This is a lecture focused on differentiating the traditional curriculum and the inquiry-based approach in laboratory teaching. This talk was delivered in the plenary session of the Regional Science Competency, Instructional Empowerment, and Capability Enhancement (SCIENCE) Training (Series I) at DMMMSU-SLUC, Agoo, La Union, sponsored by the DEpED Division of La Union, Provincial Government of La Union, Municipality of Agoo, DMMMSU-SLUC College of Graduate Studies and College of Arts and Sciences.