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Celiac Disease.docx

  1. Lesson Plan on Celiac Disease Ms. K. Lavanya M.Sc (N)- CHN Associate Professor
  2. Objective Time Content Teachers Activity Students Activity A.V. Aids Evalua tion Definition: Celiac disease also known as gluten induced enteropathy, gluten sensitive enteropathy and celiac sprue. It is a disease of the proximal small intestine characterized by abnormal mucosa and permanent intolerance to gluten. Incidence: More frequent in Europeans than in Americans and is rarely reported in Asians or blacks. Previously it was 1 in 6000 individuals, recently it was 1 in 250 individuals. Etiology:  Idiopathic  Mutation of Genes  Absence of the healthy bacteria which helps in the digestion process.  Gluten- Consuming gluten triggers the abnormal immune system response that causes celiac disease
  3. Pathophysiology: Clinical Manifestations: Impaired Fat absorption  Steatorrhea (excessively large, pale, oily, frothly stools)  Exceedingly foul-smelling stools. Impaired Absorption of Nutrients  Malnutrition  Muscle wasting (especially prominent in legs & buttocks)  Anemia  Anorexia  Abdominal Distention
  4. Behavioral Changes  Irritability  Fretfulness  Uncooperativeness  Apathy Celiac Crisis  Acute, severe episodes of profuse watery diarrhea and vomiting May be precipitated by:  Infections (specially gastrointestinal)  Prolonged fluid and electrolyte depletion  Emotional disturbance For Adults:  Diarrhea  Fatigue  Weight loss  Bloating and gas  Abdominal pain  Nausea and vomiting  Constipation Diagnostic Evaluation:  HC  PE  Biopsy of the small intestine  Mucosal Inflammation  Crypt hyperplasia  Villous atrophy  Serologic test- to detect antibodies to connective tissue (endomysium & reticulin) and to gliadin.
  5.  Antigliadin, antireticulin, & antiendomysial IgG & IgA antibodies- More specific markers for active celiac disease.  Enzyme tissue transglutaminase (tTG), Management:  The diet should be gluten free  Restriction on wheat, rye, barley & oats  Correction of nutritional deficiencies with supplements including vitamins, iron, & Calories Complications:  Lactose Intolerance Bibliography:  Wong’s. (2005), Essentials of Pediatric nursing, 7th Edition, Elsevier Publications, New Delhi. Page no: 885- 886.
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