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การหายใจระดับเซลล์
1.
cellular respiration
2.
(Cellular respiration)
ATP
3.
ATP (Adenosine triphosphate)
4.
Pi
ATP Pi ATP
5.
ATP
6.
ATP
ATP phosphorelation
7.
H2O
kcal/mole Hydrolysis
8.
– –
9.
Inner Matrix Outer Membrance
Inner Membrance - – , ,
10.
11.
1.
(glycolysis) Acetyl_ CoA) (Krebs cycle)
12.
• •
(Emden) (Meyerhof) (parnas) • EMP pathway EMP
13.
•
C H O 6O ---> 6CO 6H O
14.
15.
16.
•
(pyruvic acid) (pyruvate) 2C3H4O3 •
17.
18.
mitochondria pyruvate
mitochondria Net: 2 Pyruvate 2 Acetyl CoA 2NADH 2C2O
19.
Krebs cycle mitochondria matrix
20.
2 Krebs cycle
/ 1 Glucose 2 Acetyl CoA 4CO2 + 6NADH2 e- transport chain +2 FADH2 + 2 ATP (substrate level phosphorylation)
21.
The pathway of electron
transport ETC electron carrier molecules e-) inner mitochondrial membrane e- e- H+ intermembrane
22.
O2
e- H+ H2O ½ O2 + 2e- + 2H+ H20 ETC ATP H+ gradient mitochondria phosphorylation
23.
Review: how each
molecules of glucose yields many ATP molecules during cellular respiration
24.
C acetyl Co.A
O2 PGAL O2 O2 O2
25.
26.
•
-oxidation • n C
27.
• beta-oxidation
beta • n C • beta -oxidation n 2-1 • beta -oxidation 5 ATP • fatty acylCoA n2 kreb cycle • kreb cycle 1 12 ATP • 1 ATP • ATP 1
28.
•
C 16 ATP • ATP n 2-1 5+ n 2 12 - 1 • ATP 16/2-1 5+ 16/2 12 – 1 • ATP 7 5+ 8 12 – 1 • ATP 35+96 – 1 • ATP 131- 1 • ATP 130
29.
•
-NH2 NH3 • urea • uric acid
30.
(NH )
pyruvic acid acetyl co.A α-ketoglutaric acid
31.
20
32.
33.
Fermentation
(Backup ATP production) Glycolysis Pyruvate Lactate (animal) CO2 + alcohol (yeast) product enzyme
34.
fermentation ATP NADH fermantation NAD+ glycolysis
35.
Alcohol fermentation (yeast)
36.
Lactic acid fermentation
(animal cell)
37.
Pyruvate as a
key junction in catabolism Glycolysis pyruvate fermentation aerobic cellular respiration O2
38.
fermantation ATP muscle cell fermentation fermentation ATP lactate muscle cell O2 lactate pyruvate glucose anaerobic alcohol alcohol fermentation
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