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LUNG CANCER
INCIDENCE
• Usually occur in males
• Also in smoking females
• After 50 yrs
• Metastasis from other areas [non
smokers]
ETIOLOGY
• Cigarette smoking
risk of lung cancer= exposure to
cigarettes measured by,
– total number of cigarettes smoked in a
lifetime,
– Earlier age of smoking onset
– Depth of inhalation
– Tar and nicotine content
– Use of unfiltered cigarettes
Passive smoking/ side stream smoke
Usage of pipes and cigars.
Employees in mining, chemical/ petroleum
manufacturing
Inhalation of carcinogens
 Asbetos
 Nickel
 Radon
 Uranium
 Arsenic
 hydrocarbons
PATHOPHYSIOLOGY
Bronchogenic growths
Hyper secretion of mucus
Desquamation of cells
Reactive hyperplasia of the basal cells
Metaplasia of normal respiratory epithelium to stratified squamous
cells metastasis
CLASSIFICATION
• NON SMALL CELL LUNG CANCER
[NSCLC]
• SMALL CELL LUNG CANCER
[SCLC]
NSCLC
TYPES FEATURES
Squamous cell
carcinoma
Always associated with
cigarette smoking and
exposure to
environment
carcinogens
Adenocarcinoma Associated with lung
scarring and chronic
interstitial fibrosis, not
related with cigarette
smoking.
Large cell
undifferentiated
carcinoma
High correlation with
cigarette smoking and
exposure to
carcinogens
SCLC
TYPES CRITERIA
SMALL CELL
ANAPLASTIC
UNDIFFERENTIATE
D [OAT CELL]
Associated with
cigarette smoking,
exposure to
environmental
carcinogens
Very poor prognosis
CLINICAL
MANIFESTATIONSMostly clinically silent
Metastasis occurs before s/s persists
Persistent pneumonitis- fever, chills, and cough
Persistent and productive cough
Blood tinged sputum
Chest pain
Dyspnea
Auscultatory wheeze
• Anorexia
• Fatigue
• Weight loss
• Nausea & vomiting
• Hoarseness
• Unilateral paralysis of diaphragm
• Dysphagia
DIAGNOSTICS
 History & Physical Examination
 Chest X-ray
 Ssputum for cytologic study
 Bronchoscopy
 CT scan
 MRI
 Positron Emission tomography
 Spirometry
 Mediastinoscopy
 Video Assisted Thoracoscopy
 Pulmonary angiography
 Lung Scan
 Fine needle aspiration
MANAGEMENT
• Surgery
• Radiation therapy
• Chemotherapy
• Biologic therapy
• Bronchoscopic laser therapy
• Phototherapy
• Airway stenting
Types of Lung Resections
Lobectomy: a single lobe of lung is removed
Bilobectomy: two lobes of the lung are removed
Sleeve resection: cancerous lobe(s) is removed and a
segment of the main bronchus is resected
Pneumonectomy: removal of entire lung
Segmentectomy: a segment of the lung is removed
Wedge resection: removal of a small, pie-shaped area of
the segment
Chest wall resection with removal of cancerous lung
tissue: for cancers that have invaded the chest wall
NURSING MANAGEMENT
Ineffective airway clearance r/t increased
tracheobronchial secretions and presence of
tumor.
Acute pain r/t pressure of tumor on
sorrounding structures and erosion of
tissues
Imbalanced nutrition, less than body
requirement r/t increased metabolic
demands, increased secretions, weakness
and anorexia.
• Anxiety r/t lack of knowledge of
diagnosis and unknown treatments
• Ineffective health maintenance r/t
lack of knowledge about the disease
process and therapeutic regimen
• Ineffective breathing pattern r/t
decreased lung capacity
GOALS
• Effecting breathing pattern
• Adequate airway clearance
• Adequate oxygenation of tissues
• Minimal or no pain
• A realistic attitude toward treatment
and prognosis.

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Lung cancer

  • 2. INCIDENCE • Usually occur in males • Also in smoking females • After 50 yrs • Metastasis from other areas [non smokers]
  • 3. ETIOLOGY • Cigarette smoking risk of lung cancer= exposure to cigarettes measured by, – total number of cigarettes smoked in a lifetime, – Earlier age of smoking onset – Depth of inhalation – Tar and nicotine content – Use of unfiltered cigarettes
  • 4. Passive smoking/ side stream smoke Usage of pipes and cigars. Employees in mining, chemical/ petroleum manufacturing Inhalation of carcinogens  Asbetos  Nickel  Radon  Uranium  Arsenic  hydrocarbons
  • 5. PATHOPHYSIOLOGY Bronchogenic growths Hyper secretion of mucus Desquamation of cells Reactive hyperplasia of the basal cells Metaplasia of normal respiratory epithelium to stratified squamous cells metastasis
  • 6. CLASSIFICATION • NON SMALL CELL LUNG CANCER [NSCLC] • SMALL CELL LUNG CANCER [SCLC]
  • 7. NSCLC TYPES FEATURES Squamous cell carcinoma Always associated with cigarette smoking and exposure to environment carcinogens Adenocarcinoma Associated with lung scarring and chronic interstitial fibrosis, not related with cigarette smoking. Large cell undifferentiated carcinoma High correlation with cigarette smoking and exposure to carcinogens
  • 8. SCLC TYPES CRITERIA SMALL CELL ANAPLASTIC UNDIFFERENTIATE D [OAT CELL] Associated with cigarette smoking, exposure to environmental carcinogens Very poor prognosis
  • 9. CLINICAL MANIFESTATIONSMostly clinically silent Metastasis occurs before s/s persists Persistent pneumonitis- fever, chills, and cough Persistent and productive cough Blood tinged sputum Chest pain Dyspnea Auscultatory wheeze
  • 10. • Anorexia • Fatigue • Weight loss • Nausea & vomiting • Hoarseness • Unilateral paralysis of diaphragm • Dysphagia
  • 11. DIAGNOSTICS  History & Physical Examination  Chest X-ray  Ssputum for cytologic study  Bronchoscopy  CT scan  MRI  Positron Emission tomography  Spirometry  Mediastinoscopy  Video Assisted Thoracoscopy  Pulmonary angiography  Lung Scan  Fine needle aspiration
  • 12. MANAGEMENT • Surgery • Radiation therapy • Chemotherapy • Biologic therapy • Bronchoscopic laser therapy • Phototherapy • Airway stenting
  • 13. Types of Lung Resections Lobectomy: a single lobe of lung is removed Bilobectomy: two lobes of the lung are removed Sleeve resection: cancerous lobe(s) is removed and a segment of the main bronchus is resected Pneumonectomy: removal of entire lung Segmentectomy: a segment of the lung is removed Wedge resection: removal of a small, pie-shaped area of the segment Chest wall resection with removal of cancerous lung tissue: for cancers that have invaded the chest wall
  • 14.
  • 15. NURSING MANAGEMENT Ineffective airway clearance r/t increased tracheobronchial secretions and presence of tumor. Acute pain r/t pressure of tumor on sorrounding structures and erosion of tissues Imbalanced nutrition, less than body requirement r/t increased metabolic demands, increased secretions, weakness and anorexia.
  • 16. • Anxiety r/t lack of knowledge of diagnosis and unknown treatments • Ineffective health maintenance r/t lack of knowledge about the disease process and therapeutic regimen • Ineffective breathing pattern r/t decreased lung capacity
  • 17. GOALS • Effecting breathing pattern • Adequate airway clearance • Adequate oxygenation of tissues • Minimal or no pain • A realistic attitude toward treatment and prognosis.