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Curare and Related Compounds George Hsiao 2008
Therapeutic uses of anti-ChE agents   (1)  Paralytic Ileus and Atony of the Urinary Bladder : Neostigmine is used for the relief of abdominal distension and acute colonic pseudoobstruction from a variety of medical and surgical causes. (2)     Glaucoma and Other Ophthalmologic Indication (3)     Myasthenia Gravis (4)   Prophylaxis in Cholinesterase Inhibitor Poisoning  (nerve gas: pyridostigmine) (5)   Intoxication by Anticholinergic Drugs  (atropine: CNS effects: physostigmine) (6)     Alzheimer’s Disease  (tacrine, donepezil)
 
Myasthenia Gravis vs Normal Condition
 
 
Neurofibrillary Tangles and Senile Plaques
Cholinergic Innervation
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Terrorism !!!

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Nmj Nov08[2]

  • 1. Curare and Related Compounds George Hsiao 2008
  • 2. Therapeutic uses of anti-ChE agents (1) Paralytic Ileus and Atony of the Urinary Bladder : Neostigmine is used for the relief of abdominal distension and acute colonic pseudoobstruction from a variety of medical and surgical causes. (2)     Glaucoma and Other Ophthalmologic Indication (3)     Myasthenia Gravis (4)   Prophylaxis in Cholinesterase Inhibitor Poisoning (nerve gas: pyridostigmine) (5) Intoxication by Anticholinergic Drugs (atropine: CNS effects: physostigmine) (6)     Alzheimer’s Disease (tacrine, donepezil)
  • 3.  
  • 4. Myasthenia Gravis vs Normal Condition
  • 5.  
  • 6.  
  • 9.