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comprehensive management of a cleft lip and palate patient by a pedodontist



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comprehensive management of a cleft lip and palate patient by a pedodontist

  3. 7. Heredity- defect seems to run in families Environmental factors- teratogens like rubella virus, thalidomide
  4. 8. Syndromes associated with cleft lip and palate <ul><li>Treacher Collins syndrome </li></ul><ul><li>Pierre Robbin anomaly </li></ul><ul><li>More than 300 syndromes associated </li></ul><ul><li>According to Bixier 1 % of CL±P and 8% of CP cases are syndromic </li></ul>
  5. 9. <ul><li>Inactivation or deletion of MSX1 gene </li></ul><ul><li>mutation of Interferon Regulatory Factor-6 gene(IRF6) </li></ul><ul><li>Defect in Poliovirus receptor related-1 ( PVRL1 ) gene is being responsible for syndromes associated with clefting </li></ul><ul><li>. </li></ul>
  6. 10. <ul><li>Van der Woudes syndrome </li></ul><ul><li>Oro-facio digital syndrome </li></ul><ul><li>Apert syndrome </li></ul>
  7. 11. Diagnosis
  8. 12. Parental Counseling At Birth
  9. 13. The photos of the treated patients can be used for parents counseling
  10. 14. Feeding Advise
  11. 15. <ul><li>Feeding problems often associated with cleft anomalies, make it difficult for the infant to maintain adequate nutrition. </li></ul><ul><li>These problems include insufficient suction to pull milk from the nipple, excessive air intake during feeding, choking, nasal discharge, and excessive time required to take nourishment. </li></ul>
  12. 16. Feeding by nasogastric tube
  13. 17. Feeding of cleft lip and palate patients Pigeon feeder Haberman feeder Squeeze bottle
  14. 18. Feeding Spoon Feeding teats
  15. 19. Cleft Babies Should Be Kept In Upright Position For Feeding To Make Gravity Aid In Milk Feeding Fruit drinks, baby fruit juices and squashes have an erosive potential .
  16. 20. <ul><li>The feeding obturator is a prosthetic aid that is designed to obturate the cleft and restore the seperation between the oral and nasal . </li></ul><ul><li>The obturator prevents the tongue from entering the defect and interfering with spontaneous growth of the palatal shelves </li></ul><ul><li>Provides maxillary orthopedic molding of the cleft segments ino approximation before primary alveolar cleft bone grafting </li></ul><ul><li>Reduces nasal regurgitation, </li></ul><ul><li>Also helps in the development of the jaws and speech </li></ul>OBTURATOR OBTURATORS
  17. 21. <ul><li>Method I </li></ul><ul><li>To create a preliminary impression tray, cut a piece of light-polymerizing acrylic resin to the approximate size of the hard palate. </li></ul><ul><li>Use a finger to insert it into the baby’s mouth and press the material over the hard palate and into the buccal and labial vestibules. Remove the material and light-polymerize it extraorally. </li></ul>Technique of fabrication of Obturators:
  18. 22. <ul><li>Load the tray with a thick mix of tissue conditioning material and insert it intraorally, while the baby is held face toward the floor, in order to prevent aspiration in the event of vomiting and asphyxia due to airway obstruction. </li></ul>
  19. 23. <ul><li>Paint vinyl polysiloxane adhesive over the intaglio surface, and load it with viscous vinyl polysiloxane impression material </li></ul><ul><li>Monitor the baby’s oxygen level throughout . </li></ul><ul><li>Ensure that the baby is making suckling motions, for this will create the desired border molding, and ensure the baby’s ability to perform nasal breathing. </li></ul>Definitive impression.
  20. 24. <ul><li>– the primary </li></ul>softened green stick compound is placed in the infants mouth and molded and allowed to set which will serve as the special tray. A handle is also molded at 45 0 Putty consistency addition silicone impression material <ul><li>Obtaining wash impression with </li></ul>
  21. 25. Method 3 <ul><li>A wax sheet of approximate size and shape is adapted intraorally using the thumb and index finger. </li></ul>
  22. 26. <ul><li>A stone model of the negative wax reproduction is then obtained. </li></ul><ul><li>Stone cast used to fabricate the acrylic tray. </li></ul><ul><li>A wax spacer is adapted on the stone model on which a custom acrylic tray with a handle is prepared. </li></ul>Custom acrylic tray smoothened and polished
  23. 27. <ul><li>Final Impression of the BCLP infant made with infant lying on the lap of the parent </li></ul>Final Impression of BCLP infant in fast setting putty material.
  24. 28. The Pre Maxillary orthopedics Naso Alveolar Molding
  25. 29. It is a modern presurgical orthopedic device that allows for a positive growth of alveolar ridges into a improved arch form NAM is non surgical method of reshaping alveolus, lip and nostrils before cleft lip and palate surgery, lessening the severity of cleft. It is the passive method of bringing the gum and lip together by redirecting the forces of natural growth
  26. 30. <ul><li>The modern school of presurgical orthopaedic treatment in cleft lip and plate was started by McNeil in 1950 .    He used a series of plates to actively mould the alveolar segments into the desired position. </li></ul><ul><li>Burston, an orthodontist, further developed McNeil's technique and made it popular.   </li></ul>In 1689, Hoffmann demonstrated the use of facial binding to narrow the cleft and prevent postsurgical dehiscence. 
  27. 31. <ul><li>The moulding plate is fabricated on the dental stone model. All the undercuts </li></ul><ul><li>and the cleft space are blocked with wax. The plate is made up of clear self-cure acrylic </li></ul><ul><li>The plate must be 2-3 mm in thickness to provide structural integrity and to permit adjustments during the process of molding . </li></ul>A small opening measuring 6-8 mm in diameter is made on the palatal surface of the moulding plate to provide an airway in the event that the plate drops down posteriorly.
  28. 32. <ul><li>Tray material </li></ul><ul><ul><li>To make custom trays or for relining where stability & accuracy is required(combines the accuracy of self cure and strength & dimensional stability of light cure) </li></ul></ul><ul><li>COE-SOFT </li></ul><ul><ul><li>Resilient,self cure relining material(no monomers-no burning sensation,no unpleasant taste) </li></ul></ul>Materials used <ul><ul><ul><ul><ul><li>The initial gap is measured with a caliper and ruler and recorded in the patient`s chart </li></ul></ul></ul></ul></ul>
  29. 33. <ul><li>A retention button is fabricated and positioned anteriorly at an angle of 40 0 to the plate. </li></ul><ul><li>In the unilateral cleft only one retention arm is used. The exact location of the retention arm is determined at the chair side. It is positioned so as not to interfere with bringing the cleft lips together. </li></ul><ul><li>The vertical position of the retention arm should be at the junction of the upper and lower lip. </li></ul>
  30. 34. Appliance insertion and taping <ul><li>The appliance is inserted in the same fashion as a denture by sliding one side in first and then the other. </li></ul><ul><li>The elastics are stretched as far as possible so that the entire set is tied. </li></ul><ul><li>The appliance is secured extraorally to the cheeks by surgical tapes that have orthodontic elastic bands at one end. </li></ul><ul><li>A liquid adhesive like Masitol is painted with a cotton applicator horizontally on the cheeks </li></ul><ul><ul><li>Non-soluble,non-irritating,clear </li></ul></ul><ul><li>The use of skin barrier tapes on the cheeks like DuoDerm or Tegaderm is advocated to reduce irritation on the cheeks. </li></ul>
  31. 35. <ul><li>The horizontal surgical tapes are a quarter inch in width and about 3-4 inches in length. </li></ul><ul><li>The elastic on the surgical tape is looped on the retention arm of the moulding plate and the tape is secured to the cheeks. </li></ul><ul><li>The elastics (inner diameter 0.25 inch, wall thickness heavy ) should be stretched approximately two times their resting diameter for proper activation force of about 100 grams . </li></ul>
  32. 36. <ul><li>Additional tapes may be necessary to secure the horizontal tape to the cheeks. </li></ul><ul><li>It is worn 24 hours a day and is removed only for feeding. The desired movement can usually be accomplished within 6 to 8 weeks </li></ul><ul><li>The infant may require time to adjust to feeding with the NAM appliance in the first few days. </li></ul>
  33. 37. Appliance Adjustments <ul><li>The baby is seen weekly for adjustments to the molding plate to bring the alveolar segments together . moulding plate is adjusted by removing about 1mm soft acrylic along the medial surface of distorted major segment. </li></ul><ul><li>The labial flange and palate adjacent to the cleft are areas of adjustments . </li></ul><ul><li>They are made by selectively removing the hard acrylic and adding the soft denture base material(Coe soft) to the molding plate. </li></ul><ul><li>No more than 1 mm of modification of the molding plate should be made at one visit. </li></ul><ul><li>Weekly adjustments are required for maximum effectiveness of the presurgical appliance. </li></ul><ul><li>On each visit, a anew impression is taken and poured with plaster of paris </li></ul><ul><li>The alveolar cleft is measured with a gauge and approximated by 1mm </li></ul>If the appliance is lost or not worn the cleft gap that been closed early during the moulding therapy may widen again as the infant places his or her tongue into the cleft.
  34. 38. Nostril horizontally oriented. <ul><li>Cleft lip nasal deformity is characterised by a flattened nasal alar cartilage </li></ul><ul><li>on the side of the cleft that is splayed out by the alveolar gap </li></ul>Clinical features
  35. 40. The nasal stent is delayed until the cleft of the alveolus is reduced to about 5-6 mm in width.  Incorporation of the nasal stent 
  36. 41. <ul><li>Extreme care should be taken while removing the cheek tape to avoid any irritation to the skin. Skin barrier tapes like Tegaderm TM are recommended. </li></ul><ul><li>Slight relocation of the position of the tape during treatment is also recommended to provide rest to the tissues in case they become irritated. </li></ul><ul><li>It is also recommended that an aloe vera gel be applied to the cheeks when changing tapes.  </li></ul>
  37. 42. Advantages of performing NAM <ul><li>provides a more coalescent cleft and an ideally shaped alveolar arch form. </li></ul><ul><li>It diminishes tension during primary surgery,making scar formation more diificult </li></ul><ul><li>Alignment of alveolar segment creates the foundation for good lip symmetry </li></ul><ul><li>More favourable bone formation by reducing the cleft gap </li></ul><ul><li>Allows the surgeon to definitely correct the nose, without extensive dissection </li></ul><ul><li>Diminished need for bone grafting during the mixed dentition stage, </li></ul>
  38. 44. <ul><li>To achieve non-surgical lengthening of the columella, a horizontal band of the denture material is added to join the left and right lower lobes of the nasal stent, spanning the base of the columella. </li></ul><ul><li>This band sits at the naso labial junction and defines this angle as the nasal tip continues to be lifted and projected forward. </li></ul>Non-surgical columella lengthening in bilateral cleft lip and palate
  39. 45. <ul><li>Premaxillary Retraction. </li></ul>In cases of bilateral cleft lip and palate, premaxillary segment may be positioned severely anterior to the maxillary arch if lip surgery is undertaken with the premaxilla in such an abnormal position, the chances of lip dehiscence by increased pressure at the suture lines are increased.
  40. 46. <ul><li>Segments may be deviated laterally to one side of the cleft defect. In such cases a straight extra oral force would not place the pre maxilla in the facial midline, it must be positioned before pre maxillary retraction. By the application of sequential differential force to the premaxilla with elastic straps attached to the bulb prosthesis. </li></ul>
  41. 47. <ul><li>An impression is made of the infant's premaxilla for construction of an external acrylic &quot;bulb&quot; prosthesis. </li></ul>This appliance is fitted over the protruding and laterally displaced premaxilla and anchored to the infant's head with a bonnet appliance.
  42. 48. <ul><li>The premaxillary segment are retracted in a simpler manner than with the bonnet retraction system. </li></ul>
  43. 49. LATHAM S APPLIANCE FOR PRESURGICAL REPOSITIONING OF THE PROTRUDED PREMAXILLA IN BILATERAL CLEFT LIP AND PALATE The appliance is designed so that it could be secured to the palatal segments with stainless steel pins(pinning principle as described by Georgiade in 1970
  44. 50. <ul><li>Turning the screw expands the gap between the anterior borders of the lateral segments. </li></ul><ul><li>The appliance is available commercially and individually adapted to a plaster cast with the help of an acrylic plate. </li></ul>Journal of Cranio-Maxillo-Facial Surgery 1992:20,99-110
  45. 51. <ul><li>This treatment is expensive, </li></ul><ul><li>may inhibits maxillary growth (Pruzansky.,1964) </li></ul><ul><li>Increases the incidence of dental caries (Bokhoutet al.,1996) </li></ul>Emmy M Konst et al Cleft Palate-Craniofacial Journal,Jan 2004,41(1);71-77 CONTROVERSIES OF INFANT ORTHOPAEDICS
  47. 54. Palatoplasty
  48. 55. <ul><li>As soon as the alveolar gap distance reaches a gap of 2mm or less,primary surgical repair of the nose and the lip can be carried out </li></ul><ul><li>the repair of palate between 1- 1 1/2 year of age gives the best balanced resultEarly repair leads to better speech development but severe midfacial growth retardation and dental malocclusion </li></ul><ul><li>If palatal repair is done after full growth of the maxilla, midfacial growth retardation and dental malocclusion problems will be less, but speech problem will be very severe. </li></ul>
  49. 56. Timing of cleft palate repair
  50. 57. <ul><li>surgeon must obtain tissue to bridge the cleft area. techniques involved is raising </li></ul><ul><li>mucoperiosteal flaps from the palate and relocating them medially and posteriorly, </li></ul><ul><li>leaving a denuded area of bone adjacent to the alveolar process. </li></ul>
  51. 58. DENUDED BONE The filling in of the denuded area produces scar tissue, which exerts an initial contracting force on adjacent tissues resulting in midfacial growth retardation and skeletal malocclusion hemorrhage, and hematoma formation, or contraction during healing, tends to pull the flaps away from the vault. The lowered, irregular vault impinges on the space available for the tongue and interferes with tongue posture and function. Effect of palate reconstruction on maxillary complex
  52. 59. <ul><li>The scarred palatal mucosa resists further growth to some extent, and tension on the periodontal fibers during tooth eruption causes a posterior and medial deflection of the teeth . Thus, the satisfactory relationship of the primary teeth progressively worsens by the time of full permanent dentition. </li></ul>Non cleft cleft 14 yrs 4 yrs
  53. 60. HEARING <ul><li>More middle ear disease mainly due to failure of ventilatory function of eustachian tube i.e it is short, </li></ul><ul><li>Tensor veli palatine muscle is abnormally inserted into tube, These dysfunctions causes otitis media with effusion commonly known as glue ear . Early palatine surgery improves eustachian tube functions and any hearing problem should be repaired before the child learns to speak. </li></ul>
  54. 61. <ul><li>Speech disorders are due to multi causes. </li></ul><ul><li>1. Abnormal oronasal structure </li></ul><ul><li>eg. Velopharyngeal insufficiency It occurs when velopharyngeal spincher does not close adequately,. </li></ul><ul><li>ENT problems(hearing), nasal deviation oronasal fistula etc. </li></ul><ul><li>2. Abnormal growth of oronasal structures </li></ul><ul><li>eg. Malocclusion </li></ul><ul><li>3. Neurological deficit </li></ul><ul><li>eg. Learning disorders and psychological level. </li></ul>
  55. 62. <ul><li>In hyponasality there is insufficient air in the nose during speech. </li></ul><ul><li>Hypernasal speech is the common speech defect occurs due to incomplete closure between soft palate and pharyngeal wall.due to velopharyngeal insufficiency </li></ul><ul><li>It should be corrected by pharyngoplasty and speech therapy. </li></ul>
  56. 63. <ul><li>A rehabilitative procedure employing a palatal lift prosthesis (PLP) to recover diminished speech function. </li></ul>
  57. 64. A lateral cephalogram showing A: a low-draped soft palate and a wide opening in the velopharyngeal port, and B: elevation of the soft palate by the palatal lift prosthesis.
  58. 65. Clinical Examination <ul><li>Use of small dental mirrors No.2.18mm diameter. (Busch and Co Engelskirchen, Germany.) </li></ul><ul><li>Lap to lap examination with head of the child gently lowered on to the dentist lap. </li></ul>
  59. 66. Tooth brushing <ul><li>After lip repair parents should be told to lift the lip with the aid of index finger along the labial gingiva without damaging the scar. </li></ul>
  60. 67. <ul><li>Access to the teeth in the cleft region is often difficult and a baby-sized toothbrush is still useful even at this age, especially where the upper lip is tight. </li></ul><ul><li>This can be supplemented with an interspace brush. </li></ul>
  61. 68. <ul><li>Tooth paste containing no more than 600ppm fluoride is recommended for children under 6 yrs of age. </li></ul>BDJ 2000
  62. 69. <ul><li>Current treatment protocols of cleft lip and palate patients involve the combined use of </li></ul><ul><ul><li>Orthodontic treatment </li></ul></ul><ul><ul><li>Alveolar bone grafting </li></ul></ul><ul><ul><li>Implant rehabilitation </li></ul></ul><ul><ul><li>lefort1Maxilarry advancement </li></ul></ul><ul><ul><li>osteogenisis distraction </li></ul></ul><ul><ul><li>Mandibular osteotomy after growth completion </li></ul></ul>MIXED DENTITION (6th year to 11nth year.)
  63. 70. Orthodontic treatment <ul><li>The midfacial deformities in cleft lip and palate due to limitation of growth include </li></ul><ul><li>Transverse maxillary deficiency with of crossbite </li></ul><ul><li>Midfacial retrusion </li></ul><ul><li>Reduced antero-posterior development </li></ul><ul><li>Mandibular prognathism </li></ul><ul><li>A concave soft tissue profile </li></ul>Katsuhiro Minami et al J Cleft palate craniofacial anomalies
  64. 71. <ul><li>Collapsed maxillary buccal segments bilaterally. </li></ul><ul><li>Surgical procedures of the palate result in </li></ul><ul><li>scar tissue adjacent to the alveolus which undergo contraction during healing. </li></ul>
  65. 72. <ul><li>Palatal expansion </li></ul><ul><li>Objectives of treatment </li></ul><ul><ul><li>Achievement of proper anterior and lateral overjet correction </li></ul></ul><ul><ul><li>Correction of the antero-posterior discrepancy. </li></ul></ul><ul><li>Various expansion appliances used are </li></ul><ul><li>Fan shaped maxillary expander </li></ul><ul><li>Butter fly expander </li></ul><ul><li>Rapid maxillary expander </li></ul><ul><li>Nickel titanium expander </li></ul><ul><li>Quad helix expansion appliance </li></ul><ul><li>The banded hyrax appliance, and </li></ul><ul><li>Bonded rapid palatal expander </li></ul>Quad helix appliance Rapid palatal expansion appliance
  66. 73. Expansion Screws Bonded Type Banded Type An acrylic splint with full occlusal coverage bonded to expand (0.2mm/day) for one month has shown approximately 4.2mm expansion.
  67. 74. <ul><li>Below the transition point of 94 0 F, the metal is flexible enough for bending. After insertion as the patients mouth warms wire it tends to return to its original shape. </li></ul><ul><li>The action of the appliance is a consequence of nickel titanium’s shape memory and transition temperature effects. </li></ul><ul><li>permitting the patients to mitigate the pressure , if necessary, by drinking a cold liquid. </li></ul><ul><li>. </li></ul><ul><li>uses force level b/w 230gms and 300gms. </li></ul>
  68. 75. The children should be instructed to wear the facemask a minimum of 12-14 hrs/day. Though the skeletal changes are limited, they produce marked improvements in the soft tissue profile Orthopedic expansion and protraction of maxilla in cleft palate patients-a new treatment rationale. Protraction using a Petit’s face mask orthopedically Moving the maxillary segments after expansion of the maxilla with an expander appliance, 450 grams per side attached to the canines for 1.2 years.
  69. 76. 3 months of maxillary expansion increased arch width between first deciduous molars by 8 mm and was followed by protraction using the facial mask for 6 months. Post treatment retention period was for 1 year. Changes in 3months of expansion 8 months of protraction Changes in 1 yr retention
  70. 77. <ul><li>Tindlund and coworkers reported 0.3mm and 1.1mm anterior displacement of the posterior and anterior maxilla. </li></ul><ul><li>Ishii et al showed 1.5mm anterior movement of ANS for 63 subjects treated an average of 18 months </li></ul><ul><li>Nanda reported 1.3mm of protraction for 20 patients over a 4-6 month period </li></ul><ul><li>First molars produced significantly more anterior displacement than protraction from the first premolars. </li></ul><ul><li>Can be stabilized with TPA with palatal extensions to maintain the expansion </li></ul>Bull Tokyo dent Coll Nov 2002 Vol 43; 223 - 229
  71. 78. <ul><li>Alveolar bone grafting typically done between 9 and II years of age, when the permanent lateral incisor or the canine tooth roots are approximately one-third developed </li></ul>Alveolar bone grafting
  72. 79. <ul><li>It provides bony support to adjacent teeth. Provide bony matrix for eruption of teeth in the cleft site. </li></ul><ul><li>Eliminate oronasal fistulae. </li></ul><ul><li>Elevate the alar base. </li></ul><ul><li>adequate bone for future dental implant. </li></ul>
  73. 80. Endosseous implant placement <ul><li>It is done in case of congenitally missing lateral incisor. </li></ul>
  74. 82. Length of implant <ul><li>It is reported that implants of shorter dimensions, less than 10mm in length may result in early failure and subsequent need for replacement. </li></ul><ul><li>Matsui et al placed 71 implants, 13 to 15mm in length and followed for an average for 60 months. The overall survival rate reported in the study was 99%. </li></ul>
  75. 83. <ul><li>Long term follow up study demonstrated that use of dental implants placed in the alveoli after bone grafting is an excellent treatment modality for dental rehabilitation of patients with alveolar cleft and congenitally missing teeth </li></ul>Oral surg Oral Med Oral Pathol Oral Radiol Endod 2008
  76. 84. Distraction Osteogenesis <ul><li>Distraction osteogenesis is a powerful technique that already has revolutionized pediatric oral and maxillofacial surgery by providing a means of reliably lengthening the bones of the midface and mandible Maxillary advancement between 4 and 12 mm is achieved during 3-4 weeks and a satisfactory class 1 or class 2 molar relationship can be obtained. </li></ul><ul><li>It allows changes to the vectors of growth and results in the genesis of new tissues. </li></ul>
  77. 85. ADVANTAGES OF EXTERNAL DEVICES <ul><li>Rigid and easily adjustable </li></ul><ul><li>No need for fixing screws and devices on the lateral walls of the maxilla in growing children where developing dental follicles and roots of the permanent dentition can be damaged. </li></ul><ul><li>. </li></ul>George K. B Sandor Oral Maxillofacial Surg Clin N Am 2005;17: 485-501 Osteotomy Latency Distraction Consolidation and Remodeling.
  78. 86. For class III occlusion mandibular osteotomy is done after skeletal maturity(16 -18 yrs) Preoperative and post operative orthodontic treatment is needed to achieve proper alignment, position and inclination of tooth
  79. 87. Psychological factors in cleft surgery Education and communication problems Facial appearance and teacher perception. Behavioral inhibition and lower school achievement. Speech defectiveness and self esteem. Communication disorders are more the result of psychological problems than phonological which influences the entire development of an affected child. Anxiety and depression in adults with cleft lip and palate have been reported to be twice than normal controls. Odd one out
  80. 88. Psychological aspects Existing multispeciality care is primarily aimed at physical rehabilitation, psychological issues often being neglected. Parents of children with clefts are more likely to spoil their child by being over protective.
  81. 89. Children of the lesser god?
  82. 90. This is our domain