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Primary Care for the Red Eye

       Alice L. Bashinsky, M.D.
      Phillip C. Hoopes, Jr, M.D.
          September 2, 2003
When in Doubt
Ophthalmology Consult
– 6-4091
– Please, Please, Please…check the vision prior to
  calling. (Call a cards consult without an EKG?)
– “Vision Intact” does not count
– CN II-XII, PERRLA…careful
– Don’t wait until it’s too late
     Gen Med Example
     Leukemia Example
Anatomy
History
Demographic data (name, DOB, sex, race, occupation)
Identity of other pertinent health care providers
Chief complaint
History of present illness
Present status of vision (patient’s perception of his/her
visual status) and ocular symptoms
Past ocular history (eye diseases, injuries, diagnoses,
treatments, surgeries, medications)
Past systemic history (PMH, all, meds, FH, soc)
Family history of ocular disease
Eight Part Eye Exam
Visual acuity
– With present correction (if available)
– Distance and/or near
– Examine each eye individually
Pupillary exam
Ocular alignment and motility
Visual field
Tonometry (intraocular pressure)
External eye and ocular adnexa
Anterior segment
Posterior segment
Tools of the Trade
Snellen acuity chart
Near acuity card
Color vision plates
Penlight or Finnhoff transilluminator
Direct ophthalmoscope
Blue filter or Wood’s lamp
Tonopen
Tetracaine or proparacaine
Fluorescein drops or strips
Small toy/pediatric fixation target
Tools of the Trade
Blepharitis
Common
Chronic inflammation of eyelids, 3 types:
– Seborrheic: with dandruff of brows/scalp
– Staphylococcal infection: styes (hordeola)
– Meibomian (lipid) gland dysfunction: chalazia
Symptoms
    Irritation/itching
–
    Burning
–
    Foreign body/gritty sensation
–
    Tearing
–
    +/- Photosensitivity
–
    Intermittent blurred vision
–
Blepharitis
Signs
    Erythema of lid margins
–
    Eyelash debris
–
    Eyelid crusting
–
    Chalazia and hordeola (styes)
–
    Eyelash loss
–
    Chronic conjunctivitis
–
Treatment
– Warm compresses, lid hygeine
– Artificial tears
– Occasional steroid/antibiotic ointment
Blepharitis
Viral Conjunctivitis
Common
“Pinkeye”
Acute adenoviral infection
Symptoms
    Watering
–
    Soreness
–
    Itching
–
    Light sensitivity
–
    Intermittent blurred vision
–
    Second eye often involved 3-7 days after first
–
Viral Conjunctivitis
Signs
    Diffuse conjunctival injection
–
    Watery or mucoid discharge
–
    Eyelid erythema/edema
–
    Follicular conjunctivitis
–
    Preauricular adenopathy
–
Treatment
    Self-limiting disease
–
    Cold compresses
–
    Artificial tears
–
    +/- Topical vasoconstrictor/antihistamine
–
    Infection control
–
Viral Conjunctivitis
Bacterial Conjunctivitis
Not common
Staphylococcus aureus, Haemophilus,
Streptococcus pneumoniae, Moraxella
N. gonorrhoeae, N. meningitidis (rare)
Symptoms
– Irritation
– Profuse discharge
– Intermittent blurred vision
Signs
– Mucopurulent exudate
– Lid erythema/edema
– Diffuse conjunctival injection
Bacterial Conjunctivitis
Workup
– Gram’s stain and conjunctival culture
Treatment
– Warm or cold compresses, artificial tears, +/- broad-
  spectrum antibiotics 4-6x/day
     Fluoroqionolone (Ocuflox, Ciloxan, Quixin)
     Polymyxin/trimethoprim (Polytrim)
     Sulfacetamide (Sulamyd, Bleph-10)
Ophthalmology referral if hyperpurulent and
hyperacute (GC can rapidly invade and perforate
cornea)
Bacterial Conjunctivitis
Chlamydial Conjunctivitis
Ocular inoculation from genital infection with
Chlamydia trachomatis
Symptoms
    Acute or subacute
–
    Irritation
–
    Tearing
–
    Photosensitivity
–
Signs
    Usually unilateral
–
    Diffuse follicular conjunctival reaction
–
    Scant mucopurulent discharge
–
    Preauricular adenopathy
–
Chlamydial Conjunctivitis
Workup
– Giemsa stain of conjunctival scraping for basophilic
  inclusion bodies
– Direct fluorescent antibody staining of conjunctival
  scrapings
Treatment
– Oral docycycline 100mg po bid x 3 weeks (or tetracycline
  or erythromycin) vs Azithromycin 1g po x 1
– Topical erythromycin ointment 2-4 x/day
– Treat sex partner
Allergic Conjunctivitis
Seasonal, history of atopic disease, airborne
allergens with type-I hypersensitivity reaction
Symptoms
– Itching
– Tearing
– Intermittent blurry vision
Signs
– Bilateral diffuse conjunctival injection
– Watery to stringy mucoid discharge
Allergic Conjunctivitis
Treatment
– Avoid allergens
– Cool compresses
– Artificial tears
– Systemic and/or topical antihistamines (Vasocon-A,
  Naphcon-A)
– Topical mast cell stabilizer (Patanol, Alomide, Crolom)
– Topical NSAID (Acular, Voltaren)
Subconjunctival Hemorrhage
Etiology
– Trauma, surgery, eye-rubbing
– Valsalva
– Anticoagulants, coagulopathies
Symptoms
– Possible mild foreign body sensation
Signs
– Blood-red, well-circumscribed area overlying sclera
Treatment
– Reassurance
– Cold compresses
– Artificial tears
Subconjunctival Hemorrhage
Corneal Abrasion
Trauma
Symptoms
    Sudden onset severe pain
–
    Foreign body sensation
–
    Blurred vision
–
    Tearing
–
    Photosensitivity
–
Signs
    Diffuse conjunctival injection
–
    Watery discharge
–
    Staining epithelial defect
–
    +/- Corneal edema/haze
–
Corneal Abrasion
Treatment
– Artificial tears
– Topical NSAID
– Topical antibiotic drop or ointment
  (erythromycin ointment qid; NOT gentamicin!)
– Ophthalmology referral if non-healing for 48
  hours, or if contact lens-associated
Corneal Abrasion
Hyphema
Hyphema
Blunt Trauma
Layered blood inside the anterior chamber
At high risk for re-bleeding and glaucoma
May have nausea, photophobia, pain
Sickle cell patients at particular risk
Treat with strict bed rest, cyclopegia, topical
steriods
Needs ophthalmologist
Contact Lens Overwear
Symptoms
– Mild to moderate blurry vision
– Tearing
– Pain
Signs
– Watery to mucoid discharge
– Diffuse or perilimbal conjunctival injection
– Clear or hazy cornea
– Variable corneal staining (punctate to epithelial defect)
Contact Lens Overwear
Treatment
– Discontinue contact lens wear
– Topical NSAID
– Topical antibiotic (NOT gentamicin!)
– Ophthalmology or optometry referral
It is NOT OK to sleep in contact lenses,
unless specified by ophthalmologist
Corneal Foreign Body
           Evert upper lids
           Tetracaine or proparacaine
           for anesthesia
           Removal
           – Irrigation
           – Cotton swab
           – 20 gauge needle at slit-lamp
              for metallic foreign body
           Follow-up with
           Ophthalmology within 24
           hours
Chemical Injuries
Use pH paper and flourescein to evaluate
Immediately irrigate, irrigate, irrigate!!!
Continue irrigation until pH = 7
May require 5-10 liters of irrigation
Erythromycin ointment qid (at least)
Alkali (Drano, etc.) worst
Testing pH
Morgan Lens Irrigation
Corneal Ulcer
History of trauma, foreign body, contact lens
wear, corneal exposure
Symptoms
– Unilateral severe pain, decreased vision, photophobia,
    tearing
Signs
– Dense corneal infiltrate (opacity) with overlying
    epithelial defect; variable corneal thinning
    Diffuse conjunctival injection
–
    Mucopurulent discharge
–
    Possible hypopyon
–
    Small, sluggish pupil
–
    Variable intraocular pressure
–
Corneal Ulcer
Workup (by ophthalmologist)
– Scrapings for Gram’s stain
– Cultures (bacterial, fungal, viral)
Treatment
– Immediate ophthalmology referral
– Topical antibiotics
Corneal Ulcer
Corneal Ulcer
Herpes Simplex Keratitis
Primary or latent HSV infection
Symptoms
– Primary: severe monocular pain, photophobia, tearing,
  blurred vision
– Latent: asymptomatic to mild pain or foreign body
  sensation, photosensitivity, blurred vision
Signs
– Primary: vesicular blepharitis, follicular conjunctivitis,
  preauricular adenopathy, staining epithelial dendrite(s)
– Latent: variable corneal involvement, from punctate
  keratitis to large geographic ulcer (staining), decreased
  corneal sensation
Herpes Simplex Keratitis
Treatment
– Urgent referral to ophthalmologist
– Possible epithelial debridement
– Topical trifluorothymidine (Viroptic) 9x/day or
    Vidarabine (Vira-A) ointment 5x/day
    Cycloplegic agent
–
    Erythromycin ointment to eyelid lesions bid
–
    Possible topical or oral steroids
–
    Oral antivirals (acyclovir, Valtrex) used often for
–
    prophylaxis in recurrent cases
Herpes Simplex Keratitis
Herpes Simplex Keratitis
Herpes Zoster Ophthalmicus
“Shingles”
Symptoms
– Monocular pain, unilateral headache, photophobia,
  decreased vision
Signs
– Vesicular skin rash in dermatome of 5th CN, obeys the
  midline, involves forehead/scalp/upper eyelid
– Hutchinson’s sign (rash in distribution of nasociliary
  branch of 1st division of CN V) predicts high risk of
  ocular involvement
– Conjunctivitis, keratopathy, scleritis, uveitis, optic
  neuritis, retinitis, choroiditis, glaucoma, cranial nerve
  palsies, postherpetic neuralgia
Herpes Zoster Ophthalmicus
Workup
– Consider immunocompromised state if less than 40yo
– Treatment
     Oral antiviral (acyclovir 800mg 5x/d, famciclovir 500mg tid,
     valacyclovir 1,000mg tid for 7-10d)
     If severe or patient very ill or immunocompromised, hospitalize
     and give acyclovir 5-10mg/kg IV q8h x 5-10d
     Erythromycin ointment to skin lesions bid
     Warm compresses to periocular skin tid
– Ophthalmology referral within 24 hours
     Possible topical steroid, cycloplegic, antibiotic ointment, IOP-
     lowering agent
Herpes Zoster Ophthalmicus
Episcleritis
75% idiopathic; young adults
Others: collagen vascular disease, rosacea, gout,
HZV, IBD, thyroid disease, atopy, syphilis
Symptoms
– Painless or acute onset of dull ache
– Normal visual acuity or mild blurring
– Recurrent episodes
Signs
– Sectoral or diffuse redness of one or both eyes
– Engorged episcleral vessels
– No discharge or corneal involvement
Episcleritis
Workup
– Phenylephrine (2.5%) test: blanching of episcleral
    vessels
Treatment
    Usually self-limited
–
    Cool compress
–
    Artificial tears
–
    Topical NSAID, vasoconstrictor
–
    Topical steroid (by Ophthalmologist only)
–
    Oral NSAID
–
Episcleritis
Scleritis
50% idiopathic
50% with systemic disease (RA, SLE, polyarteritis
nodosa, Wegener’s, relapsing polychondritis,
ankylosing spondylitis, GCA, gout, TB, HZV,
syphilis)
Symptoms
– Gradual onset, severe pain, photophobia, tearing,
  normal or mild blurry vision, recurrent
Signs
– Tender globe to palpation
– Sectoral or diffuse scleral erythema, thinning with
  bluish hue, edema, possible nodules or necrosis
– Possible corneal and intraocular inflammation
Scleritis
Workup
– 2.5% phenylephrine test: deep episcleral and scleral
  vessels do not blanch
– Scleral vessels cannot be moved with a cotton swab
Treatment
    Systemic evaluation by PCP or rheumatologist
–
    Ophthalmology referral
–
    Oral NSAID or corticosteroid
–
    Topicals usually not effective
–
    Possible cytotoxic agents
–
Scleritis
Iritis (Anterior Uveitis)
Idiopathic, traumatic, autoimmune, infectious, post-
operative, malignancy
Symptoms
– Unilateral or bilateral
– Pain, photophobia, tearing
– Normal to mildly decreased vision
Signs
    Perilimbal flush
–
    Watery discharge
–
    Possible constricted and sluggish pupil
–
    Variable intraocular pressure
–
Iritis (Anterior Uveitis)
Slit lamp exam
– Deposits on posterior surface of cornea (keratic
  precipitates)
– Inflammatory cells and protein (flare) in AC
– Adhesions of iris to surface of lens (posterior
  synechiae)
Workup
– Complete ocular history and exam
– Systemic history and exam for various associated
  conditions
Treatment by Ophthalmologist
– Topical/oral steroids
– Cycloplegic agent
Iritis (Anterior Uveitis)
Iritis (Anterior Uveitis)
Preseptal and Orbital Cellulitis
 Direct extension from focal eyelid/orbital
 infection
 Direct extension from sinus infection
 Complication of orbital trauma
 Complication of orbital or sinus surgery
 Vascular extension (bacteremia or facial
 cellulitis)
Preseptal and Orbital Cellulitis
 Both present with redness and erythematous,
 edematous, warm, tender periorbita
 Orbital cellulitis
 – Symptoms: blurred vision, diplopia, pain on attempted
     eye movement, headache
     Signs: above plus fever, conjunctival chemosis and
 –
     injection, proptosis, restricted ocular motility
     Often CT scan is only way to distinguish in a child
 –
     Requires IV antibiotics (Unasyn)
 –
     Low threshold for surgical drainage of abscess
 –
Preseptal and Orbital Cellulitis
Acute Angle Closure Glaucoma
Rare
Pupillary block
– Anatomically predisposed eyes with narrow
  anterior chamber angles (hyperopic)
– Precipitated by topical mydriatics, systemic
  anticholinergics or sympathomimetics,
  accommodation, or dim illumination
– Women > men by 3-4x
– Peak age 55-70 years
Acute Angle Closure Glaucoma
Symptoms
    Unilateral blurred vision
–
    Halos around lights (monocular)
–
    Intense pain and photophobia, frontal headache
–
    Vasovagal symptoms (diaphoresis, N/V)
–
Signs
    Fixed, middilated pupil
–
    Diffuse conjunctival injection
–
    Corneal edema with blurring of light reflex
–
    Shallow anterior chamber bilaterally
–
    Markedly elevated IOP, often 60-80mmHg (“rock
–
    hard”)
Acute Angle Closure Glaucoma
Treatment
– Emergent referral to Ophthalmology
– For vision of hand motion or worse
     All topical glaucoma agents, if not contraindicated
     IV Diamox
     IV osmotics (mannitol)
– For IOP<50 and less severe loss of vision
     Topical glaucoma agents
     Topical steroids
– Once IOP decreased significantly and angle is open,
  definitive treatment is laser (or surgical) peripheral
  iridotomy to both eyes
Acute Angle Closure Glaucoma
Acute Angle Closure Glaucoma

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RED EYE

  • 1. Primary Care for the Red Eye Alice L. Bashinsky, M.D. Phillip C. Hoopes, Jr, M.D. September 2, 2003
  • 2. When in Doubt Ophthalmology Consult – 6-4091 – Please, Please, Please…check the vision prior to calling. (Call a cards consult without an EKG?) – “Vision Intact” does not count – CN II-XII, PERRLA…careful – Don’t wait until it’s too late Gen Med Example Leukemia Example
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  • 7. History Demographic data (name, DOB, sex, race, occupation) Identity of other pertinent health care providers Chief complaint History of present illness Present status of vision (patient’s perception of his/her visual status) and ocular symptoms Past ocular history (eye diseases, injuries, diagnoses, treatments, surgeries, medications) Past systemic history (PMH, all, meds, FH, soc) Family history of ocular disease
  • 8. Eight Part Eye Exam Visual acuity – With present correction (if available) – Distance and/or near – Examine each eye individually Pupillary exam Ocular alignment and motility Visual field Tonometry (intraocular pressure) External eye and ocular adnexa Anterior segment Posterior segment
  • 9. Tools of the Trade Snellen acuity chart Near acuity card Color vision plates Penlight or Finnhoff transilluminator Direct ophthalmoscope Blue filter or Wood’s lamp Tonopen Tetracaine or proparacaine Fluorescein drops or strips Small toy/pediatric fixation target
  • 10. Tools of the Trade
  • 11. Blepharitis Common Chronic inflammation of eyelids, 3 types: – Seborrheic: with dandruff of brows/scalp – Staphylococcal infection: styes (hordeola) – Meibomian (lipid) gland dysfunction: chalazia Symptoms Irritation/itching – Burning – Foreign body/gritty sensation – Tearing – +/- Photosensitivity – Intermittent blurred vision –
  • 12. Blepharitis Signs Erythema of lid margins – Eyelash debris – Eyelid crusting – Chalazia and hordeola (styes) – Eyelash loss – Chronic conjunctivitis – Treatment – Warm compresses, lid hygeine – Artificial tears – Occasional steroid/antibiotic ointment
  • 14. Viral Conjunctivitis Common “Pinkeye” Acute adenoviral infection Symptoms Watering – Soreness – Itching – Light sensitivity – Intermittent blurred vision – Second eye often involved 3-7 days after first –
  • 15. Viral Conjunctivitis Signs Diffuse conjunctival injection – Watery or mucoid discharge – Eyelid erythema/edema – Follicular conjunctivitis – Preauricular adenopathy – Treatment Self-limiting disease – Cold compresses – Artificial tears – +/- Topical vasoconstrictor/antihistamine – Infection control –
  • 17. Bacterial Conjunctivitis Not common Staphylococcus aureus, Haemophilus, Streptococcus pneumoniae, Moraxella N. gonorrhoeae, N. meningitidis (rare) Symptoms – Irritation – Profuse discharge – Intermittent blurred vision Signs – Mucopurulent exudate – Lid erythema/edema – Diffuse conjunctival injection
  • 18. Bacterial Conjunctivitis Workup – Gram’s stain and conjunctival culture Treatment – Warm or cold compresses, artificial tears, +/- broad- spectrum antibiotics 4-6x/day Fluoroqionolone (Ocuflox, Ciloxan, Quixin) Polymyxin/trimethoprim (Polytrim) Sulfacetamide (Sulamyd, Bleph-10) Ophthalmology referral if hyperpurulent and hyperacute (GC can rapidly invade and perforate cornea)
  • 20. Chlamydial Conjunctivitis Ocular inoculation from genital infection with Chlamydia trachomatis Symptoms Acute or subacute – Irritation – Tearing – Photosensitivity – Signs Usually unilateral – Diffuse follicular conjunctival reaction – Scant mucopurulent discharge – Preauricular adenopathy –
  • 21. Chlamydial Conjunctivitis Workup – Giemsa stain of conjunctival scraping for basophilic inclusion bodies – Direct fluorescent antibody staining of conjunctival scrapings Treatment – Oral docycycline 100mg po bid x 3 weeks (or tetracycline or erythromycin) vs Azithromycin 1g po x 1 – Topical erythromycin ointment 2-4 x/day – Treat sex partner
  • 22. Allergic Conjunctivitis Seasonal, history of atopic disease, airborne allergens with type-I hypersensitivity reaction Symptoms – Itching – Tearing – Intermittent blurry vision Signs – Bilateral diffuse conjunctival injection – Watery to stringy mucoid discharge
  • 23. Allergic Conjunctivitis Treatment – Avoid allergens – Cool compresses – Artificial tears – Systemic and/or topical antihistamines (Vasocon-A, Naphcon-A) – Topical mast cell stabilizer (Patanol, Alomide, Crolom) – Topical NSAID (Acular, Voltaren)
  • 24. Subconjunctival Hemorrhage Etiology – Trauma, surgery, eye-rubbing – Valsalva – Anticoagulants, coagulopathies Symptoms – Possible mild foreign body sensation Signs – Blood-red, well-circumscribed area overlying sclera Treatment – Reassurance – Cold compresses – Artificial tears
  • 26. Corneal Abrasion Trauma Symptoms Sudden onset severe pain – Foreign body sensation – Blurred vision – Tearing – Photosensitivity – Signs Diffuse conjunctival injection – Watery discharge – Staining epithelial defect – +/- Corneal edema/haze –
  • 27. Corneal Abrasion Treatment – Artificial tears – Topical NSAID – Topical antibiotic drop or ointment (erythromycin ointment qid; NOT gentamicin!) – Ophthalmology referral if non-healing for 48 hours, or if contact lens-associated
  • 30. Hyphema Blunt Trauma Layered blood inside the anterior chamber At high risk for re-bleeding and glaucoma May have nausea, photophobia, pain Sickle cell patients at particular risk Treat with strict bed rest, cyclopegia, topical steriods Needs ophthalmologist
  • 31. Contact Lens Overwear Symptoms – Mild to moderate blurry vision – Tearing – Pain Signs – Watery to mucoid discharge – Diffuse or perilimbal conjunctival injection – Clear or hazy cornea – Variable corneal staining (punctate to epithelial defect)
  • 32. Contact Lens Overwear Treatment – Discontinue contact lens wear – Topical NSAID – Topical antibiotic (NOT gentamicin!) – Ophthalmology or optometry referral It is NOT OK to sleep in contact lenses, unless specified by ophthalmologist
  • 33. Corneal Foreign Body Evert upper lids Tetracaine or proparacaine for anesthesia Removal – Irrigation – Cotton swab – 20 gauge needle at slit-lamp for metallic foreign body Follow-up with Ophthalmology within 24 hours
  • 34. Chemical Injuries Use pH paper and flourescein to evaluate Immediately irrigate, irrigate, irrigate!!! Continue irrigation until pH = 7 May require 5-10 liters of irrigation Erythromycin ointment qid (at least) Alkali (Drano, etc.) worst
  • 37. Corneal Ulcer History of trauma, foreign body, contact lens wear, corneal exposure Symptoms – Unilateral severe pain, decreased vision, photophobia, tearing Signs – Dense corneal infiltrate (opacity) with overlying epithelial defect; variable corneal thinning Diffuse conjunctival injection – Mucopurulent discharge – Possible hypopyon – Small, sluggish pupil – Variable intraocular pressure –
  • 38. Corneal Ulcer Workup (by ophthalmologist) – Scrapings for Gram’s stain – Cultures (bacterial, fungal, viral) Treatment – Immediate ophthalmology referral – Topical antibiotics
  • 41. Herpes Simplex Keratitis Primary or latent HSV infection Symptoms – Primary: severe monocular pain, photophobia, tearing, blurred vision – Latent: asymptomatic to mild pain or foreign body sensation, photosensitivity, blurred vision Signs – Primary: vesicular blepharitis, follicular conjunctivitis, preauricular adenopathy, staining epithelial dendrite(s) – Latent: variable corneal involvement, from punctate keratitis to large geographic ulcer (staining), decreased corneal sensation
  • 42. Herpes Simplex Keratitis Treatment – Urgent referral to ophthalmologist – Possible epithelial debridement – Topical trifluorothymidine (Viroptic) 9x/day or Vidarabine (Vira-A) ointment 5x/day Cycloplegic agent – Erythromycin ointment to eyelid lesions bid – Possible topical or oral steroids – Oral antivirals (acyclovir, Valtrex) used often for – prophylaxis in recurrent cases
  • 45. Herpes Zoster Ophthalmicus “Shingles” Symptoms – Monocular pain, unilateral headache, photophobia, decreased vision Signs – Vesicular skin rash in dermatome of 5th CN, obeys the midline, involves forehead/scalp/upper eyelid – Hutchinson’s sign (rash in distribution of nasociliary branch of 1st division of CN V) predicts high risk of ocular involvement – Conjunctivitis, keratopathy, scleritis, uveitis, optic neuritis, retinitis, choroiditis, glaucoma, cranial nerve palsies, postherpetic neuralgia
  • 46. Herpes Zoster Ophthalmicus Workup – Consider immunocompromised state if less than 40yo – Treatment Oral antiviral (acyclovir 800mg 5x/d, famciclovir 500mg tid, valacyclovir 1,000mg tid for 7-10d) If severe or patient very ill or immunocompromised, hospitalize and give acyclovir 5-10mg/kg IV q8h x 5-10d Erythromycin ointment to skin lesions bid Warm compresses to periocular skin tid – Ophthalmology referral within 24 hours Possible topical steroid, cycloplegic, antibiotic ointment, IOP- lowering agent
  • 48. Episcleritis 75% idiopathic; young adults Others: collagen vascular disease, rosacea, gout, HZV, IBD, thyroid disease, atopy, syphilis Symptoms – Painless or acute onset of dull ache – Normal visual acuity or mild blurring – Recurrent episodes Signs – Sectoral or diffuse redness of one or both eyes – Engorged episcleral vessels – No discharge or corneal involvement
  • 49. Episcleritis Workup – Phenylephrine (2.5%) test: blanching of episcleral vessels Treatment Usually self-limited – Cool compress – Artificial tears – Topical NSAID, vasoconstrictor – Topical steroid (by Ophthalmologist only) – Oral NSAID –
  • 51. Scleritis 50% idiopathic 50% with systemic disease (RA, SLE, polyarteritis nodosa, Wegener’s, relapsing polychondritis, ankylosing spondylitis, GCA, gout, TB, HZV, syphilis) Symptoms – Gradual onset, severe pain, photophobia, tearing, normal or mild blurry vision, recurrent Signs – Tender globe to palpation – Sectoral or diffuse scleral erythema, thinning with bluish hue, edema, possible nodules or necrosis – Possible corneal and intraocular inflammation
  • 52. Scleritis Workup – 2.5% phenylephrine test: deep episcleral and scleral vessels do not blanch – Scleral vessels cannot be moved with a cotton swab Treatment Systemic evaluation by PCP or rheumatologist – Ophthalmology referral – Oral NSAID or corticosteroid – Topicals usually not effective – Possible cytotoxic agents –
  • 54. Iritis (Anterior Uveitis) Idiopathic, traumatic, autoimmune, infectious, post- operative, malignancy Symptoms – Unilateral or bilateral – Pain, photophobia, tearing – Normal to mildly decreased vision Signs Perilimbal flush – Watery discharge – Possible constricted and sluggish pupil – Variable intraocular pressure –
  • 55. Iritis (Anterior Uveitis) Slit lamp exam – Deposits on posterior surface of cornea (keratic precipitates) – Inflammatory cells and protein (flare) in AC – Adhesions of iris to surface of lens (posterior synechiae) Workup – Complete ocular history and exam – Systemic history and exam for various associated conditions Treatment by Ophthalmologist – Topical/oral steroids – Cycloplegic agent
  • 58. Preseptal and Orbital Cellulitis Direct extension from focal eyelid/orbital infection Direct extension from sinus infection Complication of orbital trauma Complication of orbital or sinus surgery Vascular extension (bacteremia or facial cellulitis)
  • 59. Preseptal and Orbital Cellulitis Both present with redness and erythematous, edematous, warm, tender periorbita Orbital cellulitis – Symptoms: blurred vision, diplopia, pain on attempted eye movement, headache Signs: above plus fever, conjunctival chemosis and – injection, proptosis, restricted ocular motility Often CT scan is only way to distinguish in a child – Requires IV antibiotics (Unasyn) – Low threshold for surgical drainage of abscess –
  • 60. Preseptal and Orbital Cellulitis
  • 61. Acute Angle Closure Glaucoma Rare Pupillary block – Anatomically predisposed eyes with narrow anterior chamber angles (hyperopic) – Precipitated by topical mydriatics, systemic anticholinergics or sympathomimetics, accommodation, or dim illumination – Women > men by 3-4x – Peak age 55-70 years
  • 62. Acute Angle Closure Glaucoma Symptoms Unilateral blurred vision – Halos around lights (monocular) – Intense pain and photophobia, frontal headache – Vasovagal symptoms (diaphoresis, N/V) – Signs Fixed, middilated pupil – Diffuse conjunctival injection – Corneal edema with blurring of light reflex – Shallow anterior chamber bilaterally – Markedly elevated IOP, often 60-80mmHg (“rock – hard”)
  • 63. Acute Angle Closure Glaucoma Treatment – Emergent referral to Ophthalmology – For vision of hand motion or worse All topical glaucoma agents, if not contraindicated IV Diamox IV osmotics (mannitol) – For IOP<50 and less severe loss of vision Topical glaucoma agents Topical steroids – Once IOP decreased significantly and angle is open, definitive treatment is laser (or surgical) peripheral iridotomy to both eyes