5. SATURATION CURVE [Drug] nM [DR] K D At equilibrium, the dissociation constant is K D and the affinity is K A = 1/K D Thus when [D] = K D , half the total number of receptors will be occupied. www.freelivedoctor.com
17. SEMILOG DOSE-RESPONSE CURVE RANK ORDER OF POTENCY: A > B > C > D www.freelivedoctor.com A B C D EFFECT Log [Dose]
18. SEMILOG DOSE-RESPONSE CURVE RANK ORDER OF POTENCY: A > B > C > D RANK ORDER OF EFFICACY: A = C > B > D ED50 www.freelivedoctor.com A B C D RESPONSE