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CHAPTER 13

SOLUTIONS
PART 4

LINIMENTS,
COLLODIONS,
GLYCERITES
    Prepared by:
    Asst. Prof. MA. LOURDES L.
    MOJARES, R. Ph.
LINIMENTS
   Formerly called EMBROCATIONS
   Are alcoholic or oleaginous solution or
    emulsion of various medicinal
    substances intended for external
    application to the skin, generally with
    rubbing.

   Must bear a label indicating
    “FOR EXTERNAL USE ONLY”
      “ Not to be applied to broken skin”
TYPES OF LINIMENTS
1. Alcoholic Liniments

  Used for its rubefacient property

2. Oily Liniments
   Useful when massage is required

3. Emulsion Liniment
TYPES OF LINIMENTS
EXAMPLES:

1.   White Liniment, BPC
     (emulsion type)
2.   Camphor Liniment (emulsion
     type)
3.   Efficascent Oil (oily type)
4.   Omega Pain Killer (emulsion
     type)
LINIMENTS / EMBROCATIONS
COLLODIONS

   Ethereal solutions

   Are liquid preparations
    composed of PYROXILLIN
    (soluble gun cotton, collodion
    cotton) dissolved in a solvent
    mixture usually composed of
    alcohol and ether with or
    without added medicinal
COLLODIONS

   Intended for external use only

   Applied to the skin with a fine
    camel’s hair brush or glass
    applicator

   Stored in a tight-closed container
    at a temperature not exceeding
GLASS APPLICATOR BOTTLE
Examples and Uses of
        Collodions

I. COLLODION, USP
   Useful in holding the edges of
    an incised wound together

   Has a disadvantage of being
    non-flexible
Examples and Uses of
        Collodions
II. FLEXIBLE COLLODION, USP
   Prepared by adding 2%
    camphor and 3% castor oil

III. SALICYLIC ACID
    COLLODION, USP
   A 10% salicylic acid in Flexible
    Collodion
GLYCERITES
   Are viscous solutions or mixtures
    of medicinal substances in NOT
    LESS THAN 50% by weight of
    GLYCERIN

   Used as a medicinal agent or as
    an aid in dissolving other drugs
    in water or alcohol.
   Starch Glycerite – pill excipient
GLYCERITES
Examples:

1.   Starch glycerite - topical
     protective
2.   Tannic Acid glycerite -
     astringent
3.   Phenol glycerite
GLYCERITES
   FORMULATION
    COMPONENTS:

     1. Glycerin – nlt 50% w/w
     2. Purified water
     3. Gelatin
     4. Medicament (active
    ingredient)
OLEOVITAMINS

   Vitamins A and D, and in some
    preparations , Vitamin E, in fish
    liver oil

   Used as Antirachitic

   COD LIVER OIL (Oleovitamin A
    and D)
OLEOVITAMINS
TOOTHACHE
    DROPS
   Preparations used for the
    temporary relief of toothache

   Applied using a small pledget of
    cotton saturated with the product
    into the tooth cavity

   Contains clove oil and mixtures of
    phenol with camphor or creosote
TOOTHACHE DROPS

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Ch.13 part 4 liniment, collodion, glycerite

  • 1. CHAPTER 13 SOLUTIONS PART 4 LINIMENTS, COLLODIONS, GLYCERITES Prepared by: Asst. Prof. MA. LOURDES L. MOJARES, R. Ph.
  • 2. LINIMENTS  Formerly called EMBROCATIONS  Are alcoholic or oleaginous solution or emulsion of various medicinal substances intended for external application to the skin, generally with rubbing.  Must bear a label indicating “FOR EXTERNAL USE ONLY” “ Not to be applied to broken skin”
  • 3. TYPES OF LINIMENTS 1. Alcoholic Liniments Used for its rubefacient property 2. Oily Liniments Useful when massage is required 3. Emulsion Liniment
  • 4. TYPES OF LINIMENTS EXAMPLES: 1. White Liniment, BPC (emulsion type) 2. Camphor Liniment (emulsion type) 3. Efficascent Oil (oily type) 4. Omega Pain Killer (emulsion type)
  • 6. COLLODIONS  Ethereal solutions  Are liquid preparations composed of PYROXILLIN (soluble gun cotton, collodion cotton) dissolved in a solvent mixture usually composed of alcohol and ether with or without added medicinal
  • 7. COLLODIONS  Intended for external use only  Applied to the skin with a fine camel’s hair brush or glass applicator  Stored in a tight-closed container at a temperature not exceeding
  • 9. Examples and Uses of Collodions I. COLLODION, USP  Useful in holding the edges of an incised wound together  Has a disadvantage of being non-flexible
  • 10. Examples and Uses of Collodions II. FLEXIBLE COLLODION, USP  Prepared by adding 2% camphor and 3% castor oil III. SALICYLIC ACID COLLODION, USP  A 10% salicylic acid in Flexible Collodion
  • 11. GLYCERITES  Are viscous solutions or mixtures of medicinal substances in NOT LESS THAN 50% by weight of GLYCERIN  Used as a medicinal agent or as an aid in dissolving other drugs in water or alcohol.  Starch Glycerite – pill excipient
  • 12. GLYCERITES Examples: 1. Starch glycerite - topical protective 2. Tannic Acid glycerite - astringent 3. Phenol glycerite
  • 13. GLYCERITES  FORMULATION COMPONENTS: 1. Glycerin – nlt 50% w/w 2. Purified water 3. Gelatin 4. Medicament (active ingredient)
  • 14. OLEOVITAMINS  Vitamins A and D, and in some preparations , Vitamin E, in fish liver oil  Used as Antirachitic  COD LIVER OIL (Oleovitamin A and D)
  • 16. TOOTHACHE DROPS  Preparations used for the temporary relief of toothache  Applied using a small pledget of cotton saturated with the product into the tooth cavity  Contains clove oil and mixtures of phenol with camphor or creosote