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Nmr mujtaba

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Nmr mujtaba

  1. 1. PRESENTATION ON: NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (NMR) INTEGRAL UNIVERSITY,LUCKNOW Session: 2016-2017 Presented by: Under the guidence of: Mohd Muztaba M.Pharm Mr. Paramdeep Bagga Pharmacology
  2. 2. INTRODUCTION  Nuclear magnetic resonance spectroscopy(NMR) is a powerful analytical technique used to characterize organic molecules by identifying carbon-hydrogen frameworks within molecules.  It is a research technique that exploits the magnetic properties of certain atomic nuclei.  It determines the physical and chemical properties of atoms or the molecules in which they are contained.
  3. 3. Types of NMR • Two common types of NMR spectroscopy are used to characterize organic structure: – 1H NMR:- Used to determine the type and number of H atoms in a molecule – 13C NMR:- Used to determine the type of carbon atoms in the molecule
  4. 4. • The theory behind NMR comes from the spin of a nucleus and it generates a magnetic field. • Without an external applied magnetic field, the nuclear spins are random in directions. • But when an external magnetic field (BO) is present, the nuclei align themselves either with or against the field of the external magnet. Principles of NMR
  5. 5.  If an external magnetic field is applied, an energy transfer (∆E) is possible between ground state to excited state  When the spin returns to its ground state level, the absorbed radiofrequency energy is emitted at the same frequency level.  The emitted radiofrequency signal gives the NMR spectrum of the concerned nucleus.
  6. 6. APPLICATION  It is use to identification of structrul isomertism eg. n-propanol ,isopropanol  Identification of H bonding  Use for determination of aromaticities of compound  NMR technique use to distinguish betweeen cis and trans isomer  Detection of Electronegative atom  Detection of some double bond character due to resonance
  7. 7. We hope you liked our presentation. • Thank you! 