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Dr. Vijay Marakala, MBBS, MD.
Assistant professor
BIOCHEMISTRY
SIMS & RC
Fatty acids are carboxylic acids with
hydrocarbon side chain
R COOH
Esterified
• Esterified with various lipids
• Common
Free
• FFA
• Blood
Occurrence
D/U Total no of
carbon atoms
Even chain FA
Odd chain FA
D/U Length of
hydrocarbon chain
Short chain FA
Medium chain FA
Lon...
Most of the fatty acids that occur in natural lipids are
even carbons.
Propionic acid
• 3 Carbon
Valeric acid
• 5 Carbon
Seen in milk and microbial cell walls
In which hydrocarbon side chain is saturated (no double bonds).
Monounsaturated
FA
• One double bond
Polyunsaturated FA
• 2 or more double
bonds
Subclassified according to number of doub...
Numbering of carbon atoms in FA
Carboxyl endMethyl end
Palmitic acid
Nomenclature of Fatty Acids
Saturated FA have both trivial names and systematic names.
Nomenclature of Fatty Acids
They have trivial names, systematic names, ω-end
names and shorthand forms.
Representation of double bonds of FA 2 systems
1. C-
System
2. ω-or n-
System
Nomenclature of Fatty Acids
1. C-System
2. ω-or n-System
ESSENTIAL FATTY ACIDS
Functions of EFA
1.Synthesis of Ecosanoids
2.Maintenance of structural integrity of
cells
3.Development of retina and brai...
Thromboxanes
Leukotrienes Prostaglandins
EFA deficiency
The syndrome in humans characterized by
Horny eruptions on the posterior and lateral
parts of limbs, on th...
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
Chemistry of lipids fatty acids ppt BIOCHEMISTRY
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Chemistry of lipids fatty acids ppt BIOCHEMISTRY

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Chemistry of lipids fatty acids ppt BIOCHEMISTRY

  1. 1. Dr. Vijay Marakala, MBBS, MD. Assistant professor BIOCHEMISTRY SIMS & RC
  2. 2. Fatty acids are carboxylic acids with hydrocarbon side chain R COOH
  3. 3. Esterified • Esterified with various lipids • Common Free • FFA • Blood Occurrence
  4. 4. D/U Total no of carbon atoms Even chain FA Odd chain FA D/U Length of hydrocarbon chain Short chain FA Medium chain FA Long chain FA Very long chain FA D/U Nature of hydrocarbon chain Saturated FA Unsaturated FA Branched chain FA Hydroxy FA
  5. 5. Most of the fatty acids that occur in natural lipids are even carbons.
  6. 6. Propionic acid • 3 Carbon Valeric acid • 5 Carbon Seen in milk and microbial cell walls
  7. 7. In which hydrocarbon side chain is saturated (no double bonds).
  8. 8. Monounsaturated FA • One double bond Polyunsaturated FA • 2 or more double bonds Subclassified according to number of double bonds
  9. 9. Numbering of carbon atoms in FA Carboxyl endMethyl end Palmitic acid
  10. 10. Nomenclature of Fatty Acids Saturated FA have both trivial names and systematic names.
  11. 11. Nomenclature of Fatty Acids They have trivial names, systematic names, ω-end names and shorthand forms.
  12. 12. Representation of double bonds of FA 2 systems 1. C- System 2. ω-or n- System Nomenclature of Fatty Acids
  13. 13. 1. C-System 2. ω-or n-System
  14. 14. ESSENTIAL FATTY ACIDS
  15. 15. Functions of EFA 1.Synthesis of Ecosanoids 2.Maintenance of structural integrity of cells 3.Development of retina and brain 4.Antiatherogenic effect
  16. 16. Thromboxanes Leukotrienes Prostaglandins
  17. 17. EFA deficiency The syndrome in humans characterized by Horny eruptions on the posterior and lateral parts of limbs, on the back and buttocks. Dermatitis Poor wound healing Phrynoderma

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