The document proposes enviropreneurs as a model for implementing green chemistry. Enviropreneurs are entrepreneurs focused on environmental sustainability. They view the environment as an asset, not a problem, and aim to make profits while benefiting the environment. Newreka is presented as an example enviropreneur company that has developed green chemistry solutions to reduce waste and improve yields for pharmaceutical and other industrial clients. Their methods include recycling of aqueous and solvent streams to decrease fresh water usage and waste generation.

1. ENVIROPRENEURS: A Model for implementing Green Chemistry Nitesh H. Mehta Founder Director Newreka Green Synth Technologies Pvt. Ltd. Mumbai, India [email_address]

6. Founders Team of Technocrats from IIT Bombay passionate about Nature Foundation Principles of Green Chemistry, Green Engineering & Enviropreneurship Knowledge Base & Over 40,000 experiments conducted by Experience a dedicated team of 50 Chemists & Chemical Engineers. Service Customized & Sustainable Solutions to reduce E-FACTOR * * E-FACTOR = kgs waste generated per kg product Newreka as “Enviropreneur”

8. Average Composition of Reaction Mass Solvent & Water contribute more than 90% of the Reaction Mass Source Data: ACS GCI Pharmaceutical Roundtable benchmarking exercise 2007 Average composition of Effluents will be similar. Recycle of Water & Solvent can take care of 90% of problem.

9. “ Prevent Waste: Design chemical syntheses to prevent waste, leaving no waste to treat or clean up” 1 st Principle of Green Chemistry

10. DRUG : Anti – Retroviral Drug CUSTOMER : A fast growing Indian Pharma Company CONVENTIONAL SYNTHETIC CHEMISTRY PROCESS E-Factor 32 38 28 4 Effluent 1920 TPA 2280 TPA 1680 TPA 240 TPA (for 60TPA plant) GREEN CHEMISTRY SOLUTION BY NEWREKA E-Factor 6 6 1 4 Effluent 360 TPA 360 TPA 60 TPA 240 TPA Case Study: Reducing E-Factor & Improving Yield Stage III Chlorination Stage IV Reduction Stage V Stage II Nitration Stage I Diazo. & Hydrolysis Stage VI Stage II Nitration Stage III Chlorination Stage IV Reduction Stage I Diazo & Hydrolysis Stage VI Stage V

15. Case Study: Reducing E-Factor & Improving Yield

16. E - Factor for Manufacturing Sectors Source: R A Sheldon E - Factor = Total mass of λ materials required to produce 1kg product (mass intensity) – 1 fresh Sector E - Factor Product Tonnage Oil Refining ≤ 0.1 10 6 - 10 8 Bulk Chemicals 1 – 5 10 4 – 10 6 Fine Chemicals 5 – 50+ 10 2 – 10 4 Pharmaceuticals 25 – 100+ 10 - 10 3

18. Universities Industries Common Man & Society Govt. Bodies & Financial Institutions Enviropreneurs IP & Knowledge Empowerment & Support Selling Ideas & Scale-up Sustainable Solutions Investment on R&D & Value for Solution Investments & Incentives Good ROI Employment & Healthy Living Enviropreneurs : Model for implementing Green Chemistry

19. Thank You & Wish all of You a “ Greener Future” from Team Newreka