Complete 2012-13 Induced Pluripotent Stem Cell Industry Report:Industry Analysis Report @ http://www.researchmoz.us/complete-2012-13-induced-pluripotent-stem-cell-industry-report-report.html

1. Complete 2012-13 Induced Pluripotent Stem Cell Industry Report
Stem cell research and experimentation has been in process for well over five decades, as stem cells have the
unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows
them to differentiate into a wide variety of specialized cell types. The possibilities arising from these
characteristics have caused great commercial interest, with potential applications ranging from the use of stem
cells in reversal or treatment of disease, to targeted cell therapy, tissue regeneration, pharmacological testing
on cell-specific tissues, and more. Diseases such as Huntington’s Chorea, Parkinson’s Disease,
and spinal cord injuries are examples of clinical applications in which stem cells could offer benefits in halting
or even reversing damage.
Traditionally, scientists have worked with both embryonic and adult stem cells as research tools. While the
appeal of embryonic cells has been their ability to differentiate into any type of cell, there has been significant
ethical, moral and spiritual controversy surrounding their use for research purposes. Although some adult stem
cells do have differentiation capacity, it is often limited in nature, which creates narrow options for use. Thus,
induced pluripotent stem cells represent a promising combination of adult and embryonic stem cell
characteristics.
Discovery:
Groundbreaking experimentation in 2006 led to the introduction of induced pluripotent stem cells (iPSC).
These are adult cells which are isolated and then transformed into embryonic-like stem cells through the
manipulation of gene expression, as well as other methods. Research and experimentation using mouse cells at
Kyoto University in Japan was the first instance in which there was successful generation of the iPSC. In
2007, a series of follow-up experiments were done at Kyoto University in which human adult cells were
transformed into iPSC cells.
While there has been continued excitement at the prospect of what such artificially re-manufactured cells
could contribute to medical advances, there have also been issues along the way. By 2010, there were a
number of private companies that were ready to capitalize on the breakthrough technology that iPSCs
represent. One such company, Advanced Cell Technology in Worcester, Massachusetts, discovered several
problematic issues while conducting experiments for the purpose of applying for U.S. Food and Drug
Administration approval to use iPSCs in therapeutic applications. Concerns such as premature cell death,
mutation into cancer cells, and low proliferation rates were some of the problems that surfaced.
"Research Advances:
Continued research and experimentation has resulted in numerous advances over the last few years. In one
example, the University of Michigan announced in “Circulation Research” (2012) that they had
developed innovative methods for use of induced pluripotent stem cells derived from skin biopsies to create
cardiac muscle cells. This accomplishment quickly fueled other research into the use of iPSCs for the reversal
and repair of diseased heart tissue.
Similar advances will continue to be perfected for use of reprogrammed adult cells in the treatment of other
diseases and disorders. Original techniques for iPSC production, such as viral induced transcription processes,
are being replaced with newer technologies as private industries join with the scientific community to develop
safe and efficient methods of iPSC production. With sustained research and experimentation, established
guidelines for effective production of iPSCs will be commonplace. In summary, induced pluripotent stem cells
Complete 2012-13 Induced Pluripotent Stem Cell Industry Report

2. represent a promising tool for use in the reversal and repair of many previously incurable diseases.
Market Metrics - iPSC Research Products:
For this reason a large and thriving research products market has grown into existence for the cell type. The
number of iPSC research products sold worldwide has been growing at an annual rate of 14.7% for the past
five years. In addition, 22% of all stem cell researchers now self-report as having used induced pluripotent
stem cells within a research project. It is clear that iPSCs are a vital research trend within the scientific
community.
A distinctive feature of this report is an end-user survey of 293 researchers (181 U.S. / 112 International) that
identify as having induced pluripotent stem cells as their core research focus. These survey findings reveal
iPSC researcher needs, technical preferences, key factors influencing buying decisions, and more. They can be
used to make effective product development decisions, create targeted marketing messages, and produce
higher prospect-to-client conversion rates. Remember, to benefit from this lucrative product market, you need
to anticipate and serve the needs of your clients, or your competitors will.
Key Findings Include:
Charts, Timelines, and Financials for the iPSC Research Product Market Trends for iPSC Grants, Scientific
Publications, and Patents 5-Year Market Size Projections (2013-2017) Competitive Environment Analysis,
including Market Share by Competitor Preferred Species for iPSC Research iPSC Product Categories
(Breakdown of Market Share by Each) Consumer Behavioral Patterns and Preferred Providers Crucial Trends
and Unmet Market Needs “Tested Sentences” for Selling to iPSC Scientists Breakdown of the
Marketing Methods Used by Industry Participants End-User Survey of iPSC Researchers (181 U.S. / 112
International)" In summary, this is a must-read industry report for research supply companies to optimally
position themselves to sell iPSC products. To profit from this lucrative and rapidly expanding market, you
need to understand your key strengths relative to the competition, intelligently position your products to fill
gaps in the marketplace, and take advantage of crucial iPSC trends. Claim this report now to profit from this
expanding market - or your competition will.
table Of Content
"i. Abstract
ii. Background
a. Definition
b. Discovery
c. Advantages & Disadvantages
"
"iii. Timeline
a. Production Of Ipscs (key Events)
b. Full Timeline Of Events
iv. Research Applications
Complete 2012-13 Induced Pluripotent Stem Cell Industry Report

3. a. Pharmaco-toxicological Screening
b. Disease Modeling
c. Autologous Cell Transplantation
d. Breakdown Of Ipsc Research, By Applied Research Application
"v. Characterization Of Ipsc Research Advances
a. Methods Of Making Ipscs – Comparison Of Methods By Downstream Application
b. Summary Of Ipsc Derivation Methods, By Cell Type
c. Diseases In Which Ispcs Have Been Derived From Patients
"
"vi. Companies Selling Ipsc Research Products
a. List Of Companies
b. Rate Of Entrants By Year
vii. Types Of Ipsc Research Products
a. Stem Cell Product Categories
b. Ipsc Market Share Breakdown, By Product Area
"
"viii. Companies Developing Ipsc Therapies
a. Commerical Entities
1. Viacyte
2. Fate Therapeutic
3. Iperian
4. Cellular Dynamics
5. Mesoblast
b. Non-commercial Organizations Developing Ipsc Therapies
"
"ix. Strategic Collaborations For Development Of Ipsc Products
a. Life Technologies
b. Lonza Group Ag
c. Emd Millipore
d. Sigma Aldrich
e. Roslin Cells, Ltd.
f. Aruna Biomedical
g. Ceetox And Cellular Dynamics
x. Market Trend Analysis
a. Clinical Trials+e16
b. Grant Analysis
1. Historical Analysis
Complete 2012-13 Induced Pluripotent Stem Cell Industry Report

4. 2. Future 5-year Projection
c. Patent Analysis
d. Scientific Publication Analysis
1. Historical Data
2. Future 5-year Projections
3. Comparison Of Ipsc Research Frequency, Relative To Other Cell Types
e. Search Phrase Analysis
1. Induced Pluripotent Stem Cell Search Terms
2. Induced Pluripotent Stem Cell “google” Search Analysis
f. Geographical Analysis: Domestic Vs. International Status
1. Number Of Ipsc Labs, By Region Of World
2. Percent Of Total Ipsc-specific Research Funding, By Region Of World
g. Additional Sources Of Ipsc Research Funding
"xi. Market Size
a. Definition: Ipsc Research Products
b. Experimental Approach
c. Ipsc Research Products, Market Size
d. Ipsc Research Products, 5-year Market Projections
xii. Scientist Panel: Detailed End-user Survey
a. Survey Overview
b. Characterization Of Market Survey Respondents
1. Geographic Distribution Of Respondents
2. Respondent Breakdown By Industry Affiliation
3. Breakdown Of Respondents By Duration Of Ipsc Research Activity
"c. Survey Findings
1. General Scope
2. Comparison Of Providers / Brand Preferences
3. Marketing Assessment
d. Terms Used In Online Product Search
xiii. Strategies For Accessing The Marketplace
a. Top Research Institutions Performing Stem Cell Research
1. University Of Wisconsin, Including Warf, Wicell, And The Wisc Bank
2. Us National Institutes Of Health (nih)
3. Johns Hopkins University
4. California Institute For Regenerative Medicine
5. University Of Connecticut Induced Pluripotent Stem Cell Core (ipscc)
b. Events Of Interest (2012-13)
Complete 2012-13 Induced Pluripotent Stem Cell Industry Report

5. xiv. Conclusions
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Complete 2012-13 Induced Pluripotent Stem Cell Industry Report