amputation
Hussmann et al,     Retrospective evaluation of 38 high           III        Early serial debridement of obviously necrotic tissue,
 199545               voltage injuries. Included upper and                     fasciotomy including carpal tunnel release for “compartment
                      lower extremity                                          syndrome” 39 amputations performed in 38 patients
Saffle et al,       Evaluation of wick catheter to measure        II         Recommended routine measurement of IMP as a more
  198035              intramuscular compartment                                sensitive than Doppler pulses, and use of a threshold value
                      pressures (IMP) in 31 extremities in                     of 30 mmHg for performance of escharotomy
                      18 patients, compared with clinical
                      and Doppler findings
Moylan et al,       Prospective evaluation of ultrasonic          II         Escharotomy is indicated when Doppler flow is absent in distal
 197136               flowmeter to assess circulatory                          arteries or arches. Note: This paper documents that Doppler
                      changes in 60 limbs in 24 patients                       pulses can be present in the face of clinical evidence of tissue
                      with circumferential burns                               compression and ischemia
Salisbury et al,    Evaluated post-mortem intrinsic               II/III     Muscle ischemia or necrosis can occur with intact pulses and even
  197437              muscle biopsies following extremity                      following escharotomy. Note: since this was a post-mortem
                      burns. Presence of necrosis was                          study, tissue necrosis may have been a non specific finding
                      similar in patients with (72.2%) and
                      without (66%) escharotomies
                                                                                                                                  (Continued)
Journal of Burn Care & Research
Volume 27, Number 4                                                                                                  Arnoldo et al   445



Table 2. (Continued)
    Reference                     Description                 Data Class                            Comments

Smith et al,       Prospective evaluation of infrared            III       Advocated use of PPG as a noninvasive method of assessing
  198438             photoplethysmography (PPG) to                           vascular compromise. This study supports an IMP 30 mm
                     evaluate vascular status in burned                      Hg as an appropriate threshold for escharotomy in burned
                     extremities and compared with IMP,                      extremities
                     Doppler, and muscle blood flow
                     (MBF). PPG correlated well with
                     IMP and MBF, but poorly with
                     Doppler with changes noted with
                     IMP 30 mm Hg
Chen et al,        High resolution color and pulse               III       Different tissue found to have differing degree of injury.
 200339             Doppler ultrasonography used to                          Concluded that ultrasound could demonstrate morphologic
                    determine burn wound area in 12                          changes in subcutaneous tissue, muscle, and blood vessels
                    patients with deep electrical injury                     after deep electric injury
Hunt et al,        Technetium-99 m pyrophosphate scans           II        Location and extent of muscle injury was correctly ascertained
 197940              performed in 14 patients with high                      preoperatively in all patients
                     voltage electrical injury. Scans were
                     performed between first and fifth day
                     post injury
Affleck et al,     Retrospective review of computerized          III       Revealed a sensitivity of 94% and specificity of 100% showing
  200141             registry identified 11 patients who                     demarcation between viable and nonviable tissue, confirmed
                     underwent Pyrophosphate (PyP)                           at operation
                     scan. Eight patients had high voltage
                     electrical injury, one had frostbite,
                     and two had soft-tissue infection
Hammond et al,     Early scanning (within 3 days of injury)      II        Compared to control group of 17 patients treated without
 199442              with PyP in 19 limbs in 15 patients                    PyP scan, the scan was not associated with reduced length
                     with electrical injury. Sensitivity of                 of stay, or with decreased number of surgical procedures
                     75% and specificity of 100%




tensive compartment release done as an emergency                       putation was ultimately required in 10% of the ex-
(almost always on the day of injury).” Luce reported                   tremities. Extremities that were not decompressed
a series of 31 patients with an extremity amputation                   immediately did not require amputation. The ampu-
rate of 35.5% who “were taken to the operating room                    tation rate for those patients requiring immediate sur-
within 24 hours of admission.” In the DiVincenti et                    gical decompression was 45%. This amputation rate is
al24 series of 65 patients, there was an amputation rate               similar to previous studies, which appear to include
of 32.5%. There are no studies that specifically eval-                 patients with lesser degree of injury. In the series from
uated the impact of timing on treatment outcome.                       the Army Institute of Surgical research,32 51 patients
   Some recent literature has supported a more selec-                  with high-voltage injury were managed selectively.
tive approach to management may reduce the num-                        Indications for operative intervention were evidence
ber of operative interventions and subsequently the                    of neurologic dysfunction, vascular compromise, ex-
morbidity of high voltage electrical injury.31,32 Mann                 tensive deep burn, or increased muscle compartment
et al31 followed a selective management algorithm for                  pressures (repeated measurements 30 mm Hg). A
upper-extremity high-voltage electrical injury. Indi-                  total of 11 patients (21.6%) underwent 18 major ex-
cations for surgical decompression included extrem-                    tremity amputations.
ities that exhibited progressive peripheral nerve dys-                    No precedent exists in the literature for measuring
function, clinical manifestations of compartment                       compartment pressures in the setting of high-voltage
syndrome, or injury sufficient to cause difficulty in                  upper-extremity electrical injury. Some surgeons ad-
resuscitating the patient. Sixty-two patients had a to-                vocate their use, however, on the basis of the ortho-
tal of 100 upper-extremity injuries. Early (within 24                  pedic and vascular literature.33,34 Measurement of
hours of admission), surgical decompression was re-                    compartment pressures in circumferential extremity
quired in 22% of injured upper extremities. An am-                     burn wounds has been recommended by Saffle et al.35
Journal of Burn Care & Research
446 Arnoldo et al                                                                                        July/August 2006



A wick-catheter technique was used to measure intra-      resolution ultrasound, may add much-needed clarity
muscular pressures. A threshold of 30 mm Hg was an        to this clinical problem.
indication for escharotomy (based on vascular com-           Surgical Management. Prospective randomized
partment syndrome literature). Whether or not this        studies that evaluate immediate vs expectant debrid-
                                                                                                        ´
can be extrapolated to include electric injury is un-     ment using well-defined criteria would be useful in
clear. In addition, Moylan et al36 showed that ultra-     defining guidelines for surgical management of the
sonic (Doppler flow meter) signal from the distal ar-     injured extremity.
teries and palmar arch was a more sensitive indicator        Evidentiary Table. Table 2 summarizes research
of perfusion than clinical palpation. Salisbury37 dem-    on the monitoring and treatment of high-voltage up-
onstrated, however, that this objective measure of        per-extremity injury.
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Practice guidelines for the management electrical

  • 1. Practice Guidelines for the Management of Electrical Injuries Brett Arnoldo, MD,* Matthew Klein, MD† Nicole S. Gibran, MD There has been increasing emphasis on the develop- no history of loss of consciousness, and no other ment of practice guidelines and validated measure- indications for admission (ie, soft-tissue injury), ments to evaluate surgical practice. Initiatives such as can be discharged from the emergency room. the National Surgical Quality Improvement Program 2. All patients with history of loss of consciousness (NSQIP) have demonstrated the importance of an or documented dysrhythmia either before or af- outcome-based approach to improving surgical care. ter admission to the emergency room should be The development of guidelines and outcome-based admitted for telemetry monitoring. Patients benchmarks requires established standards of practice with ECG evidence of ischemia should be ad- that should be based on level I data from well- mitted and placed on cardiac monitors. designed prospective randomized trials. 3. Creatine kinase enzyme levels, including MB Electrical burns are potentially devastating injuries fraction, are not reliable indicators of cardiac with both short- and long-term sequelae. In 2001, the injury after electrical burns and should not be American Burn Association published a set of practice used in decisions regarding patient disposition. guidelines for various aspects of burn care in the Journal Insufficient data exists on troponin levels to for- of Burn Care and Rehabilitation. However, guidelines mulate a guideline. for the management of electrical burns were not in- Options. Electrical injuries can result in potentially cluded. Two fundamental—and controversial—issues fatal cardiac dysrhythmias. The need for cardiac eval- in the management of electrical burns are cardiac mon- uation and subsequent cardiac monitoring are critical itoring and evaluation and treatment of the injured up- components in electrical burn management. Most pa- per extremity. We have reviewed and analyzed the avail- tients who sustain electrical injuries undergo ECG able literature in an effort to develop practice guidelines evaluation, and patients with documented dysrhyth- for these two important issues. mias, cardiac ischemia, or history of loss of conscious- ness will be admitted to the hospital for further eval- SECTION I: CARDIAC MONITORING uation and monitoring. However, the appropriate AFTER ELECTRICAL INJURIES cardiac diagnostic tests and the indications for hospi- tal admission, necessity of cardiac monitoring, and Recommendations appropriate duration of cardiac monitoring have not Standards. An electrocardiogram (ECG) should been well established. be performed on all patients who sustain electrical injuries (high and low voltage). Guidelines OVERVIEW 1. Children and adults who sustain low-voltage electrical injuries, have no ECG abnormalities, Purpose The purpose of this guideline review is to review the cur- rent data on practices for diagnosing cardiac injury and From the *University of Texas Southwestern Medical Center, indications for cardiac monitoring after electrical injury. Parkland Memorial Hospital, Dallas; and †University of Washington Burn Center, Harborview Medical Center, Seattle. Address correspondence to Nicole S. Gibran, MD, University of Washington Burn Center, Harborview Medical Center, Box Users 359796, 325 9th Avenue, Seattle, WA 98104. Copyright © 2006 by the American Burn Association. These guidelines are designed to aid physicians in making 1559-047X/2006 decisions regarding patient disposition, diagnostic tests DOI: 10.1097/01.BCR.0000226250.26567.4C and management of patients following electrical injury. 439
  • 2. Journal of Burn Care & Research 440 Arnoldo et al July/August 2006 Clinical Problem low-voltage and high-voltage injuries, reinforcing the The potential for development of cardiac dysrhyth- need for ECG evaluation of all patients. Nonspecific mia, cardiac arrest, and myocardial damage after elec- ST-T changes were the most common ECG abnor- trical injury has been well documented.1–5 Cardiac mality,2,6,7 and atrial fibrillation was the most com- dysrhythmias, cardiac standstill, and myocardial in- mon dysrhythmia. jury can occur after both low- ( 1000 V) and high- voltage ( 1000 V) injury. The potential for cardiac Criteria for Admission dysrhythmia and injury has prompted routine cardiac Admission and cardiac monitoring for patients with evaluation and low threshold for patient admission history of loss of consciousness, ECG abnormalities, and of all patients who sustain electrical injury. or with other indications for admission (ie, TBSA Whereas obtaining an ECG is a well-established com- burned, need for extremity monitoring) are standard ponent of the early evaluation of patients after elec- practices in all series of electrical injuries reviewed. In trical injury, the indications for patient admission addition, the majority of patients with low-voltage and appropriate duration of cardiac monitoring injuries and normal ECG are discharged home from have been less clear. Traditionally, patients with the emergency room without complication. The low-voltage injuries who have normal ECGs and no safety of this practice also was confirmed in two series history of loss of consciousness are discharged from of pediatric patients.1,8 The possible exceptions in- the hospital. However, appropriate management of clude patients with other injuries that require hospi- patients who sustain high-voltage injuries has not talization or children with an oral burn that would been well defined. Generally, patients who have a require monitoring for labial artery bleeding. history of loss of consciousness, ECG abnormalities, Virtually all patients with high-voltage injuries are or have injuries that would otherwise require admis- admitted for cardiac monitoring; however, it is un- sion are admitted to the hospital and are placed on clear whether this step is necessary. With increasing telemetry monitors. There are several issues related to emphasis on cost-effectiveness, the routine admission the cardiac evaluation and monitoring that need to be of all patients with high-voltage injury must be ques- addressed: 1) Should all patients with high-voltage tioned. Hunt,9 Bailey et al,1 and Arrowsmith et al10 electrical injuries be admitted to the hospital, even if reported that all cardiac irregularities were evident there is no evidence of cardiac abnormality? 2) What either on admission to the emergency room or within is the role of cardiac enzymes in the evaluation and several hours of hospitalization and in 1986, Purdue management of electrical injuries? 3) How long and Hunt5 reported that no serious arrhythmias oc- should patients be monitored on telemetry? curred in any patient who a normal ECG on admis- sion. Taken together, these studies suggest that a negative initial evaluation could obviate the need for Process hospital admission solely for cardiac monitoring. A Medline search was conducted of all available liter- However, these were observations based on retro- ature from 1966 to 2004 using the key words elec- spective data and are inadequate to form the basis of trical, burns, cardiac, monitoring. In addition, several a practice guideline. On the basis of their findings, articles were not identified in the Medline search but Purdue and Hunt5 generated the following set of were referenced in the articles reviewed and were admission criteria for electrically injured patients: 1) found to be relevant: a total of 27 articles were re- loss of consciousness or cardiac arrest in the field; 2) viewed and found to be relevant. documented cardiac arrhythmia in the field; 3) ab- References were classified as Class 1 evidence (pro- normal ECG; or 4) a separate indication for admis- spective, randomized, controlled trials); Class II evi- sion. They applied these criteria prospectively to 10 dence (prospective or retrospective studies based on consecutive patients and reported no complications. clearly reliable data); Class III evidence (evidence This study is the first to investigate not routinely provided by clinical series, comparative studies, case monitoring patients who sustained high-voltage reviews or reports); or as a technology assessment (a injuries. However, this series is too small to affect study that examined the utility/reliability of a partic- practice. ular technology). One study suggested that presentation of cardiac abnormalities could be delayed. Jensen et al11 re- Scientific Foundation ported three patients with a delay in the onset of Cardiac Abnormalities. All studies reviewed con- symptoms after low-voltage (two patients) and high- firmed that cardiac abnormalities—including dys- voltage (one patient) injuries. All presented to the rhythmias and myocardial damage— occur after both emergency room only after they developed chest pain
  • 3. Journal of Burn Care & Research Volume 27, Number 4 Arnoldo et al 441 and palpitations. However, none of the patients had high-voltage injuries and normal ECGs. The two ECGs or any sort of evaluation at the time of injury studies that addressed this question have population and, therefore, this study does not provide substan- sizes that are too small to support changes in practice. tive evidence of truly late dysrhythmia presentation. Future prospective and randomized studies (as de- scribed herein) are needed to effectively establish Duration of Monitoring practice guidelines. In addition, there is inadequate No published studies have directly studied the appro- evidence to formulate guidelines for the duration of priate duration of telemetry monitoring after injury. monitoring for patients with ECG abnormalities. Several series reported monitoring for 24 hours after Sufficient data are available to conclude that admission if there were no ECG abnormalities on CK-MB is an unreliable diagnostic test for cardiac admission or monitoring for 24 hours after resolution injury after electrical injury. The presence of skeletal of dysrhythmias.1,8,12 Arrowsmith et al10 reported muscle injury in these patients confounds the results that all patients with dysrhythmias resolved within of this laboratory test. No studies identified in this 48 hours of admission either spontaneously or with review examined the specificity and utility of troponin pharmacologic intervention. However, there are no levels in determining cardiac injury. data available to formulate appropriate management guidelines for this issue. Key Issues for Further Evaluation 1. Utility of troponin: CK and CK-MB not specific Utility of Creatine Kinase for cardiac muscle. Insufficient data exists eval- Creatine kinase levels frequently are obtained after uating the utility of troponin in assessing cardiac electrical injury. CK has long been used as an indica- injury. tor of muscle injury and can help in determining the 2. Duration of monitoring: insufficient data exists extent of extremity muscle injury. The MB subunit to determine the optimal duration of telemetry has been reported to be more specific for myocardium monitoring after electrical injury for patients and, therefore, has been used to evaluate cardiac in- who have abnormal ECGs or history of loss of jury after electrical injury. Only one study reported a consciousness. There have been no studies that reliable correlation between serum CK-MB levels and directly examined this specific question. cardiac injury. Chandra et al6 reported that the time 3. Admission for high-voltage injuries: insufficient course of the MB fraction increase and decrease was a data exists to establish guidelines for whether to reliable indicator of cardiac ischemia. However, this admit patients who sustain high-voltage injuries study does not correlate the elevated enzyme levels with but have normal ECG’s and no history of loss of any other study of cardiac injury. Conversely, the evi- consciousness. The available data suggest that dence of poor or questionable correlation was quite these patients could be discharged but further, strong. Several studies demonstrated that CK-MB prospective evaluation is required. levels poorly predict cardiac injury and that the elevated enzyme levels likely result from noncar- Evidentiary Table diac muscle injury.7,13–15 Housinger et al7 sug- Studies on the practices of cardiac evaluation and gested that positive MB fractions in the absence of ECG monitoring are summarized in Table 1. findings should be interpreted with caution because they may not signify cardiac injury. Given the paucity of evidence supporting the utility of CK-MB levels, this II. EVALUATION AND MANAGEMENT laboratory value should not be used as a diagnostic OF THE UPPER EXTREMITY criterion for cardiac injury after electrical injury. Recommendations Standards. Insufficient data exist to support a SUMMARY treatment standard for this topic. The current practices of admitting patients with his- Guidelines tory of loss of consciousness, documented dysrhyth- 1. Patients with high-voltage electrical injury to mia in the field, or ECG abnormalities are well the upper extremity should be referred to spe- supported in the literature. Similarly, discharging cialized burn centers experienced with these in- patients from the emergency room with low-voltage juries as per American Burn Association referral injuries and normal ECGs is well established. How- criteria. ever, few data are available to support establishment 2. Indications for surgical decompression include of guidelines for the management of patients with progressive neurologic dysfunction, vascular
  • 4. Journal of Burn Care & Research 442 Arnoldo et al July/August 2006 Table 1. Evidence table Reference Study Description Data Class Conclusions/Comments Ahrenholz et al, Retrospective study of 125 patients II Demonstrated that there is a poor correlation between 198813 admitted with electrical injuries elevated CK-MB levels and cardiac injury Arrowsmith et al, Retrospective study of 145 patients II All patients with cardiac complications had them at the 199710 admitted with electrical injuries to time of admission. Patients with normal ECG and no determine incidence of cardiac loss of consciousness do not require admission for complications cardiac monitoring Bailey et al, Retrospective review of 141 children II Children with normal ECG and low voltage injuries do 199543 admitted to the emergency department not require cardiac monitoring. Authors also suggested with household electrical injuries that ECG is not indicated for children with low-voltage injuries, no loss of consciousness, no tetany, no water contact, and no current crossing the heart region Bailey et al, Prospective evaluation of a set of admission II Guidelines for admission were used in the majority of 20001 guidelines after electrical injury. cases. According to the guidelines, all patients with Guidelines were applied to a total of 224 high-voltage injuries were admitted, as were patients patients with low-voltage injuries with ECG abnormalities, past cardiac history, water contact, and tetany Chandra et al, Prospective evaluation of 34 patients II Time course of CK-MB elevation in patients with 19906 admitted with high-voltage electrical electrical injuries suggests that it is cardiac in etiology. injuries to determine predictors of ECG may not be reliable for diagnosing myocardial myocardial damage damage Cunningham, Retrospective study of 70 patients admitted II Discharged all patients with low-voltage injuries who are 199144 with electrical injury asymptomatic and had normal ECG without complication Guinard et al, Prospective evaluation of 10 patients III Demonstrated poor reliability of CK-MB to identify 198715 admitted with electrical injuries cardiac injuries Housinger et al, Prospective study of 16 patients to determine III Demonstrated poor correlation between elevation of 19857 incidence of possible myocardial damage CK-MB levels and ECG abnormalities. Pyrophosphate following electrical burn scans were used as diagnostic standard for cardiac injury Hunt et al, Retrospective review of 102 patients with II All cardiac abnormalities were evident either on 19809 high-voltage injuries admission of within several hours of hospitalization Jensen et al, Three case reports of late presentation of III Three patients with late presentation of cardiac 198711 cardiac abnormalities after electrical injury abnormalities. However, none of the patients were evaluated immediately after injury Lewin et al, Case report of 19-year old patient with III Demonstrated correlation of CK-MB levels with ECG 19834 myocardial injury after electrical injury abnormalities and myocardial injury Purdue and Hunt, Retrospective study of 48 patients admitted II Designed a protocol for determining which patients 19865 with high-voltage injuries. On the basis of should be admitted following high voltage injury. No these findings, a prospective study of 10 complications following discharge of patients with high patients applying guidelines for admission voltage injuries and no other indications for admission.Comment: First study to demonstrate safety of discharging patients with high-voltage injuries and normal ECGs. However, small group of patients studied Wallace et al, Retrospective study of 35 pediatric patients II Children with low-voltage injuries and normal ECGs can 19958 with both low and high voltage injuries be discharged. However, all patients with high-voltage injuries were admitted and monitored Zubair et al, Retrospective study of 127 pediatric patients II Recommend 4 hours of monitoring for all patients before 199712 with low- and high-voltage injuries discharge and admission of all patients with high- voltage injuries, loss of consciousness, or ECG abnormalities
  • 5. Journal of Burn Care & Research Volume 27, Number 4 Arnoldo et al 443 compromise, increased compartment pressure, “compartment pressure,” “Doppler flow meter,” and systemic clinical deterioration from sus- “technetium 99m pyrophosphate,” “infrared pho- pected ongoing myonecrosis. Decompression toplethysmography,” and “burn injury” was per- includes forearm fasciotomy and assessment of formed, and relevant articles were reviewed. Stud- muscle compartments. The decision to include ies of patients with lower-extremity injuries were a carpal tunnel release should be made on a included because of the scarcity of data involving ex- case-by-case basis. clusively the upper extremity. An attempt was made Options. There are several methods to evaluate the however to analyze the data involving the upper ex- injured extremity. Compartment pressures may be tremity exclusively where possible. measured as an adjunct to clinical examination. Pres- sures greater than 30 mm Hg, or tissue pressure Scientific Foundation reaching within 10 to 20 mm Hg of diastolic pres- Electrical injuries, including lightning strikes, should sure, may be used as evidence of increased compart- be referred to a specialized burn center as per Amer- ment pressure and potential deep-tissue injury, indi- ican Burn Association criteria.18 Many surgeons ad- cating the need for surgical decompression in the vocate immediate surgical exploration (usually within appropriate clinical setting. Technetium-99m pyro- the first 24 hours), and decompression of patients phosphate scan may be used as an adjunct to clinical with high-voltage electrical injuries.19,20 –32 Early ex- examination at centers experienced with this technol- ploration, fasciotomy, and debridment are followed ´ ogy. Doppler flow meter can be used as an adjunct to by serial debridment of necrotic tissue and subse- ´ assess extremity perfusion. It should not be relied on quent closure. These studies are somewhat difficult to as the sole indicator of deep-tissue viability and ade- interpret; however, because of the differences in the quate perfusion. degree of injury no prospective, randomized, con- trolled trials evaluating immediate exploration have been performed. The rational for this aggressive ap- OVERVIEW proach relates to thermal mechanics. Joule’s law de- Purpose fining the amount of power (heat) delivered to an object: The purpose of this guideline is to review the princi- Power (J-Joule) I2 (Current) times R (Resistance). ples of monitoring and treatment of high-voltage Accordingly, deep muscle necrosis can occur in the electrical burn injury to the upper extremity. The up- muscle adjacent to bone, which has a high resis- per extremity is commonly injured after high-voltage tance.33–35 Failure to perform adequate fasciotomy electrical and carries with it a high rate of morbidity. and to evaluate all muscle compartments may lead to misdiagnosis of deep thermal injury.20 This approach Clinical Problem however, commits the patient to several operations Burns resulting from high-voltage electric current and may prolong hospital stay and morbidity. ( 1000 V) often are associated with a greater degree In the d’Amato20 series, six patients underwent of deep-tissue injury than is initially appreciated. As a emergency exploratory surgery and amputation for result these rather infrequent injuries, which make up obvious necrotic extremities, followed by serial de- ´ only 3% to 12% of burn center admissions,16 are as- bridment. No patient required an amputation for sociated with high amputation rates and greater use misdiagnosed deep muscle necrosis. However, of resources than comparable %TBSA cutaneous missed injury was present in two patients, who re- burns.6,10,17 Unnecessary exploration can increase quired further surgical intervention, although neither morbidity, length of stay, and the use of scarce re- required amputation because of the missed injury. sources. Delayed exploration and decompression in Parshley’s series evaluated 41 patients with 27 ex- the compromised extremity, however, may result in tremities explored. Amputation rate was 40% with 10 increased amputation rates along with increased or- extremities salvaged, which the authors attribute to gan failure and mortality.31 early aggressive operative intervention. Haberal’s se- ries of 94 patients had an amputation rate of 43%. The Process authors attributed this high amputation rate in part A Medline search from 1966 to the present was used because of a delay in surgical exploration as a result of to evaluate monitoring and the need for early explo- patients being transferred from nonspecialized facili- ration and fasciotomy in electrical injury to the ex- ties. Achauer et al21 reported a series of 22 patients tremity. A search for the key words, “electrical in- with an amputation rate of 40%. They recommend jury,” “fasciotomy,” “compartment syndrome,” “extensive debridement of all damaged tissue and ex-
  • 6. Journal of Burn Care & Research 444 Arnoldo et al July/August 2006 Table 2. Evidentiary table: high-voltage electric injury to upper extremity Reference Description Data Class Comments Quinby et al, Retrospective review of 44 patients II In conductive burns with entrance site in hand, incision was 197825 divided into 22 with electric arc and carried from hand to interconnect the arc burns at wrist, 22 with flow of current elbow, and shoulder. Fasciotomies done if muscle discolored, or tense, transverse carpal ligament release done. Amputation rate 68% Luce et al, Retrospective review of 31 patients II Fasciotomy and wound exploration and debridement within 198426 24 hours of admission Amputation rate 35.5% Parshley et al, Retrospective review 41 patients with II Early fasciotomy in patients with passage of current 198522 passage of current Amputation rate 40% Achauer et al, Retrospective analysis of electric injury II Extensive debridement and compartment release almost always 199421 of the hand in 22 patients done on day of injury. Amputation rate 40% Mann et al, Retrospective review 62 patients with II Fasciotomy indications: severe pain and loss of arterial 199631 high voltage upper extremity injury Doppler signal, neurologic deterioration, systemic clinical deterioration from suspected ongoing myonecrosis. Carpal tunnel release performed along with fasciotomy. 16 of 62 patients (25.8%) required emergent decompression within first 24 hours. Amputation rate in these patients 45%. Overall amputation rate 10% Yowler et al, Retrospective chart review 51 patients III Indications for fasciotomy: Elevated muscle compartment 199832 with high voltage injuries to the pressure greater than 30 mmHg. Neurologic dysfunction, upper and lower extremity vascular compromise, extensive deep burn. 11 patients under went 18 major amputations DiVincenti et al, Retrospective review of 65 electrical III Early fasciotomy indicated for cyanosis of distal uninjured skin, 196924 injuries over 17 years, upper and impaired capillary refill, progressive neurologic change, lower extremities included, high and brawny edema and muscle compartment tightness. low voltage injuries included Amputation rate 32.5% Butler et al, Retrospective review of 182 cases over III 40 patients underwent an average of 5 operations. Marked 197723 twenty years. Includes high voltage swelling of the wrist and hand, the volar carpal ligament is and low voltage injuries divided at time of extremity fasciotomy. Amputation rate 65% Mann et al, Series of 8 patients with high voltage III Early decompression fasciotomy and debridement. 197527 injury. Includes upper and lower Amputations done on at least one extremity in all patients extremities D’Amato et al, Series of 6 patients with high voltage III Mandatory exploration of forearm and hand compartments 199420 upper extremity injury following initial resuscitation. All patients required amputation Hussmann et al, Retrospective evaluation of 38 high III Early serial debridement of obviously necrotic tissue, 199545 voltage injuries. Included upper and fasciotomy including carpal tunnel release for “compartment lower extremity syndrome” 39 amputations performed in 38 patients Saffle et al, Evaluation of wick catheter to measure II Recommended routine measurement of IMP as a more 198035 intramuscular compartment sensitive than Doppler pulses, and use of a threshold value pressures (IMP) in 31 extremities in of 30 mmHg for performance of escharotomy 18 patients, compared with clinical and Doppler findings Moylan et al, Prospective evaluation of ultrasonic II Escharotomy is indicated when Doppler flow is absent in distal 197136 flowmeter to assess circulatory arteries or arches. Note: This paper documents that Doppler changes in 60 limbs in 24 patients pulses can be present in the face of clinical evidence of tissue with circumferential burns compression and ischemia Salisbury et al, Evaluated post-mortem intrinsic II/III Muscle ischemia or necrosis can occur with intact pulses and even 197437 muscle biopsies following extremity following escharotomy. Note: since this was a post-mortem burns. Presence of necrosis was study, tissue necrosis may have been a non specific finding similar in patients with (72.2%) and without (66%) escharotomies (Continued)
  • 7. Journal of Burn Care & Research Volume 27, Number 4 Arnoldo et al 445 Table 2. (Continued) Reference Description Data Class Comments Smith et al, Prospective evaluation of infrared III Advocated use of PPG as a noninvasive method of assessing 198438 photoplethysmography (PPG) to vascular compromise. This study supports an IMP 30 mm evaluate vascular status in burned Hg as an appropriate threshold for escharotomy in burned extremities and compared with IMP, extremities Doppler, and muscle blood flow (MBF). PPG correlated well with IMP and MBF, but poorly with Doppler with changes noted with IMP 30 mm Hg Chen et al, High resolution color and pulse III Different tissue found to have differing degree of injury. 200339 Doppler ultrasonography used to Concluded that ultrasound could demonstrate morphologic determine burn wound area in 12 changes in subcutaneous tissue, muscle, and blood vessels patients with deep electrical injury after deep electric injury Hunt et al, Technetium-99 m pyrophosphate scans II Location and extent of muscle injury was correctly ascertained 197940 performed in 14 patients with high preoperatively in all patients voltage electrical injury. Scans were performed between first and fifth day post injury Affleck et al, Retrospective review of computerized III Revealed a sensitivity of 94% and specificity of 100% showing 200141 registry identified 11 patients who demarcation between viable and nonviable tissue, confirmed underwent Pyrophosphate (PyP) at operation scan. Eight patients had high voltage electrical injury, one had frostbite, and two had soft-tissue infection Hammond et al, Early scanning (within 3 days of injury) II Compared to control group of 17 patients treated without 199442 with PyP in 19 limbs in 15 patients PyP scan, the scan was not associated with reduced length with electrical injury. Sensitivity of of stay, or with decreased number of surgical procedures 75% and specificity of 100% tensive compartment release done as an emergency putation was ultimately required in 10% of the ex- (almost always on the day of injury).” Luce reported tremities. Extremities that were not decompressed a series of 31 patients with an extremity amputation immediately did not require amputation. The ampu- rate of 35.5% who “were taken to the operating room tation rate for those patients requiring immediate sur- within 24 hours of admission.” In the DiVincenti et gical decompression was 45%. This amputation rate is al24 series of 65 patients, there was an amputation rate similar to previous studies, which appear to include of 32.5%. There are no studies that specifically eval- patients with lesser degree of injury. In the series from uated the impact of timing on treatment outcome. the Army Institute of Surgical research,32 51 patients Some recent literature has supported a more selec- with high-voltage injury were managed selectively. tive approach to management may reduce the num- Indications for operative intervention were evidence ber of operative interventions and subsequently the of neurologic dysfunction, vascular compromise, ex- morbidity of high voltage electrical injury.31,32 Mann tensive deep burn, or increased muscle compartment et al31 followed a selective management algorithm for pressures (repeated measurements 30 mm Hg). A upper-extremity high-voltage electrical injury. Indi- total of 11 patients (21.6%) underwent 18 major ex- cations for surgical decompression included extrem- tremity amputations. ities that exhibited progressive peripheral nerve dys- No precedent exists in the literature for measuring function, clinical manifestations of compartment compartment pressures in the setting of high-voltage syndrome, or injury sufficient to cause difficulty in upper-extremity electrical injury. Some surgeons ad- resuscitating the patient. Sixty-two patients had a to- vocate their use, however, on the basis of the ortho- tal of 100 upper-extremity injuries. Early (within 24 pedic and vascular literature.33,34 Measurement of hours of admission), surgical decompression was re- compartment pressures in circumferential extremity quired in 22% of injured upper extremities. An am- burn wounds has been recommended by Saffle et al.35
  • 8. Journal of Burn Care & Research 446 Arnoldo et al July/August 2006 A wick-catheter technique was used to measure intra- resolution ultrasound, may add much-needed clarity muscular pressures. A threshold of 30 mm Hg was an to this clinical problem. indication for escharotomy (based on vascular com- Surgical Management. Prospective randomized partment syndrome literature). Whether or not this studies that evaluate immediate vs expectant debrid- ´ can be extrapolated to include electric injury is un- ment using well-defined criteria would be useful in clear. In addition, Moylan et al36 showed that ultra- defining guidelines for surgical management of the sonic (Doppler flow meter) signal from the distal ar- injured extremity. teries and palmar arch was a more sensitive indicator Evidentiary Table. Table 2 summarizes research of perfusion than clinical palpation. 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