1. MALIGNANT NEOPLASMS OF
NASAL CAVITY
BY: MOHIT KADYAN
ROLL NO: 26

2. TUMORS OF NASAL CAVITY
CARCINOMA OF NASAL CAVITY
-SQUAMOUS CELL CARCINOMA
-ADENOCARCINOMA
MALIGNANT MELANOMA
OLFACTORY NEUROBLASTOMA
LYMPHOMA
PLASMACYTOMA
OTHERS SARCOMA AND HAEMANGIOPERICYTOMA

3. 1. SQUAMOUS CELL CARCINOMA
• It is the most common variety , seen in about 80% of cases
• Above 50 years of age
• It may arise from -vestibule,
-anterior part of nasal septum or
-lateral wall of nasal cavity.
• Vestibular: arises from lateral wall of vestibule and extends into
collumela , nasal floor, and upper lip .
• Septal: arises from mucocutaneous junction causing burning and
sore nose . It is termed as “nose-picker’s cancer’’.
• Lateral wall: most common site , extends into ethmoid or
maxillary sinus , presents as polypoidal mass in lateral wall of
nose

5. • Vestibular spreads to parotid nodes while septal
and lateral wall neoplasms show low metastatic
tendency.
Treatment:
Combination of radiotherapy and surgery
Metastasis:

6. Adenocarcinoma and adenoid
cystic carcinoma.
•They arise from the glands of
mucous membranes , mostly involve
upper part of the lateral wall of nasal
cavity.

7. 2. Malignant melanoma
• Usually seen in persons about 50 yrs of age.
• Cell of origion is MELANOCYTE
• It presents as slaty-gray or bluish-black polypoid
mass.
• Anterior part is most common site followed by
middle and inferior turbinate.
• Amelanotic are the non-pigmented varieties

8. METASTASIS:
• Tumour spreads to cervical nodes by blood
and lymphatic route
TREATMENT:
• Surgical incision is the treatment , radiotherapy and
chemotherapy are avoided as it supresses immunity

9. 3. Olfactory neuroblastoma
• Tumour of olfactory placode can be seen in
any age group.
• Cherry red , polypoidal mass in upper nasal
cavity.
• Bleeds on biopsy as it is highly vascular.

10. Metastasis:
• Lymph node or systemic metastasis can occur
Treatment:
• Can be cured by radiotherapy alone
• Surgical excision is followed presently along with radiation
• Craniofacial resection may be required for tumors of
cribriform plate.

11. 4.Haemangiopericytoma
• Rare tumour of vascular origin seen in 60-70 yrs of
age.
• Cell of origion is ‘’pericyte’’ which surround
capillaries
• Patients present with epistaxis
• Tumour bleeds on biopsy
• Treatment is surgical excision and radiotherapy is
tried for recurrent and inoperable cases.

12. 5. Plasmocytoma
• Affects males over 40 yrs of age
• Solitary plasmocytoma without any osseous
disease can be seen in the nasal cavity
• Treatment is by radiation followed 3 months
later by surgery , if regression doesn’t occur
• long term follow up is advised to exclude
development of Multiple myeloma.

13. 6. Sarcomas
• Osteogenic sarcoma , chondrosarcoma,
rhabdomyosarcoma , angiosarcoma ,
malignant histiocytoma are other rare
tumours affecting the nose.

14. 7. lymphoma
• Rarely a non-hodgkin lymphoma presents on
septum of nose.

15. Thank You