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SKIN & VD 2-2-2013 PSORIASIS Chronic inflammation with erythematous scaly plaques over the skin.ETIOLOGY Genetic Environmental – sunlight Drugs o Antimalarial (quinines) o Antipsychotic (lithium) o Beta blockers Post-streptococcal infection TraumaTYPES OF PSORIASISPSORIASIS VULGARIS Commonest type, erythematous scaly plaques. Nail signs: o Pits o Onicholysis o Sub-ungual hyperkeratosis o Nail plate dystrophy o Discolouration Scalp: discrete lesions (Differential diagnosis – seborrhic dermatitis, where there are complete scalp lesions. Mostly seen in extensor surfaces like elbow, knee etc.GUTTATE PSORIASIS Plaques are smaller, <1 cm. Mainly seen on trunk & proximal parts In children, self- limiting After Streptococcal infectionINVERSE PSORIASIS Seen on flexor regions like cubital fossa, axilla & groinERYTHRODERMIC PSORIASIS Keshava Pavan
SKIN & VD 2-2-2013 Generalised skin lesions Involves > 90% of body area.PUSTULAR PSORIASIS Multiple pustules Can be generalized or localized (palmar/ plantar)SCALP PSORIASIS Involves scalp.AUSPITZ SIGNLesion is scraped with glass slide. Following features are seen: Increased scaling Glistening membrane Punctate bleeding spots (bleeding due to trauma of tortuous, dilated capillaries) Keshava Pavan