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SJS is a rare and serious condition of your skin
and mucous membranes.
oFlulike symptoms:
-cough
-fatigue
-fever
-headache
-muscle & joint pains
-sore throat
oThree-ringed sores (shades of pink and red) develop on skin
oSores & blisters spread to skin (possibly
eyes, genitals, lungs, stomach & colon as well)
oSkin eventually dies and falls off (you can lose 10-30% of your
body’s epidermis)
Tested for via biopsy, blood tests, x-rays, etc.
Histopathologic Findings- changes in the epidermal-
dermal area such as sub-epidermal blisters as well as
apoptosis of keratinocytes
Ocular Examination (conjunctival biopsy)- may show
subepithelial plasma cells and lymphocyte infiltration if
patient has active ocular disease
◊SJS is usually caused by an allergic reaction to a medication
(normally an antibiotic, anti-seizure medication or non-steroidal
anti-inflammatory medication).
◊Causes of SJS can’t always be identified
₪Fluid replacement
₪Stop use of medication causing reaction
₪Antacids (help prevent stomach/intestinal bleeding)
₪Topical antibiotics (helps treat any skin infections)
₪Hydrotherapy (clean wounds & remove dead tissue from skin)
₪Physical therapy (help arm & leg movement if on bed rest)
₪Surgery:
Debridement- cleans & removes dirt/dead tissue from infected area
Skin graft- help heal infected area
Death (due to infections, lung problems, etc.)
Possible skin scarring and pigment changes
Difficulty with swallowing, vision, urinating and skin for
life
May lose nails and hair forever
s
"Google." Google. N.p., n.d. Web. 28 Sept. 2013.
"Result Filters." National Center for Biotechnology Information. U.S. National Library of
Medicine, n.d. Web. 28 Sept. 2013.
Staff, Mayo Clinic. "Definition." Mayo Clinic. Mayo Foundation for Medical Education and
Research, 09 Apr. 2011. Web. 28 Sept. 2013.
"Stevens Johnson Syndrome Symptoms." Stevens-Johnson Syndrome Symptoms &
Treatment. N.p., n.d. Web. 28 Sept. 2013.
"Stevens-johnson Syndrome." - Care Guide. N.p., n.d. Web. 28 Sept. 2013.
"Stevens-Johnson Syndrome ." Stevens-Johnson Syndrome. N.p., n.d. Web. 28 Sept. 2013.

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Stevens-Johnson Syndrome

  • 1.
  • 2. SJS is a rare and serious condition of your skin and mucous membranes.
  • 3. oFlulike symptoms: -cough -fatigue -fever -headache -muscle & joint pains -sore throat oThree-ringed sores (shades of pink and red) develop on skin oSores & blisters spread to skin (possibly eyes, genitals, lungs, stomach & colon as well) oSkin eventually dies and falls off (you can lose 10-30% of your body’s epidermis)
  • 4. Tested for via biopsy, blood tests, x-rays, etc. Histopathologic Findings- changes in the epidermal- dermal area such as sub-epidermal blisters as well as apoptosis of keratinocytes Ocular Examination (conjunctival biopsy)- may show subepithelial plasma cells and lymphocyte infiltration if patient has active ocular disease
  • 5. ◊SJS is usually caused by an allergic reaction to a medication (normally an antibiotic, anti-seizure medication or non-steroidal anti-inflammatory medication). ◊Causes of SJS can’t always be identified
  • 6. ₪Fluid replacement ₪Stop use of medication causing reaction ₪Antacids (help prevent stomach/intestinal bleeding) ₪Topical antibiotics (helps treat any skin infections) ₪Hydrotherapy (clean wounds & remove dead tissue from skin) ₪Physical therapy (help arm & leg movement if on bed rest) ₪Surgery: Debridement- cleans & removes dirt/dead tissue from infected area Skin graft- help heal infected area
  • 7. Death (due to infections, lung problems, etc.) Possible skin scarring and pigment changes Difficulty with swallowing, vision, urinating and skin for life May lose nails and hair forever
  • 8. s "Google." Google. N.p., n.d. Web. 28 Sept. 2013. "Result Filters." National Center for Biotechnology Information. U.S. National Library of Medicine, n.d. Web. 28 Sept. 2013. Staff, Mayo Clinic. "Definition." Mayo Clinic. Mayo Foundation for Medical Education and Research, 09 Apr. 2011. Web. 28 Sept. 2013. "Stevens Johnson Syndrome Symptoms." Stevens-Johnson Syndrome Symptoms & Treatment. N.p., n.d. Web. 28 Sept. 2013. "Stevens-johnson Syndrome." - Care Guide. N.p., n.d. Web. 28 Sept. 2013. "Stevens-Johnson Syndrome ." Stevens-Johnson Syndrome. N.p., n.d. Web. 28 Sept. 2013.