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3.linctuses

  1. 1. Mr. Pankaj Kusum Ramdas Khuspe M. Pharmacy (Pharmaceutics)
  2. 2. 1. Definition 2. Formulation 3. Storage Mr. Pankaj Kusum Ramdas Khuspe
  3. 3. 1. Define linctuses. 2. What is linctuses. 3. Give the reasons for following statements:  Linctuses should be taken in small doses without dilution. Mr. Pankaj Kusum Ramdas Khuspe
  4. 4. Definition:  viscous,  Monophasic liquid preparation  containing a high concentration of syrup  intended to sipped and  swallowed slowly  for treatment of cough. Mr. Pankaj Kusum Ramdas Khuspe
  5. 5. “Linctuses are viscous, monophasic liquid preparation containing a high concentration of syrup intended to sipped and swallowed slowly for treatment of cough.” Mr. Pankaj Kusum Ramdas Khuspe
  6. 6. 1. Demulcent. 2.Sedative. 3. Expectorant action. Mr. Pankaj Kusum Ramdas Khuspe
  7. 7. 1. Vehicles: 2. Adjuncts: Used to improve Safety, efficacy and palatability. 1. Chemical Stabilizer: 2. Preservative: 3. Coloring Agent: 4. Flavoring agent: Mr. Pankaj Kusum Ramdas Khuspe
  8. 8. 1. Vehicles: Syrup, (Tolu syrup), glycerin, sorbitol. 1. Adjuncts: Used to improve Safety, efficacy and palatability. 1. Chemical Stabilizer:  Mostly stable because of syrup. 2. Preservative:  High concentration of syrup acting as preservative.  Tolu syrup has antibacterial action due to benzoic acid and cinnamic acid present in it.  Benzoic acid in codeine phosphate linctuses. 3. Coloring Agent:  Coal tar dyes. 4. Flavoring agent:  black current syrup, lemon syrup, oxymel and benzaldehyde etc.Mr. Pankaj Kusum Ramdas Khuspe
  9. 9. Codeine Phosphate linctus BPC Rx Codeine phosphate 3.0 g Lemon syrup 200 ml Benzoic acid 20 ml Chloroform spirit 20 ml Compound tartrazine solution 10 ml Syrup q. s to 1000 ml Prepare linctus, send 30 ml Direction: Sip and swallow slowly (without aid of water) Mr. Pankaj Kusum Ramdas Khuspe
  10. 10. Linctuses are supplied in well closed air tight container having screw cap stored in a cool place, protected from light. Mr. Pankaj Kusum Ramdas Khuspe
  11. 11. Mr. Pankaj Kusum Ramdas Khuspe
  12. 12. Mr. Pankaj Kusum Ramdas Khuspe

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