This year’s panel features programs noteworthy in their approach to biotechnology/biomanufacturing education and training and the workforce. Panelists include leaders of the Lone Star Biotechnology Institute at Lone Star College working with the local biomedical and biofuels industry in Houston, TX; the Biomass Production Training Certificate at Mira Costa College part of the EDGE (Educating and Developing Workers for the Green Economy) initiative for San Diego County, CA; the SoCalBio Biomanufacturing Consortium to develop biomanufacturing technician education and training programs to support the maturation of the industry in Los Angeles/Orange Counties, CA; and a new program, Biotechnology and Compliance, focusing on biomanufacturing and partnered with local industry at Quincy College in Quincy, MA
2. Partnerships
Community colleges traditionally have been tasked to
support local industry by providing apt education and
training for their industries.
Key to this role are academia-industry partnerships and
grants that support the development of such strategic
alliances (NSF ATE and DOL ETA grants, for instance).
Research questions that arise to understand these
relationships are:
What are the characteristics of effective partnerships and
collaborations?
How are they developed and how are they sustained?
3. NBC2 Partnerships Case Study
12 partners were interviewed by Dr. Joanna Kile,
their conclusions were:
Have a product and stay focused on delivering it.
Partnerships exist in the relationship: the more points of connection
the stronger the relationship
Build trust by committing and then following through
Recognize that a successful partnership is a long-term commitment
Identify champions within the group
Solicit the opinion of all partners
Be prepared to give more than to receive
Share your success stories
Forget what you have done in the past; find out what you need in
order to be in business five years from now.
4. NBC2 Biomanufacturing
Products
GBC Laboratory Manual generic and customized
Introduction to Biomanufacturing textbook
Biofuels Production and Analysis textbook and lab manual
Protein is Cash Teachers Workshop
BIOMAN Annual Conference
Adult 360hr/12wk Biomanufacturing Certificate
Hybrid post-baccalaureate 120hr/15wk BIOMAN Certificate
Future = modular curriculum to suit local biomanufacturing
needs; provision of supplies for teaching the modules
6. Panelists Introduction
Danny Kainer from Lonestar Community
College in Houston, TX
Bruce Van Dyke from Quincy College in
Quincy, MA
Steve Dahms from SoCalBio in Los
Angeles/Orange Counties, CA
7. A thumbnail sketch of
our college system
• Opened in 1973 (as North Harris College) with an
enrollment of 613 students and 15 staff members
• Is now the 2nd largest
community college
system in Texas
• ~80,000 credit students;
>90,000 if one includes
CE!
• The LSC System covers
over 1,400 square miles
& includes 11 member
school districts!
8. My personal
favorite…
LSC-Montgomery
• >13,000 students
• Only biotechnology program in
the LSC system, which is the
oldest in the state & is recognized by
TSSB
48. First Things First
• College Performs a Gap Analysis – What is missing
Type of training
Research (biomedical, environmental, biofuels)
Manufacturing (drugs, medical devices)
Will the college support the program?
Financially
Faculty Support
• Primary Purpose of the Program
Get students job after completing the program?
Prepare them to transfer to a university to obtain a B.S.
49. • Make sure the program aligns with industry needs
You can’t do this on your own
What state and local organizations track biotechnology
• Focus the program – Do not dilute student learning
by being to broad based
• Corporate Partners – Who you know and who they know
The primary way of getting in the door
This opens the door to internships
• Incumbent worker training – Short Courses
Expanding your student base
State and local biotechnology initiative grants
50. The most surprising aspect of
starting the Biotechnology &
Compliance program
The willingness of companies to work with me on every
aspect of the program and to make commitments of time
and resources to enable the program to produce competent
students ready to enter the workforce.
51. Developing New Workforce Training Programs and Platforms: The Catalytic
Role of Bioscience Trade Associations in Defibrillating Companies, College
Administrators and Faculty, WIBs, 1-Stop Centers and Government Agencies
A. Stephen Dahms
President and CEO Emeritus, Alfred E. Mann Foundation
Vice President Academic, Industry and Government Affairs, So. California Biomedical Council Member
Federal Emerging Technology and Research Advisory Committee
52. Eye-balling and Traversing the Bioscience Industries
Workforce Development Arena
-Observations Over the Past 15 Years-
53. SEC Disclaimer
Chair, WF/Education Committees 1995-2006 (BODs)
– BIOCOM, BayBio, SoCalBio
– California Healthcare Institute
– Addressed the full span of regional WF development
activities -> national and international level, including the
medical device arena (AdvaMed)
Chair, BIO WF Development Committee 1996-2007 (BIO/ECS
BOD and BOD Committees 1994-2008)
– DOC, DOE, NSF, DOL, NIH, BLS, GAO, Beltway groups
– House and Senate Science/Labor Committees
– NRC/NAS/IOM/NAE: GUIRR, Federal Demonstration Pship
– International organizations: EU and OECD (1998-2008)
– Professional scientific societies
– H1B visas, Skills Standards, training needs (#s and areas)
55. onstellation of Actors in the Theater
Workforce Development
City WIB
City DD
DOL County
County DD
WIB
DOE ????? 1-Stop
1-Stop CC
Centers
Centers District
NSF/NIH State
EDD State CC
DOC
Office
Cos &
Non-
Profits
56. Research and Information,
Manufacturing Technical Sales and
Product
and Production Affairs
Finance and
Development Marketing
Administration
57. Research and Information,
Manufacturing Technical Sales and
Product
and Production Affairs
Finance and
Development Marketing
Administration
58. Layers of Complexity
Cities
Cities
DOL CDDs CountieWIBs
Counties
s WIBs
DOE ????? CCDs
X1
X1 CC
-Stop
-Stop District
NSF/NIH State Centers
Centers
EDD State CC
DOC
Office
Cos &
Non-
Profits
60. Trade Organizations to the Rescue!
Cities
City DD
DOL CountieWIBs
Counties
s WIBs
DOE T-ORG CCDs
X1
X1 CC
-Stop
-Stop District
NSF/NIH State Centers
Centers
EDD State CC
DOC
Office
Cos &
Non-
Profits
61. The Trade Organization: Integrator of
Regional Inputs to Build Industry Clusters
Intellectual
Capital
Financial
Human Capital
Capital
Regional Integrator
Industry Cluster Industry Cluster
63. T-ORGS: a WF development
coordinator, organizer, catalyst
and nucleating device…often a
defibrillator City WIB
City DD
DOL County
County DD
WIB
T-ORGs
DOE 1-Stop
1-Stop CC
Centers
Centers District
NSF/NIH State
EDD State CC
DOC
Office
Non-
Profits
64. Problems Facing T-ORGs in WF Development
-Cities and Counties-
• Often naïve understanding of the playing field by the players:
understanding of technology…some still bemoaning the loss
of the buggy-whip industry
• Layers of complexity…especially in megacities
• Pre-existing, high-walled political bailiwicks
• Historical partnering among the players and segmentation
difficult to change: breaking up the “party”…divorces are
difficult
• Time-lines for completion of projects: triage vs. long-term
solutions
• “Project Product”: sustainability vs. triage
• Players lack of understanding of the necessary resources
65. Problems Facing T-ORGs in WF Development
-Cities and Counties-
• Unreasonable expectations of the WF development arena
regarding companies
• CC’s: administrators, role of non-academic training
operations, multiple CC’s aiming for the same targets,
unrealistic expectations of companies, survey impacts, moving
off the “molecular biology” raison d’etre dime
• T-ORG BOD’s: regional, state, and national
• 2-year -> 4-year institutional programs: regionally-approved,
industry validated layered, stackable certificates
• Research universities: often a considerable problem:
understanding the critical role of CC’s, intrusion into CC space,
sparse laboratory training in some universities
• A battle of wills…and entrenched public service organizations
very adept at survival
68. WIB, etc. & Naïve Understanding of the Biotech Industry
1985 1990
Recomb Monoclonal Recomb Monoclonal
DNA Antibodies DNA Antibodies
Small Gene
Antisense Molecules Therapy
69. Complexity of the Biotech Industry 2009
-27 Years after 1986-
DNA-based
computation
Bioinformatics
(Data management &
Data mining)
Proteomics- Computational
expression analysis drug design
Genetic Novel
Profiling Pharmacogenomics chemistries
Micro-arrays & Biosensors Gene Anti-sense
nanotechnologies therapy RNAi, etc.
High
Combinatorial throughput Recombinant MAbs& phage
chemistry screening DNA technologies display
Multiplexed Array of Technologies
75. Regulatory Affairs Clinical Affairs
Quality Built into core business courses for all
center degrees
5.0 FDA Compliance 3.3 Optimizing of chromatographic techniques
4.5 IND, NDA and other regulatory submissions 3.3 Pharmacokinetics
4.5 cGMP, GCP and GLP 3.3 Pharmacodynamics
4.2 Clinical trial design and modeling 3.3 Drug discovery-Conventional & rational drug design
4.1 Technical writing 3.3 Functional genomics
4.1 cGMP documentation 3.3 Proteomics
4.1 Process validation 3.3 Small molecule manufacturing & scale-up issues
4.0 Project management 3.3 Toxicology and toxicokinetics
4.0 Team-based approaches 3.3 Sterilization
4.0 Analytical methods development and validation 3.2 Facility design
4.0 Materials and document control 3.2 Principles of industrial hygiene
4.0 cGMP training 3.2 Biotechnology and drug design
3.9 Quality and production 3.2 General pharmaceutical science
3.9 Regulatory strategies and negotiation 3.2 Design controls
3.9 Clinical trial statistical analysis 3.2 Facility management
3.9 Principles of information systems 3.2 Basic biochemical engineering
3.8 Clinical data management 3.2 Combinatorial chemistry
3.8 Implementation of clinical trials 3.1 Pharmaceutical delivery systems
3.8 Control systems 3.1 Manufacturing execution systems
3.8 Clinical trials administration 3.1 Separation and purification
3.8 Team-based approaches in biotech. dev. & production 3.1 Protein stability and formulation
3.8 cGMP audits 3.0 Statistical process control
3.7 International regulatory affairs and ISO-9000 3.0 Pharmacoeconomics
3.7 Systems documentation 3.0 Manufacturing personnel training
3.6 Facility validation 2.9 Instrumentation in downstream monitoring
3.6 Global CMC (chemistry, manufacturing and control) 2.9 Bio/pharmaceutical technology mgmt.
3.6 Clinical trials audits 2.9 Mgmt. of development & tech.-based innovation
3.5 Corporate partnering 2.8 Combinatorial biology
3.5 Regulatory affairs professional training 2.8 Bio/pharmaceutical marketing
3.5 CRA training 2.8 Computers in bioprocess engineering
3.5 Process development strategies 2.8 Mammalian cell perfusion reactors
3.5 Bioinformatics 2.7 Fermentation strategies
3.5 Good statistical practices in drug development 2.7 Drug release technology
3.5 Statistical process control 2.6 Robotics in drug discovery
3.4 Hazardous waste management 2.6 Mgmt. & organizational behavior
3.4 Electronic document management and submissions 2.4 Biochemical reactor design & configuration
3.4 Pharmaceutical formulation and stability 2.3 Intelligent biomanufacturing
3.4 Pharmacogenetics
3.4 Computer and software validation
3.4 Communications
3.4 Manufacturing process technologies
3.4 Operation scheduling
76. Points of Attack of T-ORGs in WF Development
“Sector Intermediary Role”
-Cities and Counties-
• Facilitating an increased understanding of the playing field
• Removing layers of complexity…especially in megacities
• Circumventing or removing high-walled political bailiwicks
• Expanding partnering among the technologically-naïve players
• Encouraging departure from total reliance on triage approaches
• Demanding sustainability
• Educating the players on the true costs of training in the 21 st century
• Embracing CC administrators and engaging them in solutions
• Catalyzing applied research and manufacturing programs: faculty training
• Stimulation of specialized training facilities, especially in the megacities
• Education of T-ORG boards of directors
• Creating regionally-approved, industry validated layered, stackable
certificates
• Constant education of the research universities
• Outreach to federal agencies
• Triage of the DOL
77. Problems Facing T-ORGs
-Operating In the Sphere of the DOL, one person’s experiences-
• Hooray…T-ORGs are recognized as
Sector Intermediaries, but...there are
DOL focal problems
– Little DOL concept of need for
sustainability
– Little DOL concept of training costs
– Entry-level employee predominant
focus
– Reorientation of Congressional
mandates
– “Spread the Geld” political mentality
– Reviewers: Invaders from Planet X
• Underdeveloped appreciation of true
vs. interpolated WF needs
– H1B Training Skills RFP case in point
79. H1B’s in the Biotechnology Industry
2000-2007
• 6-10% of the biotech WF = 18,000
• 80% passed through US higher education
• Degrees: in red, composition of the US biotech WF
– 40% PhD (19%)
– 35% MS (17%)
– 20% BS (50%)
– 5% MD
– 0% AA/AS/vocEd (14%)
• 85% acquired permanent residency ($150M)
• And the role of the DOL is exactly what in addressing this
dependency upon foreign nationals?
80. What is/was the DOC Thinking? Is it really
making the H1B problem go away…or is there
another agenda at work?….
81. Trade Organizations to the Rescue!
Cities
City DD
DOL CountieWIBs
Counties
s WIBs
DOE T-ORG CCDs
X1
X1 CC
-Stop
-Stop District
NSF/NIH State Centers
Centers
EDD State CC
DOC
Office
Cos &
Non-
Profits
82. T-ORGs: A Firm Foundation on Which to
Coordinate and Facilitate Workforce
Development
Editor's Notes
The NBC2 is the subject of a PhD dissertation by Joanna Kile entitled, ‘Exploring Industry Perceptions of Factors Influencing the Development and Sustainability of Academia-Industry Advanced Technological Education Partnerships’.