2. 6.1 & 6.2 CHROMOSOMES AND
MEIOSIS
6.6 MEIOSIS AND GENETIC VARIATION
Mitosis
Somatic cells undergo mitosis
One diploid cell produces 2 genetically
identical, diploid cells
There are 4 stages (prophase, metaphase,
anaphase, telophase)
DNA is copied once and divided once
Mitosis is used for development, growth, and
repair
3. Meiosis
Germ cells produce gametes (sex cells) during
meiosis
One diploid cell produces 4 genetically
different haploid cells
There are 8 stages (prophase I, metaphase I,
anaphase I, telophase I, prophase II,
metaphase II, anaphase II, telophase II)
DNA is copied once and divided twice
4. Homologous Chromosomes
Half of an organism’s chromosomes come from the
mother, and half from the father. The chromosomes
pair up to form homologous chromosomes
Homologous chromosomes are two chromosomes
with the same length, general appearance, and the
same type of genes
The pairing of the genes on the homologous
chromosomes are what code for all of an organism’s
traits (see examples in section 6.4)
5. All humans have 23 total pairs of
chromosomes, for a total of 46 chromosomes.
22 of the pairs are autosomes (body
chromosomes)
1 pair is the sex chromosomes (XX= female,
XY=male)
6. Meiosis I
Same steps as mitosis, except during
Prophase I crossing over can occur(see
below),
during Metaphase I homologous chromosomes
pair up in the middle and
during Anaphase I, the sister chromatids DO
NOT separate
By the end of Meiosis I, there are 2 haploid
cells
7. Crossing Over
Homologous chromosomes exchange genes
This results in a new combination of genes
(called recombination)
Genes that are located near each other on a
chromosome are more likely to be moved (or
crossed over) together. This is called genetic
linkage (refer to page 191)
Meiosis II
This is exactly the same as mitosis
8. 6.3 MENDEL AND HEREDITY
Gregor Mendel
An Austrian monk who is known as the “father
of genetics”
He discovered that traits (genes) are inherited
from parents by working with pea plants
He made both purebred plants and crossed
plants to see what the results would be.
9. WHY PEA PLANTS?
They reproduce quickly
They can both self-pollinate(creating
purebreds) and cross-pollinate(creating a mix
of traits)
They have “either-or” traits (the traits do not
mix to make a 3rd trait, ex. The purple flowers
and white flowers don’t mix to make a pink
flower)
(refer to page 179 to see the traits and results
of Mendel’s experiment)
10. MENDEL’S CONCLUSIONS
Mendel’s Law of Segregation:
Organisms inherit two copies of each gene,
one from each parent
Organisms donate only one copy of each gene
in their gametes. Thus, the two copies of each
gene segregate, or separate, during gamete
formation (Law of Independent Assortment)
In other words, the Law of Ind. Assortment is
saying that traits are inherited separately.
11. 6.4 TRAITS, GENES, AND ALLELES
6.5 TRAITS AND PROBABILITIES
Genes
Each gene has a specific locus, or place on
the chromosome
A gene is a piece of DNA that provides a set of
instructions to make a certain protein. The
proteins then code for traits.
Each trait is represented by alleles.
12. Letters are used to represent different alleles.
There are two alleles per trait (one from
mother, one from father)
Dominant alleles are represented by capital
letters and Recessive alleles are represented
by lowercase letters
Dominant alleles will always overpower the
recessive alleles.
13. EXAMPLE: P= purple flowers
p= white flowers
PP=purple flowers (homozygous)
pp= white flowers (homozygous)
Pp= purple flowers (heterozygous)
Genotype-the alleles/genetic code (PP or Pp)
Phenotype-the physical trait (purple or white)
14. PUNNET SQUARES
Punnet squares are used to predict the outcome of
genotypes when crossing two organisms
Monohybrid cross- crosses one trait (always yields a
3:1 phenotypic ratio)
Dihybrid cross- crosses two traits (always yield
9:3:3:1 phenotypic ratio)
15. CHAPTER 7
EXTENDING MENDELIAN GENETICS
Complex Patterns of Inheritance
Incomplete Dominance—the trait is in between
the dominant and recessive
Ex. RR=red rr=white Rr=pink
Codominance—both traits are expressed at the
same time
Ex. RR=red rr=white Rr= both red and white
16. Polygenic Traits—when two or more
genes influence a trait
Ex. Human eye color(at least 3 different
genes), human skin color (4 different genes)
Environmental factors—when the
environment plays a role in gene
expression
Ex. Sea turtle eggs become female in warmer
temps and male in colder temps
17. SEX-LINKED TRAITS—TRAITS CAUSED
BY GENES LOCATED ON THE SEX
CHROMOSOMES
The X contains many genes
The Y only determines sex (male)
A male is XY, so all of the alleles on the X are
expressed in a male, even the recessive ones
A female is XX, so dominant alleles can mask
the recessive ones
Carriers—those who carry a recessive genetic
disorder, but do not express the phenotype. They
can pass on the disorder to their offspring