Valentines day-card-2011

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Anthony Salvagno

This is a valentine's day card I designed.

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Scientific information is published in peer reviewed journals as a complete account. Unfortunately there is nothing complete about the process. Frequently intermediate and supplementary experimental data is excluded, methods are not nearly detailed enough, and results are manipulated for appearance. Open notebook science aims to be a complete account of the scientific process: from ideas and planning, to experimental setup and protocol design, all the way through data interpretation and commentary. Here I talk about tools to create and support an open notebook, effective use of the medium, and how social interaction creates a community using examples from my own open notebook for research.

Open Notebook Science - UNM Biomed Symposium Edition

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Deuterium is present in all naturally occurring water, and accounts for 1 in 6420 hydrogen atoms. Seemingly insignificant, that ratio is actually quite impactful in life sciences. Pure deuterium oxide (heavy water) has been found to be toxic to eucharyotic organsims, and has been found to be inhibitory in smaller doses. Here I present results that demonstrate that in even smaller doses the concentration of deuterium has a dramatic effect on life processes. I also show that at the molecular level, deuterium has a stabilizing effect. By simply changing the properties of the solvent, there can be dramatic effects that impact a variety of experiments. For the entire story, please refer to my dissertation: https://docs.google.com/document/d/1p9-qqF8oUcwNGJjZG3CoKL2xvIhbqKCFQ7_faegNPIU/edit?usp=sharing

The Biophysical Effects of Heavy Water

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Presented on 2/15/13 for Student Research Day at UNM. Scientific information is published in peer reviewed journals as a complete account. Unfortunately there is nothing complete about the process. Frequently intermediate and supplementary experimental data is excluded, methods are not nearly detailed enough, and results are manipulated for appearance. Open notebook science aims to be a complete account of the scientific process: from ideas and planning, to experimental setup and protocol design, all the way through data interpretation and commentary. Here I talk about tools to create and support an open notebook, effective use of the medium, and how social interaction creates a community using examples from my own open notebook for research.

Open Notebook Science: Research in Real-Time

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In 1988, molecular gastronomy was born. The field is aimed to investigate the scientific processes of cooking by: (1) the social phenomena linked to culinary activity, (2) the artistic component of culinary activity, and (3) the technical component of culinary activity. This talk was hosted at Explora! on 11/20/15 for their Science of Food event. This presentation and demonstration was funded through Girl Scouts of New Mexico Trails

The Modern Cuisine Movement: The Intersection of Science and Culinary Arts

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La gestion quotidienne d’une présence web demande un plan de gouvernance clair et efficace, des politiques précises et des mécaniques de production et de gestion de contenu. Mais comment implanter ces éléments dans une vaste organisation aux paliers multiples? Dans le même ordre d’idée, comment gérer une crise 2.0 de façon efficace dans une telle organisation? Comment définir et implanter un plan de gouvernance web? Comment bien se préparer à une crise 2.0? Comment produire, gérer et diffuser son contenu de façon optimale? Guillaume Brunet aura l’occasion, lors de cette conférence, de souligner les meilleures pratiques en matière de communications web, de gouvernance et de gestion de crise dans les institutions et organismes publics.

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“Open source” is the act of providing software, technology, or process for free and inviting amendments and derivation. Open sourcing philosophy has emerged primarily in the software industry, but over the past decade the open movement has risen from an unconventional concept to an emerging approach now applied to many other fields including communication, STEM, art, and many others. When money is involved, open policies are seen as unfavorable and have been largely disregarded. Current resistance to open access is not well understood but may be stem from questions of profitability or fears of losing intellectual property. In this open discussion, which we want the audience to participate in, we hope to present the possibility of using open practices to build a successful business model. What if providing open access could make a company more profitable? What if transparency brought more customers? What’s more, what if open practices could add a new dimension to corporate social responsibility? We present the idea that openness in a corporation would actually be extremely beneficial to businesses and organizations alike, and could drive profitability and induce trust while minimizing corruption and ensuring corporate, societal, and fiscal responsibility.

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This is the presentation based on our propsal of the same name. The presenters were Laura Pawlikowski, John Montoya, Ken Seal, and myself. We discuss functionalizing an AFM tip with antibodies for protein detection and discuss several possible uses for such a device. Conceptually, proteins bound to DNA can be flowed down a nanochannel and can be detected by an AFM tip in the channel. The detection will be based on the interaction between antibodies and their antigens (the proteins).

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This is a presentation I gave for my Candidacy for PhD. I present on the possibilities of probing protein-DNA interactions using Optical Tweezers. I discuss simulating force curves from optical tweezers, background information, and the molecular biological preparations involved. Finally I conclude with future applications of the technique that range from analysis of alternative splicing, transcriptional studies, and telomere mapping.

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