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Cerebral Ischemia overview

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josephmdphysics

Overview of the physiology of experimental cerebral ischemia research (1980-2005)

TechnologyHealth & Medicine
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Cerebral Ischemia Cellular and Molecular Mechanisms of the Injured Brain Joseph Grenier, MD, PhD Benedictine University The Neurophysiology Foundation
Definition ,[object Object]
Etiology of Stroke ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Animal Models Global Ischemia Models ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Brain Tissue In Vitro Models ,[object Object],[object Object],[object Object],[object Object]
Advantages/Disadvantages of Animal Models ,[object Object],[object Object],[object Object],[object Object],[object Object]
Excitotoxicity Model ,[object Object],[object Object]
Neurotrophin Biochemistry ,[object Object]
Free Radical Biochemistry ,[object Object],[object Object],[object Object]
Trace Elements Contributing to Excitotoxicity ,[object Object],[object Object],[object Object],[object Object],[object Object]
Apoptosis and Necrosis ,[object Object],[object Object],[object Object]
Neuron Selectivity ,[object Object],[object Object],[object Object],[object Object]
Heat-Shock Proteins ,[object Object],[object Object],[object Object]
Brain Ischemia and Hypothermia ,[object Object],[object Object]
Hypothermia - cont’d ,[object Object],[object Object],[object Object]
Hypothermia - cont’d ,[object Object],[object Object]
Hyperthermia ,[object Object],[object Object],[object Object]
Spinal Cord Ischemia ,[object Object],[object Object]
Mechanisms of Hypothermic Protection ,[object Object],[object Object],[object Object],[object Object]
Hemodynamics of Hypothermia ,[object Object],[object Object]
Acidosis Related Damage ,[object Object],[object Object],[object Object],[object Object],[object Object]
Acidosis Damage - cont’d ,[object Object],[object Object],[object Object],[object Object],[object Object]
Endothelins ,[object Object],[object Object],[object Object]
Cytokines ,[object Object],[object Object],[object Object],[object Object]
Interleukins ,[object Object],[object Object],[object Object]
Blood-Brain Barrier in Ischemia ,[object Object],[object Object],[object Object]
Blood-Brain Barriers in Ischemia cont’d ,[object Object],[object Object],[object Object]
BBB in Ischemia - cont’d ,[object Object],[object Object],[object Object],[object Object]
BBB in Ischemia ,[object Object],[object Object],[object Object]
BBB in Ischemia cont’d ,[object Object],[object Object],[object Object]
Nitric Oxide and Ischemia ,[object Object],[object Object],[object Object]
Nitric Oxide - cont’d ,[object Object],[object Object],[object Object]
Nitric Oxide Interactions ,[object Object],[object Object],[object Object],[object Object]
NO and Superoxide Dismutase ,[object Object],[object Object]
NO and SOD ,[object Object],[object Object],[object Object]
NO Formation in Neurons ,[object Object],[object Object]
Protein Kinase C and Ischemia ,[object Object],[object Object],[object Object]
Protein Kinase C cont’d ,[object Object],[object Object]
Effect of Ischemia on CaMKII ,[object Object],[object Object],[object Object]
MAP Kinase and Ischemia ,[object Object],[object Object]
MAP Kinase and Ischemia ,[object Object],[object Object],[object Object]
Neurotrophins and Cerebral Ischemia ,[object Object],[object Object],[object Object]
Experimental Therapies for Ischemia ,[object Object],[object Object],[object Object],[object Object],[object Object]
Experimental Therapies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Cerebral Ischemia overview

  • 1. Cerebral Ischemia Cellular and Molecular Mechanisms of the Injured Brain Joseph Grenier, MD, PhD Benedictine University The Neurophysiology Foundation
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