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INDIAN DENTAL ACADEMY
Leader in continuing dental education
www.indiandentalacademy.com
www.indiandentalacademy.com
NERVE INJURIES
 
NERVE: Nerves are solid white cords
made up of bundles of axons
• Each nerve fiber is known as an
axon
• Each axon is bound by fibrous
tissue into small bundles
 
The nerve trunk is composed of 4
connective tissue sheaths from outside
inwards are:
www.indiandentalacademy.com
 
1.Mesoneurium: Suspends nerve within soft tissue
and
provides segmental blood supply
to it.
2.Epineurium: Protects nerve from mechanical
stress
3.Perineurium
4.Endoneurium
• Group of nerve fibers- FASCICULI
• Each FASCICULI is surrounded by
PERINEURIUM
• Group of FASCICULI forms a NERVE TRUNKwww.indiandentalacademy.com
Etiology of Nerve injuries:
a. LOCAL CAUSES
• Facial bone fractures.
• Treatment of oral pathological conduction.
• Maxillofical reconstructive surgery.
• Removal of impacted lower third molar.
b. CENTRAL DISEASES
- Syringomyelia
- Multiple Sclerosis
- Bulbar Paralysis
www.indiandentalacademy.com
Classification of Injuries:
In 1943 SEDDON introduced a classification of
nerve injury based on three types of nerve fiber
injury.
1. Physiologic Disruption
NEUROPRAXIA,
2. Axonal disruption AXONOTEMESIS,
3. Division of the nerve
NEURONOTEMESIS.
www.indiandentalacademy.com
Neuropraxia:
1. Least severe form of peripheral nerve injury,
2. Result of contusion of the nerve ( continuity of
epineurial sheath and axons maintained.
3. Blunt trauma, traction stretching of nerve,
inflammation or local ischemia
4. Full recovery of the nerve function within few
days or weeks.
www.indiandentalacademy.com
Axonotmesis:
Blunt trauma, nerve crushing, extreme traction of
nerve.
• Afferent fibers degenerate but nerve trunk
intact,
no disruption of endo/peri/Epineurium
• Recovery is good but incomplete (2, 4-
12month)
www.indiandentalacademy.com
Tinnel’s sign:
Painful, electric shock like sensation elicited
by tapping directly over the cutaneous
distribution of injured nerve
www.indiandentalacademy.com
Neurotmesis:
Severe disruption of connective tissue
component of nerve trunk.
( Loss of nerve continuity)
Prognosis for recovery poor
Sensory recovery is not expected when nerve
in soft tissue, but if within canal minimal
recovery expected
  www.indiandentalacademy.com
SUNDERLAND (based on degree of tissue injury)
Five degrees based on increasing anatomic severity
of injury.
Classification Description
Grade I Loss of axonal conduction
Grade II Loss of axonal Continuity
Grade III Loss of axonal and endoneurial
continuity
Grade IV Loss of perineurial continuity with
fascicular disruption
Grade V Loss of continuity of entire nerve
trunk
www.indiandentalacademy.com
COMPARTMENT SYNDROME:
•  Local increase in pressure
(edema/venous stasis) causing decreased
oxygenation.
• Abnormal vibration and touch perception
www.indiandentalacademy.com
TESTING FOR NERVE INJURY:
1. Light touch: cotton wisp
2. Two-point discrimination: >10mm abnormal
3. Localization
4. Sharp blunt differentiation
5. Thermal stimuli: 150
c to 500
c
www.indiandentalacademy.com
BASIC PRINCIPLES OF NERVE REPAIR:
1. Decompression:
2. Neurorraphy: (Gap of 10mm only)
a. Preparation of nerve stumps
b. Approximation
c. Cooptation
e. Maintaining the cooptation
 3. Nerve Grafts:
- Sural nerve
- Greater auricular nerve
www.indiandentalacademy.com
TRIGEMINAL NEURALGIA
Synonyms:
·       Tic douloureux- spasmodic contraction of facial
muscles
·       Fother gill’s disease
·       Trifacial neuralgia
www.indiandentalacademy.com
Definition:
‘A painful unilateral affliction of the face,
characterized by brief electric shock like (lancinating)
pain limited to the distribution of one or more
divisions of the trigeminal nerve’
www.indiandentalacademy.com
PREVIOUSLY CLASSIFIED AS:
1. Classical trigeminal neuralgia or Idiopathic
trigeminal neuralgia
2. Specific trigeminal neuralgia (known etiology)
Pre- trigeminal neuralgia (PTN
www.indiandentalacademy.com
INCIDENCE:
    Female affected more than
males (3:2)
   Right > left
   Middle age and elderly
  4% Bilateral
   95% Maxilla + Mandibular nerve
involved
5% Ophthalmic nerve involved
www.indiandentalacademy.com
CLINICAL FEATURES:
“WHITE AND SWEETS CRITERIA”
1. PAIN:
 Paroxysmal (lasts from few seconds to few minutes)
 Extremely intense (stabbing/ lightening/ pricking/
knife like)
Pain free episodes/ intervals
www.indiandentalacademy.com
2. TRIGGER ZONES:
        Vermilion/ alae/ cheeks/ periorbital area
        Cutaneous in distribution
        Stimuli includes- touch/ breeze/ talk/ chew/brush/shave
3. PRE-TRIGEMINAL NEURALGIA(PTN):
      Mild, lancinating/pricking type
Months to years before chronic type of trigeminal neuralgia
4. HYPERESTHESIA/ HEPERALGESIA
On routine clinical examination
www.indiandentalacademy.com
5. ALWAYS UNILATERAL:
If bilateral, then only one side affected at a time
       Unshaven and unclean face (frozen face)
       Spontaneous remission is unusual
       Attacks do not occur during sleep(characteristic)
       Secondary radiation of pain to adjacent division
HYPOTHESIS:
1. Neural back talk theory – secondary to nerve injury
2. Deafferentation of central processes due to peripheral injury
www.indiandentalacademy.com
CLINICAL FEATURES:
      Male = female
      Middle age or late life
      Pain: lancinating pain of
oropharynx or neck, lasts for week-months
      Triggered by swallowing/ cough/ talk
      Unilateral & radiates to ear & or mouth
      Syncope is a feature
      Rarely causes xerostomia/excess salivation
      Disturbs sleep
www.indiandentalacademy.com
ETIOLOGY:
1. C-P angle tumors: Acoustic Neuroma/ Cholesteotoma/
Meningioma/ Osteoma/ Angioma
2. Anatomical variation of Petrous bone/ridge
3. Aneurysms and Adhesions
4. Multiple Sclerosis
INVESTIGATIONS:
Nerve functions- sensory and motor (trigger zones)
Diagnostic nerve blocks
Special tests for tumors and systemic diseases
www.indiandentalacademy.com
Treatment modalities:
Medical:
(A)
1. Phenytoin sodium (dilantin)
200-600mg/day in divided doses
2. Carbamazepine (tegretol/ carbital)
Initially – 100mg BID
      Increase to 200mg TID
  3. Max. Dose is 1200mg/day in divided doses
Baclofen or l-baclofen (lioresal)
10-80-mg/ day in divided doses
4. Valproic acid (depakote) 125-250 mg/day
5. Clonazepam (klonopin) 0.5 - 8mg/day
6. Pimiozide (orap) 2-12 mg/day
7. Lamotragine (lamicital) 50-100mg/day
www.indiandentalacademy.com
(B) PERCUTANEOUS injections:(2days -1-week interval)
Chemicals used: local anesthesia/ absolute alcohol/ phenol-
glycerin mixture
Injection site: peripheral nerves/trigger zones/gasserian ganglion
(C) percutaneous electro-coagulation
(D) cryosurgery (-900
to –1600
c)
(E) ratners procedure/ osseous curettage
Bone decortication+curettage+triple antibiotic pack
(chloromphenicol+tetracycline+iodoform)
www.indiandentalacademy.com
TREATMENT:
▪         Medical: - Carbamazepine/ Phenytoin/ Baclofen
▪         Local: - Cryotherapy/ Alcohol Injection
▪         Surgery: - Section GPN & Upper Rootlets Of Vagus
▪         Central: - Micro vascular Decompression
www.indiandentalacademy.com
Thank you
For more details please visit 
www.indiandentalacademy.com
www.indiandentalacademy.com

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  • 1. INDIAN DENTAL ACADEMY Leader in continuing dental education www.indiandentalacademy.com www.indiandentalacademy.com
  • 2. NERVE INJURIES   NERVE: Nerves are solid white cords made up of bundles of axons • Each nerve fiber is known as an axon • Each axon is bound by fibrous tissue into small bundles   The nerve trunk is composed of 4 connective tissue sheaths from outside inwards are: www.indiandentalacademy.com
  • 3.   1.Mesoneurium: Suspends nerve within soft tissue and provides segmental blood supply to it. 2.Epineurium: Protects nerve from mechanical stress 3.Perineurium 4.Endoneurium • Group of nerve fibers- FASCICULI • Each FASCICULI is surrounded by PERINEURIUM • Group of FASCICULI forms a NERVE TRUNKwww.indiandentalacademy.com
  • 4. Etiology of Nerve injuries: a. LOCAL CAUSES • Facial bone fractures. • Treatment of oral pathological conduction. • Maxillofical reconstructive surgery. • Removal of impacted lower third molar. b. CENTRAL DISEASES - Syringomyelia - Multiple Sclerosis - Bulbar Paralysis www.indiandentalacademy.com
  • 5. Classification of Injuries: In 1943 SEDDON introduced a classification of nerve injury based on three types of nerve fiber injury. 1. Physiologic Disruption NEUROPRAXIA, 2. Axonal disruption AXONOTEMESIS, 3. Division of the nerve NEURONOTEMESIS. www.indiandentalacademy.com
  • 6. Neuropraxia: 1. Least severe form of peripheral nerve injury, 2. Result of contusion of the nerve ( continuity of epineurial sheath and axons maintained. 3. Blunt trauma, traction stretching of nerve, inflammation or local ischemia 4. Full recovery of the nerve function within few days or weeks. www.indiandentalacademy.com
  • 7. Axonotmesis: Blunt trauma, nerve crushing, extreme traction of nerve. • Afferent fibers degenerate but nerve trunk intact, no disruption of endo/peri/Epineurium • Recovery is good but incomplete (2, 4- 12month) www.indiandentalacademy.com
  • 8. Tinnel’s sign: Painful, electric shock like sensation elicited by tapping directly over the cutaneous distribution of injured nerve www.indiandentalacademy.com
  • 9. Neurotmesis: Severe disruption of connective tissue component of nerve trunk. ( Loss of nerve continuity) Prognosis for recovery poor Sensory recovery is not expected when nerve in soft tissue, but if within canal minimal recovery expected   www.indiandentalacademy.com
  • 10. SUNDERLAND (based on degree of tissue injury) Five degrees based on increasing anatomic severity of injury. Classification Description Grade I Loss of axonal conduction Grade II Loss of axonal Continuity Grade III Loss of axonal and endoneurial continuity Grade IV Loss of perineurial continuity with fascicular disruption Grade V Loss of continuity of entire nerve trunk www.indiandentalacademy.com
  • 11. COMPARTMENT SYNDROME: •  Local increase in pressure (edema/venous stasis) causing decreased oxygenation. • Abnormal vibration and touch perception www.indiandentalacademy.com
  • 12. TESTING FOR NERVE INJURY: 1. Light touch: cotton wisp 2. Two-point discrimination: >10mm abnormal 3. Localization 4. Sharp blunt differentiation 5. Thermal stimuli: 150 c to 500 c www.indiandentalacademy.com
  • 13. BASIC PRINCIPLES OF NERVE REPAIR: 1. Decompression: 2. Neurorraphy: (Gap of 10mm only) a. Preparation of nerve stumps b. Approximation c. Cooptation e. Maintaining the cooptation  3. Nerve Grafts: - Sural nerve - Greater auricular nerve www.indiandentalacademy.com
  • 14. TRIGEMINAL NEURALGIA Synonyms: ·       Tic douloureux- spasmodic contraction of facial muscles ·       Fother gill’s disease ·       Trifacial neuralgia www.indiandentalacademy.com
  • 15. Definition: ‘A painful unilateral affliction of the face, characterized by brief electric shock like (lancinating) pain limited to the distribution of one or more divisions of the trigeminal nerve’ www.indiandentalacademy.com
  • 16. PREVIOUSLY CLASSIFIED AS: 1. Classical trigeminal neuralgia or Idiopathic trigeminal neuralgia 2. Specific trigeminal neuralgia (known etiology) Pre- trigeminal neuralgia (PTN www.indiandentalacademy.com
  • 17. INCIDENCE:     Female affected more than males (3:2)    Right > left    Middle age and elderly   4% Bilateral    95% Maxilla + Mandibular nerve involved 5% Ophthalmic nerve involved www.indiandentalacademy.com
  • 18. CLINICAL FEATURES: “WHITE AND SWEETS CRITERIA” 1. PAIN:  Paroxysmal (lasts from few seconds to few minutes)  Extremely intense (stabbing/ lightening/ pricking/ knife like) Pain free episodes/ intervals www.indiandentalacademy.com
  • 19. 2. TRIGGER ZONES:         Vermilion/ alae/ cheeks/ periorbital area         Cutaneous in distribution         Stimuli includes- touch/ breeze/ talk/ chew/brush/shave 3. PRE-TRIGEMINAL NEURALGIA(PTN):       Mild, lancinating/pricking type Months to years before chronic type of trigeminal neuralgia 4. HYPERESTHESIA/ HEPERALGESIA On routine clinical examination www.indiandentalacademy.com
  • 20. 5. ALWAYS UNILATERAL: If bilateral, then only one side affected at a time        Unshaven and unclean face (frozen face)        Spontaneous remission is unusual        Attacks do not occur during sleep(characteristic)        Secondary radiation of pain to adjacent division HYPOTHESIS: 1. Neural back talk theory – secondary to nerve injury 2. Deafferentation of central processes due to peripheral injury www.indiandentalacademy.com
  • 21. CLINICAL FEATURES:       Male = female       Middle age or late life       Pain: lancinating pain of oropharynx or neck, lasts for week-months       Triggered by swallowing/ cough/ talk       Unilateral & radiates to ear & or mouth       Syncope is a feature       Rarely causes xerostomia/excess salivation       Disturbs sleep www.indiandentalacademy.com
  • 22. ETIOLOGY: 1. C-P angle tumors: Acoustic Neuroma/ Cholesteotoma/ Meningioma/ Osteoma/ Angioma 2. Anatomical variation of Petrous bone/ridge 3. Aneurysms and Adhesions 4. Multiple Sclerosis INVESTIGATIONS: Nerve functions- sensory and motor (trigger zones) Diagnostic nerve blocks Special tests for tumors and systemic diseases www.indiandentalacademy.com
  • 23. Treatment modalities: Medical: (A) 1. Phenytoin sodium (dilantin) 200-600mg/day in divided doses 2. Carbamazepine (tegretol/ carbital) Initially – 100mg BID       Increase to 200mg TID   3. Max. Dose is 1200mg/day in divided doses Baclofen or l-baclofen (lioresal) 10-80-mg/ day in divided doses 4. Valproic acid (depakote) 125-250 mg/day 5. Clonazepam (klonopin) 0.5 - 8mg/day 6. Pimiozide (orap) 2-12 mg/day 7. Lamotragine (lamicital) 50-100mg/day www.indiandentalacademy.com
  • 24. (B) PERCUTANEOUS injections:(2days -1-week interval) Chemicals used: local anesthesia/ absolute alcohol/ phenol- glycerin mixture Injection site: peripheral nerves/trigger zones/gasserian ganglion (C) percutaneous electro-coagulation (D) cryosurgery (-900 to –1600 c) (E) ratners procedure/ osseous curettage Bone decortication+curettage+triple antibiotic pack (chloromphenicol+tetracycline+iodoform) www.indiandentalacademy.com
  • 25. TREATMENT: ▪         Medical: - Carbamazepine/ Phenytoin/ Baclofen ▪         Local: - Cryotherapy/ Alcohol Injection ▪         Surgery: - Section GPN & Upper Rootlets Of Vagus ▪         Central: - Micro vascular Decompression www.indiandentalacademy.com