important of candida &disease cause by candida

1. CANDIDA
Presented by:
Himangshu Sarma
B.Pharm,3rd semester
Department of Pharmaceutical Sciences
Dibrugarh University
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2. Contains:
 Introduction
 Species
 Characteristics
 Reproduction
 Importance of Candida
 Pathogenicity
 Factor increases the risk of candida infection
 Common diseases
 Prevention
 Bibliography 2

3. Introduction:
Candida are ubiquitous fungi organisms &
genus of yeasts.
It is a normal part of ordinary flora of skin,
mouth, vagina & stool.
Also found in environment on leaves,
flowers & water etc.
It is a pathogen.
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4. Species:-
 Candida includes about 154 species.
 Name of some species are –
Candida albicans
Candida parpsilosis
Candida globrata
Candida tropicalis
Candidi antarctica
Candida atlantica
Candida atmospherica
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5. Characteristics:
 Candida are –
-Thin walled
-Unicellular
-4-5µ size
-Grow rapidly & matured in 3 days.
 Colony may be large, round ,white or cream, pasty,
smooth, dry, wrinkled & dull depend upon the
species.
 Yeasty odor on agar plate at room temperature.
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7. Importance of candida:-
1.Candida anterctica is source of industrially
import lipases.
2.Candida albicans has been used in
combination with carbon nano tubes to
produce stable electrically conductive bio
nano composite tissue material that has been
used as temperature sensing elements.
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8. Reproduction:-
Candida are reproduced via budding.
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9. Pathogenicity:-
Candida attacks the mucous membrane of
oral cavity, GIT, vagina and various other
epithelium, nervous system and lymphatic
system.
It produces toxins such as canditoxin &
ethanol interferes with our biochemical
processes.
Acidic proteases &other metabolites disrupt
energy production cycle causes fatigue.
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10. DISEASES OF CANDIDA
1.Candidiasis
2. Candidaemia
3. Candidosis
4. Endocarditis
5.Meningitis 10

11. Many other illness related to candida are
include :
1. Acne
2. Sinusitis
3. Bronchitis
4. UTI infection
5. Ear infection
6. Chronic fatigue syndrome
7. Depression
8. Athelet’s foot
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12. Factors Increase The Risk Of
Candida Infection
 Repeated or prolong used of antibiotics or
steroids.
 Chronic stress.
 Consumption of alcohol.
 Oral contraceptive use.
 Diabetes.
 Hyperthyroidism.
 Diet contain high amount of simple sugar.
 In immune suppressive patient. 12

13. Oropharyngeal Candidiasis
Intestinal Candidiasis
Vulvovaginal candidiasis
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1.Candidiasis
 Candidiasis is may be categories
as follows-
 Candidiasis is mainly caused by candida
albicans.

14. a) Oropharyngeal Candidiasis:
 Candida infection in mouth or oral cavity.
Symptoms are:
Whitish film on-
-Plate
-Tongue
-Inside the cheeks
Or red lesions.
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15. b. Intestinal candidiasis:
 Candida infection occurs in mucosal layer of
GIT.
 It is also called yeast syndrome.
Symptoms are:
 General: Chronic fatigue or malaise
 GI track: thrush, bloating, gas, rectal itching,
alternative diarrhea and constipation.
 Fever, chills
 A drunken like stage without presence of
alcohol. 15

16. Treatments:
1. Diet Control :
 Dietary modification are usually implemented
for 2-4weeks to assess the respond.
 Following foods are restricted-
o Carbohydrate containing foods
o Fruits & juices
o Milk& milk product e.g.-cheese
o Mushroom
o Sweeteners e.g.-all sugars
o All vinegars& preserved foods
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17. 2.Taking bacteria:
-Such as Lactobacillus &Bifid bacteria are
ingested, rebalance the microbial flora.
3.Use of antifungal drugs :
Such as-Fluconazole
-Itraconazole
-Amphoterericine B
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18. c. Vulvovaginal candidiasis:
 Its is a mucosal infection in urogenital track
caused by candida species in women
reproductive age.
Primarily caused by candida albicans.
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SYMPTOMS:
 Itching
 Burning
 Abnormal vaginal discharge
 Dyspareunia

19. 2.Candidaemia:
Candida infection of the blood stream is called
candidaemia.
SYMPTOMS INCLUDES:
 Fever, Chills
 Skin rush
 Generalized weakness
 Muscles aches
 Headaches
 Abdominal pain
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20. PREVENTIONS :
 Infected person should adjust their diet and avoid
food which have the risk to growth of fungi.
 Eating ergot containing lactobacillus acidophilus
helps in control of candida.
 Consuming raw vegetable.
 Clothing is important factor in prevention of
candidiasis.
 Improving personal hygiene.
 Most of all educating oneself on the infection at
hand is the best away to prevent disease. 20

21. Bibliography:
Intestinal candidiasis in Applying functional
Medicine in clinical practice published by
Functional Medicine Research Center.
Candidaemia in American Journal crit care
Medical,Volume-185,Pageno.3-5,2012
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22. THANK YOU
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