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Importance of treating iron deficiency anaemia in pregnancy

Importance of treating iron deficiency anaemia in pregnancy

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Importance of treating iron deficiency anaemia in pregnancy

  1. 1. Importance of Treating Iron Deficiency Anaemia in Pregnancy
  2. 2. Iron Deficiency Anaemia <ul><li>Iron Deficiency Anaemia Is the Most Prevalent Micronutrient Deficiency Affecting Just Over </li></ul><ul><li>2 BILLION </li></ul><ul><li>People Of the World. </li></ul>
  3. 3. WHO Mortality Data <ul><li>Around </li></ul><ul><li>0.8 MILLION </li></ul><ul><li>Deaths Are Attributed to </li></ul><ul><li>Iron Deficiency Each Year </li></ul>
  4. 4. WHO Mortality Data <ul><li>In Terms of the Loss of Healthy Life Years (Dalys), IDA Results in 25 MILLION </li></ul><ul><li>Dalys Lost Each Year. </li></ul>DALYs = Disability Adjusted Life Years The sum of years of potential life lost due to premature mortality and the years of productive life lost due to disability .
  5. 5. Economic Cost <ul><li>The Economic Cost of Iron Deficiency Is Huge Because It Decreases the PRODUCTIVITY And COGNITIVE Function </li></ul>
  6. 6. Economic Loss <ul><li>Annual Economic Loss Due to IDA in Four Countries of South Asia Namely Bangladesh, India, Pakistan and Sri Lanka Is </li></ul><ul><li>$4.2 Billion </li></ul><ul><li>With a loss of almost 0.6 % of its GDP due to IDA </li></ul>
  7. 7. Prevalence <ul><li>“ Almost </li></ul><ul><li>One Out of Two </li></ul><ul><li>Women of Child Bearing </li></ul><ul><li>Age Suffer From Anemia” </li></ul>National Institute Of Population Studies
  8. 8. Risk <ul><li>629 Pregnant Women Were Studied </li></ul><ul><li>313 Were (Hb <11 G/dl) Anaemic Group </li></ul><ul><li>316 Were (Hb >11 G/dl) Non-anaemic Group </li></ul><ul><li>For Anaemic Women </li></ul><ul><li>Preterm Delivery Was 4 Times Higher </li></ul><ul><li>LBW was 1.9 Times Higher </li></ul><ul><li>Risk of IUD Was 3.7 Times Higher </li></ul>Tropical Medicine and International Health vol9(4) 486–490 apr 04 Aga Khan University, Karachi, Pakistan
  9. 9. Folate Deficiency <ul><li>Folate Deficiency Causes </li></ul><ul><li>Neural Tube Defect (NTD) </li></ul><ul><li>to the Baby If the Pregnant Mother Has Low Folic Acid Status at the </li></ul><ul><li>TIME OF CONCEPTION </li></ul>
  10. 10. Developing Countries <ul><li>In Many Developing Countries the Women Even Do Not Know That She Is Having a Baby. </li></ul><ul><li>CDC Scientists Have Estimated That Every Year </li></ul><ul><li>500,000 Severe Birth Defects Are Caused by Folic Acid Deficiency. </li></ul>
  11. 11. Folic Acid In NTD <ul><li>Percentage of NTDs That Would Be Prevented </li></ul>
  12. 12. Ironur-IPS <ul><li>Is a compound containing </li></ul><ul><li>  </li></ul><ul><li>Iron Protein Succinylate </li></ul><ul><li>+ </li></ul><ul><li>Folic Acid </li></ul><ul><li>developed by Biocon. </li></ul>
  13. 13. Ironur-IPS <ul><li>Each 15 ml contains </li></ul><ul><li>Iron Protein Succinylate ………… 800 mg </li></ul><ul><li>Folic Acid ………………………………...5 mg </li></ul>
  14. 14. Iron Content <ul><li>Each 1 ml contain: 2.67 mg iron * </li></ul><ul><li>Each 5 ml contains: 13.33 mg iron * </li></ul><ul><li>Each 7.5 ml contain: 20 mg iron * </li></ul><ul><li>Each 10 ml contains: 26.67 mg iron * </li></ul><ul><li>Each 15 ml contain: 40 mg iron * </li></ul><ul><li>*elemental iron </li></ul>
  15. 15. Description <ul><li>Ironur IPS (Iron Protein Succinylate) Is an Iron Compound Specially Bonded to Chemically Modified Protein Casein (Milk Protein) in a Process Called Succinylation, Which Dramatically Stabilizes the Complex </li></ul>
  16. 16. Description
  17. 17. Efficacy BJOG. 2002 Sep;109(9):1009-14. Increase in Haemoglobin in Severe Anaemia in Pregnancy Iron Protein Succinylate + Folate Iron Protein Succinylate Haemoglobin Concentration g/dl P = 0.07
  18. 18. Efficacy <ul><li>  </li></ul>BJOG. 2002 Sep;109(9):1009-14. Increase in Haemoglobin in Overall Population of Pregnant Women Iron Protein Succinylate + Folate Iron Protein Succinylate Haemoglobin Concentration g/dl P < 0.001
  19. 19. Ironur IPS Vs IPC <ul><li>Ironur-ips Led Not Only to a </li></ul><ul><li>FASTER INCREASE </li></ul><ul><li>of Hemoglobin , Hematocrit , MCV , Serum Iron , and Ferritin Than Iron Hydroxide Polymaltose Complex, but the Laboratory Values Remained Higher in Group A (Ironur-IPS) Than in B (Iron Hydroxide Polymaltose Complex) even After 2 Months of Treatment. </li></ul>Int J Clin Pharmacol Ther. 1998 Jun;36(6):320-5.
  20. 20. Safety Profile <ul><li>Excellent Safety Profile in </li></ul><ul><li>93% Patients </li></ul>
  21. 21. Additional Benefits <ul><li>Ironur-IPS </li></ul><ul><li>Additional Folic Acid is present for additional benefits </li></ul><ul><li>Free From </li></ul><ul><li>Sodium & Potassium and Sugar </li></ul>
  22. 22. Who Needs Ironur IPS <ul><li>Where demands of iron is increased </li></ul><ul><ul><li>Women, especially those with the history of child bearing challenges </li></ul></ul><ul><ul><li>People with diets that are low in both meat and ascorbic acid </li></ul></ul><ul><ul><li>Elderly </li></ul></ul><ul><ul><li>Who donate blood more than 3 times a year </li></ul></ul><ul><ul><li>Growing children </li></ul></ul>
  23. 23. Why Ironur IPS <ul><li>Unsurpassed Efficacy </li></ul><ul><li>Excellent gastric tolerability </li></ul><ul><li>Improved Absorption </li></ul><ul><li>Additional benefits of Folic Acid </li></ul><ul><li>Superior Safety Profile </li></ul>
  24. 24. Doses <ul><li>Adults: </li></ul><ul><li>15 – 30 ml /day </li></ul><ul><li>Children: </li></ul><ul><li>1.5 ml/Kg/day in 2divided doses   </li></ul>

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