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Control of Breathing and Neonatal Respiratory Diseases

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Control of Breathing RESPIRATORY CENTRE (Medulla) MEDULLARY & CAROTID CHEMORECEPTORS Higher Control Centres RESPIRATORY REFLEXES DRUG EFFECTS e.g. OPIATES & CAFFEINE CRANIAL & SPINAL MOTOR NEURONES STRETCH & PROPRIOCEPTORS LUNGS & CHEST WALL INSPIRATION
Chemoreceptors ,[object Object],[object Object],[object Object],[object Object],[object Object]
Response to Hypoxia Breathing Efforts + - Time in Minutes Older Infant Fetus Preterm baby Term baby 5 mins
Respiratory Reflexes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lung Mechanics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Definitions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Compliance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Airways Resistance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Work of Breathing ,[object Object],[object Object],[object Object],[object Object]
Pressure Volume Curves (Lung hysteresis loops) PRESSURE VOLUME INSP EXP
Pressure Volume Curves (Lung hysteresis loops) PRESSURE VOLUME LOW COMPLIANCE HIGH COMPLIANCE
Pressure Volume Curves (Lung hysteresis loops) PRESSURE VOLUME LOWER RESISTANCE HIGHER RESISTANCE
Questions on Anatomy & Physiology ?
Neonatal respiratory disease Aims:- ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hyaline membrane disease Clinical:- ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
HMD - Aetiology ,[object Object],[object Object]
HMD - Treatment ,[object Object],[object Object],[object Object],[object Object]
TTN Clinical:- ,[object Object],[object Object],[object Object],[object Object],[object Object]
TTN - Aetiology ,[object Object],[object Object],[object Object]
 
TTN - treatment ,[object Object],[object Object]
Airleak Syndromes ,[object Object],[object Object],[object Object],[object Object]
Pneumothorax Clinical:- ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Pneumothorax - aetiology ,[object Object],[object Object],[object Object]
Pneumothorax - predisposing factors ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pneumothorax - prevention ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pneumothorax - Treatment ,[object Object],[object Object],[object Object],[object Object]
Pulmonary interstitial emphysema ,[object Object],[object Object],[object Object]
 
PIE - Clinical features ,[object Object],[object Object],[object Object],[object Object]
PIE - Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Persistent pulmonary hypertension of the newborn Clinical features ,[object Object],[object Object],[object Object],[object Object]
PPHN - Aetiology and predisposing factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PPHN - treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Meconium aspiration syndrome Clinical: ,[object Object],[object Object],[object Object]
 
 
MAS - Aetiology ,[object Object],[object Object],[object Object]
MAS - effects of meconium ,[object Object],[object Object],[object Object],[object Object]
MAS - Management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pulmonary haemorrhage Clinical ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Pulmonary haemorrhage -Aetiology ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pulmonary haemorrhage - Treatment ,[object Object],[object Object],[object Object],[object Object]
Chronic lung disease Clinical ,[object Object],[object Object]
CLD - Aetiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CLD - prevention ,[object Object],[object Object],[object Object],[object Object],[object Object]
CLD treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Control of Breathing and Neonatal Respiratory Diseases

  • 1. Control of Breathing RESPIRATORY CENTRE (Medulla) MEDULLARY & CAROTID CHEMORECEPTORS Higher Control Centres RESPIRATORY REFLEXES DRUG EFFECTS e.g. OPIATES & CAFFEINE CRANIAL & SPINAL MOTOR NEURONES STRETCH & PROPRIOCEPTORS LUNGS & CHEST WALL INSPIRATION
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  • 3. Response to Hypoxia Breathing Efforts + - Time in Minutes Older Infant Fetus Preterm baby Term baby 5 mins
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  • 10. Pressure Volume Curves (Lung hysteresis loops) PRESSURE VOLUME INSP EXP
  • 11. Pressure Volume Curves (Lung hysteresis loops) PRESSURE VOLUME LOW COMPLIANCE HIGH COMPLIANCE
  • 12. Pressure Volume Curves (Lung hysteresis loops) PRESSURE VOLUME LOWER RESISTANCE HIGHER RESISTANCE
  • 13. Questions on Anatomy & Physiology ?
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