Dr. Cady presented this presentation at the World Link Medical seminar in Salt Lake City, UT on January 27 for the 2012 Medical Seminar Series - Mastering the Protocols for Optimization of Hormone Replacement Therapy, Part 1. It will be presented twice more for World Link Medical in 2012.

1. Louis B. Cady, MD – CEO & Founder – Cady Wellness Institute Adjunct Professor – University of Southern Indiana Adjunct Clinical Lecturer – Indiana University School of Medicine Department of Psychiatry Child, Adolescent, Adult & Forensic Psychiatry – Evansville, Indiana How to Transition from Traditional Allopathic Practice to a Holistic and Integrated Medical Model This presentation is © Louis B. Cady M.D. and may not be reproduced or used without permission. World Link Medical is authorized to reprint/duplicate it for 2012 syllabi. (c) 2012 Louis B. Cady, M.D. - all rights reserved

3. “ The mind, once expanded to the dimensions of larger ideas, never returns to its original size.” - Oliver Wendell Holmes

4. H - “ There are two objects of medical education: to heal the sick and to advance the science.” - Dr. Charles H. Mayo, MD “ The glory of medicine is that it is always moving forward, that there is always more to learn.” - Dr. William J. Mayo

6. Background

7. Death Optimal Health Traditional Medicine Hormone Modulation No Disease = Health Diet, Exercise Nutritional Supplementation “ Wellness [integrated] Medicine” Diagnose and Treat Disease New Drugs New Surgical Techniques Forestall and PREVENT Disease – Optimize Function

9. Health is a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity. - World Health Organization

10. American Journal of Health Promotion; November/December, 2002 19% of those surveyed were completely healthy with high levels of both physical and mental health and a low level of illness . 18.8% completely unhealthy, defined as having low levels of health with high levels of illness. Two-thirds of the adults reported some degree of mental or physical illness that kept them from being completely healthy. “ Incompletely healthy.” HEALTH continuum DEAD OPTIMAL 66% “ Incompletely healthy”

13. May 2002: 9 th Annual IFM Conference

14. The Functional Medicine component Dead Doctors Don ’t Lie - Joel Wallach, DVM, ND

22. What the feds see & their lust for “cost control” Example: salaries for Family Medicine Adapted from http://economix.blogs.nytimes.com/2009/07/15/how-much-do-doctors-in-other-countries-make/. Accessed April 3, 2010. US $1000 Slide courtesy of John Adams, MBA – CEO, Cenegenics

23. Medicare–Workers per Beneficiary http://facts.kff.org/chart.aspx?ch=383. Accessed April 3, 2010. Year Millions SOURCE: Kaiser Family Foundation based on the 2009 Annual Report of the Boards of Trustees of the Federal Hospital Insurance and Federal Supplementary Medical Insurance Trust Funds. Slide courtesy of John Adams, MBA – CEO, Cenegenics

25. http://www.ama-assn.org/amednews/2011/11/21/gvsd1121.htm

26. Healthcare Reform–Physicians Perception of Medicine Over the Next Few Years http://www.athenahealth.com/index.php?open=26. Accessed April 3, 2010. Slide courtesy of John Adams, MBA – CEO, Cenegenics

28. http://marketing-images.ubmmedica.com/Insights/2011/2011_GAP_Survey.pdf Accessed 01 21 2012 “ Although American doctors feel stressed, overworked, and uncertain about the future, they’re generally happy with their career choices and the state of their lives (???), despite practicing during one of the greatest periods of tumult in the modern history of US healthcare.” “ The results also suggest strongly that physicians wish they had more control of their careers… and time.”

32. “ The Great Crossover” – the microchip cf: Dan Sullivan www.strategiccoach.com

37. Accessed 1 21 2012

38. Current status of patients and society

47. February 26, 2009 6 a.m.

50. A change from the allopathic model?

53. “ Slumber not in the tents of your fathers. The world is advancing. Advance with it.” - Giuseppe Mazzine

55. What does integrated, holistic medicine “look like?” A quick dip in the literature

56. % U.S. Women with inadequate quantities of nutrients Arab L, Carriquiry A, Steck-Scott S, Gaudet MM. Ethnic differences in the nutrient intake adequacy of premenopausal US women: results from the Third National Health Examination Survey. J Am Diet Assoc 2003; 103:1008-14.

57. = 2 apples (fruits) & 3 - 4 vegetables – per CDC

60. % Mineral depletion from the soil during the past 100 years, by continent Source: UN Earth Summit Report 1992 North America 85% South America 76% Asia 76% Africa 74% Europe 72% Australia 55%

61. Cf: http://www.veganforum.com/forums/showthread.php?t=3532

68. “ Take homes”: Low folate is associated with elevated homocysteine, which is associated with neuronal damage.

69. “ Take homes”: If you smoke, and if your FA levels are not optimum, “homozygous” [double SNP] 5MTHFR mutated individuals are at higher risk of elevated homocysteine

70. “ Take homes” [this slide and following]: Elevated homocysteine is definitely not good for you!

72. Wang X et al. Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38MAPK-meidated increase in oxidant stress. J Mol Cell Cardiol. 2011 Dec 29. Epub. Accessed 1 21 2012. “ Hcy may increase the risk for CVD not only by causing endothelial dysfunction , but also by directly exerting detrimental effects on cardiomyocytes. ”

74. The Baby Boomers & Their Expectations The first time the entire Baby Boom generation is impacting a single market ALL at the same time!

76. Let’s look at the logic. How would you take care of a classic? “ Chronic diseases affect at least 125 million Americans & cost more than $500 billion last year.” Centers for DiseaseControl – Dec 2003

77. “ Age management” “Conventional practice” There are fuel additives we can use to keep our cars burning cleaner and preserve engines. No fuel additives should be used. They are unnatural. Gas is all that is required. We should use optimal quality of gas. Cheap gas causes “pinging” which is hard on the engine. The quality of the gas is irrelevant. Anything that the motor will burn is adequate. We should take our car in for preventive maintenance before anything breaks. Preventive maintenance? This is silly! Wait until something breaks, then have the car towed in so the mechanic can really tell what is wrong.

78. Modern Medicine ’s Paradigm: Two Standard Deviations – “if you are not sick, then you must be well.” “ NORMAL” OPTIMAL? OPTIMAL

82. Quick examples of powering through objections and overwhelming with literature Note – don’t get bogged down. Get the idea of HOW TO PRESENT the data.

83. A Scientific (& FUN!!!) Review of Vitamin Supplementation & Essential Nutrients Louis B. Cady, MD – CEO & Founder – Cady Wellness Institute Adjunct Professor – University of Southern Indiana Adjunct Clinical Lecturer – Indiana University School of Medicine Department of Psychiatry Child, Adolescent, Adult & Forensic Psychiatry – Evansville, Indiana Presented 2 27 2010 – Oliver Headache and Pain Clinic CME seminar – Evansville, IN

84. Trends in Pharmacological Sciences (2008) Jul; 29(7):351. Epub 2008 Jun 4

86. Zoned, Stoned and Blown: The Emotional Tsunami of Psychiatric Disorders Coupled with Pain Disorders & Chemical Dependency Louis B. Cady, MD – CEO & Founder – Cady Wellness Institute Adjunct Professor – University of Southern Indiana Adjunct Clinical Lecturer – Indiana University School of Medicine Department of Psychiatry Child, Adolescent, Adult & Forensic Psychiatry – Evansville, Indiana Also Presented 2 27 2010 – Oliver Headache and Pain Clinic CME seminar – Evansville, IN

88. Pharmacotherapy Significantly Reduces Substance Abuse in Adults with ADHD Biederman J, et al. Pediatrics. 1999;104:e20-e25. 40 30 20 10 0 % of study population Unmedicated ADHD Medicated ADHD Control 32 12 10 P <0.001 (N=56) (N=19) (N=137) 3-fold!

89. Business philosophy citations follow … END EXAMPLES…

92. Evansville Courier & Press : May 29, 2006 References: www.pharmanexmd.com ; www.slideshare.net/lcadymd ; Dr. Oz show on YouTube: http://www.youtube.com/watch?v=rX4oxxGWi_8

94. Jay Abraham References (recommended) www.amazon.com

100. Perhaps the ability not only to acquire the confidence of the patient, but to deserve it, to see what the patient desires and needs, comes through the sixth sense we call intuition, which in turn comes from wide experience and deep sympathy for and devotion to the patient , giving to the possessor remarkable ability to achieve results. ...William J. Mayo, 1935

102. Contact information: Louis B. Cady, M.D. www.cadywellness.com www.indianaTMS-cadywellness.com Office: 812-429-0772 E-mail: [email_address] 4727 Rosebud Lane – Suite F Interstate Office Park Newburgh, IN 47630 (USA)