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THE CARDIAC CYCLE
Dr.Riyas A
Dr SMCSI
Mechanical events
Events in late diastole
Atrial systole
Ventricular systole
Early diastole
LATE DIASTOLE
ATRIAL
SYSTOLE
ISOMETRIC VENTRICULAR
CONTRACTION
VENTRICULAR
EJECTION
ISOMETRIC
VENTRICULAR
RELAXATION
THE CARDIAC CYCLE
DIASTOLE
Late diastole
 A-V valve ie;tricuspid and mitral valve
opens
 Semilunar valve ie; pulmonary and aortic
valves are closed
 Heart flows in to the diastole ,filling the
atria and ventricle
 The rate of filling declines as the ventricle
become distended
ATRIAL SYSTOLE
The end of diastole
Atrial systole
 Contraction of blood propels some
additional blood in to the ventricle but 70%
of the blood filling passively
 Contraction of atria produce narrowing of
svc and I v c pulmonary vein orifices and
prevent back flow but however some blood
will regurgitate in to the vein and produce A
wave
ATRIAL SYSTOLE - Heart
 Prior to atrial systole, blood has been
flowing passively from the atrium
into the ventricle through the open
AV valve.
 During atrial systole the atrium
contracts and tops off the volume in
the ventricle with only a small
amount of blood. Atrial contraction
is complete before the ventricle
begins to contract.
ATRIAL SYSTOLE
Pressures & Volumes
 The "a" wave occurs when the atrium
contracts, increasing atrial pressure
(yellow).
 Blood arriving at the heart cannot
enter the atrium so it flows back up
the jugular vein, causing the first
discernible wave in the jugular
venous pulse.
 Atrial pressure drops when the atria
stop contracting.
 During atrial systole the atrium
contracts and tops off the volume in
the ventricle with only a small
amount of blood.
 Atrial contraction is complete before
the ventricle begins to contract.
ATRIAL SYSTOLE
ECG
 An impulse arising from the SA node results in depolarization and
contraction of the atria (the right atrium contracts slightly before the left
atrium).
 The P wave is due to this atrial depolarization.
 The PR segment is electrically quiet as the depolarization proceeds to the
AV node.
 This brief pause before contraction allows the ventricles to fill completely
with blood.
ATRIAL SYSTOLE
Heart Sounds
 A fourth heart sound (S4) is abnormal and is associated with the end of
atrial emptying after atrial contraction.
 It occurs with hypertrophic congestive heart failure, massive pulmonary
embolism, tricuspid incompetence, or cor pulmonale.
ISOVOLUMETRIC
CONTRACTION
The Beginning of systole
ISOVOLUMETRIC CONTRACTION
Heart
 The atrioventricular (AV) valves
close at the beginning of this phase.
 Electrically, ventricular systole is
defined as the interval between the
QRS complex and the end of the T
wave (the Q-T interval).
 Mechanically, ventricular systole is
defined as the interval between the
closing of the AV valves and the
opening of the semilunar valves
(aortic and pulmonary valves).
ISOVOLUMETRIC CONTRACTION
Pressures & Volumes
 The AV valves close when the
pressure in the ventricles (red)
exceeds the pressure in the atria
(yellow).
 As the ventricles contract
isovolumetrically -- their volume
does not change (white) -- the
pressure inside
increases, approaching the pressure
in the aorta and pulmonary arteries
(green).
ISOVOLUMETRIC CONTRACTION
ECG
 The electrical impulse propagates from the AV node through the His bundle
and Purkinje system to allow the ventricles to contract from the apex of the
heart towards the base.
 The QRS complex is due to ventricular depolarization, and it marks the
beginning of ventricular systole. It is so large that it masks the underlying
atrial repolarization signal. the ventricles to fill completely with blood.
ISOVOLUMETRIC CONTRACTION
Heart Sounds
 The first heart sound (S1, "lub") is due to the closing AV valves and
associated blood turbulence.
RAPID EJECTION
RAPID EJECTION
Heart
 The semilunar (aortic and
pulmonary) valves open at the
beginning of this phase.
RAPID EJECTION
Pressures & Volumes
 While the ventricles continue
contracting, the pressure in the ventricles
(red) exceeds the pressure in the aorta
and pulmonary arteries (green); the
semilunar valves open, blood exits the
ventricles, and the volume in the
ventricles decreases rapidly (white).
 As more blood enters the
arteries, pressure there builds until the
flow of blood reaches a peak.
 The "c" wave of atrial pressure is not
normally discernible in the jugular
venous pulse. Right ventricular
contraction pushes the tricuspid valve
into the atrium and increases atrial
pressure, creating a small wave into the
jugular vein. It is normally simultaneous
with the carotid pulse.
RAPID EJECTION
ECG
 No Deflections
RAPID EJECTION
Heart Sounds
 None
REDUCED EJECTION
The end of systole
REDUCED EJECTION
Heart
 At the end of this phase the
semilunar (aortic and pulmonary)
valves close.
REDUCED EJECTION
Pressures & Volumes
 After the peak in ventricular and
arterial pressures (red and
green), blood flow out of the
ventricles decreases and ventricular
volume decreases more slowly
(white).
 When the pressure in the ventricles
falls below the pressure in the
arteries, blood in the arteries begins
to flow back toward the ventricles
and causes the semilunar valves to
close. This marks the end of
ventricular systole mechanically.
REDUCED EJECTION
ECG
 The T wave is due to ventricular repolarization. The end of the T wave
marks the end of ventricular systole electrically.
REDUCED EJECTION
Heart Sounds
 None
ISOVOLUMETRIC
RELAXATION
The beginning of Diastole
ISOVOLUMETRIC RELAXATION
Heart
 At the beginning of this phase the
AV valves are closed.
ISOVOLUMETRIC RELAXATION
Pressures & Volumes
 Throughout this and the previous two
phases, the atrium in diastole has
been filling with blood on top of the
closed AV valve, causing atrial
pressure to rise gradually (yellow).
 The "v" wave is due to the back flow
of blood after it hits the closed AV
valve. It is the second discernible
wave of the jugular venous pulse.
 The pressure in the ventricles (red)
continues to drop.
 Ventricular volume (white) is at a
minimum and is ready to be filled
again with blood.
ISOVOLUMETRIC RELAXATION
ECG
 No Deflections
ISOVOLUMETRIC RELAXATION
Heart Sounds
 The second heart sound (S2, "dup") occurs when the semilunar (aortic
and pulmonary) valves close. S2 is normally split because the aortic
valve closes slightly earlier than the pulmonary valve.
RAPID VENTRICULAR
FILLING
RAPID VENTRICULAR FILLING
Heart
 Once the AV valves open, blood that
has accumulated in the atria flows
rapidly into the ventricles.
RAPID VENTRICULAR FILLING
Pressures & Volumes
 Ventricular volume (white) increases
rapidly as blood flows from the atria
into the ventricles.
RAPID VENTRICULAR FILLING
ECG
 No Deflections
RAPID VENTRICULAR FILLING
Heart Sounds
 A third heart sound (S3) is usually abnormal and is due to rapid
passive ventricular filling. It occurs in dilated congestive heart
failure, severe hypertension, myocardial infarction, or mitral
incompetence.
REDUCED VENTRICULAR
FILLING
(Diastasis)
REDUCED VENTRICULAR FILLING
Heart
 Rest of blood that has accumulated in
the atria flows slowly into the
ventricles.
REDUCED VENTRICULAR FILLING
Pressures & Volumes
 Ventricular volume (white) increases
more slowly now. The ventricles
continue to fill with blood until they
are nearly full.
REDUCED VENTRICULAR FILLING
ECG
 No Deflections
REDUCED VENTRICULAR FILLING
Heart Sounds
 None
THE COMPLETE PICTURE
CARDIAC CYCLE
AtrialSystole
Mitral
Closes
Isovolumiccontract.
Aortic
opens
S1
RapidEjection
ReducedEjection
IsovolumicRelax.
Aortic
closes
RapidVentricular
Filling
Mitral
opens
S2
ReducedVentricular
Filling
AtrialSystole
:>O
:>D

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Cardiac cycle