Bacterial Transposons

BACTERIAL TRANSPOSONS S.FEROSEKHAN FNB-41

TRANSPOSONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Discovery of transposons ,[object Object],[object Object]

Classification of Transposons into two classes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BACTERIAL TRANSPOSONS ,[object Object],[object Object],[object Object]

BACTERIAL TRANSPOSONS - TYPES ,[object Object],[object Object],[object Object],[object Object]

1.Insertion sequences ,[object Object],[object Object],[object Object],[object Object],[object Object]

cont…. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Bacterial IS element ,[object Object],[object Object],[object Object],[object Object]

Insertion sequences in E.coli 1 or more 1426 IS4 1 or more 1300 IS3 5 1327 IS2 8 768 IS1 No.of.copies/ genome Size (bp) Elements

2.Composite transposons ,[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object],[object Object],- Terminal IS can transpose by in self Ex. Tn5, Tn9, Tn10

3. Tn 3 transposon family ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object],ITR ITR resolvase transposase β -lactamase

4.Transposable phage ,[object Object],[object Object],[object Object]

Transposable phage ,[object Object],[object Object],ITR ITR Lysis genes Integration and Replication genes Protein coat genes

Transposable phage - Mu phage

Mechanism of transposition ,[object Object],[object Object],[object Object]

Mechanism of transposition ,[object Object],[object Object],[object Object],[object Object],[object Object]

2. Non-replicative (conservative) transposition ,[object Object],[object Object],[object Object],[object Object],[object Object]

Non-replicative (conservative) transposition

Evolution of Transposons ,[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object]

Transposons causing diseases ,[object Object],[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Applications ,[object Object],[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object],[object Object]

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