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99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
A	
  liver	
  cancer	
  diagnosis	
  can	
  be	
  scary.	
  
	
  
Learn	
  more	
  about	
  liver	
  cancer	
  and	
  how	
  we	
  can	
  help.	
  
	
  

Please	
  note:	
  We	
  encourage	
  consumers	
  to	
  thoroughly	
  review	
  and	
  understand	
  all	
  treatment	
  op8ons.	
  
The	
  informa8on	
  presented	
  here	
  is	
  not	
  all-­‐inclusive.	
  Rather,	
  it	
  represents	
  a	
  star8ng	
  point	
  to	
  learn	
  
more	
  about	
  medical	
  condi8ons	
  and	
  treatment	
  op8ons.	
  There	
  is	
  no	
  subs,tute	
  for	
  consul,ng	
  a	
  
medical	
  professional.	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
About	
  Liver	
  Cancer	
  
The	
  liver	
  is	
  the	
  largest	
  internal	
  organ.	
  It	
  lies	
  under	
  your	
  right	
  
ribs	
  just	
  beneath	
  your	
  right	
  lung.	
  It	
  is	
  shaped	
  like	
  a	
  pyramid	
  and	
  
divided	
  into	
  right	
  and	
  le9	
  lobes	
  which	
  are	
  further	
  divided	
  into	
  
segments.	
  	
  
	
  
The	
  liver	
  gets	
  blood	
  from	
  the	
  hepa=c	
  artery	
  and	
  the	
  portal	
  vein	
  
and	
  is	
  made	
  up	
  of	
  mainly	
  hepatocyte	
  cells.	
  The	
  different	
  types	
  
of	
  cells	
  in	
  the	
  liver	
  can	
  for	
  several	
  types	
  of	
  malignant	
  and	
  
benign	
  tumors.	
  
	
  
	
  About	
  21,000	
  Americans	
  are	
  diagnosed	
  with	
  primary	
  liver	
  
cancer	
  each	
  year	
  and	
  is	
  twice	
  as	
  common	
  in	
  men	
  than	
  in	
  
women.	
  	
  
	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
Types	
  of	
  Liver	
  Cancer	
  
A	
  cancer	
  that	
  starts	
  in	
  the	
  liver	
  is	
  called	
  primary	
  liver	
  cancer.	
  Here	
  are	
  the	
  types	
  of	
  
primary	
  liver	
  cancer:	
  
	
  
•  Hepatocellular	
  carcinoma	
  (hepatocellular	
  cancer)	
  
•  Intrahepa=c	
  cholangiocarcinoma	
  (bile	
  duct	
  cancer)	
  
•  Angiosarcoma	
  and	
  hemangiosarcoma	
  	
  	
  
•  Hepatoblastoma	
  	
  
	
  
For	
  more	
  informa=on	
  on	
  the	
  types	
  of	
  primary	
  liver	
  cancer,	
  as	
  well	
  as	
  informa=on	
  on	
  
secondary	
  liver	
  cancer,	
  click	
  here.	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
Risk	
  Factors	
  of	
  Liver	
  Cancer	
  
There	
  is	
  no	
  single	
  cause	
  of	
  liver	
  cancer,	
  though	
  there	
  are	
  several	
  known	
  risk	
  
factors:	
  
	
  
•  Gender	
  –	
  Seen	
  more	
  o9en	
  in	
  men.	
  
•  Age	
  –	
  Risks	
  generally	
  increase	
  for	
  older	
  men.	
  
•  Race	
  –	
  Asian	
  Americans	
  and	
  Pacific	
  Islanders	
  have	
  a	
  higher	
  risk	
  for	
  unknown	
  
reasons	
  followed	
  by	
  American	
  Indians/Alaska	
  Na=ves	
  and	
  Hispanic/La=nos,	
  
African	
  Americans	
  and	
  whites.	
  	
  
•  NaAonality	
  –	
  much	
  more	
  common	
  in	
  countries	
  in	
  sub-­‐Saharan	
  Africa	
  and	
  
Southeast	
  Asia	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
Risk	
  Factors	
  of	
  Liver	
  Cancer	
  
•  Cirrhosis	
  	
  
•  Chronic	
  viral	
  hepaAAs	
  
•  Heavy	
  alcohol	
  use	
  	
  
•  Obesity	
  	
  
•  Type	
  2	
  diabetes	
  
•  Inherited	
  metabolic	
  diseases	
  
•  Alfatoxins	
  	
  
•  Arsenic	
  	
  
•  InfecAon	
  with	
  parasites	
  

For	
  full	
  descrip=ons	
  of	
  these	
  risk	
  factors,	
  click	
  here.	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
What	
  are	
  symptoms	
  of	
  liver	
  cancer?	
  
•  Signs	
  and	
  symptoms	
  of	
  liver	
  cancer	
  o9en	
  do	
  not	
  show	
  up	
  un=l	
  the	
  later	
  stages	
  of	
  the	
  disease.	
  
•  Most	
  common	
  symptoms	
  are:	
  
•  Weight	
  loss	
  (without	
  trying)	
  
•  Loss	
  of	
  appe=te	
  
•  Feeling	
  very	
  full	
  a9er	
  a	
  small	
  meal	
  
•  Nausea	
  or	
  vomi=ng	
  
•  An	
  enlarged	
  liver,	
  felt	
  as	
  a	
  mass	
  under	
  ribs	
  on	
  the	
  right	
  side	
  
•  An	
  enlarged	
  spleen,	
  felt	
  as	
  a	
  mass	
  under	
  the	
  ribs	
  on	
  the	
  le9	
  side	
  
•  Pain	
  in	
  the	
  abdomen	
  or	
  near	
  the	
  right	
  shoulder	
  blade	
  
•  Swelling	
  or	
  fluid	
  build-­‐up	
  in	
  the	
  abdomen	
  
•  Itching	
  
•  Yellowing	
  of	
  the	
  skin	
  and	
  eyes	
  (jaundice)	
  
•  Chronic	
  hepa==s	
  or	
  cirrhosis	
  are	
  also	
  common	
  causes	
  which	
  may	
  cause	
  the	
  person	
  to	
  feel	
  worse	
  than	
  

usual	
  or	
  have	
  a	
  change	
  in	
  lab	
  results.	
  	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
How	
  does	
  CyberKnife	
  treat	
  liver	
  cancer?	
  
Prior	
  to	
  stereotac=c	
  body	
  radiosurgery	
  treatment	
  with	
  CyberKnife,	
  small	
  
=ssue	
  markers	
  known	
  as	
  fiducials	
  are	
  implanted	
  in	
  the	
  liver	
  to	
  help	
  the	
  
CyberKnife	
  pinpoint	
  the	
  tumor	
  loca=on	
  throughout	
  each	
  treatment,	
  so	
  the	
  
radia=on	
  beams	
  can	
  be	
  locked	
  on	
  the	
  tumor.	
  	
  
	
  
About	
  a	
  week	
  later,	
  pa=ents	
  are	
  fiXed	
  with	
  a	
  custom	
  body	
  mold	
  of	
  so9	
  
material	
  that	
  they	
  lie	
  on	
  during	
  treatments.	
  The	
  fiYng	
  process	
  is	
  painless.	
  
	
  
The	
  treatment	
  process	
  includes:	
  
I.  Consulta=on	
  appointment	
  
II.  Pretreatment	
  procedures	
  
III.  CyberKnife	
  treatment	
  
IV.  Follow-­‐up	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
ConsultaAon	
  and	
  Pretreatment	
  Procedures	
  
New	
  Jersey	
  CyberKnife	
  physicians,	
  therapists	
  and	
  nurses	
  are	
  
focused	
  on	
  your	
  individualized	
  treatment	
  plan:	
  
	
  
•  You	
  will	
  meet	
  a	
  New	
  Jersey	
  CyberKnife	
  radia=on	
  
oncologist	
  to	
  decide	
  if	
  CyberKnife	
  treatment	
  is	
  
appropriate	
  for	
  your	
  diagnosis.	
  	
  
	
  
•  Your	
  CyberKnife	
  team	
  will	
  decide	
  which	
  pretreatment	
  
procedures	
  you	
  may	
  need	
  to	
  help	
  develop	
  your	
  
treatment	
  plan.	
  These	
  could	
  include	
  a	
  CT	
  scan,	
  an	
  MRI,	
  
laboratory	
  studies	
  or	
  =ssue	
  markers.	
  	
  
	
  
•  The	
  data	
  from	
  your	
  pretreatment	
  procedures	
  will	
  be	
  
used	
  by	
  the	
  CyberKnife	
  team	
  to	
  determine	
  the	
  exact	
  size,	
  
shape	
  and	
  loca=on	
  of	
  your	
  tumor.	
  
• 

	
  

This	
  informa=on	
  will	
  indicate	
  the	
  size	
  of	
  the	
  area	
  being	
  
treated	
  with	
  radia=on,	
  the	
  radia=on	
  dose	
  and	
  cri=cal	
  
structures	
  where	
  radia=on	
  exposure	
  should	
  be	
  
minimized.	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
CyberKnife	
  Treatment	
  
Typically	
  treatment	
  is	
  completed	
  within	
  five	
  sessions.	
  
On	
  the	
  day	
  of	
  your	
  treatment:	
  	
  
	
  
1.  A	
  therapist	
  will	
  help	
  you	
  onto	
  the	
  treatment	
  table	
  
and	
  fit	
  the	
  body	
  mold.	
  Pa=ents	
  are	
  observed	
  
throughout	
  the	
  treatment	
  on	
  closed-­‐circuit	
  
television,	
  and	
  they	
  can	
  pause	
  treatment	
  at	
  any	
  
=me	
  by	
  waving	
  or	
  speaking	
  to	
  the	
  technicians.	
  
2. 

3. 

While	
  the	
  CyberKnife’s	
  advanced	
  tracking	
  system	
  
accounts	
  for	
  movements	
  like	
  breathing,	
  you’re	
  
asked	
  to	
  lie	
  s=ll	
  during	
  treatments.	
  The	
  system	
  
periodically	
  takes	
  x-­‐ray	
  images	
  and	
  compares	
  them	
  
to	
  the	
  CT	
  scan	
  data	
  to	
  make	
  sure	
  the	
  radia=on	
  
beam	
  is	
  locked	
  on	
  the	
  tumor.	
  
Pa=ents	
  can	
  usually	
  return	
  to	
  their	
  normal	
  rou=nes	
  
once	
  the	
  treatment	
  is	
  complete.	
  

99 Route 37, West Toms River, NJ 08755

FOR	
  YOUR	
  INFORMATION	
  
•  Treatment	
  procedures	
  take	
  about	
  30	
  –	
  90	
  
minutes,	
  depending	
  on	
  the	
  complexity	
  of	
  your	
  
tumor.	
  
•  Pa=ents	
  are	
  asked	
  to	
  wear	
  comfortable	
  clothing	
  
during	
  CyberKnife	
  treatments.	
  Jewelry	
  is	
  
acceptable	
  unless	
  it	
  is	
  close	
  to	
  the	
  area	
  being	
  
treated.	
  
•  Feel	
  free	
  to	
  bring	
  an	
  iPod®	
  or	
  your	
  favorite	
  
music	
  CDs	
  with	
  you	
  on	
  the	
  day	
  of	
  your	
  
treatment,	
  and	
  we	
  will	
  play	
  them	
  for	
  you	
  during	
  
the	
  procedure.	
  

(732) 557-3120

www.newjerseyck.com
AddiAonal	
  Resources	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com
Our	
  Center	
  
Opened	
  in	
  2011,	
  New	
  Jersey	
  CyberKnife	
  at	
  the	
  J.	
  Phillip	
  CiXa	
  Regional	
  Cancer	
  Center	
  is	
  ac=ve	
  in	
  clinical	
  research	
  and	
  combines	
  
experienced	
  physicians	
  with	
  the	
  latest	
  medical	
  advances.	
  Our	
  state-­‐of-­‐the-­‐art	
  technology	
  offers	
  hope	
  to	
  pa=ents	
  in	
  New	
  Jersey	
  and	
  
beyond.	
  Medical	
  Director	
  Dr.	
  David	
  D’Ambrosio	
  specialized	
  in	
  advanced	
  radia=on	
  therapies	
  and	
  his	
  exper=se	
  includes	
  intensity-­‐
modulated	
  and	
  stereotac=c	
  radia=on	
  therapies,	
  including	
  CyberKnife	
  radiosurgery.Our	
  center	
  provides	
  the	
  only	
  CyberKnife	
  
technology	
  in	
  Ocean	
  County	
  New	
  Jersey.	
  
	
  
If	
  you	
  or	
  a	
  loved	
  one	
  is	
  diagnosed	
  with	
  liver	
  cancer,	
  contact	
  New	
  Jersey	
  CyberKnife	
  to	
  schedule	
  a	
  consulta=on	
  with	
  our	
  physicians	
  
to	
  determine	
  the	
  best	
  next	
  step	
  for	
  your	
  treatment	
  needs.	
  
	
  

Medical	
  Director:	
  Dr.	
  David	
  D’Ambrosio	
  
	
  
Chairman	
  of	
  RadiaAon	
  Oncology	
  at	
  Community	
  Medical	
  
Center:	
  Dr.	
  Rajesh	
  Iyer	
  
	
  
CyberKnife	
  Nurse:	
  Debbie	
  Moriarty,	
  RN,	
  MSN,	
  OCN	
  
	
  
	
  
Connect	
  with	
  us	
  
	
  
	
  

99 Route 37, West Toms River, NJ 08755

(732) 557-3120

www.newjerseyck.com

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Liver Cancer: CyberKnife Treatment Overview

  • 1. 99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 2. A  liver  cancer  diagnosis  can  be  scary.     Learn  more  about  liver  cancer  and  how  we  can  help.     Please  note:  We  encourage  consumers  to  thoroughly  review  and  understand  all  treatment  op8ons.   The  informa8on  presented  here  is  not  all-­‐inclusive.  Rather,  it  represents  a  star8ng  point  to  learn   more  about  medical  condi8ons  and  treatment  op8ons.  There  is  no  subs,tute  for  consul,ng  a   medical  professional.   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 3. 99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 4. About  Liver  Cancer   The  liver  is  the  largest  internal  organ.  It  lies  under  your  right   ribs  just  beneath  your  right  lung.  It  is  shaped  like  a  pyramid  and   divided  into  right  and  le9  lobes  which  are  further  divided  into   segments.       The  liver  gets  blood  from  the  hepa=c  artery  and  the  portal  vein   and  is  made  up  of  mainly  hepatocyte  cells.  The  different  types   of  cells  in  the  liver  can  for  several  types  of  malignant  and   benign  tumors.      About  21,000  Americans  are  diagnosed  with  primary  liver   cancer  each  year  and  is  twice  as  common  in  men  than  in   women.       99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 5. Types  of  Liver  Cancer   A  cancer  that  starts  in  the  liver  is  called  primary  liver  cancer.  Here  are  the  types  of   primary  liver  cancer:     •  Hepatocellular  carcinoma  (hepatocellular  cancer)   •  Intrahepa=c  cholangiocarcinoma  (bile  duct  cancer)   •  Angiosarcoma  and  hemangiosarcoma       •  Hepatoblastoma       For  more  informa=on  on  the  types  of  primary  liver  cancer,  as  well  as  informa=on  on   secondary  liver  cancer,  click  here.   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 6. Risk  Factors  of  Liver  Cancer   There  is  no  single  cause  of  liver  cancer,  though  there  are  several  known  risk   factors:     •  Gender  –  Seen  more  o9en  in  men.   •  Age  –  Risks  generally  increase  for  older  men.   •  Race  –  Asian  Americans  and  Pacific  Islanders  have  a  higher  risk  for  unknown   reasons  followed  by  American  Indians/Alaska  Na=ves  and  Hispanic/La=nos,   African  Americans  and  whites.     •  NaAonality  –  much  more  common  in  countries  in  sub-­‐Saharan  Africa  and   Southeast  Asia   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 7. Risk  Factors  of  Liver  Cancer   •  Cirrhosis     •  Chronic  viral  hepaAAs   •  Heavy  alcohol  use     •  Obesity     •  Type  2  diabetes   •  Inherited  metabolic  diseases   •  Alfatoxins     •  Arsenic     •  InfecAon  with  parasites   For  full  descrip=ons  of  these  risk  factors,  click  here.   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 8. What  are  symptoms  of  liver  cancer?   •  Signs  and  symptoms  of  liver  cancer  o9en  do  not  show  up  un=l  the  later  stages  of  the  disease.   •  Most  common  symptoms  are:   •  Weight  loss  (without  trying)   •  Loss  of  appe=te   •  Feeling  very  full  a9er  a  small  meal   •  Nausea  or  vomi=ng   •  An  enlarged  liver,  felt  as  a  mass  under  ribs  on  the  right  side   •  An  enlarged  spleen,  felt  as  a  mass  under  the  ribs  on  the  le9  side   •  Pain  in  the  abdomen  or  near  the  right  shoulder  blade   •  Swelling  or  fluid  build-­‐up  in  the  abdomen   •  Itching   •  Yellowing  of  the  skin  and  eyes  (jaundice)   •  Chronic  hepa==s  or  cirrhosis  are  also  common  causes  which  may  cause  the  person  to  feel  worse  than   usual  or  have  a  change  in  lab  results.     99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 9. 99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 10. How  does  CyberKnife  treat  liver  cancer?   Prior  to  stereotac=c  body  radiosurgery  treatment  with  CyberKnife,  small   =ssue  markers  known  as  fiducials  are  implanted  in  the  liver  to  help  the   CyberKnife  pinpoint  the  tumor  loca=on  throughout  each  treatment,  so  the   radia=on  beams  can  be  locked  on  the  tumor.       About  a  week  later,  pa=ents  are  fiXed  with  a  custom  body  mold  of  so9   material  that  they  lie  on  during  treatments.  The  fiYng  process  is  painless.     The  treatment  process  includes:   I.  Consulta=on  appointment   II.  Pretreatment  procedures   III.  CyberKnife  treatment   IV.  Follow-­‐up   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 11. ConsultaAon  and  Pretreatment  Procedures   New  Jersey  CyberKnife  physicians,  therapists  and  nurses  are   focused  on  your  individualized  treatment  plan:     •  You  will  meet  a  New  Jersey  CyberKnife  radia=on   oncologist  to  decide  if  CyberKnife  treatment  is   appropriate  for  your  diagnosis.       •  Your  CyberKnife  team  will  decide  which  pretreatment   procedures  you  may  need  to  help  develop  your   treatment  plan.  These  could  include  a  CT  scan,  an  MRI,   laboratory  studies  or  =ssue  markers.       •  The  data  from  your  pretreatment  procedures  will  be   used  by  the  CyberKnife  team  to  determine  the  exact  size,   shape  and  loca=on  of  your  tumor.   •    This  informa=on  will  indicate  the  size  of  the  area  being   treated  with  radia=on,  the  radia=on  dose  and  cri=cal   structures  where  radia=on  exposure  should  be   minimized.   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 12. CyberKnife  Treatment   Typically  treatment  is  completed  within  five  sessions.   On  the  day  of  your  treatment:       1.  A  therapist  will  help  you  onto  the  treatment  table   and  fit  the  body  mold.  Pa=ents  are  observed   throughout  the  treatment  on  closed-­‐circuit   television,  and  they  can  pause  treatment  at  any   =me  by  waving  or  speaking  to  the  technicians.   2.  3.  While  the  CyberKnife’s  advanced  tracking  system   accounts  for  movements  like  breathing,  you’re   asked  to  lie  s=ll  during  treatments.  The  system   periodically  takes  x-­‐ray  images  and  compares  them   to  the  CT  scan  data  to  make  sure  the  radia=on   beam  is  locked  on  the  tumor.   Pa=ents  can  usually  return  to  their  normal  rou=nes   once  the  treatment  is  complete.   99 Route 37, West Toms River, NJ 08755 FOR  YOUR  INFORMATION   •  Treatment  procedures  take  about  30  –  90   minutes,  depending  on  the  complexity  of  your   tumor.   •  Pa=ents  are  asked  to  wear  comfortable  clothing   during  CyberKnife  treatments.  Jewelry  is   acceptable  unless  it  is  close  to  the  area  being   treated.   •  Feel  free  to  bring  an  iPod®  or  your  favorite   music  CDs  with  you  on  the  day  of  your   treatment,  and  we  will  play  them  for  you  during   the  procedure.   (732) 557-3120 www.newjerseyck.com
  • 13. AddiAonal  Resources   99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com
  • 14. Our  Center   Opened  in  2011,  New  Jersey  CyberKnife  at  the  J.  Phillip  CiXa  Regional  Cancer  Center  is  ac=ve  in  clinical  research  and  combines   experienced  physicians  with  the  latest  medical  advances.  Our  state-­‐of-­‐the-­‐art  technology  offers  hope  to  pa=ents  in  New  Jersey  and   beyond.  Medical  Director  Dr.  David  D’Ambrosio  specialized  in  advanced  radia=on  therapies  and  his  exper=se  includes  intensity-­‐ modulated  and  stereotac=c  radia=on  therapies,  including  CyberKnife  radiosurgery.Our  center  provides  the  only  CyberKnife   technology  in  Ocean  County  New  Jersey.     If  you  or  a  loved  one  is  diagnosed  with  liver  cancer,  contact  New  Jersey  CyberKnife  to  schedule  a  consulta=on  with  our  physicians   to  determine  the  best  next  step  for  your  treatment  needs.     Medical  Director:  Dr.  David  D’Ambrosio     Chairman  of  RadiaAon  Oncology  at  Community  Medical   Center:  Dr.  Rajesh  Iyer     CyberKnife  Nurse:  Debbie  Moriarty,  RN,  MSN,  OCN       Connect  with  us       99 Route 37, West Toms River, NJ 08755 (732) 557-3120 www.newjerseyck.com