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OESOPHAGEAL
MOTILITY
DISORDERS
Pain with or with out
swallowing.usually
intermittent
Associated with GORD
or a part of diffuse GI
motility disorders
Barium impregnated
food bolus seen to
stick to oesophagus
 DISORDERS OF PHARYNGO-OESOPHAGEAL JN
 Neurological-stroke ,motor neurone ds
,multiple sclerosis,parkinsons ds.
Myogenic-myasthenia gravis,mus dystrophy
Pharyngo-oesophageal(zenkers) diverticulum
DISORDERS
OF BODY OF
OESOPHAGUS
DIFFUSE
OESOPHAGEAL
SPASM
NUT CRACKER
OESOPHAGUS
 AUTOIMMUNE DISORDERS-ESPECIALLY
SYSTEMIC SCLEROSIS(CREST-
calcinosis,raynaud’s synd,esoph motility
disorders,sclerodactyly,telangiectasia)
 REFLEX ASSOCIATED
 IDIOPATHIC
ALLER
GIC
EOSINOPHILIC
OESOPHAGITIS
NON SPECIFIC
OESOPHAGEAL
DYSMOTILITY
 ACHALASIA
 INCOMPETENT LOWER OESOPHAGEAL
SPHINCTER(GORD)
 LOSS OF GANGLION CELLS IN MYENTERIC
PLEXUS IN LOWER OESOPHAGUS
 DILATATION , TORTUOSITY $ HYPERTROPHY
OF PROXIMAL OESOPHAGEAL SEGMENT
 HISTOLOGY -REDUCTION IN NO: OF GANGLION
CELLS WITH VARIABLE DEGREE OF C/C INFLMTN
 VIGOROUS ACHALASIA-NORMAL NO: OF
GANGLION CELLS WITH INFLMTN AND NEURAL
FIBROSIS
 AETIOLOGY:IDIOPATHIC, ASSOC WITH CHAGAS
DS,STRESS $ EMOTIONAL FACTORS, VIT DEF
 WOMEN AROUND 30-40 YRS COMMONLY
AFFECTED M:F=2:3
 DYSPHAGIA MAINLY FOR LIQUIDS
 RECCURENT RESP TRACT INFN
 COMPLICATIONS-INCREASED INCIDENCE OF
CARCINOMA
 Achalasia like usually produced by
adenocarcinoma of cardia and also by benign
tumors at this level
 Inability of sphincter to relax is due to
absent body peristalsis
 Also seen in carcinoma of bronchus $
pancreas
1. BARIUM SWALLOW-uniform dilated oesph above
with tapering segmet below(BIRDS BEAK)
2. Oesophagoscopy-tight cardia and food residue
in oesophagus
3. PLAIN X-RAY ABD ERECT-ABSENTGASTRIC GAS
BUBBLE
4. Lower oesophageal sphincter pressure may be
increased
5. Oesophageal manometry:show simultaneous contrn
of oesoph body $ incomplete relxn of los
Forceful dilatation of
cardia:stretching of cardia with
balloon to disrupt muscle and render it
less competent.balloons of 30-40 mm
diameter inserted over guideline.
Hellers myotomy:it involves cutting
muscle of lower oesophagus and
cardia.used after failed dilatation.90%
success
 Botulinum toxin:interfere with cholinergic
excitatory neural activity at LOS.effect is
permanent so repeated for months.used in
elderly.
DRUGS:relieve symptoms.CALCIUM CHANNEL
BLOCKERS:Nifedipine S/L
Oesophageal motility disorders
Oesophageal motility disorders

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Oesophageal motility disorders

  • 2. Pain with or with out swallowing.usually intermittent Associated with GORD or a part of diffuse GI motility disorders Barium impregnated food bolus seen to stick to oesophagus
  • 3.  DISORDERS OF PHARYNGO-OESOPHAGEAL JN  Neurological-stroke ,motor neurone ds ,multiple sclerosis,parkinsons ds. Myogenic-myasthenia gravis,mus dystrophy Pharyngo-oesophageal(zenkers) diverticulum
  • 5.  AUTOIMMUNE DISORDERS-ESPECIALLY SYSTEMIC SCLEROSIS(CREST- calcinosis,raynaud’s synd,esoph motility disorders,sclerodactyly,telangiectasia)  REFLEX ASSOCIATED  IDIOPATHIC
  • 7.  ACHALASIA  INCOMPETENT LOWER OESOPHAGEAL SPHINCTER(GORD)
  • 8.  LOSS OF GANGLION CELLS IN MYENTERIC PLEXUS IN LOWER OESOPHAGUS  DILATATION , TORTUOSITY $ HYPERTROPHY OF PROXIMAL OESOPHAGEAL SEGMENT  HISTOLOGY -REDUCTION IN NO: OF GANGLION CELLS WITH VARIABLE DEGREE OF C/C INFLMTN  VIGOROUS ACHALASIA-NORMAL NO: OF GANGLION CELLS WITH INFLMTN AND NEURAL FIBROSIS  AETIOLOGY:IDIOPATHIC, ASSOC WITH CHAGAS DS,STRESS $ EMOTIONAL FACTORS, VIT DEF
  • 9.
  • 10.  WOMEN AROUND 30-40 YRS COMMONLY AFFECTED M:F=2:3  DYSPHAGIA MAINLY FOR LIQUIDS  RECCURENT RESP TRACT INFN  COMPLICATIONS-INCREASED INCIDENCE OF CARCINOMA
  • 11.  Achalasia like usually produced by adenocarcinoma of cardia and also by benign tumors at this level  Inability of sphincter to relax is due to absent body peristalsis  Also seen in carcinoma of bronchus $ pancreas
  • 12. 1. BARIUM SWALLOW-uniform dilated oesph above with tapering segmet below(BIRDS BEAK) 2. Oesophagoscopy-tight cardia and food residue in oesophagus 3. PLAIN X-RAY ABD ERECT-ABSENTGASTRIC GAS BUBBLE 4. Lower oesophageal sphincter pressure may be increased 5. Oesophageal manometry:show simultaneous contrn of oesoph body $ incomplete relxn of los
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18. Forceful dilatation of cardia:stretching of cardia with balloon to disrupt muscle and render it less competent.balloons of 30-40 mm diameter inserted over guideline.
  • 19.
  • 20. Hellers myotomy:it involves cutting muscle of lower oesophagus and cardia.used after failed dilatation.90% success
  • 21.
  • 22.  Botulinum toxin:interfere with cholinergic excitatory neural activity at LOS.effect is permanent so repeated for months.used in elderly. DRUGS:relieve symptoms.CALCIUM CHANNEL BLOCKERS:Nifedipine S/L