Vascular Sys Student Notes

Acute Control of Local Blood Flow ,[object Object],[object Object],[object Object],[object Object],[object Object]

Effect of Tissue Metabolic Rate on Tissue Blood Flow Figure 17-1; Guyton and Hall Tissue Metabolism Blood Flow

Effect of Tissue Oxygen Concentration on Blood Flow Figure 17-2; Guyton and Hall Tissue Oxygen Concentration Blood Flow

Vasodilator Theory for Blood Flow Control ,[object Object],TISSUE METABOLISM BLOOD FLOW ARTERIOLE RESISTANCE RELEASE OF VASODILATORS

Oxygen Demand Theory for Blood Flow Control TISSUE METABOLISM OR OXYGEN DELIVERY TO TISSUES ARTERIOLE RESISTANCE TISSUE OXYGEN CONCENTRATION BLOOD FLOW

Local Control of Blood Flow ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Humoral Regulation of Blood Flow ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Blood Flow Autoregulation Theories ,[object Object],[object Object]

Blood Flow Autoregulation Theories ,[object Object],[object Object],[object Object]

Venous Pressure in the Body ,[object Object],[object Object]

Starling Forces ,[object Object],[object Object],[object Object],[object Object]

Structure of Capillary Wall ,[object Object],[object Object],[object Object],Figure 16-2; Guyton and Hall

Effect of Molecular Size on Passage Through Capillary Pores ,[object Object],[object Object],[object Object],[object Object],Figure 16-2; Guyton and Hall

Variations in Tissue Blood Flow Brain 14 700 50 Heart 4 200 70 Bronchi 2 100 25 Kidneys 22 1100 360 Liver 27 1350 95 Portal (21) (1050) Arterial (6) (300) Muscle (inactive state) 15 750 4 Bone 5 250 3 Skin (cool weather) 6 300 3 Thyroid gland 1 50 160 Adrenal glands 0 .525 300 Other tissues 3.5 175 1.3 Total 100.0 5000 --- Percent ml/min ml/min/ 100 gm

Blood Pressure Profile in the Circulatory System Systemic Pulmonary Aorta Large arteries Small arteries Arterioles Capillaries Pressure (mmHg) 0 2 0 4 0 6 0 8 0 1 0 0 1 2 0 Venules Small viens Large viens Venae cavae Pulmonary arteries ,[object Object],[object Object],[object Object],Arterioles Capillaries Venules Pulmonary viens

Blood Flow ,[object Object],[object Object],[object Object],Blood Vessel

Characteristics of Blood Flow ,[object Object],[object Object],Blood Vessel Laminar flow

Laminar Vs. Turbulent Blood Flow Turbulent flow ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Damping of Pulse Pressures in the Peripheral Arteries ,[object Object],[object Object],Figure 15-6; Guyton and Hall

Abnormal Pressure Pulse Contours Figure 15-4; Guyton and Hall

Abnormal Pressure Pulse Contours ,[object Object],[object Object],[object Object]

Abnormal Pressure Pulse Contours ,[object Object],[object Object],[object Object],[object Object]

Abnormal Pressure Pulse Contours ,[object Object],[object Object],[object Object],[object Object],[object Object]

Regarding these vessels’ sizes: ,[object Object],[object Object],[object Object],[object Object]

ARTERIAL End’s Net Starling Force ( pos. is outward, neg. is inward ): Cap. Hydro. Press. = +28 ( + because it’s an outward force) Plasma Coll. Osm. Press. = –29 ( – because it’s inward ) Interstitial Tiss. Press. = – (– 3) = +3 ( – because it’s inward) Interstitial Colloid Osm. Press. = +8 ( + because it’s outward) Sum total = net Starling Force = +10 mm Hg (an outward force)

VENOUS End’s Net Starling Force ( pos. is outward, neg. is inward ): Cap. Hydro. Press. = Plasma Coll. Osm. Press. = Interstitial Tiss. Press. = Interstitial Colloid Osm. Press. = Sum total = net Starling Force =

Vascular Sys Student Notes

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