1. The European Research Infrastructure for Biobanking and Biomolecular Resources (BBMRI): Preparatory Phase and European Context Eero Vuorio, University of Turku, Finland September 2009 Preparatory Phase Grant Agreement 212111
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7. The pan-European Scale of BBMRI 183 Associated organisations 28 Countries 50 Participating institutions Preparatory phase 27 months Funding 5 mio €
8. Key Components of BBMRI Fam. history Lab. param. Treatm. outcome Lifestyle PBMC Serum FFPE tissues Frozen tissues Cells Antibodies Affinity binders Recomb. proteins Gene clone collections* siRNA libraries* Cell lines* Model organisms* Sample storage Human biological samples and data Healthy Population Patients Analysis tools Application Basic research Life sciences Targets for Drug discovery Biomarkers for Drug development New diagnostics Personalized medicine Public health Infrastructure Data storage Biocomputing DNA * : ESFRI BMS report but not funded
9. Possible Legal Structure of BBMRI (ERIC) Distributed hub and spoke structure National members Biobanks Biomolecular res. Technology centers Associated partners Hospitals Universities Service providers … Secretariat (statutory seat)
10. Organization (prep phase) Governance council (participants, ass. organizations) Executive Management Disease-oriented Biobanks WP3 Biomolecular resources Technologies WP4 Data bases Biocomputing WP5 Advisory board Stakeholder forum Funders Patients Clinicians Industry Partners Users Science Industry ELSI E L S I WP6 Population-based Biobanks WP2 Participants Participants Funding Financing WP7 Participants Coordination board (external projects) Project Management WP1 Steering committee (WP leaders, chairs) Strategic Executive Operative Participants Participants Participants Participants
11. The BBMRI Team: WP Leaders and Chairs Coordination/Executive Mgmnt. K. Zatloukal, AT; E. Vuorio, FI M. Yuille, UK; M Pasterk, FR Population-based Biobanks: L. Peltonen, FI/UK; A. Metspalu,EE Disease-oriented Biobanks: E. Wichmann, GER, T Meitinger, GER Biomolecular Resources: U. Landegren, SE; M. Taussig, UK Databases & Biocomputing: J-E Litton, SE Ethical, Legal and Societal Issues: A. Cambon-Thomsen, FR Funding and Financing: G. Dagher, FR; J. Ridder, NL C. Brechot, FR; Governance Council Chair: L. Peltonen, FI Advisory Board Chair: G-J van Ommen, NL Coordination Board Chair: K. Zatloukal, AT Stakeholder Forum Chair: M. Griffith, IR 51 Participants (6 Ministries, 18 Funding Organizations) 210 Associated Organizations 30 Countries
12. Synergies of BMS Research Infrastructures EATRIS ELIXIR INFRAFRONTIER ECRIN BBMRI INSTRUCT Target Id Target Val Hit Lead Lead Optim Preclininc Phase I Phase II Research Discovery Development Phase III e-Infrastructure EMBRC EISBI EU Open Screen Euro Bio- Imaging BSL4 Laboratories B i o b a n k i n g B i o i n f o r m a t i c s PP projects 1st update of roadmap Emerging infrastructures
13. The New Dimension in Life Sciences Research networks networks networks resources, technologies services Individual research groups pan-European research infrastructures Access Competition Innovation Collaboration Integration Harmonization Innovation circle
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