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Respons imun pada Bayi dan
Anak terhadap Virus
Prof DR Dr Ariyanto Harsono SpA(K)
Virus

IL-12/ IL-1
IL-6
TCR

CTL

IL-4

MHC-II

Th0

MHC-I

IL-1

Th-2

B-Cell

IL-2, IFN-γ

TNF-β, IFN-γ

IL-10

Sel Abnormal
FASL

IL-5

I L-2
IFN-γ

Th.1

SEL MEMORI

SEL PLASMA

L

SEL-NK
SEL-NK AKTIF

Memory Cells

FC-R

SITOTOKSIN

ADCC

SEL-LISIS

SEL ABNORMAL

Prof DR Dr Ariyanto Harsono
SpA(K)

2
Prof DR Dr Ariyanto Harsono
SpA(K)

3
Prof DR.dr. Ariyanto Harsono SpAK
Prof DR Dr Ariyanto Harsono
SpA(K)

4
Prof DR.dr. Ariyanto Harsono SpAK
Prof DR Dr Ariyanto Harsono
SpA(K)

5
Th1

Prof DR Dr Ariyanto Harsono
SpA(K)

(J Allergy Clin Immunol 1999;118:124-6)
6
Prof DR Dr Ariyanto Harsono
SpA(K)

7
virus

virus
Prof DR Dr Ariyanto Harsono
SpA(K)

8
Prof DR Dr Ariyanto Harsono
SpA(K)

9
Prof DR Dr Ariyanto Harsono
SpA(K)

10
Prof DR Dr Ariyanto Harsono
SpA(K)

11
INNATE Immunity,,,,,

Prof DR Dr Ariyanto Harsono
SpA(K)

12
Prof DR Dr Ariyanto Harsono
SpA(K)

13
Prof DR Dr Ariyanto Harsono
SpA(K)

14
Effectors mechanisms against extracellular
pathogens
OPSONISATION
Virus in extracellular space

+
Ab

OPSONISATION

Fc
receptor
binding
Prof DR Dr Ariyanto Harsono SpA(K)

Phagocytosis
15
Effectors mechanisms against extracellular
pathogens
COMPLEMENT Activation
Virus in extracellular space

Lysis

+
Ab &
COMPLEMENT

Opsonisation

Complement &
Fc receptor binding
Prof DR Dr Ariyanto Harsono SpA(K)

Phagocytosis
16
Prof DR Dr Ariyanto Harsono
SpA(K)

17
Prof DR Dr Ariyanto Harsono
SpA(K)

18
Prof DR Dr Ariyanto Harsono
SpA(K)

19
Prof DR Dr Ariyanto Harsono SpA(K)

20
Gejala Klinik
Mononucleosis (Glandular Fever)

Prof DR Dr Ariyanto Harsono
SpA(K)

21
Prof DR Dr Ariyanto Harsono
SpA(K)

22
Cytomegalovirus Infection
Congenital Cytomegalovirus
Infection

Prof DR Dr Ariyanto Harsono
SpA(K)

23
Prof DR Dr Ariyanto Harsono
SpA(K)

24
Wart

Prof DR Dr Ariyanto Harsono
SpA(K)

25
Moluscum Contagiosum

Prof DR Dr Ariyanto Harsono
SpA(K)

26
Herpes Simplex

Prof DR Dr Ariyanto Harsono
SpA(K)

27
Condyloma acuminata

Prof DR Dr Ariyanto Harsono
SpA(K)

28
Conjunctivitis

Prof DR Dr Ariyanto Harsono
SpA(K)

29
Mumps

Prof DR Dr Ariyanto Harsono
SpA(K)

30
Common cold

Prof DR Dr Ariyanto Harsono
SpA(K)

31
Acrodermatitis enteropathica

Prof DR Dr Ariyanto Harsono
SpA(K)

32
Herpes Zoster

Prof DR Dr Ariyanto Harsono
SpA(K)

33
Fifth disease (Erythema infectiosum)

Prof DR Dr Ariyanto Harsono
SpA(K)

34
Measles

Prof DR Dr Ariyanto Harsono
SpA(K)

35
Rubella

Prof DR Dr Ariyanto Harsono
SpA(K)

36
Roseola Infantum

Prof DR Dr Ariyanto Harsono
SpA(K)

37
Scarlet Fever

Prof DR Dr Ariyanto Harsono
SpA(K)

38
varicella

Prof DR Dr Ariyanto Harsono
SpA(K)

39
Variola

Prof DR Dr Ariyanto Harsono
SpA(K)

40
Avian Flu
Siklus Avian flu

Virus h5n1

Prof DR Dr Ariyanto Harsono
SpA(K)

41
Swain Flu
Siklus Swain flu

Virus A/H1 N1

Prof DR Dr Ariyanto Harsono
SpA(K)

42
Singapore Flu

Prof DR Dr Ariyanto Harsono
SpA(K)

43
Hongkong flu

Prof DR Dr Ariyanto Harsono
SpA(K)

44
Prof DR Dr Ariyanto Harsono
SpA(K)

45
SARS

Prof DR Dr Ariyanto Harsono
SpA(K)

46
Prof DR Dr Ariyanto Harsono
SpA(K)

47
HIV/AIDS

Prof DR Dr Ariyanto Harsono
SpA(K)

48
Prof DR Dr Ariyanto Harsono SpA(K)

49
Prof DR Dr Ariyanto Harsono
SpA(K)

50
Prof DR Dr Ariyanto Harsono SpA(K)

51
Terimakasih
52

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