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NUCLEAR MAGNETIC RESONANCE
SPECTROSCOPY
Presented By
Mrs.Smita P.Shelke
Assistant Professor, Department of Pharmaceutical Chemistry,
GES’s Sir Dr.M.S.Gosavi College of Pharmaceutical Education and
Research, Nashik-05.(Maharashtra
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Introduction
Nuclear Magnetic Resonance (NMR) is a spectroscopy technique which is based on the absorption of electromagnetic
radiation in the radio frequency region 4 to 900 MHz by nuclei of the atoms.
Proton Nuclear magnetic resonance spectroscopy is one of the most powerful tools for elucidating the number of hydrogen
or proton in the compound.
It is used to study a wide variety of nuclei:
• 1H 15N • 19F 19F •13C 31P
Theory of NMR
Spin quantum number (I) is related to the atomic and mass number of the nucleus.
Elements with either odd mass or odd atomic number have the property of nuclear “spin”.
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H-NMR spectrum of Ethyl Bromide and Propyl Bromide
H-NMR spectrum of Ethanol
H-NMR spectrum of Benzene
H-NMR spectrum of Benzoic acid
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Example: Splitting in ethyl acetate
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Nmr sps.pptx