1. Mydriatics and Cycloplegics

2. The iris muscles
Iris, ciliary
body, sphincter and ciliary muscles are innervated by CN III

3. Agonists/Antagonists

4. Pharmocological Mydriasis
Mydro=to widen

5. CLINICAL PHARMACOLOGY
 This anticholinergic preparation blocks the responses of the
sphincter muscle of the iris and the ciliary muscle to
cholinergic stimulation, dilating the pupil (mydriasis).The
stronger preparation (1%) also paralyzes accommodation.
This preparation acts in 15-30 minutes and the duration of
activity is approximately 3-8 hours. Complete recovery from
mydriasis in some individuals may require 24 hours.The
weaker strength may be useful in producing mydriasis with
only slight cycloplegia. Heavily pigmented irides may require
more doses than lightly pigmented irides.

6. Rx for Pharmacological Mydriasis

7. Pharmacological Mydriasis

9. Phenylephrine

10. Clinical Indications for
Pharmocological mydriasis

11. Phenylephrine 1% or Cocaine

12. Cycloplegics

13. Pharmacological Cycloplegia

14. CLINICAL PHARMACOLOGY
 This anticholinergic preparation blocks the responses of the
sphincter muscle of the iris and the accommodative muscle of
the ciliary body to cholinergic stimulation, producing
pupillary dilation (mydriasis) and paralysis of accommodation
(cycloplegia). It acts rapidly, but has a shorter duration than
atropine. Maximal cycloplegia occurs within 25 to 75
minutes after instillation. Complete recovery of
accommodation usually takes 6 to 24 hours. Complete
recovery from mydriasis in some individuals may require
several days. Heavily pigmented irides may require more
doses than lightly pigmented irides.

21. Mydriatics and Cycloplegics