2. Therapeutic uses of anti-ChE agents (1) Paralytic Ileus and Atony of the Urinary Bladder : Neostigmine is used for the relief of abdominal distension and acute colonic pseudoobstruction from a variety of medical and surgical causes. (2) Glaucoma and Other Ophthalmologic Indication (3) Myasthenia Gravis (4) Prophylaxis in Cholinesterase Inhibitor Poisoning (nerve gas: pyridostigmine) (5) Intoxication by Anticholinergic Drugs (atropine: CNS effects: physostigmine) (6) Alzheimer’s Disease (tacrine, donepezil)