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May 2020
Preterm
27%
Sepsis &
pneumonia
26%
Asphyxia
23%
Congenital
7%
Tetanus
7%
Diarrhoea
3%
Others
7%
4 million neonatal deaths: When? Where? Why? Lancet 2005; 365: 891–
900
WHY TO LEARN NEWBORN RESUSCITATION ?
 Birth asphyxia ~25% neonatal mortality
 ~90% requiring little or no assistance
 10% of newborns need some assistance
 Only 1% require extensive resuscitation
 Always be prepared to resuscitate, even those
with no risk factors will require resuscitation.
Assess baby’s risk for requiring resuscitation
Provide warmth
Position, clear airway if required
Dry, stimulate to breathe
Give supplemental oxygen, as
required
Assist ventilation with
positive pressure
Intubate the trachea
Provide chest
compressions
Medications
Always
needed
Needed less
frequently
Rarely needed
BEFORE BIRTH
 Oxygen supply by placental
membranes
 No role of lungs. Fluid filled
alveoli and constricted
arterioles due to low Po2 in
fetal blood.
AFTER BIRTH
 Baby cries  takes first breath  air enters
alveoli  alveolar fluid gets absorbed 
increased Po2  relaxes pulmonary arterioles 
decreased PVR
 Umbilical arteries constrict +
clamp cord  closure of
Umbilical Arteries and
Umbilical Vein  increased
SVR
 Decreased PVR + Increased SVR
 functional closure of
Ductus Arteriosus  increased
blood flow into lungs 
oxygenation  supply to body
through aorta.
 Low muscle tone
 Respiratory depression
(apnoea / gasping)
 Tachypnea
 Bradycardia
 Hypotension
 Cyanosis
 Provide warmth : Radiant warmer,
don’t cover with towels.
 Position head and clear airway as
necessary
 Dry and stimulate the baby to
breathe, reposition
 Suction mouth first, then
nose
 “M” before “N”
 To prevent aspiration of
mouth contents
Stimulate :
Flicking the
soles/ drying &
rubbing the back
Evaluation
 Ventilation of the lungs is the
single most and most effective
step in newborn resuscitation
Indications:
 Gasping/apnea
 HR < 100/min
 SpO2 remains below target values
despite free flow supplemental
oxygen increased to 100%.
Appropriate Sizes
 Mask should
Rest on Chin
Cover Mouth
& Nose
 Gently pull infant’s jaw forward to mask
 Use a “C-grip” to hold mask to infant’s face,
using the 3rd finger to hold jaw up to mask
40 to 60 breaths per minute
Start With 21% ( higher in preterm's) oxygen
and increase according to target Saturation
Initial Pressure at 20mmH2O
 Most Important sign is the rising of HR
 Improvement in Oxygen Saturation
 Equal and adequate breath sounds B/L
 Good Chest rise
If heart rate <100 bpm
despite adequate
ventilation for 30
seconds,
Corrective steps Action
M Mask Adjustment Ensure Good seal of
mask on face
R Reposition airway Sniffing Position
S Suction Mouth and nose If secretions present
O Open mouth Ventilate with baby
mouth slightly open and
lift the jaw forward
P Pressure increase Gradually increase the
pressure every few
breaths
A Airway alternative Consider ET or Laryngeal
mask airway
If heart rate <60 bpm
despite adequate
ventilation for 30
seconds,
Indications :
 HR <60/min
despite at least 30
sec of effective
PPV
Strongly consider Endotracheal intubation at this point
as it ensures adequate ventilation and facilitates the
coordination of ventilation and chest compressions
Rationale:
 HR<60/min despite PPV indicates
very low O2 levels and significant acidosis 
depressed myocardium  no blood in lungs
to get oxygenated(supplied by PPV)
 Chest compressions + effective ventilation
(ET/PPV)  oxygenation of blood 
recovery of myocardium to function
spontaneously  HR increases  O2 supply
to brain increases
Technique:
 Thumb technique: 2 thumbs
depress the sternum, hands
encircle the torso and the
fingers support the spine.
Preferred technique
 2 – Finger technique: Tips of
middle & index/ring finger of
one hand compresses
sternum, other hand supports
the back.
 Thumb technique is
preferred as
 Better control of depth of
compression
 Can provide pressure
consistently
 Superior in generating peak
systolic and coronary arterial
perfusion pressure.
For small chests with
thumbs overlapped
2- finger
 Depth : 1/3rd of the
anteroposterior
diameter of chest.
 Duration of
downward stroke
should be shorter
than the duration of
release
 Do not lift the
fingers off the chest
Coordination of chest compressions and
ventilation:
 Avoid giving compression and ventilation simultaneously
 1 breathe after every 3 compressions
 Ratio is 1 : 3 or 30: 90 per minute
 One cycle: 2 sec, 3Compresssions + 1 ventilation
 1 minute : 30 cycles or 120 events (90 compressions + 30
breaths)
When to stop chest compressions?
 Reassess after 45-60 sec, if HR > 60/min stop
chest compressions and increase breaths to
40-60 per minute.
If HR is not improving…
 Insert an umbilical catheter and give IV
epinephrine
 WHEN TO CONSIDER INTUBATION ?
Indications in resuscitation
 Baby is floppy, not crying, and preterm
 HR < 100/min, gasping/apnea
 HR < 100/min inspite of PPV
 HR < 60/min
 No adequate chest rise and no clinical
improvement
 If chest compressions are needed, intubation
provides better coordination and efficacy of PPV
 To administer drugs
 Special conditions
 Extreme Prematurity
 Surfactant administration
 Suspected diaphragmatic hernia
Mechanism of action :
 Increases systemic vascular resistance
 Increases coronary artery perfusion pressure
 Improves blood flow to myocardium and
restores depleted ATP
Indications :
 If HR remains < 60/min even after 30 sec of
effective ventilation preferably after
intubation and at least another 45-60 sec of
coordinated chest compressions and
effective ventilation
Administration :
 Intravenous (recommended)
 Endotracheal
Preparation and dosage:
 Adrenaline vial 1ml = 1mg (1:1000 solution)
 Dilute with NS to make 1:10,000 solution
(1ml = 100 mcg)
 IV : 0.1-0.3 ml/kg = 10-30 mcg/kg
 ET : 0.5 – 1 ml/kg = 50-100 mcg/kg
 Give rapidly – as quickly as possible
 Can repeat every 3-5 minutes
Indications:
 Bradycardia not improving with adrenaline
Volume Expanders:
 Normal saline (recommended)
 Ringer lactate
 Dosage: 10 ml/kg
 Route : Umbilical vein
 Rate: over 5-10 min , rapid infusion may
cause IVH in <30 weeks babies
 Additional resources , additional personnel,
additional thermoregulation strategy
 Portable warming pad
 Polyethylene Plastic wrap (< 29wk)
 Prewarmed transport incubator
 Use of Oxymeter, blender to target Spo2 85%- 95%
 Use Lower PIP 20-25 cm of H2O during PPV
 Consider giving CPAP
 Consider Surfactant
 Avoid hyperthermia, consider therapeutic
hypothermia within 6 hrs for >36wks and
Acute perinatal HIE
 Monitor for Apnea, bradycardia, BP, SPo2
&Urine output.
 Monitor B. Sugars, electrolytes, Hematocrit ,
Platelets, ABG
 Maintain adequate oxygenation & support
ventilation as needed
 Delay feeds, Start IV fluids, consider
parenteral nutrition
 Consider inotropes,fluid bolus
 Ensure adequate ventilation before giving
sodium bicarbonate(only in severe metabolic
acidosis)
 Choanal atresia – oral Airway
 Pierre Robin : place prone , 12F Et through
nose with tip in post pharynx
 Laryngeal web, cystic hygroma, Cong.
Goiter- ET/tracheostomy
 Pneumothorax : Percutaneous needle
aspiration
 Pleural effusion : Percutaneous needle
aspiration
 Congenital Diaphragmatic hernia
 Can we differ resuscitation?
 Can we to stop resuscitation?
THANK YOU

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Newborn Resuscitation C2 2020.pptx

  • 3. WHY TO LEARN NEWBORN RESUSCITATION ?  Birth asphyxia ~25% neonatal mortality  ~90% requiring little or no assistance  10% of newborns need some assistance  Only 1% require extensive resuscitation  Always be prepared to resuscitate, even those with no risk factors will require resuscitation.
  • 4. Assess baby’s risk for requiring resuscitation Provide warmth Position, clear airway if required Dry, stimulate to breathe Give supplemental oxygen, as required Assist ventilation with positive pressure Intubate the trachea Provide chest compressions Medications Always needed Needed less frequently Rarely needed
  • 5.
  • 6. BEFORE BIRTH  Oxygen supply by placental membranes  No role of lungs. Fluid filled alveoli and constricted arterioles due to low Po2 in fetal blood.
  • 7. AFTER BIRTH  Baby cries  takes first breath  air enters alveoli  alveolar fluid gets absorbed  increased Po2  relaxes pulmonary arterioles  decreased PVR
  • 8.  Umbilical arteries constrict + clamp cord  closure of Umbilical Arteries and Umbilical Vein  increased SVR  Decreased PVR + Increased SVR  functional closure of Ductus Arteriosus  increased blood flow into lungs  oxygenation  supply to body through aorta.
  • 9.  Low muscle tone  Respiratory depression (apnoea / gasping)  Tachypnea  Bradycardia  Hypotension  Cyanosis
  • 10.
  • 11.
  • 12.  Provide warmth : Radiant warmer, don’t cover with towels.  Position head and clear airway as necessary  Dry and stimulate the baby to breathe, reposition
  • 13.  Suction mouth first, then nose  “M” before “N”  To prevent aspiration of mouth contents
  • 14. Stimulate : Flicking the soles/ drying & rubbing the back Evaluation
  • 15.  Ventilation of the lungs is the single most and most effective step in newborn resuscitation Indications:  Gasping/apnea  HR < 100/min  SpO2 remains below target values despite free flow supplemental oxygen increased to 100%.
  • 16. Appropriate Sizes  Mask should Rest on Chin Cover Mouth & Nose
  • 17.  Gently pull infant’s jaw forward to mask  Use a “C-grip” to hold mask to infant’s face, using the 3rd finger to hold jaw up to mask
  • 18. 40 to 60 breaths per minute Start With 21% ( higher in preterm's) oxygen and increase according to target Saturation Initial Pressure at 20mmH2O
  • 19.  Most Important sign is the rising of HR  Improvement in Oxygen Saturation  Equal and adequate breath sounds B/L  Good Chest rise
  • 20. If heart rate <100 bpm despite adequate ventilation for 30 seconds,
  • 21. Corrective steps Action M Mask Adjustment Ensure Good seal of mask on face R Reposition airway Sniffing Position S Suction Mouth and nose If secretions present O Open mouth Ventilate with baby mouth slightly open and lift the jaw forward P Pressure increase Gradually increase the pressure every few breaths A Airway alternative Consider ET or Laryngeal mask airway
  • 22. If heart rate <60 bpm despite adequate ventilation for 30 seconds,
  • 23. Indications :  HR <60/min despite at least 30 sec of effective PPV Strongly consider Endotracheal intubation at this point as it ensures adequate ventilation and facilitates the coordination of ventilation and chest compressions
  • 24. Rationale:  HR<60/min despite PPV indicates very low O2 levels and significant acidosis  depressed myocardium  no blood in lungs to get oxygenated(supplied by PPV)  Chest compressions + effective ventilation (ET/PPV)  oxygenation of blood  recovery of myocardium to function spontaneously  HR increases  O2 supply to brain increases
  • 25. Technique:  Thumb technique: 2 thumbs depress the sternum, hands encircle the torso and the fingers support the spine. Preferred technique  2 – Finger technique: Tips of middle & index/ring finger of one hand compresses sternum, other hand supports the back.
  • 26.  Thumb technique is preferred as  Better control of depth of compression  Can provide pressure consistently  Superior in generating peak systolic and coronary arterial perfusion pressure.
  • 27. For small chests with thumbs overlapped
  • 28.
  • 30.  Depth : 1/3rd of the anteroposterior diameter of chest.  Duration of downward stroke should be shorter than the duration of release  Do not lift the fingers off the chest
  • 31. Coordination of chest compressions and ventilation:  Avoid giving compression and ventilation simultaneously  1 breathe after every 3 compressions  Ratio is 1 : 3 or 30: 90 per minute  One cycle: 2 sec, 3Compresssions + 1 ventilation  1 minute : 30 cycles or 120 events (90 compressions + 30 breaths)
  • 32. When to stop chest compressions?  Reassess after 45-60 sec, if HR > 60/min stop chest compressions and increase breaths to 40-60 per minute. If HR is not improving…  Insert an umbilical catheter and give IV epinephrine
  • 33.  WHEN TO CONSIDER INTUBATION ? Indications in resuscitation  Baby is floppy, not crying, and preterm  HR < 100/min, gasping/apnea  HR < 100/min inspite of PPV  HR < 60/min  No adequate chest rise and no clinical improvement  If chest compressions are needed, intubation provides better coordination and efficacy of PPV  To administer drugs
  • 34.  Special conditions  Extreme Prematurity  Surfactant administration  Suspected diaphragmatic hernia
  • 35. Mechanism of action :  Increases systemic vascular resistance  Increases coronary artery perfusion pressure  Improves blood flow to myocardium and restores depleted ATP Indications :  If HR remains < 60/min even after 30 sec of effective ventilation preferably after intubation and at least another 45-60 sec of coordinated chest compressions and effective ventilation
  • 36. Administration :  Intravenous (recommended)  Endotracheal Preparation and dosage:  Adrenaline vial 1ml = 1mg (1:1000 solution)  Dilute with NS to make 1:10,000 solution (1ml = 100 mcg)  IV : 0.1-0.3 ml/kg = 10-30 mcg/kg  ET : 0.5 – 1 ml/kg = 50-100 mcg/kg  Give rapidly – as quickly as possible  Can repeat every 3-5 minutes
  • 37. Indications:  Bradycardia not improving with adrenaline Volume Expanders:  Normal saline (recommended)  Ringer lactate  Dosage: 10 ml/kg  Route : Umbilical vein  Rate: over 5-10 min , rapid infusion may cause IVH in <30 weeks babies
  • 38.  Additional resources , additional personnel, additional thermoregulation strategy  Portable warming pad  Polyethylene Plastic wrap (< 29wk)  Prewarmed transport incubator  Use of Oxymeter, blender to target Spo2 85%- 95%  Use Lower PIP 20-25 cm of H2O during PPV  Consider giving CPAP  Consider Surfactant
  • 39.  Avoid hyperthermia, consider therapeutic hypothermia within 6 hrs for >36wks and Acute perinatal HIE  Monitor for Apnea, bradycardia, BP, SPo2 &Urine output.  Monitor B. Sugars, electrolytes, Hematocrit , Platelets, ABG  Maintain adequate oxygenation & support ventilation as needed
  • 40.  Delay feeds, Start IV fluids, consider parenteral nutrition  Consider inotropes,fluid bolus  Ensure adequate ventilation before giving sodium bicarbonate(only in severe metabolic acidosis)
  • 41.  Choanal atresia – oral Airway  Pierre Robin : place prone , 12F Et through nose with tip in post pharynx  Laryngeal web, cystic hygroma, Cong. Goiter- ET/tracheostomy  Pneumothorax : Percutaneous needle aspiration  Pleural effusion : Percutaneous needle aspiration  Congenital Diaphragmatic hernia
  • 42.  Can we differ resuscitation?  Can we to stop resuscitation?