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RESOURCES FOR CLINICAL 
REASONING EXERCISE 
KSOM Psychiatry 
Clerkship, 2014-2015 
Lynn Kysh, MLIS 
Information Services 
Librarian
LEARNING OBJECTIVES 
Formulate a clinical research question from clerkship 
experience 
Identify databases relevant to psychiatry and conduct 
an effective search 
Apply basic criteria to appraise evidence 
Retrieve available resources for more information on 
citation styles, search strategies, etc.
MEDICAL 
STUDENTS 
YEARS 3-4 
PORTAL 
Available on the 
Norris Medical 
Library Homepage 
usc.edu/nml 
norris.usc.libguides. 
com/medyrs3-4
REFRESHER: QUESTION TYPES 
What is the disorder? 
What causes it? 
How does it present? 
How can it be prevented? 
What are treatment options? 
Background Questions 
Foreground 
Questions 
Clinical research question 
Information for an actual 
patient 
PICO based 
Experience with condition
FORMULATE A CLINICAL RESEARCH 
QUESTION 
Scenario: 
Patient diagnosed with schizophrenia is 
being treated with an anti-psychotic drug 
(olanzapine). 
This drug is causing patient to gain 
weight. You wonder if nutrition therapy 
would be effective for weight loss.
FORMULATE A CLINICAL RESEARCH 
QUESTION: THERAPY 
Problem/Patient/Popul 
ation 
Intervention/Indicator 
Comparison/Control 
(if any) 
Outcome 
Weight gain with anti-psychotic 
olanzapine 
Nutrition therapy 
None 
Continued treatment with 
olanzapine while managing 
healthy weight
FORMULATE RESEARCH QUESTION 
How effective is nutrition therapy in reducing 
weight gain caused by olanzapine?
TYPES OF CLINICAL QUESTIONS 
How is the problem treated? 
What causes the problem? 
What is the frequency of the 
problem? 
Does this person have the 
problem? 
Who will get the problem? 
Therapy 
Etiology, Risk Factors 
Frequency 
Diagnosis 
Prognosis, Prediction
AN IDEA FOR AN ETIOLOGY 
QUESTION 
Does the recreational use of marijuana 
increase the incidence of psychosis 
among adult men?
FORMULATE A CLINICAL RESEARCH 
QUESTION: ETIOLOGY 
Problem/Patient/Popul 
ation 
Intervention/Indicator 
Comparison/Control 
(if any) 
Outcome 
Adult men 
Recreational use of marijuana 
No recreational use of marijuana 
Increased incidence of psychosis
COMMON MISTAKE IN 
FORMULATING A RESEARCH 
QUESTION 
What is the most effective treatment of 
schizophrenia? 
Who is the patient? 
Age, gender, comorbidities, etc. 
What treatments are known to be effective? 
Primary research does not answer general questions 
Consider background information tools (UpToDate, 
AccessMedicine, etc.)
Biomedical information database 
Search with automatic term mapping or Medical Subject Headings 
(MeSH)
Psychiatry-specific database 
Search with synonyms and narrower terms 
Quotes to search as phrase; * to truncate
Journal articles, meeting abstracts, dissertations, book chapters 
Search with synonyms and narrower terms 
Quotes to search phrase; * for truncation
SELECT 5 BEST ARTICLES 
1. Does this article address my research 
question (PICO)? 
2. Is this the best article for my research 
question? 
3. Does this article rely on sound research 
methodologies?
1.DOES THIS ARTICLE ADDRESS 
MY RESEARCH QUESTION 
(PICO)? 
Remember… 
Problem/Patient 
Intervention 
Comparison 
Outcome 
Source: Flahery, RJ. “A simple method for evaluating the clinical literature.” Family Practice 
Management. May 2004.
Patient 
Problem 
Interventio 
n 
Compariso 
n 
(if any) 
Outcome 
Schizophrenia or schizoaffective disorder (DSM IV) 
Men and women; 19-64 y/o 
Olanzapine for 12 weeks 
7% or more weight gain 
Associated weight gain with olanzapine 
Diet management: food diary, dietician consultation 
Exercise management: exercise diary, exercise manager 
None 
Physical exam (BMI measurement) 
Pulse rate 
Blood pressure
2. IS THIS THE BEST ARTICLE 
FOR MY RESEARCH QUESTION? 
Remember… 
Problem/Patient 
Intervention 
Comparison 
Outcome 
Add… 
Date of Publication 
Times cited (Web of 
Knowledge, PSYCinfo, Google 
Scholar) 
Publication Type 
Source: Flahery, RJ. “A simple method for evaluating the clinical literature.” Family Practice 
Management. May 2004.
TIMES CITED
PYRAMID OF PUBLICATION TYPES 
Guidelines 
Systematic 
Reviews 
Randomized 
Controlled Trials 
Cohort Studies 
Case Series, Case Reports 
Higher Quality of Information 
Fewer Articles 
Lower Quality of Information 
More Articles
Date 
Times Cited 
Publication Type 
April 2006 
69 (Web of Science) 
71 (PsycINFO) 
101 (Google Scholar) 
Randomized Control Trial (RCT)
3. DOES THIS ARTICLE RELY ON 
SOUND RESEARCH 
METHODOLOGIES? 
Critical Appraisal Charts for... 
• Systematic Reviews 
• Therapy Studies 
• Diagnosis Studies 
• Prognosis Studies 
• Harm/Etiology
Randomization 
Allocation 
Concealment 
Similar Baseline 
Characteristics 
Blinding 
To what extent? 
Follow up 
Intention to Treat 
Yes (maybe); methods not described 
Not described 
Yes 
No 
Not described 
Yes
SELECT 5 BEST ARTICLES 
1. Does this article address my research question 
(PICO)? 
YES 
2. Is this the best type of article for my research 
question? 
YES 
3. Does this article rely on sound research 
methodologies? 
MOSTLY
WHAT I AM LOOKING FOR ON THE 
ASSIGNMENT 
1 Point – Reference 5 Articles 
1 
.75 
.5 
.25 
0 
List four or five articles that relate to the research question 
and relevant PICO elements. 
List three articles that relate to the research question and 
relevant PICO elements. 
List two articles that relate to the research question and 
relevant PICO elements. 
List one article that relates to the research question and 
relevant PICO elements. 
List no articles that relate to the research question and 
relevant PICO elements.
WHAT I AM LOOKING FOR ON THE 
ASSIGNMENT 
1 Point – Provide One Article that Meets Assessment Criteria 
1 
.5 
0 
At least one article listed meets assessment 
criteria of high quality evidence (combination of 
publication type, currency, statistics, times cited, 
aApt pleraaissta ol)n. e article listed meets some 
assessment criteria ranking it as medium quality 
evidence (combination of publication type, 
cNuor raernticcyle, ss tlaisttisetdic ms,e teimt aensy c aitsesde,s aspmpernatis carli)t.eria 
ranking all articles as low quality evidence.
RESOURCES 
Citation Style LibGuide 
 Sample paper, cheat sheet, useful websites, examples, etc. 
http://norris.usc.libguides.com/citation 
Psychiatry LibGuide (Clerkship Resources) 
 Download PowerPoint, download “Simple Method for 
Evaluating Clinical Literature” article, access databases 
mentioned 
http://norris.usc.libguides.com/psychiatry
CONTACT 
Lynn Kysh, MLIS 
Information Services Librarian 
(323) 442-1124 
kysh@usc.edu
LEARNING OBJECTIVES 
Formulate a clinical research question from clerkship 
experience 
Identify databases relevant to psychiatry and conduct 
an effective search 
Apply basic criteria to appraise evidence 
Retrieve available resources for more information on 
citation styles, search strategies, etc.
QUESTIONS?
THANK YOU!

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Psychiatry clerkship

  • 1. RESOURCES FOR CLINICAL REASONING EXERCISE KSOM Psychiatry Clerkship, 2014-2015 Lynn Kysh, MLIS Information Services Librarian
  • 2. LEARNING OBJECTIVES Formulate a clinical research question from clerkship experience Identify databases relevant to psychiatry and conduct an effective search Apply basic criteria to appraise evidence Retrieve available resources for more information on citation styles, search strategies, etc.
  • 3. MEDICAL STUDENTS YEARS 3-4 PORTAL Available on the Norris Medical Library Homepage usc.edu/nml norris.usc.libguides. com/medyrs3-4
  • 4. REFRESHER: QUESTION TYPES What is the disorder? What causes it? How does it present? How can it be prevented? What are treatment options? Background Questions Foreground Questions Clinical research question Information for an actual patient PICO based Experience with condition
  • 5. FORMULATE A CLINICAL RESEARCH QUESTION Scenario: Patient diagnosed with schizophrenia is being treated with an anti-psychotic drug (olanzapine). This drug is causing patient to gain weight. You wonder if nutrition therapy would be effective for weight loss.
  • 6. FORMULATE A CLINICAL RESEARCH QUESTION: THERAPY Problem/Patient/Popul ation Intervention/Indicator Comparison/Control (if any) Outcome Weight gain with anti-psychotic olanzapine Nutrition therapy None Continued treatment with olanzapine while managing healthy weight
  • 7. FORMULATE RESEARCH QUESTION How effective is nutrition therapy in reducing weight gain caused by olanzapine?
  • 8. TYPES OF CLINICAL QUESTIONS How is the problem treated? What causes the problem? What is the frequency of the problem? Does this person have the problem? Who will get the problem? Therapy Etiology, Risk Factors Frequency Diagnosis Prognosis, Prediction
  • 9. AN IDEA FOR AN ETIOLOGY QUESTION Does the recreational use of marijuana increase the incidence of psychosis among adult men?
  • 10. FORMULATE A CLINICAL RESEARCH QUESTION: ETIOLOGY Problem/Patient/Popul ation Intervention/Indicator Comparison/Control (if any) Outcome Adult men Recreational use of marijuana No recreational use of marijuana Increased incidence of psychosis
  • 11. COMMON MISTAKE IN FORMULATING A RESEARCH QUESTION What is the most effective treatment of schizophrenia? Who is the patient? Age, gender, comorbidities, etc. What treatments are known to be effective? Primary research does not answer general questions Consider background information tools (UpToDate, AccessMedicine, etc.)
  • 12. Biomedical information database Search with automatic term mapping or Medical Subject Headings (MeSH)
  • 13. Psychiatry-specific database Search with synonyms and narrower terms Quotes to search as phrase; * to truncate
  • 14. Journal articles, meeting abstracts, dissertations, book chapters Search with synonyms and narrower terms Quotes to search phrase; * for truncation
  • 15. SELECT 5 BEST ARTICLES 1. Does this article address my research question (PICO)? 2. Is this the best article for my research question? 3. Does this article rely on sound research methodologies?
  • 16. 1.DOES THIS ARTICLE ADDRESS MY RESEARCH QUESTION (PICO)? Remember… Problem/Patient Intervention Comparison Outcome Source: Flahery, RJ. “A simple method for evaluating the clinical literature.” Family Practice Management. May 2004.
  • 17. Patient Problem Interventio n Compariso n (if any) Outcome Schizophrenia or schizoaffective disorder (DSM IV) Men and women; 19-64 y/o Olanzapine for 12 weeks 7% or more weight gain Associated weight gain with olanzapine Diet management: food diary, dietician consultation Exercise management: exercise diary, exercise manager None Physical exam (BMI measurement) Pulse rate Blood pressure
  • 18. 2. IS THIS THE BEST ARTICLE FOR MY RESEARCH QUESTION? Remember… Problem/Patient Intervention Comparison Outcome Add… Date of Publication Times cited (Web of Knowledge, PSYCinfo, Google Scholar) Publication Type Source: Flahery, RJ. “A simple method for evaluating the clinical literature.” Family Practice Management. May 2004.
  • 20. PYRAMID OF PUBLICATION TYPES Guidelines Systematic Reviews Randomized Controlled Trials Cohort Studies Case Series, Case Reports Higher Quality of Information Fewer Articles Lower Quality of Information More Articles
  • 21. Date Times Cited Publication Type April 2006 69 (Web of Science) 71 (PsycINFO) 101 (Google Scholar) Randomized Control Trial (RCT)
  • 22. 3. DOES THIS ARTICLE RELY ON SOUND RESEARCH METHODOLOGIES? Critical Appraisal Charts for... • Systematic Reviews • Therapy Studies • Diagnosis Studies • Prognosis Studies • Harm/Etiology
  • 23. Randomization Allocation Concealment Similar Baseline Characteristics Blinding To what extent? Follow up Intention to Treat Yes (maybe); methods not described Not described Yes No Not described Yes
  • 24. SELECT 5 BEST ARTICLES 1. Does this article address my research question (PICO)? YES 2. Is this the best type of article for my research question? YES 3. Does this article rely on sound research methodologies? MOSTLY
  • 25. WHAT I AM LOOKING FOR ON THE ASSIGNMENT 1 Point – Reference 5 Articles 1 .75 .5 .25 0 List four or five articles that relate to the research question and relevant PICO elements. List three articles that relate to the research question and relevant PICO elements. List two articles that relate to the research question and relevant PICO elements. List one article that relates to the research question and relevant PICO elements. List no articles that relate to the research question and relevant PICO elements.
  • 26. WHAT I AM LOOKING FOR ON THE ASSIGNMENT 1 Point – Provide One Article that Meets Assessment Criteria 1 .5 0 At least one article listed meets assessment criteria of high quality evidence (combination of publication type, currency, statistics, times cited, aApt pleraaissta ol)n. e article listed meets some assessment criteria ranking it as medium quality evidence (combination of publication type, cNuor raernticcyle, ss tlaisttisetdic ms,e teimt aensy c aitsesde,s aspmpernatis carli)t.eria ranking all articles as low quality evidence.
  • 27. RESOURCES Citation Style LibGuide  Sample paper, cheat sheet, useful websites, examples, etc. http://norris.usc.libguides.com/citation Psychiatry LibGuide (Clerkship Resources)  Download PowerPoint, download “Simple Method for Evaluating Clinical Literature” article, access databases mentioned http://norris.usc.libguides.com/psychiatry
  • 28. CONTACT Lynn Kysh, MLIS Information Services Librarian (323) 442-1124 kysh@usc.edu
  • 29. LEARNING OBJECTIVES Formulate a clinical research question from clerkship experience Identify databases relevant to psychiatry and conduct an effective search Apply basic criteria to appraise evidence Retrieve available resources for more information on citation styles, search strategies, etc.